Ras
Le proteine Ras sono piccole GTPasi che agiscono come interruttori molecolari nella via di segnalazione MAPK, controllando la crescita, la differenziazione e la sopravvivenza cellulare. Ras attivato avvia una cascata di segnalazione che include Raf, MEK ed ERK, portando a varie risposte cellulari. Le mutazioni nei geni Ras sono comuni nei tumori, rendendo Ras un importante focus della ricerca sul cancro. Presso CymitQuimica, offriamo una gamma di modulatori di Ras per supportare la tua ricerca in biologia del cancro, trasduzione del segnale e sviluppo terapeutico.
Trovati 167 prodotti per "Ras".
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FTI-277 hydrochloride
CAS:FTI-277 HCl: potent FTase inhibitor, IC50 500 pM, 100x more selective than GGTase I.Formula:C22H30ClN3O3S2Purezza:97.57% - 97.61%Colore e forma:SolidPeso molecolare:484.07Ref: TM-T2700
1mg50,00€2mg70,00€5mg90,00€1mL*10mM (DMSO)102,00€10mg158,00€25mg304,00€50mg497,00€100mg708,00€200mg964,00€ARS-853
CAS:ARS-853 is an inhibitor of K-RASG12C(IC50 : 2.5 μM), a mutant form of K-RAS that accumulates in the active GTP-bound state in certain cancer cellsFormula:C22H29ClN4O3Purezza:97.43% - 98.4%Colore e forma:SolidPeso molecolare:432.94Ref: TM-T7414
1mg142,00€1mL*10mM (DMSO)338,00€5mg353,00€10mg525,00€25mg843,00€50mg1.144,00€100mg1.549,00€500mg3.087,00€Y16
CAS:Y16 is a G protein-coupled Rho GEFs inhibitor and also a specific inhibitor of LARG with a Kd of 76 nM.Cost-effective and quality-assured.Formula:C24H20N2O3Purezza:98.26% - 99.85%Colore e forma:SolidPeso molecolare:384.43Ref: TM-T3553
1mg34,00€2mg48,00€5mg70,00€1mL*10mM (DMSO)77,00€10mg109,00€25mg177,00€50mg263,00€100mg389,00€CCG-222740
CAS:CCG-222740 is an inhibitor of Rho/MRTF pathwayFormula:C23H19ClF2N2O3Purezza:98.76%Colore e forma:SolidPeso molecolare:444.86Ref: TM-T7764
2mg39,00€5mg62,00€1mL*10mM (DMSO)66,00€10mg94,00€25mg172,00€50mg260,00€100mg371,00€200mg530,00€6H05 (TFA)
CAS:6H05 TFA (6H05 trifluoroacetate) is a selective, and allosteric oncogenic mutant K-Ras(G12C) inhibitor.Formula:C22H31ClF3N3O4S3Purezza:98.83%Colore e forma:SolidPeso molecolare:590.14Ref: TM-T7326
1mg65,00€2mg90,00€5mg127,00€1mL*10mM (DMSO)166,00€10mg217,00€25mg358,00€50mg538,00€100mg765,00€CCG-1423
CAS:CCG-1423, a selective RhoA pathway inhibitor, suppresses SRF-mediated transcription.Formula:C18H13ClF6N2O3Purezza:99.80%Colore e forma:SolidPeso molecolare:454.75Ref: TM-T2014
5mg35,00€1mL*10mM (DMSO)40,00€10mg54,00€25mg90,00€50mg154,00€100mg248,00€200mg385,00€500mg625,00€ASP2453
CAS:ASP2453 is a potent, selective and covalent inhibitor of KRAS G12C.Formula:C40H48F3N7O4Purezza:99.71%Colore e forma:SolidPeso molecolare:747.85ERK-IN-3
CAS:ERK-IN-3 (ASN007 free base) is a potent and orally active inhibitor of ERK.Formula:C22H25ClFN7O2Purezza:99.76% - 99.81%Colore e forma:White SolidPeso molecolare:473.93CCG-203971
CAS:CCG-203971 is an inhibitor of SRE activation in the prostate cancer cell line PC-3 (IC50: 6.4 μM), with 87% inhibition of SRE activation achieved at 100 μM.Formula:C23H21ClN2O3Purezza:98.82% - 99.50%Colore e forma:SolidPeso molecolare:408.88EHT 1864 2HCl
CAS:EHT 1864 (EHT 1864 2HCl) is a Rac family GTPase inhibitor that blocks activation by direct binding to Rac1, Rac1b, Rac2, and Rac3. Cost effective and quality assured.Formula:C25H29Cl2F3N2O4SPurezza:98.39% - 99.42%Colore e forma:SolidPeso molecolare:581.47CASIN
CAS:CASIN (Pirl1-related Compound 2) is a specific inhibitor of GTPase Cdc42 (IC50: 2 uM).Formula:C20H22N2OPurezza:98.18% - >99.99%Colore e forma:SolidPeso molecolare:306.4Ref: TM-T3971
1mg35,00€2mg50,00€5mg71,00€1mL*10mM (DMSO)71,00€10mg114,00€25mg178,00€50mg268,00€100mg413,00€500mg888,00€K-Ras(G12C) inhibitor 6
CAS:Irreversible K-Ras(G12C) inhibitor 6 fully modifies the protein at 10 μM after 24h in vitro.Formula:C17H22Cl2N2O3SPurezza:89.07% - 97.09%Colore e forma:SolidPeso molecolare:405.33Atranorin
CAS:Atranorin has antinociceptive, anti-inflammatory, can be pro-oxidant or antioxidant, and protects cells from H(2)O(2)-induced oxidative stress.Formula:C19H18O8Purezza:98.76% - 99.57%Colore e forma:White SolidPeso molecolare:374.34K-Ras(G12C) inhibitor 9
CAS:K-Ras(G12C) inhibitor 9 is an allosteric inhibitor of oncogenic K-Ras(G12C).Formula:C16H21ClIN3O4SPurezza:97.33% - 97.45%Colore e forma:SolidPeso molecolare:513.78Ref: TM-T6556
1mg34,00€5mg78,00€10mg108,00€1mL*10mM (DMSO)108,00€25mg215,00€50mg311,00€100mg425,00€200mg597,00€RBC8
CAS:RBC8 is a specific GTPases RalA/RalB inhibitor by inhibiting the binding of Ral to its effector RALBP1, no inhibition on the GTPases RhoA and Ras.Formula:C25H20N4O3Purezza:98.44% - 99.81%Colore e forma:White SolidPeso molecolare:424.45Ref: TM-T6634
1mg46,00€1mL*10mM (DMSO)92,00€5mg96,00€10mg147,00€25mg281,00€50mg447,00€100mg650,00€200mg888,00€(Rac)-Antineoplaston A10
CAS:Antineoplaston A10 is the first identified human antineoplaston, naturally occurring with anti-proliferative properties.Formula:C13H14N2O3Purezza:98.41%Colore e forma:White SolidPeso molecolare:246.26K-Ras(G12C) inhibitor 12
CAS:K-Ras(G12C) inhibitor 12 is an allosteric inhibitor of oncogenic K-Ras(G12C).Formula:C15H17ClIN3O3Purezza:97.16%Colore e forma:SolidPeso molecolare:449.67(S)-AMG-510
CAS:(S)-AMG-510 is the S-type compound of AMG-510 (Sotorasib), which effectively and selectively inhibits KRASG12C.Cost-effective and quality-assured.Formula:C30H30F2N6O3Purezza:99.05% - 99.76%Colore e forma:SolidPeso molecolare:560.594Ref: TM-T22258
2mg34,00€5mg50,00€1mL*10mM (DMSO)73,00€10mg80,00€25mg147,00€50mg259,00€100mg404,00€500mg888,00€CCG-100602
CAS:CCG-100602 inhibits RhoA/C-mediated, SRF-driven luciferase expression in PC-3 prostate cancer cells (IC50 :9.8 μM).Formula:C21H17ClF6N2O2Purezza:99.58%Colore e forma:SolidPeso molecolare:478.82Ref: TM-T22062
5mg35,00€1mL*10mM (DMSO)40,00€10mg54,00€25mg108,00€50mg178,00€100mg286,00€200mg425,00€Adagrasib
CAS:View and buy Adagrasib (MRTX849) from TargetMol.MRTX849 is a potent, selective and covalent KRASG12C inhibitor with potential antineoplastic activity. Cited in 2 publications.Formula:C32H35ClFN7O2Purezza:99.10% - 99.9%Colore e forma:SolidPeso molecolare:604.12
