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ERK

ERK

ERK è una proteina chiave nella via di segnalazione MAPK (Mitogen-Activated Protein Kinase), coinvolta nella trasmissione dei segnali dai recettori di superficie cellulare al DNA nel nucleo della cellula. ERK svolge un ruolo cruciale nella regolazione di vari processi cellulari, tra cui la proliferazione, la differenziazione e la sopravvivenza. La disregolazione della segnalazione ERK è associata allo sviluppo del cancro e di altre malattie, rendendola un importante bersaglio per l'intervento terapeutico. Presso CymitQuimica, offriamo una selezione di inibitori e modulatori di ERK di alta qualità per supportare la tua ricerca sulla segnalazione cellulare, oncologia e sviluppo terapeutico.

Trovati 204 prodotti di "ERK"

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  • Tenuifoliside A
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    Tenuifoliside A

    CAS:
    Tenuifoliside A has anti-apoptotic , neuroprotective activity.
    Formula:C31H38O17
    Purezza:98.99% - 99.91%
    Colore e forma:Solid
    Peso molecolare:682.62

    Ref: TM-T3856

  • BAY885
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    BAY885

    CAS:
    BAY885 is a new ERK5 inhibitor.
    Formula:C25H28F3N7O2
    Purezza:99.83%
    Colore e forma:Solid
    Peso molecolare:515.53

    Ref: TM-T10479

  • Mogrol
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    Mogrol

    CAS:
    Mogrol, a biometabolite of mogrosides, functions by inhibiting the ERK1/2 and STAT3 pathways, diminishing CREB activation, and activating AMPK signaling.
    Formula:C30H52O4
    Purezza:99.85% - 99.90%
    Colore e forma:Solid
    Peso molecolare:476.73

    Ref: TM-TN2346

  • Temuterkib
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    Temuterkib

    CAS:
    <p>LY3214996 (Temuterkib) is a potent oral ERK1/2 inhibitor with potential cancer-fighting properties.</p>
    Formula:C22H27N7O2S
    Purezza:99.57% - >99.99%
    Colore e forma:Solid
    Peso molecolare:453.56

    Ref: TM-T4091

  • ERK5-IN-1
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    ERK5-IN-1

    CAS:
    ERK5-IN-1 is a potent ERK5 inhibitor (IC50: 87 nM). It also inhibits LRRK2[G2019S] (IC50: 26 nM).
    Formula:C25H29N7O2
    Purezza:97.70%
    Colore e forma:Solid
    Peso molecolare:459.54

    Ref: TM-T5184

  • Tauroursodeoxycholate
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    Tauroursodeoxycholate

    CAS:
    Tauroursodeoxycholate (UR 906), a hydrophilic bile acid, low in humans, may treat PBC, insulin resistance, and ALS.
    Formula:C26H45NO6S
    Purezza:98.77% - 99.93%
    Colore e forma:White Solid
    Peso molecolare:499.7

    Ref: TM-T2532

  • Loureirin B
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    Loureirin B

    CAS:
    Loureirin B suppresses fibrosis by modulating MMPs/TIMPs, hindering fibroblast growth, and targeting TGF-β1/Smad2/3 pathway.
    Formula:C18H20O5
    Purezza:99.33% - 99.86%
    Colore e forma:Solid
    Peso molecolare:316.35

    Ref: TM-T3876

  • UNC569
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    UNC569

    CAS:
    UNC569 selectively inhibits kidney URAT1, regulating uric acid excretion and aiding gout patient's uric balance.
    Formula:C22H29FN6
    Purezza:98.91% - 99.67%
    Colore e forma:Solid
    Peso molecolare:396.5

    Ref: TM-T21302

  • DEL-22379
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    DEL-22379

    CAS:
    DEL-22379 is a water-soluble ERK dimerization inhibitor with IC50 of ～0.5 μM.
    Formula:C26H28N4O3
    Purezza:99.3% - 99.53%
    Colore e forma:Solid
    Peso molecolare:444.53

    Ref: TM-T6818

  • 2,5-Dihydroxyacetophenone
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    2,5-Dihydroxyacetophenone

    CAS:
    2,5-Dihydroxyacetophenone has anti-anxiety, neuroprotective, anti-inflammatory properties, and modulates cell signaling and melanogenesis.
    Formula:C8H8O3
    Purezza:99.75%
    Colore e forma:Yellow Powder
    Peso molecolare:152.15

    Ref: TM-TCS2170

  • Butein
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    Butein

    CAS:
    Butein is a cAMP-specific PDE inhibitor, protein tyrosine kinase inhibitor, and SIRT1 activator.Cost-effective and quality-assured.
    Formula:C15H12O5
    Purezza:98.76% - >99.99%
    Colore e forma:Solid
    Peso molecolare:272.25

    Ref: TM-T6427

  • Pachymic acid
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    Pachymic acid

    CAS:
    Pachymic acid (3-O-Acetyltumulosic acid) is a natural product, and inhibits Akt and ERK signaling pathways.
    Formula:C33H52O5
    Purezza:99.43% - >99.99%
    Colore e forma:White Powder
    Peso molecolare:528.76

    Ref: TM-T6S0619

  • β-Neoendorphin acetate(77739-21-0 free base)
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    β-Neoendorphin acetate(77739-21-0 free base)

    CAS:
    <p>beta-Neoendorphin acetate is an agonist of κ-opioid receptor</p>
    Formula:C56H81N13O14
    Purezza:99.91%
    Colore e forma:Solid
    Peso molecolare:1160.34

    Ref: TM-TP2322L

  • GRK5-IN-2
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    GRK5-IN-2

    CAS:
    GRK5-IN-2, a pyridine-based bicyclic compound, is a potent G-protein-coupled receptor kinase 5 (GRK5) inhibitor.
    Formula:C20H20N4O4
    Purezza:99.92%
    Colore e forma:Solid
    Peso molecolare:380.4

    Ref: TM-T9609

  • 6-OAU
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    6-OAU

    CAS:
    6-OAU is a GPR84 agonist, activates it in HEK293 cells with a 105 nM EC50.
    Formula:C12H21N3O2
    Purezza:98.14% - 99.01%
    Colore e forma:Solid
    Peso molecolare:239.31

    Ref: TM-T2036

  • Nitidine chloride
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    Nitidine chloride

    CAS:
    1.
    Formula:C21H18ClNO4
    Purezza:96.59% - 99.55%
    Colore e forma:Solid
    Peso molecolare:383.82

    Ref: TM-T5S0761

  • XMD17-109
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    XMD17-109

    CAS:
    <p>XMD17-109 (ERK5-IN-1) is a new selective ERK-5 inhibitor (EC50: 4.2 uM, HEK293 cells).</p>
    Formula:C36H46N8O3
    Purezza:98.75% - 99.7%
    Colore e forma:Solid
    Peso molecolare:638.8

    Ref: TM-T1842

  • DCLK1-IN-1
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    DCLK1-IN-1

    CAS:
    <p>DCLK1-IN-1 is a selective, in vivo compatible chemical probe of the kinase domain of doublecortin-like kinase 1 (DCLK1).Cost-effective and quality-assured.</p>
    Formula:C26H28F3N7O2
    Purezza:98.55% - 99.28%
    Colore e forma:Solid
    Peso molecolare:527.54

    Ref: TM-T8418

  • AG126
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    AG126

    CAS:
    AG126 (Tyrphostin AG126) selectively inhibits the phosphorylation of ERK1 (p44) and ERK2 (p42). AG-126 weakly inhibits epidermal GFRK and platelet-derived GFRK.
    Formula:C10H5N3O3
    Purezza:97.35%
    Colore e forma:Solid
    Peso molecolare:215.16

    Ref: TM-T4092

  • ASP2453
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    ASP2453

    CAS:
    ASP2453 is a potent, selective and covalent inhibitor of KRAS G12C.
    Formula:C40H48F3N7O4
    Purezza:99.71%
    Colore e forma:Solid
    Peso molecolare:747.85

    Ref: TM-T39738