MAPK
Le MAPK sono una famiglia di chinasi proteiche coinvolte in una varietà di processi cellulari, tra cui crescita, proliferazione, differenziazione e risposte allo stress. La via di segnalazione MAPK è composta da diversi livelli, tra cui ERK, JNK e p38 MAPK, ciascuno con ruoli distinti nella funzione cellulare. La disregolazione della segnalazione MAPK è collegata al cancro, alle malattie infiammatorie e ai disturbi metabolici. Presso CymitQuimica, offriamo una vasta gamma di inibitori e attivatori delle MAPK per supportare la tua ricerca in biologia cellulare, trasduzione del segnale e meccanismi delle malattie.
Trovati 895 prodotti di "MAPK"
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SR 3576
CAS:JNK3 inhibitor, potent and selectiveFormula:C27H27N5O5Purezza:98%Colore e forma:SolidPeso molecolare:501.53Angiogenesis inhibitor BT2
CAS:BT2 inhibits angiogenesis, vascular permeability by targeting ERK, FosB, VCAM-1, and related genes, affecting MEK1 and suppressing retinal markers.Formula:C18H18N2O4Colore e forma:SolidPeso molecolare:326.35ADTL-EI1712
CAS:ADTL-EI1712: ERK1/2/5 inhibitor (ERK1 IC50=40.43nM, ERK5=64.5nM), blocks HL-60/MKN74 cell growth, not HeLa; effective in MKN74 mouse model.Formula:C22H18Cl2N4O2S2Colore e forma:SolidPeso molecolare:505.44SOS1-IN-3
CAS:SOS1-IN-3 is an effective inhibitor of SOS1 (son of sevenless homolog 1) (IC50=5 nM). SOS1-IN-3 shows antitumor activity.Formula:C21H21F3N4OColore e forma:SolidPeso molecolare:402.41MEK-IN-4
CAS:MEK-IN-4 is a MEK inhibitor that can be used to study inflammatory diseases and cancer.Formula:C21H18N4OSPurezza:98.35% - 99.16%Colore e forma:SolidPeso molecolare:374.46MEK inhibitor
CAS:MEK inhibitor is a MEK receptor and cell cycle protein/CDK complex inhibitor with antitumor activity that can be used to study tumor cell proliferation.Formula:C26H26N4O2Purezza:97.48%Colore e forma:SolidPeso molecolare:426.51JX 401
CAS:JX 401 is a p38α inhibitor.Formula:C21H25NO2SPurezza:98%Colore e forma:SolidPeso molecolare:355.493,4-Dephostatin
CAS:3,4-Dephostatin is an inhibitor of the interactions of CFTR-associated ligand (CAL) and PSD-95/Dlg1/ZO-1 (PDZ) domain.Formula:C7H8N2O3Colore e forma:SolidPeso molecolare:168.15SB 204900
CAS:SB 204900 inhibit the release of histamine and TNF-α from RBL-2H3 cells.Formula:C18H17NO2Colore e forma:SolidPeso molecolare:279.33HPK1-IN-29
CAS:"HPK1-IN-29 suppresses HPK1, boosting anti-tumor immunity; potential for immune disease research."Formula:C26H18F3N5O2Colore e forma:SolidPeso molecolare:489.45NSC-658497
CAS:NSC-658497 is a SOS1-Ras interaction inhibitor that acts by dose-dependently inhibiting SOS1 GEF activity.Formula:C20H10N2O6S2Purezza:98%Colore e forma:SolidPeso molecolare:438.43DDO3711
CAS:"DDO3711, a PHORC, links an ASK1 inhibitor to a PP5 activator, inhibiting ASK1 (IC50=164.1 nM), dephosphorylating p-ASK1, and showing anti-cancer potential."Formula:C42H41N9O6Colore e forma:SolidPeso molecolare:767.83AKP-001
CAS:AKP-001 is a selective inhibitor of MAPK of the p38α isoform and is used in the study of immune and digestive disorders.Formula:C21H13ClF2N4O2Purezza:99.50% - 99.92%Colore e forma:SolidPeso molecolare:426.8NMDAR/TRPM4-IN-2
CAS:Potent NMDAR/TRPM4-IN-2 blocks NMDAR/TRPM4, protects brain and retinal neurons, and prevents mitochondrial dysfunction with an IC50 of 2.1 μM.Formula:C11H19BrCl2N2Purezza:99.75%Colore e forma:SolidPeso molecolare:330.092Cot inhibitor-1
CAS:Cot inhibitor-1 selectively blocks Tpl2 kinase, reducing TNF-alpha in blood (IC50: 5.7 nM). It may treat arthritis, IBD, and certain cancers.Formula:C27H27Cl2FN8Purezza:98.87%Colore e forma:SolidPeso molecolare:553.46JNK-IN-11
CAS:JNK-IN-11 inhibits JNK1/2/3 (IC50: 2.2/21.4/1.8 μM); promising for Alzheimer's/Parkinson's research.Formula:C12H11NO3S2Purezza:98.82%Colore e forma:SolidPeso molecolare:281.35DS12881479
CAS:DS12881479 can be used in cancer research which is a potent and selective inhibitor of Mnk1(IC 50 =21 nM) [1].Formula:C16H19N3OSPurezza:99.85%Colore e forma:SolidPeso molecolare:301.41MKK7-COV-9
CAS:MKK7-COV-9 is an MKK7 inhibitor that inhibits MKK7-induced protein-protein interactions and interrupts the activation of primary B cells in response to LPS.Formula:C18H16N4O2Purezza:99.73% - 99.83%Colore e forma:SolidPeso molecolare:320.35GSK2008607
CAS:<p>GSK2008607 is a potent B-RafV600E inhibitor with anticancer activity and can be used to study breast, colorectal, melanoma, thyroid, and ovarian cancers.</p>Formula:C31H28F3N7O3S2Purezza:99.36%Colore e forma:SolidPeso molecolare:667.72p38 MAPK Inhibitor
CAS:p38 MAPK inhibitor is a potent inhibitor of p38 MAP kinase (IC50 = 35 nM). It inhibits senescence induced by the oncogene RAS.Formula:C20H13ClFN3OPurezza:99.91%Colore e forma:SolidPeso molecolare:365.79
