MAPK
Le MAPK sono una famiglia di chinasi proteiche coinvolte in una varietà di processi cellulari, tra cui crescita, proliferazione, differenziazione e risposte allo stress. La via di segnalazione MAPK è composta da diversi livelli, tra cui ERK, JNK e p38 MAPK, ciascuno con ruoli distinti nella funzione cellulare. La disregolazione della segnalazione MAPK è collegata al cancro, alle malattie infiammatorie e ai disturbi metabolici. Presso CymitQuimica, offriamo una vasta gamma di inibitori e attivatori delle MAPK per supportare la tua ricerca in biologia cellulare, trasduzione del segnale e meccanismi delle malattie.
Trovati 892 prodotti di "MAPK"
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HPK1-IN-4
CAS:<p>HPK1-IN-4 is an HPK1 (MAPK41) inhibitor with an IC 50 of 0.061 nM. HPK1-IN-4 is often used as a preclinical immunotherapy tool compound.</p>Formula:C23H26N6O3Purezza:97.2%Colore e forma:SolidPeso molecolare:434.49Olomoucine
CAS:<p>Olomoucine hinders Cdk2, Cdc2, CDK5, ERK1, regulates the cell cycle, and fights melanoma; IC50s: 3-25 µM.</p>Formula:C15H18N6OPurezza:99.77%Colore e forma:White Crystalline PowderPeso molecolare:298.34TAK1-IN-3
CAS:TAK1-IN-3 is a novel ATP-competitive TAK1 inhibitor for the study of cancer.Formula:C16H19N3O2SPurezza:98.88%Colore e forma:SolidPeso molecolare:317.41S6K1-IN-DG2
CAS:S6K1-IN-DG2(S6K1InhibitorDG2) is a potent p70S6K inhibitor with an IC50 value of less than 100 nM.Formula:C16H17BrN6OPurezza:99.99%Colore e forma:SolidPeso molecolare:389.25Enniatin B1
CAS:<p>Enniatin B1, a Fusarium mycotoxin, crosses the blood-brain barrier and modulates ERK, NF-κB, and ACAT with an IC50 of 73 μM.</p>Formula:C34H59N3O9Purezza:98%Colore e forma:SolidPeso molecolare:653.858LC-2
CAS:LC-2 (PROTAC KRASG12C Degrader-LC-2) is a novel von Hippel-Lindau-based PROTAC degrader of endogenous KRAS G12C with a DC50 between 0.25 and 0.76 μM.LC-2 is aFormula:C59H71ClFN11O7SPurezza:98%Colore e forma:SolidPeso molecolare:1132.78Anti-ERK2 Antibody (5V598)
Anti-ERK2 Antibody (5V598) is a Rabbit antibody targeting ERK2. Anti-ERK2 Antibody (5V598) can be used in ELISA.Colore e forma:Odour LiquidAnti-ERK2 Antibody (4F551)
Anti-ERK2 Antibody (4F551) is a Rabbit antibody targeting ERK2. Anti-ERK2 Antibody (4F551) can be used in ELISA,FCM.Colore e forma:Odour LiquidAnti-ERK2 Antibody (9C922)
Anti-ERK2 Antibody (9C922) is a Mouse antibody targeting ERK2. Anti-ERK2 Antibody (9C922) can be used in WB,ELISA.Colore e forma:Odour LiquidRAS GTPase inhibitor 1
CAS:RAS GTPase inhibitor 1 is a RAS GTPase inhibitor with potential antitumor activity.Formula:C27H28ClF4N5O2Purezza:98.43%Colore e forma:SolidPeso molecolare:565.99Enniatin B
CAS:Enniatins B decreases the activation of ERK (p44/p42).Formula:C33H57N3O9Purezza:98%Colore e forma:SolidPeso molecolare:639.831Tunlametinib
CAS:Tunlametinib is a MEK1/2 inhibitor (IC50=1.9 nM) for treating RAS/RAF-driven cancers.Formula:C16H12F2IN3O3SPurezza:98.72%Colore e forma:SolidPeso molecolare:491.25Cephradine (Standard)
CAS:Cephradine (Standard) is the standard substance of Cephradine, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Cephradine (Anspor) is a beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity.Formula:C16H19N3O4SPeso molecolare:349.40TRPM4 inhibitor 8
CAS:TRPM4 inhibitor 8 is an inhibitor of Transient receptor potential melastatin 4(TRPM4) which contributes to viability, migration, cell cycle shift, and adhesion.Formula:C11H17BrN2Purezza:99.84%Colore e forma:SolidPeso molecolare:257.17JH295
CAS:JH295: potent, selective Nek2 inhibitor (IC50 = 770 nM), irreversibly targets Cys22, no effect on Cdk1, Aurora B, Plk1, or spindle mechanisms.Formula:C18H16N4O2Colore e forma:SolidPeso molecolare:320.352MLK-IN-1
CAS:MLK-IN-1 is a potent and selective mixed-lineage kinase 3 (MLK-3) inhibitor, showing excellent brain penetration and high specificity for MLK-3. MLK-IN-1 at 100 nM supports sustained axonogenesis in cultures challenged with HIV-1 Tat-activated microglia and protects neuronal cells from Tat-induced damage, establishing it as a valuable probe for neuroinflammation and neurodegeneration research.Formula:C23H20N4O3SPurezza:99.74%Colore e forma:SolidPeso molecolare:432.5Deltarasin HCl
CAS:Deltarasin hinders KRAS-PDEδ, impairs cancer cell growth via a PDEδ pocket, disrupting RAS/RAF signaling and autophagy.Formula:C40H37N5O·xHClColore e forma:SolidPeso molecolare:713.144IACS-13909
CAS:IACS-13909 (BBP-398), a specific and potent allosteric inhibitor of SHP2, that suppresses signaling through the MAPK pathway.Formula:C17H18Cl2N6Purezza:98.8%Colore e forma:SolidPeso molecolare:377.27Nardosinone
CAS:Nardosinone inhibits H9c2 cell hypertrophy, protects neurons from OGD, and boosts neurite outgrowth by modifying key signaling pathways.Formula:C15H22O3Purezza:98.82% - 99%Colore e forma:SolidPeso molecolare:250.33CC-90001
CAS:CC-90001 is an orally administered c-Jun N-terminal kinase (JNK) inhibitor with bias for JNK1 over JNK2.Formula:C16H27N5O2Purezza:99.96%Colore e forma:SolidPeso molecolare:321.42
