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Glucokinasi

Glucokinasi

La glucocinasi (GK) è un enzima che catalizza la fosforilazione del glucosio a glucosio-6-fosfato, un passaggio critico nella glicolisi. La GK è espressa principalmente nel fegato e nel pancreas, dove svolge un ruolo chiave nella regolazione dei livelli di glucosio nel sangue. Gli inibitori della GK sono di interesse nello studio dei disturbi metabolici come il diabete, poiché possono modulare il metabolismo del glucosio e la secrezione di insulina. Presso CymitQuimica, offriamo inibitori della glucocinasi per supportare la tua ricerca sul diabete, il metabolismo e lo sviluppo terapeutico.

Trovati 57 prodotti di "Glucokinasi"

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  • RO-28-1675
    Targetmol
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    RO-28-1675

    CAS:
    RO-28-1675 is a direct and selective glucokinase activator, the GK/GKRP complex,insulin secretion and type 2 diabetes.
    Formula:C18H22N2O3S2
    Purezza:98.13%
    Colore e forma:Solid
    Peso molecolare:378.51

    Ref: TM-T16793

  • GKA-22
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    GKA-22

    CAS:
    GKA-22 is a human glucokinase allosteric activator in the absence of glucose.
    Formula:C22H22N2O5S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:426.49

    Ref: TM-T25451

  • AMG-1694
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    AMG-1694

    CAS:
    AMG-1694 disrupts GK-GKRP complex, enhancing GK activity with 7 nM IC50; normalizes glucose in diabetic rodents without affecting normoglycemic animals.
    Formula:C23H30F3N3O4S2
    Purezza:98.37%
    Colore e forma:Solid
    Peso molecolare:533.63

    Ref: TM-T14212

  • CM-10-18
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    CM-10-18

    CAS:
    CM-10-18: potent ER α-glucosidase inhibitor, strong antiviral against hemorrhagic fever viruses, protects mice from dengue fatality.
    Formula:C17H35NO5
    Colore e forma:Solid
    Peso molecolare:333.46

    Ref: TM-T27050

  • AZD-1656
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    AZD-1656

    CAS:
    AZD-1656 is a glucokinase activator (GKA) that can cause dose-limiting hypoglycemia in normal animals used in embryofetal development studies and type 2
    Formula:C24H26N6O5
    Purezza:97.07% - 99.37%
    Colore e forma:Solid
    Peso molecolare:478.5

    Ref: TM-T26712

  • AZD1092
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    AZD1092

    CAS:
    AZD1092 is the glucokinase enzyme activator.
    Formula:C24H26N4O5
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:450.49

    Ref: TM-T23765

  • AR453588
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    AR453588

    CAS:
    AR453588 is an orally bioavailable anti-diabetic glucokinase activator (EC50: 42 nM) with anti-hyperglycemic activity.
    Formula:C25H25N7O2S2
    Colore e forma:Solid
    Peso molecolare:519.64

    Ref: TM-T10362

  • PF-04937319
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    PF-04937319

    CAS:
    <p>PF-04937319 activates glucokinase (EC50=154.4μM) with low hypoglycemia risk, researched for type 2 diabetes treatment.</p>
    Formula:C22H20N6O4
    Purezza:99.89%
    Colore e forma:Solid
    Peso molecolare:432.43

    Ref: TM-T16479

  • KDM4-IN-2
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    KDM4-IN-2

    CAS:
    KDM4-IN-2 is a potent and selective KDM4/KDM5 dual inhibitor with Kis of 4 and 7 nM for KDM4A and KDM5B, respectively.
    Formula:C25H26N6O
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:426.51

    Ref: TM-T11749

  • AR453588 hydrochloride
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    AR453588 hydrochloride

    CAS:
    AR453588 hydrochloride is an orally bioavailable anti-diabetic glucokinase activator (EC50: 42 nM) with anti-hyperglycemic activity.
    Formula:C25H26ClN7O2S2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:556.1

    Ref: TM-T10362L

  • WAY-297848
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    WAY-297848

    CAS:
    <p>WAY-297848 is a novel glucokinase activator for the prevention or treatment of hyperglycemia, diabetes mellitus, obesity, dyslipidemia, and metabolic syndrome.</p>
    Formula:C13H13ClN2O2S
    Purezza:98.19%
    Colore e forma:Solid
    Peso molecolare:296.77

    Ref: TM-T77784

  • Glucokinase activator 7
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    Glucokinase activator 7

    CAS:
    Glucokinase activator7 is an activator of glucose kinase (Glucokinase) and can be utilized in research on diabetes and hyperglycemia [refer to compound on page 176].
    Formula:C14H13N3O2S
    Colore e forma:Solid
    Peso molecolare:287.337

    Ref: TM-T205646

  • Logo CymitQuimica
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    GKA50 quarterhydrate

    GKA50 quarterhydrate: glucokinase activator, EC50 of 33 nM, boosts insulin, cuts glucose in rats.
    Formula:C26H30N2O7
    Colore e forma:Solid
    Peso molecolare:469.01

    Ref: TM-T63019

  • Gcase activator 2
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    Gcase activator 2

    CAS:
    Gcase activator 2 is a β-glucocerebrosidase activator that induces dimerization of GCase, increases lysosomal substrate metabolism.
    Formula:C21H24N4O2
    Purezza:99.51% - 99.76%
    Colore e forma:Solid
    Peso molecolare:364.44

    Ref: TM-T86495

  • Glucokinase activator 8
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    Glucokinase activator 8

    CAS:
    Glucokinase activator8 is an activator of glucose kinase (glucokinase).
    Formula:C14H13N3O2S
    Colore e forma:Solid
    Peso molecolare:287.337

    Ref: TM-T205380

  • MK-0941
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    MK-0941

    CAS:
    MK-0941 is an orally active and allosteric glucokinase activator, has potential in the treatment of type 2 diabetes.
    Formula:C22H28N4O9S2
    Colore e forma:Solid
    Peso molecolare:556.61

    Ref: TM-T12057

    1mg
    Fuori produzione
    Prodotto fuori produzione
  • GKA50
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    GKA50

    CAS:
    GKA50 stimulates insulin release from mouse islets of Langerhans and MIN6 cells. GKA50 shows significant glucose lowering in high fat fed female rats. GKA50 is a potent glucokinase activator (EC50=33 nM at 5 mM glucose).
    Formula:C26H28N2O6
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:464.51

    Ref: TM-T11401

    50mg
    Fuori produzione
    100mg
    Fuori produzione
    Prodotto fuori produzione