Pompa protonica
Le pompe protoniche sono proteine di membrana che trasportano attivamente protoni (H+) attraverso la membrana cellulare o le membrane degli organelli, creando un gradiente protonico essenziale per vari processi cellulari. La pompa protonica più conosciuta è l'H+/K+ ATPasi, presente nel rivestimento dello stomaco, responsabile della secrezione acida. Le pompe protoniche sono anche fondamentali nella respirazione cellulare e nella regolazione del pH. La disfunzione dell'attività delle pompe protoniche è associata a condizioni come il reflusso acido, le ulcere e l'acidosi metabolica. Presso CymitQuimica, offriamo una selezione di inibitori e modulatori delle pompe protoniche per supportare la tua ricerca in gastroenterologia, metabolismo e bioenergetica cellulare.
Trovati 42 prodotti di "Pompa protonica"
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EN6
CAS:EN6, a small molecule, activates autophagy by modifying ATP6V1A, inhibiting mTORC1 and enhancing lysosomal function to clear TDP-43 aggregates.Formula:C19H14F2N4O2Purezza:95.74% - 97.04%Colore e forma:SolidPeso molecolare:368.34Lansoprazole
CAS:Lansoprazole (A-65006) is a 2, 2, 2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISONFormula:C16H14F3N3O2SPurezza:99.18% - 99.84%Colore e forma:White Crystalline PowderPeso molecolare:369.36Omeprazole
CAS:Omeprazole (Losec) is a proton pump inhibitor (PPI), Omeprazole(Losec) is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor.Formula:C17H19N3O3SPurezza:98.43% - 98.48%Colore e forma:White SolidPeso molecolare:345.42Omeprazole sulfide
CAS:Omeprazole sulfide (Ufiprazole), a metabolite of Omeprazole, functions as a proton pump inhibitor.Formula:C17H19N3O2SPurezza:98.83%Colore e forma:White To Slightly Collored Solid Solid CrystallinePeso molecolare:329.42Zinc pyrithione
CAS:Zinc pyrithione (OM-1563), an antibacterial and antifungal agent can disrupt membrane transport by blocking the proton pump.Formula:C10H8N2O2S2ZnPurezza:99.09% - 99.47%Colore e forma:Off-White To Tan PowderPeso molecolare:317.71Corza6 TFA
Corza6 TFA is a potent and selective peptide inhibitor of the human voltage-gated proton channel (hHv1). It binds to the external voltage-sensor domain (VSD) loop of hHv1 with a dissociation constant (Kd) of approximately 1 nM under the native hyperpolarized resting membrane potential (RMP) of mammalian cells. Additionally, Corza6 TFA induces sperm capacitation and enables continuous reactive oxygen species (ROS) production in white blood cells (WBC).Colore e forma:Odour SolidPantoprazole Sodium Hydrate
CAS:Pantoprazole Sodium Hydrate (BY1023 (sodium hydrate)) is a proton pump inhibitor drug, used for short-term treatment of erosion and ulceration of the esophagusFormula:C16H14F2N3NaO4SH2OPurezza:98.32%Colore e forma:SolidPeso molecolare:432.37Corza6
<p>Corza6 is a potent and selective peptide inhibitor of the human voltage-gated proton channel (hHv1). It binds to the external voltage sensor domain (VSD) loop in hHv1 at a resting membrane potential (RMP) of natural hyperpolarization in mammalian cells with a Kd of approximately 1 nM. Corza6 facilitates sperm capacitation and permits sustained production of reactive oxygen species (ROS) in leukocytes (WBC).</p>Formula:C203H293N55O61S7Colore e forma:SolidPeso molecolare:4704.29Esomeprazole sodium-d6
CAS:Esomeprazole sodium-d6 is a deuterated compound of Esomeprazole sodium.Formula:C17H12D6N3NaO3SPeso molecolare:373.44(R)-Lansoprazole
CAS:(R)-Lansoprazole (T 168390) is the R-isomer of lansoprazole and a substituted benzimidazole prodrug with selective and irreversible proton pump inhibitorFormula:C16H14F3N3O2SPurezza:98.09% - 98.99%Colore e forma:Brown SolidPeso molecolare:369.36Esomeprazole Magnesium trihydrate
CAS:<p>Esomeprazole Magnesium trihydrate ((S)-Omeprazole magnesium trihydrate) is a proton pump inhibitor indicated for the short-term treatment of gastroesophageal</p>Formula:C34H42MgN6O9S2Purezza:98.52%Colore e forma:Off-White PowderPeso molecolare:767.17Thonzonium Bromide
CAS:<p>Thonzonium bromide: antimicrobial surfactant, similar to Farnesol, blocks proton transport, inhibits bone loss (EC50=69 μM).</p>Formula:C32H55BrN4OPurezza:98.48% - 99.94%Colore e forma:SolidPeso molecolare:591.71Rabeprazole Sulfide
CAS:Rabeprazole Sulfide (Rabeprazole Related Compound E) is an antiulcer drug in the class of proton pump inhibitors.Formula:C18H21N3O2SPurezza:99.34% - 99.78%Colore e forma:Off-White Crystalline PowderPeso molecolare:343.44Vonoprazan
CAS:Vonoprazan (TAK-438 (free base)) is an orally active potassium-competitive acid blocker.Vonoprazan can be used for the treatment of gastroduodenal ulcer andFormula:C17H16FN3O2SPurezza:99.87% - 99.92%Colore e forma:SolidPeso molecolare:345.39Esomeprazole Sodium
CAS:Esomeprazole Sodium ((S)-Omeprazole sodium) is the S-isomer of omeprazole with selective and irreversible proton pump inhibitor activity.Formula:C17H18N3O3S·NaPurezza:98.17% - >99.99%Colore e forma:SolidPeso molecolare:367.4Tegoprazan
CAS:Tegoprazan is an orally active, highly selective gastric H+/K+-ATPase inhibitor.Cost-effective and quality-assured.Formula:C20H19F2N3O3Purezza:98.22%Colore e forma:SolidPeso molecolare:387.38Chebulinic acid
CAS:Chebulinic acid is a potent inhibitor of M. tuberculosis DNA gyrase. It also can inhibit SMAD-3 phosphorylation and H+ K+-ATPase activity.Formula:C41H32O27Purezza:98.91% - 99.71%Colore e forma:SolidPeso molecolare:956.68Ilaprazole sodium
CAS:<p>Ilaprazole sodium (IY-81149 sodium) , a substituted benzimidazole prodrug, is a selective and irreversible proton pump inhibitor.</p>Formula:C19H17N4NaO2SPurezza:99.06%Colore e forma:SolidPeso molecolare:388.42Esomeprazole Magnesium
CAS:Esomeprazole Magnesium (NEXIUM) is the S-isomer of omeprazole, can reduce gastric acid secretion with selective and irreversible proton pump inhibitor activity.Formula:C34H36MgN6O6S2Purezza:98.76% - 99.73%Colore e forma:SolidPeso molecolare:713.12Abscisic Acid
CAS:Abscisic Acid (Dormin) is a plant hormone, which is involved in many plant developmental processes, modulates ion homeostasis and metabolism.Formula:C15H20O4Purezza:99.52% - 99.73%Colore e forma:White PowderPeso molecolare:264.32Pantoprazole sodium
CAS:Pantoprazole sodium is a proton pump inhibitor that irreversibly blocks gastric acid secretion by bonding with H+/K+-ATPase.Formula:C16H14F2N3NaO4SPurezza:96.92% - 99.81%Colore e forma:White To Off-White SolidPeso molecolare:405.35Ilaprazole
CAS:Ilaprazole (IY-81149) is a proton pump inhibitor used in the treatment of dyspepsia gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer.Formula:C19H18N4O2SPurezza:99.91%Colore e forma:SolidPeso molecolare:366.44Tenatoprazole
CAS:Tenatoprazole (TU-199), a prodrug of the proton pump inhibitor (PPI) class, can inhibit proton transport (IC50: 3.2 μM).Formula:C16H18N4O3SPurezza:99.57%Colore e forma:White Crystalline PowderPeso molecolare:346.4Esomeprazole
CAS:Esomeprazole is the S-isomer of omeprazole, inhibits the lysosomal cysteine protease legumain to prevent cancer metastasis.Formula:C17H19N3O3SPurezza:97.3%Colore e forma:SolidPeso molecolare:345.42Rabeprazole sodium
CAS:Rabeprazole sodium treats stomach ulcers and Zollinger-Ellison syndrome, blocking ATPase in gastric cells.Formula:C18H20N3NaO3SPurezza:98% - 99.912%Colore e forma:White Or Off White Crystalline PowderPeso molecolare:381.42Bafilomycin A1
CAS:<p>Bafilomycin A1 belongs to the macrolide class of antibiotics and is a V-ATPase (IC50=0.44 nM) that is specific and reversible.</p>Formula:C35H58O9Purezza:95.87% - 99.36%Colore e forma:SolidPeso molecolare:622.83Vonoprazan Fumarate
CAS:Vonoprazan Fumarate (TAK438) , a novel potassium-competitive acid blocker, inhibits gastric acid secretion.Formula:C21H20FN3O6SPurezza:98.94% - 99.98%Colore e forma:SolidPeso molecolare:461.46Pantoprazole
CAS:Pantoprazole (BY1023) is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal refluxFormula:C16H15F2N3O4SPurezza:97.16% - 99.63%Colore e forma:Almost White SolidPeso molecolare:383.37KM 91104
CAS:KM 91104 is a cell permeable inhibitor of V-ATPase. KM91104 specifically targets the interaction between V-ATPase subunit A3 and subunit B2.Formula:C14H12N2O4Purezza:99.04%Colore e forma:SolidPeso molecolare:272.26Diphyllin
CAS:<p>Diphyllin could be characterized as a new V-ATPase inhibitor in treating gastric cancer and inhibiting the phosphorylation of LRP6 in Wnt/β-catenin signaling.</p>Formula:C21H16O7Purezza:99.76% - 99.98%Colore e forma:SolidPeso molecolare:380.35ATP4A Protein, Human, Recombinant (His & Myc)
<p>ATP4A Protein, Human, Recombinant (His & Myc) is expressed in E.</p>Colore e forma:Lyophilized PowderPeso molecolare:54.6 kDa (predicted)Omeprazole Sodium
CAS:Omeprazole Sodium is a proton pump inhibitor(PPI) and suppresses gastric acid secretion.Formula:C17H18N3NaO3SPurezza:99.84%Colore e forma:Clear In WaterPeso molecolare:367.4WY-47766
CAS:WY-47766, a proton pump inhibitor, is used potentially for the treatment of postmenopausal osteoporosis.Formula:C14H13N3O2SPurezza:97.63% - 99.83%Colore e forma:SolidPeso molecolare:287.34Saviprazole
CAS:<p>Saviprazole (Hoe-731), a proton pump inhibitor, is used potentially for treatment of gastric ulcer.</p>Formula:C15H10F7N3O2S2Purezza:97.07% - 97.17%Colore e forma:SolidPeso molecolare:461.38Abeprazan hydrochloride
CAS:Abeprazan hydrochloride (Fexuprazan hydrochloride) is an effective reversible potassium-competitive acid blocker with oral activity, inhibiting H+, K+ -atPaseFormula:C19H18ClF3N2O3SPurezza:98.57%Colore e forma:SolidPeso molecolare:446.87Ilaprazole sodium hydrate
CAS:Ilaprazole sodium hydrate (IY-81149 sodium hydrate) is a proton pump inhibitor that blocks the transport of HSV particles.Formula:C19H21N4NaO4SPurezza:99.2%Colore e forma:SolidPeso molecolare:424.45Linaprazan
CAS:Linaprazan (AZD0865) inhibits gastric H+,K+-ATPase by K+-competitive binding with an IC50 of 1.0 μM.Formula:C21H26N4O2Purezza:99.54%Colore e forma:SolidPeso molecolare:366.46Pumaprazole
CAS:Pumaprazole (BY-841) is an antagonist of a reversible proton pump.Formula:C19H22N4O2Purezza:99.91%Colore e forma:SolidPeso molecolare:338.4Soraprazan
CAS:BS3 Crosslinker (Bis(sulfosuccinimidyl)suberate) is an ADC linker that can be used to synthesize antibody-coupled active molecules.Formula:C21H25N3O3Purezza:97.69% - 99.84%Colore e forma:SolidPeso molecolare:367.44(R)-(+)-Pantoprazole sodium
CAS:(R)-(+)-Pantoprazole ((R)-(+)-BY1023) sodium is a proton pump inhibitor used in the study of esophageal erosion and ulcers.Formula:C16H15F2N3NaO4SPeso molecolare:406.36V-ATPase-IN-1
CAS:V-ATPase-IN-1 (Compound 3b-03) is an inhibitor of Vacuolar-type H+-ATPases (V-ATPase), exhibiting an inhibition constant (IC50) of 194.80 μM and effectively targeting the V-ATPase subunit A with a dissociation constant (Kd) of 0.803 μM. This compound demonstrates insecticidal activity against M. separata (LC50 = 2.64 mM), aiding in the development of chemical insecticides.Formula:C21H20ClNO2Colore e forma:SolidPeso molecolare:353.84Zastaprazan
CAS:Zastaprazan (JP-1366, compound 6) is a potassium-competitive acid blocker and proton pump inhibitor that suppresses gastric acid secretion, indicated for GERD.Formula:C22H26N4OPurezza:99.97%Colore e forma:SolidPeso molecolare:362.48
