Ras
Le proteine Ras sono piccole GTPasi che agiscono come interruttori molecolari nella via di segnalazione MAPK, controllando la crescita, la differenziazione e la sopravvivenza cellulare. Ras attivato avvia una cascata di segnalazione che include Raf, MEK ed ERK, portando a varie risposte cellulari. Le mutazioni nei geni Ras sono comuni nei tumori, rendendo Ras un importante focus della ricerca sul cancro. Presso CymitQuimica, offriamo una gamma di modulatori di Ras per supportare la tua ricerca in biologia del cancro, trasduzione del segnale e sviluppo terapeutico.
Trovati 156 prodotti di "Ras"
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K-Ras(G12C) inhibitor 12
CAS:K-Ras(G12C) inhibitor 12 is an allosteric inhibitor of oncogenic K-Ras(G12C).Formula:C15H17ClIN3O3Purezza:97.16%Colore e forma:SolidPeso molecolare:449.67MLS000532223
CAS:<p>MLS000532223 is a selectiveRho family GTPases inhibitor(EC50 : 16 μM to 120 μM).</p>Formula:C15H9NO3Purezza:98.6%Colore e forma:SolidPeso molecolare:251.24Antineoplaston A10
CAS:Antineoplaston A10 (NSC-648539) is a Ras inhibitor potentially for the treatment of glioma, lymphoma, astrocytoma and breast cancer.Formula:C13H14N2O3Purezza:99.42%Colore e forma:SolidPeso molecolare:246.26K-Ras(G12C) inhibitor 9
CAS:K-Ras(G12C) inhibitor 9 is an allosteric inhibitor of oncogenic K-Ras(G12C).Formula:C16H21ClIN3O4SPurezza:97.33% - 97.45%Colore e forma:SolidPeso molecolare:513.78CCG-100602
CAS:CCG-100602 inhibits RhoA/C-mediated, SRF-driven luciferase expression in PC-3 prostate cancer cells (IC50 :9.8 μM).Formula:C21H17ClF6N2O2Purezza:99.58%Colore e forma:SolidPeso molecolare:478.82ARS-853
CAS:<p>ARS-853 is an inhibitor of K-RASG12C(IC50 : 2.5 μM), a mutant form of K-RAS that accumulates in the active GTP-bound state in certain cancer cells</p>Formula:C22H29ClN4O3Purezza:97.43% - 98.4%Colore e forma:SolidPeso molecolare:432.94FTI-277 hydrochloride
CAS:FTI-277 HCl: potent FTase inhibitor, IC50 500 pM, 100x more selective than GGTase I.Formula:C22H30ClN3O3S2Purezza:97.57% - 97.61%Colore e forma:SolidPeso molecolare:484.07ZCL278
CAS:ZCL278 is a selective Cdc42 GTPase inhibitor.Formula:C21H19BrClN5O4S2Purezza:96.29% - 99.72%Colore e forma:SolidPeso molecolare:584.89EHop-016
CAS:EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 μM for Rac1 in MDA-MB-231 and MDA-MB-435 cells, equally effective inhibition for Rac3.Formula:C25H30N6OPurezza:98.99% - >99.99%Colore e forma:SolidPeso molecolare:430.55Phellodendrine chloride
CAS:Phellodendrine chloride combats kidney inflammation by blocking macrophage and T cell activity in glomeruli.Formula:C20H24ClNO4Purezza:98.85% - 99.05%Colore e forma:SolidPeso molecolare:377.86NSC 23766 trihydrochloride
CAS:NSC 23766 trihydrochloride (Rac1 Inhibitor) is an inhibitor of Rac GTPase targeting Rac activation by GEFs; no inhibitory for RhoA or Cdc42.Formula:C24H35N7·3HClPurezza:96.48% - 99.54%Colore e forma:SolidPeso molecolare:530.96ARS-1620
CAS:<p>ARS-1620 is a covalent inhibitor of K-RASG12C.</p>Formula:C21H17ClF2N4O2Purezza:98.86%Colore e forma:SolidPeso molecolare:430.84(S)-AMG-510
CAS:<p>(S)-AMG-510 is the S-type compound of AMG-510 (Sotorasib), which effectively and selectively inhibits KRASG12C.Cost-effective and quality-assured.</p>Formula:C30H30F2N6O3Purezza:99.05% - 99.76%Colore e forma:SolidPeso molecolare:560.594BAY-293
CAS:<p>BAY-293 is a potent, cell-active SOS1 inhibitor that disrupts the KRAS-SOS1 interaction (IC50: 21 nM).</p>Formula:C25H28N4O2SPurezza:97.16%Colore e forma:SolidPeso molecolare:448.58ZT-12-037-01
CAS:Zt-12-037-01 is a ATP competitive STK19 inhibitor（IC50 values of 23.96 nM and 27.94 nM for STK19 (WT) and STK19 (D89N),respectively).Formula:C21H31N5O2Purezza:99.56%Colore e forma:SolidPeso molecolare:385.5SCH54292
CAS:SCH-54292 is a GDP exchange inhibitor.Formula:C24H28N2O9SPurezza:95.65%Colore e forma:SolidPeso molecolare:520.55APS6-45
CAS:<p>APS6-45 inhibits RAS/MAPK signaling and exhibits anti-tumor activity.</p>Formula:C23H16F8N4O3Purezza:99.39%Colore e forma:SolidPeso molecolare:548.39RBC8
CAS:RBC8 is a specific GTPases RalA/RalB inhibitor by inhibiting the binding of Ral to its effector RALBP1, no inhibition on the GTPases RhoA and Ras.Formula:C25H20N4O3Purezza:98.44% - 99.81%Colore e forma:SolidPeso molecolare:424.45ML141
CAS:ML141 (CID-2950007) is an effective, specific and reversible non-competitive inhibitor of Rho family GTPase cdc42 (IC50: 200 nM).Formula:C22H21N3O3SPurezza:99.36% - 99.56%Colore e forma:SolidPeso molecolare:407.491A-116
CAS:<p>1A-116 is a specific Rac1 inhibitor.</p>Formula:C16H16F3N3Purezza:99.71%Colore e forma:SolidPeso molecolare:307.31
