Canale del potassio
I canali del potassio sono un gruppo diversificato di proteine di membrana che facilitano il flusso di ioni potassio (K+) attraverso la membrana cellulare. Questi canali svolgono un ruolo cruciale nel mantenimento del potenziale di membrana a riposo, nella regolazione del volume cellulare e nel controllo dell'eccitabilità dei neuroni e delle cellule muscolari. I canali del potassio sono coinvolti in vari processi fisiologici, tra cui la regolazione del ritmo cardiaco, la secrezione di insulina e il rilascio di neurotrasmettitori. La disfunzione dei canali del potassio è legata a condizioni come aritmie, epilessia e ipertensione. Presso CymitQuimica, offriamo una vasta gamma di modulatori dei canali del potassio per supportare la tua ricerca in elettrofisiologia, salute cardiovascolare e neurobiologia.
Trovati 280 prodotti di "Canale del potassio"
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AUT1
CAS:AUT1 (AUT-1) is a novel specific modulator of Kv3 channels (EC50: 4.7 and 4.9 uM for Kv3.1b and Kv3.2a).Formula:C18H19N3O4Purezza:99.8% - 99.95%Colore e forma:SolidPeso molecolare:341.36Ref: TM-T5183
1mg35,00€2mg49,00€5mg74,00€10mg106,00€25mg187,00€50mg279,00€100mg425,00€200mg615,00€1mL*10mM (DMSO)84,00€Iptakalim Hydrochloride
CAS:Iptakalim, a lipophilic para-amino compound, is a novel ATP-sensitive potassium channel (KATP) opener, as well as an α4β2-containing nicotinic acetylcholineFormula:C9H22ClNPurezza:98%Colore e forma:SolidPeso molecolare:179.731GSK369796 Dihydrochloride
CAS:GSK369796 Dihydrochloride (N-tert-butylisoquine),is an anti-malaria drug candidate.Formula:C20H24Cl3N3OPurezza:>99.99%Colore e forma:SolidPeso molecolare:428.78Ref: TM-T7195
1mg79,00€2mg101,00€5mg149,00€10mg195,00€25mg373,00€50mg562,00€100mg802,00€1mL*10mM (DMSO)145,00€PAP-1
CAS:PAP-1 (5-(4-Phenoxybutoxy)psoralen) is a selective, and orally active Kv1.3 blocker (EC50: 2 nM).Formula:C21H18O5Purezza:99.35% - 99.75%Colore e forma:White SolidPeso molecolare:350.36Ref: TM-TQ0179
2mg63,00€5mg88,00€10mg136,00€25mg291,00€50mg520,00€100mg550,00€200mg785,00€1mL*10mM (DMSO)90,00€Nigericin sodium salt
CAS:Nigericin sodium salt, an antibiotic and NLRP3 activator from S. hygroscopicus, inhibits Golgi and gram-positive bacteria, blocking viral activation.Formula:C40H67NaO11Purezza:98.2% - 99.52%Colore e forma:SolidPeso molecolare:746.94Atpenin A5
CAS:Atpenin A5 is a potent and highly specific complex II inhibitor (IC50 ~10 nM).Formula:C15H21Cl2NO5Purezza:97.33% - 99.91%Colore e forma:SolidPeso molecolare:366.24LY 303511 hydrochloride
CAS:LY 303511 hydrochloride is a potent mTOR inhibitorFormula:C19H19ClN2O2Purezza:98.47%Colore e forma:SolidPeso molecolare:342.82Mitiglinide Calcium
CAS:Mitiglinide Calcium (KAD-1229) is a blood glucose-lowering drugs, stimulating insulin secretion by closing the ATP-sensitive K+ channels in pancreatic beta-Formula:(C19H24NO3)2·CaPurezza:99.83%Colore e forma:White Crystal PosderPeso molecolare:668.88Flupirtine maleate
CAS:Flupirtine maleate (Katadolon maleate), a centrally acting non-opioid analgesia, is the salt form of Flupirtine. Flupirtine is an NMDA receptor antagonist.Formula:C15H17FN4O2·C4H4O4Purezza:99.5% - 99.9%Colore e forma:Off-White Crystalline PowderPeso molecolare:420.39Senicapoc
CAS:Senicapoc (ICA-17043) blocks Gardos channel, reduces RBC dehydration, IC50: 11 nM for rubidium flux, 30 nM for dehydration. Used in Sickle Cell therapy.Formula:C20H15F2NOPurezza:95.7% - 99.47%Colore e forma:SolidPeso molecolare:323.34E-4031 dihydrochloride
CAS:E-4031 dihydrochloride is a methanesulfonanilide class III antiarrhythmic agent that prolongs cardiac action potential duration by blocking ERG K+ channels (IC50 = 29 nM)Formula:C21H29Cl2N3O3SPurezza:99.31% - 99.87%Colore e forma:SolidPeso molecolare:474.44Allocryptopine
CAS:Allocryptopine (Thalictrimine) induces muscle contraction and relaxation in urinary bladder and ileum, respectively.Formula:C21H23NO5Purezza:99.41% - ≥95%Colore e forma:SolidPeso molecolare:369.41KS176
CAS:KS176: selective BCRP inhibitor, potent against breast cancer drug resistance; ineffective on P-gp, MRP1.Formula:C22H19N3O5Purezza:99.61% - 99.61%Colore e forma:SolidPeso molecolare:405.45-Hydroxydecanoate sodium
CAS:5-Hydroxydecanoate sodium: KATP channel blocker, IC50 ~30μM; mitochondrial substrate; antioxidant.Formula:C10H19NaO3Purezza:99.24% - 99.89%Colore e forma:SolidPeso molecolare:210.25VU0810464
CAS:VU0810464 is a non-ureaG protein-gated inwardly-rectifying potassium channels (GIRK, Kir3) activator.Formula:C18H21ClFN3OPurezza:99.62%Colore e forma:SolidPeso molecolare:349.83Ref: TM-T7899
1mg47,00€5mg95,00€10mg150,00€25mg245,00€50mg325,00€100mg434,00€200mg590,00€1mL*10mM (DMSO)104,00€Loureirin B
CAS:Loureirin B suppresses fibrosis by modulating MMPs/TIMPs, hindering fibroblast growth, and targeting TGF-β1/Smad2/3 pathway.Formula:C18H20O5Purezza:99.33% - 99.86%Colore e forma:SolidPeso molecolare:316.35Mitiglinide calcium hydrate
CAS:Mitiglinide calcium hydrate (S-21403 calcium hydrate) is a drug for the treatment of type 2 diabetes.Formula:C38H52CaN2O8Purezza:98.97% - 99.96%Colore e forma:White SolidPeso molecolare:704.91A2793
CAS:A2793 is a dual inhibitor of TWIK-associated acid-sensitive K+ channel 1 (TASK-1)/TRESK, with an IC50 for mTRESK of 6.8 μM.Formula:C13H12ClNO3Purezza:98.54%Colore e forma:SolidPeso molecolare:265.69O-Nornuciferine
CAS:O-Nornuciferine reveals distinct in vitro hERG blockages measured in HEK293 cells with the IC50 value of 2.89 uM.Formula:C18H19NO2Purezza:99.86%Colore e forma:SolidPeso molecolare:281.35ML213
CAS:ML213 (CID-3111211) is a selective activator of Kv7.2 (KCNQ2) and Kv7.4 (KCNQ4) channels, enhances Kv7.2 and Kv7.4 channels with EC50s of 230 and 510 nM,Formula:C17H23NOPurezza:>99.99%Colore e forma:SolidPeso molecolare:257.37Levcromakalim
CAS:Levcromakalim (BRL 38227) is an activator of the ATP-sensitive K+ channel.Formula:C16H18N2O3Purezza:99.74%Colore e forma:SolidPeso molecolare:286.33Ref: TM-TQ0150
1mg52,00€2mg78,00€5mg99,00€10mg150,00€25mg335,00€50mg499,00€100mg722,00€1mL*10mM (DMSO)110,00€NS 11021
CAS:NS 11021 (NS11021) , a novel opener of large-conductance Ca(2+)-activated K(+) channelsFormula:C16H9BrF6N6SPurezza:97.26%Colore e forma:SolidPeso molecolare:511.24Ref: TM-T4294
1mg44,00€5mg93,00€10mg135,00€25mg278,00€50mg472,00€100mg802,00€200mg1.074,00€1mL*10mM (DMSO)95,00€Tetraethylammonium bromide
CAS:<p>Tetraethylammonium bromide (TEA bromide) can selectively block potassium channels.</p>Formula:C8H20BrNPurezza:98%Colore e forma:White SolidPeso molecolare:210.16ML133 hydrochloride
CAS:ML133 hydrochloride (ML133 HCl) is a selective potassium channel inhibitor for Kir2.1, has no effect on Kir1.1 and weak activity for Kir4.1 and Kir7.1.Formula:C19H19NO·HClPurezza:99.48%Colore e forma:SolidPeso molecolare:313.82Ref: TM-T6592
5mg50,00€10mg66,00€25mg106,00€50mg170,00€100mg274,00€200mg354,00€500mg597,00€1mL*10mM (DMSO)52,00€SKF-96365 hydrochloride
CAS:SKF-96365 hydrochloride (SKF96365) , a SOCE inhibitor, exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal YFormula:C22H27ClN2O3Purezza:99.47% - 99.92%Colore e forma:SolidPeso molecolare:402.91Ref: TM-T2170
5mg57,00€10mg86,00€25mg138,00€50mg243,00€100mg470,00€200mg717,00€500mg1.111,00€1mL*10mM (DMSO)63,00€Rimtuzalcap
CAS:Rimtuzalcap (CAD-1883), a selective modulator for SK channels, may treat movement disorders like SCA and ET.Formula:C18H24F2N6OPurezza:99.64%Colore e forma:SolidPeso molecolare:378.42Ref: TM-T9522
1mg35,00€5mg78,00€10mg111,00€25mg215,00€50mg320,00€100mg452,00€200mg632,00€1mL*10mM (DMSO)34,00€A2764 dihydrochloride
CAS:A2764 dihydrochloride is a highly selective inhibitor of TRESK.Formula:C15H21Cl3N2OPurezza:99.05%Colore e forma:SolidPeso molecolare:351.7(±)-Naringenin
CAS:(±)-Naringenin (Naringenine) is a natural product.Formula:C15H12O5Purezza:98.06%Colore e forma:SolidPeso molecolare:272.25Dihydroberberine
CAS:Dihydroberberine has anti-atherosclerotic, anti-inflammatory, hypolipidemic and antitumor activities.Formula:C20H19NO4Purezza:93.77%Colore e forma:SolidPeso molecolare:337.37Nateglinide
CAS:Nateglinide is an oral drug for type 2 diabetes, stimulating insulin release; may cause rare acute liver injury.Formula:C19H27NO3Purezza:99.93% - 99.94%Colore e forma:White Crystalline PowderPeso molecolare:317.42Oxypeucedanin
CAS:1.Formula:C16H14O5Purezza:98.66% - 98.85%Colore e forma:SolidPeso molecolare:286.28Guanosine 5'-diphosphate
CAS:<p>Guanosine 5'-diphosphate (GDP) as Potential Iron Mobilizer, Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6/Stat-3 Pathway.</p>Formula:C10H15N5O11P2Purezza:98.46% - 99.52%Colore e forma:SolidPeso molecolare:443.2ML 297
CAS:ML 297 is a selective Kir3.1/3.2 (GIRK1/2) channel activator (IC50 values are 160, 887 and 914 nM for GIRK1/2, GIRK1/4 and GIRK1/3 respectively).Formula:C17H14F2N4OPurezza:97.85%Colore e forma:SolidPeso molecolare:328.32NS1643
CAS:NS1643 is a potent human ether-a-go-go related gene (hERG) KV11.1 channel activator with EC50 of 10.5 μM.Formula:C15H10F6N2O3Purezza:98.37% - 99.31%Colore e forma:SolidPeso molecolare:380.24GAL-021
CAS:<p>GAL-021 an intravenous BKCa-channel blocker.</p>Formula:C11H22N6OPurezza:97.71% - 99.66%Colore e forma:SolidPeso molecolare:254.33Daurisoline
CAS:Daurisoline ((R,R)-Daurisoline) is a hERG inhibitor. Daurisoline is also an autophagy blocker.Formula:C37H42N2O6Purezza:98% - 99.96%Colore e forma:Light Yellow PowderPeso molecolare:610.74NS-1619
CAS:NS1619 have cardio-protective effects after ischemia-reperfusion injury.Formula:C15H8F6N2O2Purezza:97.66% - 98%Colore e forma:SolidPeso molecolare:362.23GW9508
CAS:<p>GW9508(GW 9508) is a potent and selective agonist for FFA1 (GPR40), stimulates insulin secretion in a glucose-sensitive manner.</p>Formula:C22H21NO3Purezza:97.89% - 99.19%Colore e forma:SolidPeso molecolare:347.41JNJ 303
CAS:JNJ 303 is a potent blocker of IKs (IC50 : 64 nM).Formula:C21H29ClN2O4SPurezza:99.28%Colore e forma:SolidPeso molecolare:440.98Ref: TM-T7653
1mg48,00€2mg65,00€5mg89,00€10mg147,00€25mg325,00€50mg472,00€100mg705,00€1mL*10mM (DMSO)92,00€TRAM-34
CAS:<p>TRAM-34 (Triarylmethane-34), an effective and specific inhibitor of the intermediate-conductance Ca2+-activated K+ channel, does not block cytochrome P450.</p>Formula:C22H17ClN2Purezza:99.01% - 99.91%Colore e forma:SolidPeso molecolare:344.84ML335
CAS:ML335 is a selective activator of TREK-1 and TREK-2.Formula:C15H14Cl2N2O3SPurezza:99.73% - 99.79%Colore e forma:SolidPeso molecolare:373.25Ref: TM-T4224
2mg43,00€5mg63,00€10mg95,00€25mg187,00€50mg283,00€100mg424,00€200mg612,00€1mL*10mM (DMSO)63,00€ICA 110381
CAS:ICA 110381 is a KCNQ2/Q3 potassium channel opener for the treatment of epilepsyFormula:C12H8Cl2N2OPurezza:97.72%Colore e forma:SolidPeso molecolare:267.11Flecainide hydrochloride
CAS:Flecainide is a medication used to prevent and treat abnormally fast heart rates. This includes ventricular and supraventricular tachycardias.Formula:C17H21ClF6N2O3Purezza:97.79%Colore e forma:SolidPeso molecolare:450.81Minoxidil sulfate
CAS:Minoxidil sulfate (U-58838) is the active metabolite required to exert the vasodilatory and hair growing effects of minoxidil.Formula:C9H15N5O4SPurezza:99.01% - 99.72%Colore e forma:White Crystalline SolidPeso molecolare:289.31ASP2905
CAS:ASP-2905 is a potent and selective inhibitor of potassium channel Kv12.2 encoded by the Kcnh3/BEC1 gene.Formula:C20H17FN8Purezza:97.29% - 99.78%Colore e forma:SolidPeso molecolare:388.4Ref: TM-T9070
1mg35,00€2mg48,00€5mg70,00€10mg96,00€25mg188,00€50mg311,00€100mg512,00€1mL*10mM (DMSO)77,00€AM-92016 hydrochloride
CAS:AM-92016 is a specific blocker of rectifier potassium current.Formula:C19H24Cl2N2O4S·HClPurezza:98.68%Colore e forma:SolidPeso molecolare:483.84Ref: TM-T5585
2mg35,00€5mg52,00€10mg96,00€25mg164,00€50mg279,00€100mg399,00€200mg567,00€1mL*10mM (DMSO)58,00€NS6180
CAS:<p>NS6180 is a potent and selective KCa3.1 channel inhibitor(IC50= 9 nM). It prevents T-cell activation and inflammation.</p>Formula:C16H12F3NOSPurezza:99.83% - ≥95%Colore e forma:SolidPeso molecolare:323.33Tetraethylammonium chloride
CAS:Tetraethylammonium chloride is a quaternary ammonium compound.Formula:C8H20ClNPurezza:≥95%Colore e forma:White Solid Solid Particulate/PowderPeso molecolare:165.7RY785
CAS:RY785 is a potent and selective inhibitor of voltage-gated potassium channel such as KV2.2 (IC50 = 50 nM). RY785 may be used in pain relief studies.Formula:C21H20N4O2SPurezza:99.78%Colore e forma:SolidPeso molecolare:392.47Ref: TM-T12786
1mg51,00€5mg144,00€10mg235,00€25mg399,00€50mg560,00€100mg787,00€200mg1.093,00€1mL*10mM (DMSO)125,00€Enflurane
CAS:Enflurane (Efrane), a volatile anaesthetic, inhibits Ca2+-activated K+ channels and is used to gauge anesthesia levels in gas chromatography.Formula:C3H2ClF5OPurezza:99.64%Colore e forma:Clear Colorless Liquid Ordinary Temperature And Pressure Bp 56 8°C Density 1 50 G Cm-3 At Room Temperature Used As AnPeso molecolare:184.49
