CymitQuimica logo
Glucokinasi

Glucokinasi

La glucocinasi (GK) è un enzima che catalizza la fosforilazione del glucosio a glucosio-6-fosfato, un passaggio critico nella glicolisi. La GK è espressa principalmente nel fegato e nel pancreas, dove svolge un ruolo chiave nella regolazione dei livelli di glucosio nel sangue. Gli inibitori della GK sono di interesse nello studio dei disturbi metabolici come il diabete, poiché possono modulare il metabolismo del glucosio e la secrezione di insulina. Presso CymitQuimica, offriamo inibitori della glucocinasi per supportare la tua ricerca sul diabete, il metabolismo e lo sviluppo terapeutico.

Trovati 56 prodotti di "Glucokinasi"

Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
prodotti per pagina.
  • AMG-3969
    Targetmol
    + Info

    AMG-3969

    CAS:
    AMG-3969 is an effective glucokinase-glucokinase regulatory protein interaction (GK-GKRP) disruptor (IC50: 4 nM).
    Formula:C21H20F6N4O3S
    Purezza:99.65%
    Colore e forma:Solid
    Peso molecolare:522.46

    Ref: TM-TQ0055

  • PFK-015
    Targetmol
    + Info

    PFK-015

    CAS:
    <p>PFK-015 (PFK15) is an effective inhibitor of PFKFB3 (IC50: 110 nM) and inhibits PFKFB3 activity in Y cells (IC50: 20 nM).</p>
    Formula:C17H12N2O
    Purezza:99.7% - 99.85%
    Colore e forma:Solid
    Peso molecolare:260.29

    Ref: TM-T2455

  • Genz-123346 free base
    Targetmol
    + Info

    Genz-123346 free base

    CAS:
    Genz 123346 is an inhibitor of GL1 synthase that blocks the conversion of ceramide to GL1.
    Formula:C24H38N2O4
    Purezza:99.41%
    Colore e forma:Solid
    Peso molecolare:418.57

    Ref: TM-T4049

  • AM-2394
    Targetmol
    + Info

    AM-2394

    CAS:
    AM-2394 is an effective and specific Glucokinase agonist (GKA, EC50: 60 nM), which catalyzes the phosphorylation of glucose to glucose-6-phosphate.
    Formula:C22H25N5O4
    Purezza:99.01% - 99.62%
    Colore e forma:Solid
    Peso molecolare:423.46

    Ref: TM-T3312

  • Globalagliatin
    Targetmol
    + Info

    Globalagliatin

    CAS:
    Globalagliatin (LY2608204) has been used in trials studying the treatment of Diabetes Mellitus, Type 2.
    Formula:C28H37N3O3S3
    Purezza:98% - 99.56%
    Colore e forma:Solid
    Peso molecolare:559.81

    Ref: TM-T3104

  • Palmitelaidic Acid
    Targetmol
    + Info

    Palmitelaidic Acid

    CAS:
    Palmitelaidic Acid (trans-Palmitoleic acid) is one of the most abundant fatty acids in serum and tissue.
    Formula:C16H30O2
    Purezza:99.76%
    Colore e forma:Solid
    Peso molecolare:254.41

    Ref: TM-T19500

  • ML198
    Targetmol
    + Info

    ML198

    CAS:
    ML198: Activates & chaperones glucocerebrosidase; a potential Gaucher disease treatment lead.
    Formula:C17H14N4O
    Purezza:98.31%
    Colore e forma:Solid
    Peso molecolare:290.32

    Ref: TM-T8986

  • 3PO
    Targetmol
    + Info

    3PO

    CAS:
    <p>3PO inhibits PFKFB3 (IC50: 22.9 µM) and cancer cell growth (IC50: 1.4-24 µM), reducing glucose uptake and key cellular metabolites.</p>
    Formula:C13H10N2O
    Purezza:99.56% - 99.67%
    Colore e forma:Solid
    Peso molecolare:210.23

    Ref: TM-T22223

  • (E)-3PO
    Targetmol
    + Info

    (E)-3PO

    CAS:
    (E)-3PO is a PFKFB3 (6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase) inhibitor.
    Formula:C13H10N2O
    Purezza:98.8% - 98.92%
    Colore e forma:Solid
    Peso molecolare:210.23

    Ref: TM-T3260

  • YZ9
    Targetmol
    + Info

    YZ9

    CAS:
    Y29 is a potent PFKFB3 inhibitor with an IC50 of 0.183 µM, and acts as a competitive inhibitor against Fru-6-P with a Ki of 0.094 µM[1].
    Formula:C12H10O5
    Purezza:99.59%
    Colore e forma:Solid
    Peso molecolare:234.2

    Ref: TM-T23552

  • Piragliatin
    Targetmol
    + Info

    Piragliatin

    CAS:
    <p>Piragliatin (RO4389620) activates glucokinase, boosts insulin, and lowers glucose in type 2 diabetes.</p>
    Formula:C19H20ClN3O4S
    Colore e forma:Solid
    Peso molecolare:421.9

    Ref: TM-T68976

  • Glucokinase activator 1
    Targetmol
    + Info

    Glucokinase activator 1

    CAS:
    Glucokinase activator 1 is a liver-directed glucokinase activator (EC50: 34 nM).
    Formula:C27H20F2N2O7S2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:586.58

    Ref: TM-T11418

  • IHVR-11029
    Targetmol
    + Info

    IHVR-11029

    CAS:
    <p>IHVR-11029 inhibits ER α-glucosidase, combats hemorrhagic fever viruses, and hinders enveloped virus morphogenesis.</p>
    Formula:C18H27F2NO5
    Colore e forma:Solid
    Peso molecolare:375.41

    Ref: TM-T27590

  • GKA-71
    Targetmol
    + Info

    GKA-71

    CAS:
    GKA-71 is an effective glucokinase activator (GKA).
    Formula:C21H23N3O6S2
    Colore e forma:Solid
    Peso molecolare:477.55

    Ref: TM-T25452

  • Glucokinase activator 3
    Targetmol
    + Info

    Glucokinase activator 3

    CAS:
    Glucokinase activator 3: potent GK activator, AC50=38 nM, potential for type 2 diabetes research.
    Formula:C26H33N2O9PS2
    Colore e forma:Solid
    Peso molecolare:612.65

    Ref: TM-T72284

  • PF-04279405
    Targetmol
    + Info

    PF-04279405

    CAS:
    PF-04279405 is a potent and selective glucokinase activator.
    Formula:C25H25FN4O4
    Colore e forma:Solid
    Peso molecolare:464.49

    Ref: TM-T68244

  • PSN-GK1
    Targetmol
    + Info

    PSN-GK1

    CAS:
    PSN-GK1 is a potent activator of glucokinase (EC50: 0.13 μM).
    Formula:C20H23FN2O4S2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:438.54

    Ref: TM-T10092

  • Sinogliatin
    Targetmol
    + Info

    Sinogliatin

    CAS:
    Sinogliatin, a glucokinase activator, is used potentially for the treatment of type 2 diabetes.
    Formula:C22H27ClN4O5
    Colore e forma:Solid
    Peso molecolare:462.93

    Ref: TM-T28781

  • Cefetrizole
    Targetmol
    + Info

    Cefetrizole

    CAS:
    Ceftezole is an α-Glucosidase inhibitor (IC50: 2.1 μM; Ki: 0.578 μM).
    Formula:C16H15N5O4S3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:437.52

    Ref: TM-T10751

  • RO-28-1675
    Targetmol
    + Info

    RO-28-1675

    CAS:
    RO-28-1675 is a direct and selective glucokinase activator, the GK/GKRP complex,insulin secretion and type 2 diabetes.
    Formula:C18H22N2O3S2
    Purezza:98.13%
    Colore e forma:Solid
    Peso molecolare:378.51

    Ref: TM-T16793