Ras
Le proteine Ras sono piccole GTPasi che agiscono come interruttori molecolari nella via di segnalazione MAPK, controllando la crescita, la differenziazione e la sopravvivenza cellulare. Ras attivato avvia una cascata di segnalazione che include Raf, MEK ed ERK, portando a varie risposte cellulari. Le mutazioni nei geni Ras sono comuni nei tumori, rendendo Ras un importante focus della ricerca sul cancro. Presso CymitQuimica, offriamo una gamma di modulatori di Ras per supportare la tua ricerca in biologia del cancro, trasduzione del segnale e sviluppo terapeutico.
Trovati 167 prodotti per "Ras".
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KRAS G12D modulator-1
CAS:KRAS G12D modulator-1 (compound 6), a potent modulator of KRAS G12D, exhibits IC50 values ranging from 1-10 μM against NEA-G12D, PPI-G12D, and p ERK-AGS, and isFormula:C30H36FN5O4Purezza:98%Colore e forma:SolidPeso molecolare:549.64pan-KRAS-IN-3
CAS:Pan-KRAS-IN-3 (Example 84) is a pan-KRAS inhibitor suitable for cancer research [1].Formula:C33H32F3N5O2Purezza:98%Colore e forma:SolidPeso molecolare:587.63TH-Z827
CAS:TH-Z827 is a mutant-selective inhibitor targeting KRAS(G12D) with an IC50 of 2.4 μM, demonstrating specificity by not binding to KRAS(WT) or KRAS(G12C).Formula:C30H38N6OPurezza:98%Colore e forma:SolidPeso molecolare:498.66KRAS G12C inhibitor 5
CAS:KRAS G12C inhibitor 5 is a KRas G12C inhibitor.Formula:C32H37N7O2Purezza:98%Colore e forma:SolidPeso molecolare:551.68CCG-232964
CAS:CCG-232964 is an orally active Rho/MRTF/SRF inhibitor that suppresses LPA-induced CTGF gene expression [1].Formula:C15H15ClN2O3SPurezza:98%Colore e forma:SolidPeso molecolare:338.81XRP44X
CAS:XRP44X (XRP 44X) is a potent inhibitor of Ras-Net (Elk-3) pathway.Formula:C21H21ClN4OPurezza:99.67%Colore e forma:SolidPeso molecolare:380.87KRAS G12C inhibitor 59
CAS:KRAS G12C Inhibitor 59 is a compound with anticancer properties.Formula:C32H39F6N7O5Purezza:98%Colore e forma:SolidPeso molecolare:715.69RBC10
CAS:RBC10 inhibits the binding of Ral to its effector RALBP1, as well as inhibiting Ral-mediated cell spreading of murine embryonic fibroblasts and anchorage-Formula:C24H25ClN2O2Purezza:99.71%Colore e forma:White SolidPeso molecolare:408.92KRAS G12C inhibitor 14
CAS:KRAS G12C inhibitor 14 is a potent KRAS G12C inhibitor with an IC 50 of 18 nM [1].Formula:C24H19ClF2N4O3Purezza:98%Colore e forma:SolidPeso molecolare:484.88KRAS G12C inhibitor 17
CAS:KRAS G12C inhibitor 17 is a potent KRAS G12C inhibitor.Formula:C24H20ClF2N3O3Purezza:98%Colore e forma:SolidPeso molecolare:471.88ML-099
CAS:ML-099 is a pan Ras-related GTPases activator that activates Rac1, Ras, GTP-binding protein (Rab7), Rab2A and cell division cycle 42.Formula:C14H13NO2SPurezza:99.73%Colore e forma:SolidPeso molecolare:259.32Ref: TM-T22991
1mg46,00€2mg60,00€1mL*10mM (DMSO)88,00€5mg90,00€10mg144,00€25mg289,00€50mg462,00€100mg672,00€PROTAC KRAS G12C degrader-3
CAS:PROTAC KRAS G12C Degrader-3 (Comp 283) serves as a potent degrader of KRAS G12C, utilized in cancer research [1].Formula:C63H75ClN14O6Purezza:98%Colore e forma:SolidPeso molecolare:1159.81KRas G12C inhibitor 1
CAS:KRas G12C inhibitor 1 is a compound that inhibits KRas G12C.Formula:C31H38N6O3Purezza:98%Colore e forma:SolidPeso molecolare:542.67KRAS G12C inhibitor 13
CAS:KRAS G12C inhibitor 13 is a KRAS G12C inhibitor .Formula:C40H46F3N7O4Purezza:98%Colore e forma:SolidPeso molecolare:745.83BDP9066
CAS:BDP9066 is a potent and selective MRCK inhibitor, inhibits MRCKβ and MRCKα/β, and can be used for the prevention and treatment of skin cancer.Formula:C20H24N6Purezza:98.18%Colore e forma:White SolidPeso molecolare:348.44Ref: TM-T14521
1mg54,00€5mg114,00€1mL*10mM (DMSO)126,00€10mg178,00€25mg409,00€50mg708,00€100mg1.224,00€Pan-RAS-IN-1
CAS:Pan-RAS-IN-1 is an inhibitor of pan-Ras. It disrupts the interaction of Ras proteins and their effectors.Formula:C36H41Cl2F3N6O2Purezza:99.77%Colore e forma:SolidPeso molecolare:717.65Ref: TM-T16432
1mg75,00€2mg92,00€5mg137,00€10mg205,00€1mL*10mM (DMSO)210,00€25mg416,00€50mg625,00€100mg888,00€500mg1.783,00€Rho GTPase inhibitor 1
CAS:Rho GTPase inhibitor 1 (compound 7) is a potent inhibitor of Rho GTPase. It exhibits high affinity for Cdc42, Rac1, and RhoA, with dissociation constants (KDs) of 151 μM, 352 μM, and 232 μM, respectively. Additionally, Rho GTPase inhibitor 1 reduces cell migration in glioblastoma cell lines.Formula:C18H16N2OColore e forma:SolidPeso molecolare:276.33ADT-1004
CAS:ADT-1004 is a small-molecule RAS inhibitor that suppresses the growth of mutant RAS tumor cells by blocking RAS-mediated signaling pathways.Formula:C33H36FN3O6Purezza:99.04%Colore e forma:Yellow SolidPeso molecolare:589.65Dorrigocin A
CAS:Dorrigocin A, an analog of Migrastatin, inhibits the carboxymethyltransferase involved in Ras processing, reversing the morphology of Ras-transformed NIH/3T3 cells. Dorrigocin A holds potential for research as an anticancer and anti-arthritis agent.Formula:C27H41NO8Colore e forma:SolidPeso molecolare:507.616ZCL279
CAS:ZCL279 is a small molecule modulator (SMM) that inhibits the interaction between CDC42 and intersectin (ITSN). At lower concentrations (<10 μM), ZCL279 activates Cdc42, a cytoplasmic small GTPase in the Ras superfamily, while at higher concentrations (<10 μM) it significantly inhibits it.Formula:C24H18N2O7S2Colore e forma:SolidPeso molecolare:510.539
