
Trasportatore di monoammine
I trasportatori di monoamine sono un gruppo di proteine di membrana responsabili della ricaptazione delle monoamine—come serotonina, dopamina e norepinefrina—dalla fessura sinaptica nei neuroni presinaptici. Questo processo è cruciale per regolare i livelli di neurotrasmettitori e mantenere una corretta neurotrasmissione. La disfunzione dei trasportatori di monoamine è associata a vari disturbi psichiatrici e neurologici, tra cui depressione, ansia e malattia di Parkinson. Presso CymitQuimica, offriamo una gamma di modulatori dei trasportatori di monoamine per supportare la tua ricerca in neurobiologia, salute mentale e farmacologia.
Trovati 30 prodotti di "Trasportatore di monoammine"
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Tetrabenazine
CAS:Tetrabenazine (Ro 1-9569) is a drug formerly used as an antipsychotic and treatment of various movement disorders.Formula:C19H27NO3Purezza:98% - 99.91%Colore e forma:White To Off-White White To Off-White SolidPeso molecolare:317.42Reserpine
CAS:Reserpine, an alkaloid from Rauwolfia roots, depletes neurotransmitters, used in treating hypertension and psychosis, but side effects restrict use.Formula:C33H40N2O9Purezza:98.85% - 99.99%Colore e forma:White Or Pale Buff To Slightly Yellowish Powder With A Bitter Taste (Ntp 1992)Peso molecolare:608.68FFN 511
CAS:Fluorescent false neurotransmitter (FFN)Formula:C17H20N2O2Purezza:98%Colore e forma:SolidPeso molecolare:284.35FFN 206 dihydrochloride
CAS:<p>FFN 206 dihydrochloride: fluorescent VMAT2 marker, detects subcellular sites, non-inhibitory to DAT.</p>Formula:C12H15ClN2O2Purezza:98.96% - >99.99%Colore e forma:SolidPeso molecolare:254.71VMAT2-IN-3
VMAT2-IN-3 (compound 10) is a potent inhibitor of vesicular monoamine transporter 2 (VMAT2), with a Ki value of 0.71 nM, showing promise for research in neurological or psychiatric disorders.Formula:C22H35NO4Peso molecolare:377.25661GZ-793A
CAS:GZ-793A suppresses dopamine uptake at the vesicular monoamine transporter-2 (VMAT2. A lobelane analog, GZ-793A interacts with the vesicular monoamine transporter-2 to inhibit the effect of methamphetamine.Formula:C26H38ClNO4Peso molecolare:464.043,4-Dihydroxypyrovalerone HCl
CAS:3,4-Dihydroxypyrovalerone HCl is an analog of Pyrovalerone. Pyrovalerone inhibits the dopamine transporter (DAT), serotonin transporter (SERT), and norepinephrine transporter (NET).Formula:C15H22ClNO3Colore e forma:SolidPeso molecolare:299.79LY-368975 hydrochloride
CAS:<p>LY-368975 hydrochloride is a bioactive chemical.</p>Formula:C17H22ClNOSColore e forma:SolidPeso molecolare:323.88Tetrabenazine-d6
CAS:Tetrabenazine D6 is the deuterium-labeled Tetrabenazine. Tetrabenazine is a VMAT-inhibitor used for the treatment of hyperkinetic movement disorder.Formula:C19H27NO3Purezza:98%Colore e forma:SolidPeso molecolare:323.46NBI-98782
CAS:NBI-98782 ((+)-α-DHTBZ) is an inhibtior of vesicular monoamine transporter (VMAT2) (Ki: 0.97 nM)Formula:C19H29NO3Purezza:99.29%Colore e forma:SolidPeso molecolare:319.44Tetrabenazine Racemate
CAS:Tetrabenazine Racemate (Rubigen) is a selective and reversible inhibitor of vesicular monoamine transporter-2 (VMAT-2).Formula:C19H27NO3Purezza:98.65% - 98.86%Colore e forma:SolidPeso molecolare:317.42Tetrabenazine methanesulfonate
CAS:Tetrabenazine methanesulfonate: ex-antipsychotic/therapy for movement disorders, blocks neurotransmitter uptake, labels vesicle transport.Formula:C20H31NO6SPurezza:98%Colore e forma:SolidPeso molecolare:413.53Netarsudil free base
CAS:Netarsudil (AR-11324), a ROCK inhibitor, treats glaucoma by increasing eye outflow and lowering IOP, with mild hyperemia as a side effect.Formula:C28H27N3O3Colore e forma:SolidPeso molecolare:453.53Valbenazine
CAS:Valbenazine (NBI-98854), a highly selective vesicular monoamine transporter 2(VMAT2) inhibitor, is approved for the treatment of tardive dyskinesia.Formula:C24H38N2O4Purezza:97.58%Colore e forma:SolidPeso molecolare:418.57Nisoxetine
CAS:Nisoxetine is a selective NET (noradrenaline transporter) inhibitor (Kd=0.76 nM) capable of blocking voltage-gated sodium channels.Formula:C17H21NO2Purezza:98.71%Colore e forma:SolidPeso molecolare:271.35Decynium 22
CAS:Decynium 22 is a plasma membrane monoamine transporter (PMAT) inhibitorFormula:C23H23IN2Purezza:99.92%Colore e forma:Dark Red CrystalsPeso molecolare:454.35FFN 511 hydrochloride
CAS:FFN 511 hydrochloride is a fluorescent pseudo-neurotransmitter (FFNs) targeting VMA T2 that can be used to label baraminergic nerve endings.Formula:C17H21ClN2O2Purezza:99.83%Colore e forma:SoildPeso molecolare:320.81Talopram hydrochloride
CAS:noradrenalin transporter (NET) inhibitorFormula:C20H26ClNOPurezza:98%Colore e forma:SolidPeso molecolare:331.88Indatraline
CAS:Indatraline is a nonselective monoamine transporter inhibitor.Formula:C16H15Cl2NColore e forma:SolidPeso molecolare:292.2FFN200 dihydrochloride
CAS:FFN200 is a vesicular monoamine transporter 2 (VMAT2) substrate that selectively traces monoamine exocytosis in both neuronal cell culture and brain tissue.Formula:C11H14Cl2N2O2Colore e forma:SolidPeso molecolare:277.15Nisoxetine hydrochloride
CAS:Nisoxetine hydrochloride is a noradrenaline transporter (NET) inhibitorFormula:C17H21NO2·HClPurezza:99.21%Colore e forma:White SolidPeso molecolare:307.82GZ-11608
CAS:GZ-11608, a selective and potent inhibitor of vesicular monoamine transporter-2 (VMAT2), presents a high affinity with a Ki value of 25 nM. It effectively reduces dopamine release induced by methamphetamine from isolated synaptic vesicles in brain dopaminergic neurons. GZ-11608 also demonstrates rapid penetration into the brain without exhibiting neurotoxicity, making it a valuable compound for researching methamphetamine use disorder [1].Formula:C19H25NOPeso molecolare:283.41VMAT2-IN-I HCl
CAS:VMAT2-IN-I HCl is an inhibitor of vesicular monoamine transporter-2. It also has 15- fold greater affinity than GZ- 793A.Formula:C25H32ClF4NO4Purezza:98%Colore e forma:SolidPeso molecolare:521.97Imipramine pamoate
CAS:Imipramine pamoate, a potent antidepressant [1] [2], is a chemical compound widely recognized for its efficacy in treating depressive disorders.Formula:C61H64N4O6Colore e forma:SolidPeso molecolare:949.18(2S,3S,11bR)-Dihydrotetrabenazine
CAS:(2S,3S,11bR)-Dihydrotetrabenazine ((2S,3S,11bR)-DHTBZ) is a highly selective inhibitor of vesicular monoamine transporter 2 (VMAT2) with a Ki value of 593 nM. It suppresses the vesicular transport of monoamine neurotransmitters, such as dopamine and serotonin, leading to reduced release into the synaptic cleft. This compound holds potential for research in Huntington's disease and other hyperkinetic movement disorders.Formula:C19H29NO3Colore e forma:SolidPeso molecolare:319.44Lafadofensine (D-(-)-Mandelic acid)
Lafadofensine D-(-)-Mandelic acid is a monoamines reuptake inhibitor with adequate effects when administered short-term.Formula:C32H32F2N2O6Colore e forma:SolidPeso molecolare:578.6Valbenazine tosylate
CAS:<p>Valbenazine tosylate, the tosylate salt of valbenazine, is a vesicular monoamine transporter 2 (VMAT2) inhibitor with a Ki value of 150 nM while displaying no</p>Formula:C38H54N2O10S2Purezza:98%Colore e forma:SolidPeso molecolare:762.973-Bromoamphetamine hydrochloride
CAS:3-Bromoamphetamine hydrochloride is a para-substituted amphetamine that functions as a monoamine releaser.Formula:C9H13BrClNColore e forma:SolidPeso molecolare:250.563(+)-Tetrabenazine
CAS:(+)-Tetrabenazine ((3R,11bR)-Tetrabenazine) is a reversible vesicular monoamine transporter 2 (VMAT-2) inhibitor, inhibits transport by VMAT2 with 10-foldFormula:C19H27NO3Purezza:98.69%Colore e forma:SolidPeso molecolare:317.42VMAT2-IN-2 tosylate
CAS:<p>VMAT2-IN-2 tosylate is a potent inhibitor of VMAT2 and is applicable in the research of tardive dyskinesia [1].</p>Formula:C27H36F3NO6SPurezza:98%Colore e forma:SolidPeso molecolare:559.64Ref: TM-T79061
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