Aminopeptidasi
Le aminopeptidasi sono un gruppo di enzimi che catalizzano la scissione degli amminoacidi dall'estremità N-terminale di peptidi e proteine, svolgendo un ruolo cruciale nella maturazione e degradazione delle proteine. Questi enzimi sono coinvolti in vari processi fisiologici, tra cui la presentazione degli antigeni, la regolazione degli ormoni peptidici e l'omeostasi cellulare. Gli inibitori delle aminopeptidasi sono di interesse per il trattamento di malattie come il cancro, l'infiammazione e le malattie infettive. Presso CymitQuimica, offriamo una varietà di inibitori delle aminopeptidasi per supportare la tua ricerca in proteomica, sviluppo di farmaci e trattamento delle malattie.
Trovati 76 prodotti di "Aminopeptidasi"
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SDUY817
SDUY817 is a dual APN/NEP inhibitor with IC50 values of 0.29 μM for APN and 7.4 μM for NEP. It exhibits analgesic effects in a concentration- and time-dependent manner, making it a potential candidate for research in the field of neuropathic pain disorders.Formula:C18H16IN3O3Colore e forma:SolidPeso molecolare:449.24SDUY816
SDUY816 is an orally active dual APN/NEP inhibitor, with IC50 values of 0.68 μM for APN and 6.9 μM for NEP. It exhibits analgesic properties and demonstrates good safety and pharmacokinetic profiles, having an oral bioavailability of 27% and a half-life of 4.02 hours in rats (oral, 10 mg/kg). SDUY816 is applicable for research in the field of neuropathic pain disorders.Formula:C18H16IN3O3Colore e forma:SolidPeso molecolare:449.24Leuhistin
CAS:Leuhistin is an aminopeptidases N inhibitor isolated from Bacillus laterosporus BMI156-14F1.Formula:C11H19N3O3Purezza:98%Colore e forma:White To Off-White SolidPeso molecolare:241.29Probestin
CAS:Probestin is an aminopeptidase M inhibitor, isolated from Streptomyces azureus MH663-2F6.Formula:C26H38N4O6Purezza:98%Colore e forma:SolidPeso molecolare:502.60ERAP1-IN-3
ERAP1-IN-3 (compound 13) is a potent inhibitor of endoplasmic reticulum aminopeptidase 1 (ERAP1), with a pIC50 value of 8.6. ERAP1-IN-3 shows potential for research in cancer immunotherapy and autoimmune disease studies.Formula:C22H22N2O4SColore e forma:SolidPeso molecolare:410.49Aminopeptidase N inhibitor 2
AminopeptidaseN inhibitor 2 is an APN inhibitor (IC50: 4.3 μM) with antitumor properties.
Formula:C12H16F2N2O4SColore e forma:SolidPeso molecolare:322.07988LTA4H-IN-4
LTA4H-IN-4 (compound 3) is an orally active inhibitor of LTA4H. It exhibits an IC50 value of 156 μM against hERG and is applicable for inflammation-related research.
HFI-142
CAS:HFI-142 is a inhibitor to aminopeptidase N; inhibit leukotriene A4 biosynthesis in red blood cells; inhibit dditional aminopeptidases.Formula:C17H16N2O4Colore e forma:SolidPeso molecolare:312.32Apstatin TFA
Apstatin TFA is a potent inhibitor of aminopeptidase P (APP), with Ki values of 2.6 µM for rat APP and 0.64 µM for human APP. This compound also exhibits cardioprotective properties.Formula:C25H34F3N5O7Colore e forma:SolidPeso molecolare:573.56N-Acetyl-β-Asp-Glu
CAS:N-Acetyl-β-Asp-Glu is a peptide neurotransmitter, the third most common neurotransmitter in the mammalian nervous system.Formula:C11H16N2O8Purezza:99.94%Colore e forma:SolidPeso molecolare:304.25Tosedostat
CAS:Tosedostat (CHR-2797), an oral M1 aminopeptidase inhibitor, turns into CHR-79888, blocks tumor cell proteins, causing cell death.Formula:C21H30N2O6Purezza:98.14% - 99.84%Colore e forma:SolidPeso molecolare:406.47DG051
CAS:DG051 is a potent leukotriene A4 hydrolase (LTA4H) inhibitor (IC50: 47 nM).Formula:C21H25Cl2NO4Purezza:98.26%Colore e forma:SolidPeso molecolare:426.33Ref: TM-TQ0047
2mg37,00€5mg74,00€10mg116,00€25mg239,00€50mg380,00€100mg610,00€200mg815,00€1mL*10mM (DMSO)84,00€Acebilustat
CAS:Acebilustat (CTX-4430) (ZK322) is an effective and specific leukotriene B4 hydrolase inhibitor.Formula:C29H27N3O4Purezza:99.59% - 99.88%Colore e forma:SolidPeso molecolare:481.54Ref: TM-T3715
2mg35,00€5mg55,00€10mg75,00€25mg138,00€50mg212,00€100mg315,00€200mg442,00€1mL*10mM (DMSO)62,00€L(+)-Leucinol
CAS:L(+)-Leucinol is a potent inhibitor of leucine aminopeptidase.Formula:C6H15NOPurezza:98%Colore e forma:Clear Colorless To Slightly Yellow LiquidPeso molecolare:117.19Bestatin trifluoroacetate
CAS:Bestatin trifluoroacetate inhibits CD13/APN and leukotriene A4 hydrolase, used in cancer research.Formula:C18H25F3N2O6Colore e forma:SolidPeso molecolare:422.401ARM1
CAS:ARM1 is a potent inhibitor of aminopeptidase and epoxide hydrolase. The IC50 values are 7.61 µM for aminopeptidase and 12.4 µM for epoxide hydrolase.Formula:C16H14N2SPurezza:99.36%Colore e forma:SolidPeso molecolare:266.36Adamantanine
CAS:Adamantanine (NSC-145160) is an amino acid transport inhibitor.Formula:C11H17NO2Purezza:99.79%Colore e forma:SolidPeso molecolare:195.26DG-051
CAS:DG-051 is a novel leukotriene A4 (LTA4H) hydrolase inhibitor of leukotriene B4 biosynthesis.Formula:C21H24ClNO4Colore e forma:SolidPeso molecolare:389.87Firibastat
CAS:Firibastat (RB150) is a glutamyl aminopeptidase antagonist and an orally active brain penetrating prodrug of EC33.
Formula:C8H20N2O6S4Purezza:99.5%Colore e forma:SolidPeso molecolare:368.51Methyl arachidate
CAS:Methyl arachidate (Methyl Icosanoate) is an esterified form of arachidic acidFormula:C21H42O2Purezza:≥95%Colore e forma:White PowderPeso molecolare:326.56
