Glucokinasi
La glucocinasi (GK) è un enzima che catalizza la fosforilazione del glucosio a glucosio-6-fosfato, un passaggio critico nella glicolisi. La GK è espressa principalmente nel fegato e nel pancreas, dove svolge un ruolo chiave nella regolazione dei livelli di glucosio nel sangue. Gli inibitori della GK sono di interesse nello studio dei disturbi metabolici come il diabete, poiché possono modulare il metabolismo del glucosio e la secrezione di insulina. Presso CymitQuimica, offriamo inibitori della glucocinasi per supportare la tua ricerca sul diabete, il metabolismo e lo sviluppo terapeutico.
Trovati 57 prodotti di "Glucokinasi"
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AMG-3969
CAS:AMG-3969 is an effective glucokinase-glucokinase regulatory protein interaction (GK-GKRP) disruptor (IC50: 4 nM).Formula:C21H20F6N4O3SPurezza:99.65%Colore e forma:SolidPeso molecolare:522.46Ref: TM-TQ0055
1mg55,00€5mg117,00€10mg182,00€25mg304,00€50mg420,00€100mg562,00€200mg780,00€1mL*10mM (DMSO)138,00€PFK-015
CAS:PFK-015 (PFK15) is an effective inhibitor of PFKFB3 (IC50: 110 nM) and inhibits PFKFB3 activity in Y cells (IC50: 20 nM).Formula:C17H12N2OPurezza:99.7% - 99.85%Colore e forma:SolidPeso molecolare:260.29Ref: TM-T2455
2mg40,00€5mg57,00€10mg88,00€25mg159,00€50mg250,00€100mg376,00€200mg550,00€1mL*10mM (DMSO)57,00€Genz-123346 free base
CAS:Genz 123346 is an inhibitor of GL1 synthase that blocks the conversion of ceramide to GL1.Formula:C24H38N2O4Purezza:99.41%Colore e forma:SolidPeso molecolare:418.57AM-2394
CAS:AM-2394 is an effective and specific Glucokinase agonist (GKA, EC50: 60 nM), which catalyzes the phosphorylation of glucose to glucose-6-phosphate.Formula:C22H25N5O4Purezza:99.01% - 99.62%Colore e forma:SolidPeso molecolare:423.46Ref: TM-T3312
2mg35,00€5mg52,00€10mg70,00€25mg111,00€50mg175,00€100mg279,00€200mg415,00€1mL*10mM (DMSO)52,00€Globalagliatin
CAS:Globalagliatin (LY2608204) has been used in trials studying the treatment of Diabetes Mellitus, Type 2.Formula:C28H37N3O3S3Purezza:98% - 99.56%Colore e forma:SolidPeso molecolare:559.81Palmitelaidic Acid
CAS:Palmitelaidic Acid (trans-Palmitoleic acid) is one of the most abundant fatty acids in serum and tissue.Formula:C16H30O2Purezza:99.76%Colore e forma:SolidPeso molecolare:254.41ML198
CAS:ML198: Activates & chaperones glucocerebrosidase; a potential Gaucher disease treatment lead.Formula:C17H14N4OPurezza:98.31%Colore e forma:SolidPeso molecolare:290.32Ref: TM-T8986
2mg48,00€5mg96,00€10mg131,00€25mg255,00€50mg380,00€100mg567,00€200mg748,00€1mL*10mM (DMSO)85,00€3PO
CAS:<p>3PO inhibits PFKFB3 (IC50: 22.9 µM) and cancer cell growth (IC50: 1.4-24 µM), reducing glucose uptake and key cellular metabolites.</p>Formula:C13H10N2OPurezza:99.56% - 99.67%Colore e forma:SolidPeso molecolare:210.23(E)-3PO
CAS:(E)-3PO is a PFKFB3 (6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase) inhibitor.Formula:C13H10N2OPurezza:98.8% - 98.92%Colore e forma:SolidPeso molecolare:210.23Ref: TM-T3260
2mg38,00€5mg58,00€10mg85,00€25mg154,00€50mg235,00€100mg416,00€200mg602,00€1mL*10mM (DMSO)60,00€YZ9
CAS:Y29 is a potent PFKFB3 inhibitor with an IC50 of 0.183 µM, and acts as a competitive inhibitor against Fru-6-P with a Ki of 0.094 µM[1].Formula:C12H10O5Purezza:99.59%Colore e forma:SolidPeso molecolare:234.2Piragliatin
CAS:Piragliatin (RO4389620) activates glucokinase, boosts insulin, and lowers glucose in type 2 diabetes.Formula:C19H20ClN3O4SColore e forma:SolidPeso molecolare:421.9Glucokinase activator 1
CAS:Glucokinase activator 1 is a liver-directed glucokinase activator (EC50: 34 nM).Formula:C27H20F2N2O7S2Purezza:98%Colore e forma:SolidPeso molecolare:586.58IHVR-11029
CAS:IHVR-11029 inhibits ER α-glucosidase, combats hemorrhagic fever viruses, and hinders enveloped virus morphogenesis.Formula:C18H27F2NO5Colore e forma:SolidPeso molecolare:375.41GKA-71
CAS:GKA-71 is an effective glucokinase activator (GKA).Formula:C21H23N3O6S2Colore e forma:SolidPeso molecolare:477.55Glucokinase activator 3
CAS:Glucokinase activator 3: potent GK activator, AC50=38 nM, potential for type 2 diabetes research.Formula:C26H33N2O9PS2Colore e forma:SolidPeso molecolare:612.65PF-04279405
CAS:PF-04279405 is a potent and selective glucokinase activator.Formula:C25H25FN4O4Colore e forma:SolidPeso molecolare:464.49PSN-GK1
CAS:PSN-GK1 is a potent activator of glucokinase (EC50: 0.13 μM).Formula:C20H23FN2O4S2Purezza:98%Colore e forma:SolidPeso molecolare:438.54Sinogliatin
CAS:Sinogliatin, a glucokinase activator, is used potentially for the treatment of type 2 diabetes.Formula:C22H27ClN4O5Colore e forma:SolidPeso molecolare:462.93(R)-PF-04991532
(R)-PF-04991532 is the R-enantiomer of PF-04991532 . PF-04991532 is a potent, hepatoselective glucokinase activator .Formula:C18H19F3N4O3Colore e forma:SolidPeso molecolare:396.36Cefetrizole
CAS:Ceftezole is an α-Glucosidase inhibitor (IC50: 2.1 μM; Ki: 0.578 μM).Formula:C16H15N5O4S3Purezza:98%Colore e forma:SolidPeso molecolare:437.52
