PDE
Le fosfodiesterasi (PDEs) sono enzimi che idrolizzano i nucleotidi ciclici, come cAMP e cGMP, nelle loro forme inattive, svolgendo un ruolo chiave nella regolazione delle vie di segnalazione intracellulare. Gli inibitori delle PDE sono utilizzati nel trattamento di varie condizioni, tra cui malattie cardiovascolari, disfunzione erettile e disturbi respiratori, grazie alla loro capacità di modulare i livelli di nucleotidi ciclici. Presso CymitQuimica, offriamo una gamma di inibitori delle PDE per supportare la tua ricerca nella segnalazione cellulare, farmacologia e sviluppo terapeutico.
Trovati 165 prodotti di "PDE"
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Udenafil
CAS:Udenafil is an inhibitor of PDE5 .Formula:C25H36N6O4SPurezza:99.90%Colore e forma:Off-White SolidPeso molecolare:516.66GSK256066
CAS:<p>GSK256066 is a selective PDE4B(equal affinity to isoforms A-D) inhibitor with IC50 of 3.2 pM, >380, 000-fold selectivity versus PDE1/2/3/5/6 and >2500-fold</p>Formula:C27H26N4O5SPurezza:99.60% - 99.66%Colore e forma:SolidPeso molecolare:518.58Nortadalafil
CAS:Nortadalafil, a demethylated form of Tadalafil, is a PDE5 inhibitor used to treat ED and pulmonary arterial hypertension as Adcirca.Formula:C21H17N3O4Purezza:99.42%Colore e forma:SolidPeso molecolare:375.38Homo Sildenafil
CAS:Homo Sildenafil is an analog of Sildenafil, It acts as a phosphodiesterase inhibitor.Formula:C23H32N6O4SPurezza:99.88%Colore e forma:White SolidPeso molecolare:488.6GEBR-7b
CAS:<p>GEBR-7b (3-(Cyclopentyloxy)-4-methoxybenzaldehyde) is a phosphodiesterase-4 (PDE4) inhibitor.</p>Formula:C13H16O3Purezza:99.533%Colore e forma:SolidPeso molecolare:220.26Enoximone
CAS:Enoximone is a selective inhibitor of phosphodiesterase III (PDE3), with treatment of congestive heart failure.Formula:C12H12N2O2SPurezza:98.53%Colore e forma:SolidPeso molecolare:248.3MY-5445
CAS:<p>MY-5445 (N-(3-chlorophenyl)-4-phenylphthalazin-1-amine) is a specific inhibitor of phosphodiesterase type 5 (PDE5).</p>Formula:C20H14ClN3Purezza:99.77%Colore e forma:SolidPeso molecolare:331.8Amino Tadalafil
CAS:Amino tadalafil is a potent phosphodiesterase 5 (PDE5) inhibitor.Formula:C21H18N4O4Purezza:99.85%Colore e forma:White PowderPeso molecolare:390.39Sildenafil Mesylate
CAS:Sildenafil Mesylate is a mesylate form of Sildenafil, an inhibitor of Phosphodiesterase 5.Formula:C22H30N6O4S·xCH4O3SPurezza:99.84%Colore e forma:SolidPeso molecolare:570.68Lodenafil
CAS:Lodenafil (Hydroxyhomosildenafil) is a potent PDE5 inhibitor, with treatment of erectile dysfunction (ED)Formula:C23H32N6O5SPurezza:99.92%Colore e forma:SolidPeso molecolare:504.6[11C]MP 10
CAS:[11C]MP 10 (PF-2545920), a specific and effective PDE10A inhibitor (IC50=0.37 nM), is with more than1000-fold specificity activity over the PDE.Formula:C25H20N4OPurezza:99.5%Colore e forma:SolidPeso molecolare:391.45Osoresnontrine
CAS:Osoresnontrine is a potent and selective inhibitor of PDE9A (IC50 of 52 nM),and can be used in the research of memory.Formula:C16H17N5O2Purezza:99.93%Colore e forma:SolidPeso molecolare:311.34CP671305
CAS:CP671305 is an orally active, potent and selective inhibitor of phosphodiesterase-4-D.Formula:C23H19FN2O7Purezza:99.39%Colore e forma:SolidPeso molecolare:454.4Ziritaxestat
CAS:Ziritaxestat (GLPG1690), an autotaxin inhibitor, currently being evaluated in an exploratory phase 2 study in idiopathic pulmonary fibrosis patients.Formula:C30H33FN8O2SPurezza:97% - 99.85%Colore e forma:SolidPeso molecolare:588.7PDE10-IN-1
CAS:PDE10-IN-1 (SEP-0372814) is used for treating CNS and metabolic disorders.Formula:C21H19N7Purezza:99.65%Colore e forma:SolidPeso molecolare:369.42Lotamilast
CAS:<p>Lotamilast (RVT-501) is a phosphodiesterase 4 (PDE-4) inhibitor (IC50: 2.8 nM) potentially for the treatment of atopic dermatitis.</p>Formula:C26H24N4O5Purezza:97.03% - 99.29%Colore e forma:SolidPeso molecolare:472.49Enpp-1-IN-1
CAS:Enpp-1-IN-1 is an inhibitor of Ectonucleotide pyrophosphatase-phosphodiesterase 1 (enpp-1)Formula:C17H17N3O3SPurezza:97.52%Colore e forma:SolidPeso molecolare:343.4GSK256066 Trifluoroacetate
CAS:GSK 256066 Trifluoroacetate: selective PDE4 inhibitor, IC50: 3.2 pM for PDE4B, treats COPD.Formula:C29H27F3N4O7SColore e forma:SolidPeso molecolare:632.61Crisaborole-d4
Crisaborole-d4 (AN-2728-d4) is the deuterated form of Crisaborole. Crisaborole is a PDE4 inhibitor and also a cytokine release inhibitor.Formula:C14H6D4BNO3Colore e forma:SolidPeso molecolare:255.07Deltarasin
CAS:<p>Deltarasin is a small molecular inhibitor of KRAS-PDEδ interaction with Kd of 38 nM for binding to purified PDEδ.</p>Formula:C40H37N5OPurezza:99.4%Colore e forma:SolidPeso molecolare:603.75
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