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Ras

Ras

Le proteine Ras sono piccole GTPasi che agiscono come interruttori molecolari nella via di segnalazione MAPK, controllando la crescita, la differenziazione e la sopravvivenza cellulare. Ras attivato avvia una cascata di segnalazione che include Raf, MEK ed ERK, portando a varie risposte cellulari. Le mutazioni nei geni Ras sono comuni nei tumori, rendendo Ras un importante focus della ricerca sul cancro. Presso CymitQuimica, offriamo una gamma di modulatori di Ras per supportare la tua ricerca in biologia del cancro, trasduzione del segnale e sviluppo terapeutico.

Trovati 156 prodotti di "Ras"

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  • pan-KRAS-IN-17
    Targetmol
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    pan-KRAS-IN-17

    CAS:
    <p>pan-KRAS-IN-17 (Example 34) is an inhibitor that targets multiple forms of the KRAS protein.</p>
    Formula:C34H33F3N5O8P
    Colore e forma:Solid
    Peso molecolare:727.623

    Ref: TM-T205570

  • SOS2 ligand 1
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    SOS2 ligand 1

    CAS:
    SOS2 ligand 1 (compound 2) is a selective ligand for son of sevenless 2 (SOS2), exhibiting a KD value of 4.6 µM.
    Formula:C19H21N5O
    Colore e forma:Solid
    Peso molecolare:335.403

    Ref: TM-T204872

  • INCB159020
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    INCB159020

    CAS:
    INCB159020 is an orally active inhibitor of KRAS G12D, exhibiting a KRAS G12D SPR value of 2.2 nM. It demonstrates anti-tumor activity.
    Formula:C37H35ClFN7O2
    Colore e forma:Solid
    Peso molecolare:664.171

    Ref: TM-T204240

  • KRas G12C inhibitor 2
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    KRas G12C inhibitor 2

    CAS:
    <p>KRas G12C inhibitor 2 is a compound that inhibits KRas G12C.</p>
    Formula:C32H37N7O3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:567.68

    Ref: TM-T11777

  • KRAS inhibitor-8
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    KRAS inhibitor-8

    CAS:
    KRAS inhibitor-8 is a potent KRAS G12C inhibitor.
    Formula:C26H24ClF4N5O3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:565.95

    Ref: TM-T11775

  • KRAS G12D inhibitor 28
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    KRAS G12D inhibitor 28

    CAS:
    <p>KRAS G12D inhibitor 28 (Compound 1) is an inhibitor of KRAS G12D and can be utilized in cancer research.</p>
    Formula:C35H32Cl2FN5O
    Colore e forma:Solid
    Peso molecolare:628.57

    Ref: TM-T207473

  • KRAS inhibitor-41
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    KRAS inhibitor-41

    CAS:
    <p>KRAS inhibitor-41 is a KRAS inhibitor with an IC50 value of less than 0.01 μM for both KRAS G12D and KRAS G12V mutations. It effectively inhibits RAS mutant cell lines GP2D (KRAS-G12D) and SW620 (KRAS-G12V). KRAS inhibitor-41 is applicable for cancer research.</p>
    Formula:C30H37FN10OS
    Colore e forma:Solid
    Peso molecolare:604.745

    Ref: TM-T206791

  • Sosimerasib
    Targetmol
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    Sosimerasib

    CAS:
    <p>Sosimerasib is an inhibitor of the kirsten rat sarcoma viral oncogene homolog (KRAS) and exhibits antitumor activity.</p>
    Formula:C36H39ClFN7O4
    Colore e forma:Solid
    Peso molecolare:688.191

    Ref: TM-T206171

  • pan-KRAS degrader 1
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    pan-KRAS degrader 1

    CAS:
    <p>Pan-KRAS degrader 1 (Compound 1) is a broad-spectrum KRAS degrader, exhibiting an inhibitory constant Ki value of 25 nM against KRASG12V as determined by surface plasmon resonance (SPR). Additionally, this compound demonstrates antitumor activity.</p>
    Formula:C22H26N8OS
    Colore e forma:Solid
    Peso molecolare:450.56

    Ref: TM-T200566

  • Rho GTPase inhibitor 1
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    Rho GTPase inhibitor 1

    CAS:
    Rho GTPase inhibitor 1 (compound 7) is a potent inhibitor of Rho GTPase. It exhibits high affinity for Cdc42, Rac1, and RhoA, with dissociation constants (KDs) of 151 μM, 352 μM, and 232 μM, respectively. Additionally, Rho GTPase inhibitor 1 reduces cell migration in glioblastoma cell lines.
    Formula:C18H16N2O
    Colore e forma:Solid
    Peso molecolare:276.33

    Ref: TM-T207196

  • (+)-Perillyl alcohol
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    (+)-Perillyl alcohol

    CAS:
    (+)-Perillyl alcohol (0.25-1 mM) inhibits cell growth in SW480 cells. At a concentration of 1 mM and a duration of 24 hours, (+)-Perillyl alcohol increases the number of cells in the G0/G1 phase and reduces the number in the S phase in SW480 cells.
    Formula:C10H16O
    Colore e forma:Solid
    Peso molecolare:152.23

    Ref: TM-T88792

  • ADT-1004
    Targetmol
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    ADT-1004

    CAS:
    ADT-1004 is an inhibitor of RAS. It can be used for research involving Ras-mediated diseases.
    Formula:C33H36FN3O6
    Colore e forma:Soild
    Peso molecolare:589.65

    Ref: TM-T210541

  • KRAS G12C inhibitor 15
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    KRAS G12C inhibitor 15

    CAS:
    <p>KRAS G12C inhibitor 15 is a potent KRAS G12C inhibitor .</p>
    Formula:C25H21ClF2N4O3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:498.91

    Ref: TM-T11769

  • KRAS inhibitor-34
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    KRAS inhibitor-34

    CAS:
    KRAS inhibitor-34 (compound 27) is a KRAS inhibitor with an IC50 of 6.4 nM and is utilized in oncological research.
    Formula:C43H41F3N6O3
    Colore e forma:Solid
    Peso molecolare:746.82

    Ref: TM-T200670

  • RGT-018
    Targetmol
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    RGT-018

    CAS:
    RGT-018 is a potent oral SOS1 inhibitor with antitumor properties. It exerts its anticancer activity by inhibiting KRAS activation, thereby hindering cancer cell proliferation.
    Formula:C27H24F3N7O2
    Colore e forma:Solid
    Peso molecolare:535.52

    Ref: TM-T89897

  • BMS-214662
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    BMS-214662

    CAS:
    BMS-214662 is a selective farnesyl transferase inhibitor with anti-tumor activity, used in research on pancreatic cancer, head and neck cancer, and lung cancer.
    Formula:C25H23N5O2S2
    Purezza:99.58% - 99.58%
    Colore e forma:Solid
    Peso molecolare:489.61

    Ref: TM-T10567