p38 MAPK
Le p38 MAPK sono un sottogruppo di MAPK che rispondono ai segnali di stress e sono coinvolte nella regolazione dell'infiammazione, della differenziazione cellulare, dell'apoptosi e dell'autofagia. La segnalazione delle p38 MAPK è cruciale nelle risposte immunitarie ed è implicata in varie malattie, tra cui condizioni infiammatorie croniche, cancro e disturbi neurodegenerativi. Presso CymitQuimica, offriamo una gamma completa di inibitori e modulatori delle p38 MAPK per supportare la tua ricerca sull'infiammazione, la risposta allo stress e lo sviluppo terapeutico.
Trovati 117 prodotti di "p38 MAPK"
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BMS582949
CAS:<p>BMS-582949 inhibits p38 MAPK with 13 nM IC50, blocking kinase activity and activation.</p>Formula:C22H26N6O2Purezza:98.11%Colore e forma:SolidPeso molecolare:406.48Pexmetinib
CAS:<p>Pexmetinib (ARRY-614) is an orally bioavailable dual p38 MAPK/Tie-2 inhibitor.Cost-effective and quality-assured.</p>Formula:C31H33FN6O3Purezza:99.07% - 99.66%Colore e forma:SolidPeso molecolare:556.63Dehydrocorydaline nitrate
CAS:<p>DHC curbs antibody and cell-mediated allergies, inhibits mitochondrial potential in macrophages, and has antinociceptive, anti-inflammatory effects.</p>Formula:C22H24N2O7Purezza:99.79% - 99.92%Colore e forma:SolidPeso molecolare:428.44VX-702
CAS:<p>VX-702: selective p38α MAPK inhibitor, potent anti-cytokine for rheumatoid arthritis.</p>Formula:C19H12F4N4O2Purezza:99% - >99.99%Colore e forma:SolidPeso molecolare:404.32TLC1566-0618
CAS:<p>TLC1566-0618 shows antitumor activity and targets stat.</p>Formula:C20H15NO3S3Purezza:98%Colore e forma:SolidPeso molecolare:413.53(S)-(-)-PH-797804
CAS:Prodotto controllatoFormula:C19H38N5O5Colore e forma:NeatPeso molecolare:416.536LY 294002 Hydrochloride
CAS:Prodotto controllato<p>Applications LY 294002 Hydrochloride is a highly selective inhibitor of Phosphatidylinositol 3-kinase (PI3K). It is a salt analogue of LY 294002 (L486590).<br>References Lin, C., et. al.: J. Biol. Chem., 286, 10483 (2011); Cao, H., et. al.: J. Biol. Chem., 288, 30399 (2013);<br></p>Formula:C19H17NO3·(HCl)Colore e forma:NeatPeso molecolare:343.8SB 706504
CAS:<p>SB 706504 is an effective p38 MAPK inhibitor that suppresses inflammatory gene expression in macrophages and inhibits TNFα production in COPD.</p>Formula:C24H19F3N8OPurezza:98.686%Colore e forma:SolidPeso molecolare:492.46AL 8697
CAS:<p>AL 8697 is a selective p38α MAPK inhibitor (IC50 = 6 nM) with 14-fold selectivity over p38β (IC50 = 82 nM) and 300-fold selectivity over a panel of 91 kinases.</p>Formula:C21H21F3N4OPurezza:99.55% - 99.89%Colore e forma:SolidPeso molecolare:402.41PF-05381941
CAS:<p>PF-05381941 is a selective and potent dual inhibitor of TAK1 and p38α that inhibits the kinase activity of TAK1 by binding to its active site.</p>Formula:C27H26N6O2Purezza:98.04%Colore e forma:SolidPeso molecolare:466.53EO-1606
CAS:<p>EO-1606 is a p38MAP kinase inhibitor with anti-inflammatory activity and may be used in studies of Alzheimer;s disease and dermatitis.</p>Formula:C21H17ClFNOPurezza:98.28% - 98.84%Colore e forma:SolidPeso molecolare:353.82p38α inhibitor 4
CAS:<p>p38α inhibitor 4 is a selective MAPK p38α inhibitor, which is used to study diabetes, pain and chronic inflammation.</p>Formula:C14H7F6N3OPurezza:99.69%Colore e forma:SolidPeso molecolare:347.215UR13870
CAS:<p>UR-13870 (Org 48762-0) is a p38 MAPK inhibitor that prevents bone damage in collagen-induced arthritis in mice.</p>Formula:C24H16F2N4Purezza:99.18% - >99.99%Colore e forma:SolidPeso molecolare:398.41AKP-001
CAS:<p>AKP-001 is a selective inhibitor of MAPK of the p38α isoform and is used in the study of immune and digestive disorders.</p>Formula:C21H13ClF2N4O2Purezza:99.50% - 99.92%Colore e forma:SolidPeso molecolare:426.8p38 MAPK Inhibitor
CAS:<p>p38 MAPK inhibitor is a potent inhibitor of p38 MAP kinase (IC50 = 35 nM). It inhibits senescence induced by the oncogene RAS.</p>Formula:C20H13ClFN3OPurezza:99.91%Colore e forma:SolidPeso molecolare:365.79SB-747651A Dihydrochloride
CAS:<p>SB-747651A dihydrochloride, an MSK1 inhibitor (IC50=11 nM), also targets PRK2, RSK1, p70S6K, ROCK-II; potential in inflammation study.</p>Formula:C16H24Cl2N8OPurezza:98.05%Colore e forma:SolidPeso molecolare:415.32Org OD 02-0
CAS:<p>10-Ethenyl-19-norprogesterone (Org OD 02-0) is a selective agonist for the membrane progesterone receptor α (mPRα) with an IC50 of 33.9 nM, known to activate</p>Formula:C22H30O2Purezza:98%Colore e forma:SolidPeso molecolare:326.47p38-α MAPK-IN-1
CAS:<p>p38-α MAPK-IN-1 is a MAPK14 (p38-α) inhibitor with IC50 of 2300 nM and 5500 nM in EFC displacement assay and HTRF assay,respectively.</p>Formula:C27H35N5O3Purezza:99.93%Colore e forma:SolidPeso molecolare:477.6PLK1/p38γ-IN-1
CAS:<p>PLK1/p38γ-IN-1 (compound 14) serves as a dual inhibitor targeting both PLK1 and p38γ kinases, effectively suppressing the proliferation of human hepatocellular</p>Formula:C21H26ClN3O2Purezza:98%Colore e forma:SolidPeso molecolare:387.9
