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Trasportatore di monoammine

Trasportatore di monoammine

I trasportatori di monoamine sono un gruppo di proteine di membrana responsabili della ricaptazione delle monoamine—come serotonina, dopamina e norepinefrina—dalla fessura sinaptica nei neuroni presinaptici. Questo processo è cruciale per regolare i livelli di neurotrasmettitori e mantenere una corretta neurotrasmissione. La disfunzione dei trasportatori di monoamine è associata a vari disturbi psichiatrici e neurologici, tra cui depressione, ansia e malattia di Parkinson. Presso CymitQuimica, offriamo una gamma di modulatori dei trasportatori di monoamine per supportare la tua ricerca in neurobiologia, salute mentale e farmacologia.

Trovati 30 prodotti di "Trasportatore di monoammine"

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  • Tetrabenazine

    CAS:
    Tetrabenazine (Ro 1-9569) is a drug formerly used as an antipsychotic and treatment of various movement disorders.
    Formula:C19H27NO3
    Purezza:98% - 99.91%
    Colore e forma:White To Off-White White To Off-White Solid
    Peso molecolare:317.42
  • Reserpine

    CAS:
    Reserpine, an alkaloid from Rauwolfia roots, depletes neurotransmitters, used in treating hypertension and psychosis, but side effects restrict use.
    Formula:C33H40N2O9
    Purezza:98.85% - 99.99%
    Colore e forma:White Or Pale Buff To Slightly Yellowish Powder With A Bitter Taste (Ntp 1992)
    Peso molecolare:608.68
  • FFN 511

    CAS:
    Fluorescent false neurotransmitter (FFN)
    Formula:C17H20N2O2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:284.35
  • FFN 206 dihydrochloride

    CAS:
    <p>FFN 206 dihydrochloride: fluorescent VMAT2 marker, detects subcellular sites, non-inhibitory to DAT.</p>
    Formula:C12H15ClN2O2
    Purezza:98.96% - >99.99%
    Colore e forma:Solid
    Peso molecolare:254.71
  • VMAT2-IN-3


    VMAT2-IN-3 (compound 10) is a potent inhibitor of vesicular monoamine transporter 2 (VMAT2), with a Ki value of 0.71 nM, showing promise for research in neurological or psychiatric disorders.
    Formula:C22H35NO4
    Peso molecolare:377.25661
  • GZ-793A

    CAS:
    GZ-793A suppresses dopamine uptake at the vesicular monoamine transporter-2 (VMAT2. A lobelane analog, GZ-793A interacts with the vesicular monoamine transporter-2 to inhibit the effect of methamphetamine.
    Formula:C26H38ClNO4
    Peso molecolare:464.04
  • 3,4-Dihydroxypyrovalerone HCl

    CAS:
    3,4-Dihydroxypyrovalerone HCl is an analog of Pyrovalerone. Pyrovalerone inhibits the dopamine transporter (DAT), serotonin transporter (SERT), and norepinephrine transporter (NET).
    Formula:C15H22ClNO3
    Colore e forma:Solid
    Peso molecolare:299.79
  • LY-368975 hydrochloride

    CAS:
    <p>LY-368975 hydrochloride is a bioactive chemical.</p>
    Formula:C17H22ClNOS
    Colore e forma:Solid
    Peso molecolare:323.88
  • Tetrabenazine-d6

    CAS:
    Tetrabenazine D6 is the deuterium-labeled Tetrabenazine. Tetrabenazine is a VMAT-inhibitor used for the treatment of hyperkinetic movement disorder.
    Formula:C19H27NO3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:323.46
  • NBI-98782

    CAS:
    NBI-98782 ((+)-α-DHTBZ) is an inhibtior of vesicular monoamine transporter (VMAT2) (Ki: 0.97 nM)
    Formula:C19H29NO3
    Purezza:99.29%
    Colore e forma:Solid
    Peso molecolare:319.44
  • Tetrabenazine Racemate

    CAS:
    Tetrabenazine Racemate (Rubigen) is a selective and reversible inhibitor of vesicular monoamine transporter-2 (VMAT-2).
    Formula:C19H27NO3
    Purezza:98.65% - 98.86%
    Colore e forma:Solid
    Peso molecolare:317.42
  • Tetrabenazine methanesulfonate

    CAS:
    Tetrabenazine methanesulfonate: ex-antipsychotic/therapy for movement disorders, blocks neurotransmitter uptake, labels vesicle transport.
    Formula:C20H31NO6S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:413.53
  • Netarsudil free base

    CAS:
    Netarsudil (AR-11324), a ROCK inhibitor, treats glaucoma by increasing eye outflow and lowering IOP, with mild hyperemia as a side effect.
    Formula:C28H27N3O3
    Colore e forma:Solid
    Peso molecolare:453.53
  • Valbenazine

    CAS:
    Valbenazine (NBI-98854), a highly selective vesicular monoamine transporter 2(VMAT2) inhibitor, is approved for the treatment of tardive dyskinesia.
    Formula:C24H38N2O4
    Purezza:97.58%
    Colore e forma:Solid
    Peso molecolare:418.57
  • Nisoxetine

    CAS:
    Nisoxetine is a selective NET (noradrenaline transporter) inhibitor (Kd=0.76 nM) capable of blocking voltage-gated sodium channels.
    Formula:C17H21NO2
    Purezza:98.71%
    Colore e forma:Solid
    Peso molecolare:271.35
  • Decynium 22

    CAS:
    Decynium 22 is a plasma membrane monoamine transporter (PMAT) inhibitor
    Formula:C23H23IN2
    Purezza:99.92%
    Colore e forma:Dark Red Crystals
    Peso molecolare:454.35
  • FFN 511 hydrochloride

    CAS:
    FFN 511 hydrochloride is a fluorescent pseudo-neurotransmitter (FFNs) targeting VMA T2 that can be used to label baraminergic nerve endings.
    Formula:C17H21ClN2O2
    Purezza:99.83%
    Colore e forma:Soild
    Peso molecolare:320.81
  • Talopram hydrochloride

    CAS:
    noradrenalin transporter (NET) inhibitor
    Formula:C20H26ClNO
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:331.88
  • Indatraline

    CAS:
    Indatraline is a nonselective monoamine transporter inhibitor.
    Formula:C16H15Cl2N
    Colore e forma:Solid
    Peso molecolare:292.2
  • FFN200 dihydrochloride

    CAS:
    FFN200 is a vesicular monoamine transporter 2 (VMAT2) substrate that selectively traces monoamine exocytosis in both neuronal cell culture and brain tissue.
    Formula:C11H14Cl2N2O2
    Colore e forma:Solid
    Peso molecolare:277.15
  • Nisoxetine hydrochloride

    CAS:
    Nisoxetine hydrochloride is a noradrenaline transporter (NET) inhibitor
    Formula:C17H21NO2·HCl
    Purezza:99.21%
    Colore e forma:White Solid
    Peso molecolare:307.82
  • GZ-11608

    CAS:
    GZ-11608, a selective and potent inhibitor of vesicular monoamine transporter-2 (VMAT2), presents a high affinity with a Ki value of 25 nM. It effectively reduces dopamine release induced by methamphetamine from isolated synaptic vesicles in brain dopaminergic neurons. GZ-11608 also demonstrates rapid penetration into the brain without exhibiting neurotoxicity, making it a valuable compound for researching methamphetamine use disorder [1].
    Formula:C19H25NO
    Peso molecolare:283.41
  • VMAT2-IN-I HCl

    CAS:
    VMAT2-IN-I HCl is an inhibitor of vesicular monoamine transporter-2. It also has 15- fold greater affinity than GZ- 793A.
    Formula:C25H32ClF4NO4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:521.97
  • Imipramine pamoate

    CAS:
    Imipramine pamoate, a potent antidepressant [1] [2], is a chemical compound widely recognized for its efficacy in treating depressive disorders.
    Formula:C61H64N4O6
    Colore e forma:Solid
    Peso molecolare:949.18
  • (2S,3S,11bR)-Dihydrotetrabenazine

    CAS:
    (2S,3S,11bR)-Dihydrotetrabenazine ((2S,3S,11bR)-DHTBZ) is a highly selective inhibitor of vesicular monoamine transporter 2 (VMAT2) with a Ki value of 593 nM. It suppresses the vesicular transport of monoamine neurotransmitters, such as dopamine and serotonin, leading to reduced release into the synaptic cleft. This compound holds potential for research in Huntington's disease and other hyperkinetic movement disorders.
    Formula:C19H29NO3
    Colore e forma:Solid
    Peso molecolare:319.44
  • Lafadofensine (D-(-)-Mandelic acid)


    Lafadofensine D-(-)-Mandelic acid is a monoamines reuptake inhibitor with adequate effects when administered short-term.
    Formula:C32H32F2N2O6
    Colore e forma:Solid
    Peso molecolare:578.6
  • Valbenazine tosylate

    CAS:
    <p>Valbenazine tosylate, the tosylate salt of valbenazine, is a vesicular monoamine transporter 2 (VMAT2) inhibitor with a Ki value of 150 nM while displaying no</p>
    Formula:C38H54N2O10S2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:762.97
  • 3-Bromoamphetamine hydrochloride

    CAS:
    3-Bromoamphetamine hydrochloride is a para-substituted amphetamine that functions as a monoamine releaser.
    Formula:C9H13BrClN
    Colore e forma:Solid
    Peso molecolare:250.563
  • (+)-Tetrabenazine

    CAS:
    (+)-Tetrabenazine ((3R,11bR)-Tetrabenazine) is a reversible vesicular monoamine transporter 2 (VMAT-2) inhibitor, inhibits transport by VMAT2 with 10-fold
    Formula:C19H27NO3
    Purezza:98.69%
    Colore e forma:Solid
    Peso molecolare:317.42
  • VMAT2-IN-2 tosylate

    CAS:
    <p>VMAT2-IN-2 tosylate is a potent inhibitor of VMAT2 and is applicable in the research of tardive dyskinesia [1].</p>
    Formula:C27H36F3NO6S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:559.64

    Ref: TM-T79061

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