Ras
Le proteine Ras sono piccole GTPasi che agiscono come interruttori molecolari nella via di segnalazione MAPK, controllando la crescita, la differenziazione e la sopravvivenza cellulare. Ras attivato avvia una cascata di segnalazione che include Raf, MEK ed ERK, portando a varie risposte cellulari. Le mutazioni nei geni Ras sono comuni nei tumori, rendendo Ras un importante focus della ricerca sul cancro. Presso CymitQuimica, offriamo una gamma di modulatori di Ras per supportare la tua ricerca in biologia del cancro, trasduzione del segnale e sviluppo terapeutico.
Trovati 156 prodotti di "Ras"
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Antineoplaston A10
CAS:Antineoplaston A10 (NSC-648539) is a Ras inhibitor potentially for the treatment of glioma, lymphoma, astrocytoma and breast cancer.Formula:C13H14N2O3Purezza:99.42%Colore e forma:SolidPeso molecolare:246.26Phellodendrine chloride
CAS:Phellodendrine chloride combats kidney inflammation by blocking macrophage and T cell activity in glomeruli.Formula:C20H24ClNO4Purezza:98.85% - 99.05%Colore e forma:SolidPeso molecolare:377.86Y16
CAS:Y16 is a G protein-coupled Rho GEFs inhibitor and also a specific inhibitor of LARG with a Kd of 76 nM.Cost-effective and quality-assured.Formula:C24H20N2O3Purezza:98.26% - 99.85%Colore e forma:SolidPeso molecolare:384.43NSC 23766 trihydrochloride
CAS:NSC 23766 trihydrochloride (Rac1 Inhibitor) is an inhibitor of Rac GTPase targeting Rac activation by GEFs; no inhibitory for RhoA or Cdc42.Formula:C24H35N7·3HClPurezza:96.48% - 99.54%Colore e forma:SolidPeso molecolare:530.96CID-1067700
CAS:CID-1067700 is one of the first identified competitive inhibitors of nucleotide binding by Ras-related GTPases（Rab7 with a Ki of 13 nM).Formula:C18H18N2O4S2Purezza:99.46%Colore e forma:SolidPeso molecolare:390.48Kobe0065
CAS:<p>Kobe0065: novel small-molecule, inhibits Ras–Raf, Ki=46±13 μM, blocks H-Ras·GTP/c-Raf-1 RBD binding.</p>Formula:C15H11ClF3N5O4SPurezza:98% - >99.99%Colore e forma:SolidPeso molecolare:449.79EHT 1864 2HCl
CAS:EHT 1864 (EHT 1864 2HCl) is a Rac family GTPase inhibitor that blocks activation by direct binding to Rac1, Rac1b, Rac2, and Rac3. Cost effective and quality assured.Formula:C25H29Cl2F3N2O4SPurezza:98.39% - 99.42%Colore e forma:SolidPeso molecolare:581.47CASIN
CAS:CASIN (Pirl1-related Compound 2) is a specific inhibitor of GTPase Cdc42 (IC50: 2 uM).Formula:C20H22N2OPurezza:98.18% - >99.99%Colore e forma:SolidPeso molecolare:306.4Atranorin
CAS:Atranorin has antinociceptive, anti-inflammatory, can be pro-oxidant or antioxidant, and protects cells from H(2)O(2)-induced oxidative stress.Formula:C19H18O8Purezza:98.76% - 99.57%Colore e forma:SolidPeso molecolare:374.34MLS-573151
CAS:<p>MLS-573151 is a selective inhibitor of GTPase Cdc42(EC50 of 2 μM).</p>Formula:C21H19N3O2SPurezza:98.80%Colore e forma:SolidPeso molecolare:377.46Rasarfin
CAS:Rasarfin inhibits Ras and ARF6.Formula:C23H24ClN3O3Purezza:97.98%Colore e forma:SolidPeso molecolare:425.91CCG-222740
CAS:CCG-222740 is an inhibitor of Rho/MRTF pathwayFormula:C23H19ClF2N2O3Purezza:98.76%Colore e forma:SolidPeso molecolare:444.86Salirasib
CAS:Salirasib: Competitive PPMTase inhibitor, blocks Ras methylation, potential cancer treatment, Ki=2.6 μM.Formula:C22H30O2SPurezza:99.45%Colore e forma:SolidPeso molecolare:358.54ARS-1620
CAS:<p>ARS-1620 is a covalent inhibitor of K-RASG12C.</p>Formula:C21H17ClF2N4O2Purezza:98.86%Colore e forma:SolidPeso molecolare:430.84Kobe2602
CAS:Kobe 2602 is an inhibitor of Ras that exhibits anticancer chemotherapeutic activities.Formula:C14H9F4N5O4SPurezza:98.36% - 99.39%Colore e forma:SolidPeso molecolare:419.31Arglabin
CAS:Arglabin ((+)-Arglabin) is a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor, has anti-atherogenic and anticancer effects.Formula:C15H18O3Purezza:98.97% - 99.62%Colore e forma:SolidPeso molecolare:246.3BQU57
CAS:BQU57 shows selective inhibition for Ral relative to Ras or Rho and inhibit xenograft tumor growth.Formula:C16H13F3N4OPurezza:97.45% - 98.72%Colore e forma:SolidPeso molecolare:334.3Sotorasib
CAS:<p>Sotorasib (AMG-510) is an orally active and selective covalent inhibitor of KRAS G12C.</p>Formula:C30H30F2N6O3Purezza:98% - 99.95%Colore e forma:SolidPeso molecolare:560.594ML141
CAS:ML141 (CID-2950007) is an effective, specific and reversible non-competitive inhibitor of Rho family GTPase cdc42 (IC50: 200 nM).Formula:C22H21N3O3SPurezza:99.36% - 99.56%Colore e forma:SolidPeso molecolare:407.49KRAS inhibitor-9
CAS:KRAS inhibitor-9 (DUN09716) hinders GTP-KRAS formation, with a Kd of 92 μM, causes G2/M arrest, and induces apoptosis in mutated NSC-LC cells.Formula:C13H9ClN2S2Purezza:99.66%Colore e forma:SolidPeso molecolare:292.81
