p38 MAPK
Le p38 MAPK sono un sottogruppo di MAPK che rispondono ai segnali di stress e sono coinvolte nella regolazione dell'infiammazione, della differenziazione cellulare, dell'apoptosi e dell'autofagia. La segnalazione delle p38 MAPK è cruciale nelle risposte immunitarie ed è implicata in varie malattie, tra cui condizioni infiammatorie croniche, cancro e disturbi neurodegenerativi. Presso CymitQuimica, offriamo una gamma completa di inibitori e modulatori delle p38 MAPK per supportare la tua ricerca sull'infiammazione, la risposta allo stress e lo sviluppo terapeutico.
Trovati 112 prodotti di "p38 MAPK"
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Dehydrocorydaline nitrate
CAS:DHC curbs antibody and cell-mediated allergies, inhibits mitochondrial potential in macrophages, and has antinociceptive, anti-inflammatory effects.Formula:C22H24N2O7Purezza:99.79% - 99.92%Colore e forma:SolidPeso molecolare:428.44Ref: TM-T2S2362
1mg94,00€5mg216,00€10mg354,00€25mg582,00€50mg825,00€100mg1.111,00€200mg1.491,00€1mL*10mM (DMSO)255,00€VX-702
CAS:VX-702: selective p38α MAPK inhibitor, potent anti-cytokine for rheumatoid arthritis.Formula:C19H12F4N4O2Purezza:99% - >99.99%Colore e forma:SolidPeso molecolare:404.32TLC1566-0618
CAS:TLC1566-0618 shows antitumor activity and targets stat.Formula:C20H15NO3S3Purezza:98%Colore e forma:SolidPeso molecolare:413.53LY 294002 Hydrochloride
CAS:Prodotto controllato<p>Applications LY 294002 Hydrochloride is a highly selective inhibitor of Phosphatidylinositol 3-kinase (PI3K). It is a salt analogue of LY 294002 (L486590).<br>References Lin, C., et. al.: J. Biol. Chem., 286, 10483 (2011); Cao, H., et. al.: J. Biol. Chem., 288, 30399 (2013);<br></p>Formula:C19H17NO3·(HCl)Colore e forma:NeatPeso molecolare:343.8(S)-(-)-PH-797804
CAS:Prodotto controllatoFormula:C19H38N5O5Colore e forma:NeatPeso molecolare:416.536AL 8697
CAS:<p>AL 8697 is a selective p38α MAPK inhibitor (IC50 = 6 nM) with 14-fold selectivity over p38β (IC50 = 82 nM) and 300-fold selectivity over a panel of 91 kinases.</p>Formula:C21H21F3N4OPurezza:99.55% - 99.89%Colore e forma:SolidPeso molecolare:402.41Ref: TM-T10277
1mg70,00€5mg145,00€10mg207,00€25mg348,00€50mg495,00€100mg678,00€500mgPrezzo su richiestaSB 706504
CAS:SB 706504 is an effective p38 MAPK inhibitor that suppresses inflammatory gene expression in macrophages and inhibits TNFα production in COPD.Formula:C24H19F3N8OPurezza:98.686%Colore e forma:SolidPeso molecolare:492.46SB-747651A Dihydrochloride
CAS:SB-747651A dihydrochloride, an MSK1 inhibitor (IC50=11 nM), also targets PRK2, RSK1, p70S6K, ROCK-II; potential in inflammation study.Formula:C16H24Cl2N8OPurezza:98.05%Colore e forma:SolidPeso molecolare:415.32Ref: TM-T9652
1mg73,00€5mg155,00€10mg220,00€25mg369,00€50mg525,00€100mg712,00€500mgPrezzo su richiesta1mL*10mM (DMSO)169,00€p38 MAPK Inhibitor
CAS:p38 MAPK inhibitor is a potent inhibitor of p38 MAP kinase (IC50 = 35 nM). It inhibits senescence induced by the oncogene RAS.Formula:C20H13ClFN3OPurezza:99.91%Colore e forma:SolidPeso molecolare:365.79Ref: TM-T36010
1mg92,00€5mg279,00€10mg434,00€25mg642,00€50mg880,00€100mg1.170,00€200mg1.594,00€500µg56,00€UR13870
CAS:UR-13870 (Org 48762-0) is a p38 MAPK inhibitor that prevents bone damage in collagen-induced arthritis in mice.Formula:C24H16F2N4Purezza:99.18% - >99.99%Colore e forma:SolidPeso molecolare:398.41p38α inhibitor 4
CAS:p38α inhibitor 4 is a selective MAPK p38α inhibitor, which is used to study diabetes, pain and chronic inflammation.Formula:C14H7F6N3OPurezza:99.69%Colore e forma:SolidPeso molecolare:347.215EO-1606
CAS:EO-1606 is a p38MAP kinase inhibitor with anti-inflammatory activity and may be used in studies of Alzheimer;s disease and dermatitis.Formula:C21H17ClFNOPurezza:98.28% - 98.84%Colore e forma:SolidPeso molecolare:353.82AKP-001
CAS:AKP-001 is a selective inhibitor of MAPK of the p38α isoform and is used in the study of immune and digestive disorders.Formula:C21H13ClF2N4O2Purezza:99.50% - 99.92%Colore e forma:SolidPeso molecolare:426.8AMG-548 dihydrochloride (864249-60-5 free base)
AMG-548 dihydrochloride: oral p38α inhibitor, Ki: 0.5 nM; less so for p38β, Ki: 36 nM; >> p38γ/δ; blocks LPS-induced TNFα, IC50: 3 nM.Formula:C29H29Cl2N5OPurezza:98%Colore e forma:SolidPeso molecolare:534.48Org OD 02-0
CAS:10-Ethenyl-19-norprogesterone (Org OD 02-0) is a selective agonist for the membrane progesterone receptor α (mPRα) with an IC50 of 33.9 nM, known to activateFormula:C22H30O2Purezza:98%Colore e forma:SolidPeso molecolare:326.47p38 Kinase inhibitor 4
CAS:Compound 135, also known as p38 Kinase Inhibitor 4, is a potent inhibitor of p38 [1].Formula:C12H9Cl2N3OPurezza:98%Colore e forma:SolidPeso molecolare:282.13p38-α MAPK-IN-1
CAS:p38-α MAPK-IN-1 is a MAPK14 (p38-α) inhibitor with IC50 of 2300 nM and 5500 nM in EFC displacement assay and HTRF assay,respectively.Formula:C27H35N5O3Purezza:99.93%Colore e forma:SolidPeso molecolare:477.6Ref: TM-T12347
1mg84,00€5mg170,00€10mg266,00€25mg492,00€50mg737,00€100mg1.108,00€200mg1.485,00€1mL*10mM (DMSO)178,00€PLK1/p38γ-IN-1
CAS:PLK1/p38γ-IN-1 (compound 14) serves as a dual inhibitor targeting both PLK1 and p38γ kinases, effectively suppressing the proliferation of human hepatocellularFormula:C21H26ClN3O2Purezza:98%Colore e forma:SolidPeso molecolare:387.9AMG-548 hydrochloride (864249-60-5 free base)
AMG-548 hydrochloride is an orally active and selective p38α inhibitor (Ki: 0.5 nM) and shows slightly selective over p38β (Ki: 36 nM) and >1000 fold selectiveFormula:C29H28ClN5OPurezza:98%Colore e forma:SolidPeso molecolare:498.02
