MAPK
Le MAPK sono una famiglia di chinasi proteiche coinvolte in una varietà di processi cellulari, tra cui crescita, proliferazione, differenziazione e risposte allo stress. La via di segnalazione MAPK è composta da diversi livelli, tra cui ERK, JNK e p38 MAPK, ciascuno con ruoli distinti nella funzione cellulare. La disregolazione della segnalazione MAPK è collegata al cancro, alle malattie infiammatorie e ai disturbi metabolici. Presso CymitQuimica, offriamo una vasta gamma di inibitori e attivatori delle MAPK per supportare la tua ricerca in biologia cellulare, trasduzione del segnale e meccanismi delle malattie.
Trovati 925 prodotti per "MAPK".
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KB-5246
CAS:KB-5246, displays antibacterial activities.is a tetracyclic quinolone.Formula:C18H17ClFN3O4SPurezza:98%Colore e forma:SolidPeso molecolare:425.86(S)-CCG-1423
(S)-CCG-1423, a stereoisomer, inhibits Rho to block myocardin-related transcription factor A & serum response signaling.Formula:C18H13ClF6N2O3Purezza:98%Colore e forma:SolidPeso molecolare:454.8B-Raf IN 7
CAS:"B-Raf IN 7 inhibits B-Raf (IC50: 110.23 nM); fights colon, breast, liver, cervical, prostate cancers (IC50: 7.50-12.83 μM)."Formula:C15H16N6O3Colore e forma:SolidPeso molecolare:328.33TOPK-p38/JNK-IN-1
CAS:TOPK-p38/JNK-IN-1 (Compound B12) is an orally active inhibitor of the TOPK-p38/JNK signaling pathway, with an IC50 value of 2.14 μM for the inhibition of NOFormula:C17H15F3N2O4Colore e forma:SolidPeso molecolare:368.31(R)-PD 0325901CL
CAS:(R)-PD 0325901CL, a PD 0325901CL isomer, is a MEK inhibitor used in cancer research, effective against cancer cells in vitro and in vivo.Formula:C16H14ClF2IN2O4Colore e forma:SolidPeso molecolare:498.65KRAS inhibitor-6
CAS:KRAS inhibitor-6 is a potent KRAS G12C inhibitor.Formula:C27H30ClF2N5O3Purezza:98%Colore e forma:SolidPeso molecolare:546.01J30-8
CAS:J30-8 is a JNK3 inhibitor (IC50: 40 nM) with neuroprotective activity and can be used to study neurodegenerative diseases such as Alzheimer's disease.Formula:C17H9ClFN3O2SPurezza:99.90%Colore e forma:Red SolidPeso molecolare:373.79BMS-214662 hydrochloride
CAS:BMS-214662: a farnesyltransferase inhibitor, nonsedating benzodiazepine, blocks Ras-related tumorigenesis.Formula:C25H24ClN5O2S2Colore e forma:SolidPeso molecolare:526.07(2Z,3Z)-U0126
CAS:U0126 selectively inhibits MEK1/2, blocks MAPK/ERK signaling, and suppresses Ki-ras-induced cell growth, with IC50s of 72 nM and 58 nM for MEK1/2.Formula:C18H16N6S2Colore e forma:SolidPeso molecolare:380.49RAS inhibitor Abd-7
CAS:RAS inhibitor Abd-7 is a RAS binding inhibitor, which can block the RAS signal pathway.Formula:C23H25N3O3Colore e forma:White SolidPeso molecolare:391.46CK1-IN-2
CAS:CK1-IN-2 (compound Nr.4) is a potent CK1 inhibitor p38a, and is used in DUX4 overexpression-associated diseases, such as muscular dystrophy.Formula:C17H12FN3O2Purezza:99.31%Colore e forma:SolidPeso molecolare:309.29SR-3737
CAS:SR-3737 is potent both JNK3 and p38 inhibitor.Formula:C29H25FN4O4Purezza:98%Colore e forma:SolidPeso molecolare:512.53RAF-IN-1
CAS:RAF-IN-1 inhibits cRAF, BRAF and BRAFV600E, with GI50 3.4 and 2.9 nM in mutant cell lines.Formula:C26H22F3N3O4Purezza:99.62%Colore e forma:White SolidPeso molecolare:497.47KRAS inhibitor-4
CAS:KRAS inhibitor-4 developed as anticancer agents, is a potent KRAS inhibitor.Formula:C30H39ClN8OPurezza:98%Colore e forma:SolidPeso molecolare:563.14Anti-inflammatory agent 33
CAS:Agent 33: potent p38α inhibitor, reduces NO, iNOS, COX-2, p-p38α, p-MK2; shows anti-inflammatory effects.Formula:C22H15N3O5SColore e forma:SolidPeso molecolare:433.44RSK2-IN-3
CAS:RSK2-IN-3 (Compound 26) is a covalent, reversible inhibitor of RPS6KA3 (RSK2) kinase.Formula:C24H26N4O5Colore e forma:SolidPeso molecolare:450.49MLKL-IN-5
CAS:MLKL-IN-5 is a potent MLKL inhibitor blocking necroptosis signaling.Formula:C18H20N6O4SPurezza:98.77%Colore e forma:Pink SolidPeso molecolare:416.45(R)-CE3F4
CAS:(R)-CE3F4 is a selective inhibitor of exchange protein directly activated by cAMP isoform 1 (Epac1)(IC50 of 4.2 μM),Formula:C11H10Br2FNOColore e forma:SolidPeso molecolare:351.01GABAB receptor antagonist 1
CAS:(E)-GABAB receptor antagonist 1 decreases GABA-induced IP3 (inositol trisphosphate) production with IC50 of 37.9 μM.GABAB receptor antagonist 1 is a selectiveFormula:C18H24O4Purezza:98%Colore e forma:SolidPeso molecolare:304.38B-Raf IN 6
CAS:B-Raf IN 6: potent B-Raf kinase inhibitor, IC50 of 1.7 nM, doesn't target PXR, metabolically stable, potential in cancer research.Formula:C24H21F3N6O2S2Colore e forma:SolidPeso molecolare:546.59
