Aminopeptidasi
Le aminopeptidasi sono un gruppo di enzimi che catalizzano la scissione degli amminoacidi dall'estremità N-terminale di peptidi e proteine, svolgendo un ruolo cruciale nella maturazione e degradazione delle proteine. Questi enzimi sono coinvolti in vari processi fisiologici, tra cui la presentazione degli antigeni, la regolazione degli ormoni peptidici e l'omeostasi cellulare. Gli inibitori delle aminopeptidasi sono di interesse per il trattamento di malattie come il cancro, l'infiammazione e le malattie infettive. Presso CymitQuimica, offriamo una varietà di inibitori delle aminopeptidasi per supportare la tua ricerca in proteomica, sviluppo di farmaci e trattamento delle malattie.
Trovati 76 prodotti per "Aminopeptidasi".
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Bufexamac
CAS:Bufexamac (Bufexamic acid) is a COX inhibitor for IFN-α release with anti-inflammatory, analgesic, and antipyretic action.Formula:C12H17NO3Purezza:99.73%Colore e forma:White SolidPeso molecolare:223.27ERAP1-IN-1
CAS:ERAP1-IN-1 inhibits and allosterically activates ERAP1, affecting fluorogenic, chromogenic, and nonamer peptide substrates.Formula:C20H21F3N2O5SPurezza:98.95%Colore e forma:SolidPeso molecolare:458.45Ref: TM-T11221
1mg82,00€5mg161,00€1mL*10mM (DMSO)161,00€10mg259,00€25mg425,00€50mg583,00€100mg800,00€200mg1.071,00€BDM_92499
BDM_92499 is a nanomolar, selective IRAP inhibitor with an IC50 of 3.4 nM. It also inhibits ERAP1 and ERAP2, with IC50 values of 0.46 μM and 4.2 μM, respectively.Colore e forma:Odour SolidAmastatin hydrochloride
CAS:Amastatin HCl is an inhibitor of aminopeptidase. It also induces vasoconstriction.Formula:C21H39ClN4O8Colore e forma:SolidPeso molecolare:511.01Aclimostat
CAS:Aclimostat (ZGN-1061) is a MetAP2 inhibitor with strong preclinical results, improving obesity-related metrics and gene expression.Formula:C26H42N2O6Colore e forma:SolidPeso molecolare:478.63Relzomostat
CAS:Relzomostat inhibits MetAP2, with research potential for obesity and type 2 diabetes.Formula:C24H36F2N2O5Colore e forma:SolidPeso molecolare:470.558CD13-IN-1
CD13-IN-1 (Compound 5f) is a CD13 inhibitor with an IC50 value of 1.71 μM. It effectively suppresses the proliferation of various tumor cells, demonstrating antitumor activity.Colore e forma:Odour SolidERAP1 modulator-1
CAS:ERAP1 modulator-1 (Compound 1) is a regulator of endoplasmic reticulum aminopeptidase 1 (ERAP1) with an IC50 of less than 250 nM.Formula:C23H23F3N2O5SColore e forma:SolidPeso molecolare:496.5BAY-277
BAY-277 is a degrader of METAP2, with IC50 values of 5.8 nM for human METAP2 (hMETAP2) and 5.9 nM for mouse METAP2 (mMETAP2).Formula:C44H52N8O5Colore e forma:SolidPeso molecolare:772.93JNJ-40929837 succinate
CAS:JNJ-40929837 succinate is a selective, orally active inhibitor of LTA 4 H (leukotriene A 4 hydrolase). This compound effectively inhibits aminopeptidase activity, leading to the accumulation of Pro-Gly-Pro in serum, and can be utilized in asthma research [1].Formula:C22H24N4O2S·xC4H6O4Colore e forma:SolidLYS006 hydrochloride
CAS:LYS006 hydrochloride is a potent inhibitor of leukotriene A4 hydrolase (LTA4H) with an IC50 value of 2 nM. It is applicable in the study of inflammatory and autoimmune diseases. For further details, please refer to compound 29 in patent document WO2015092740A1.Formula:C16H15Cl2FN6O3Colore e forma:SolidPeso molecolare:429.23NGR peptide Trifluoroacetate
NGR peptide Trifluoroacetate contains an NGR motif recognized by CD13/APN in tumor neovasculature, used for targeted drug delivery in cancer research.Formula:C22H37F3N10O10S2Purezza:99.69%Colore e forma:White SolidPeso molecolare:722.72α-Cyclopentyl-4-(2-quinolinylmethoxy)benzeneacetic acid
CAS:α-Cyclopentyl-4-(2-quinolinylmethoxy)benzeneacetic acid was identified as possible dual inhibitors for hLTA4H and hLTC4S enzymes by the computer-aidedFormula:C23H23NO3Purezza:98.23% - 99.75%Colore e forma:White SolidPeso molecolare:361.43Ref: TM-T60040
1mg73,00€5mg146,00€1mL*10mM (DMSO)155,00€10mg208,00€25mg319,00€50mg447,00€100mg600,00€200mg808,00€ecMetAP-IN-1
CAS:ecMetAP-IN-1 可用作 QSAR 模型，以使用多元线性回归研究蛋氨酸氨基肽酶抑制剂作为抗癌剂。Formula:C13H11N3Purezza:99.34%Colore e forma:SolidPeso molecolare:209.25NGR peptide
CAS:Cell-penetrating peptideFormula:C20H36N10O8S2Purezza:98%Colore e forma:SolidPeso molecolare:608.69H-Val-βNA
CAS:H-Val-βNA, also known as L-Valine β-naphthylamide, serves as a substrate for aminopeptidase and Valine arylamidase activities.Formula:C15H18N2OColore e forma:SolidPeso molecolare:242.322Lys-psi(CH2NH)-trp(nps)-ome
CAS:Lys-psi(CH2NH)-trp(nps)-ome peptide bond replaced by CH2NH group.Formula:C24H31N5O4SColore e forma:SolidPeso molecolare:485.60Matlystatin A
CAS:Matlystatin A is an inhibitor of aminopeptidase. It shows multiple inhibitory activities against both aminopeptidase N and matrix metalloproteinases.Formula:C27H47N5O8SColore e forma:SolidPeso molecolare:601.76DG013A formate
DG013A (formate) is a tripeptide-mimicking inhibitor of hypophosphorous acid. It exhibits IC50 values of 33 nM for ERAP1 and 11 nM for ERAP2. This compound can be utilized in research related to autoimmune diseases and cancer.Formula:C27H37N4O4PCH2O2Colore e forma:SolidPeso molecolare:530.99Antho-rwamide I
CAS:Antho-rwamide I is an anthozoan neuropeptide.Formula:C31H46N10O7Colore e forma:SolidPeso molecolare:670.76SDUY817
SDUY817 is a dual APN/NEP inhibitor with IC50 values of 0.29 μM for APN and 7.4 μM for NEP. It exhibits analgesic effects in a concentration- and time-dependent manner, making it a potential candidate for research in the field of neuropathic pain disorders.Formula:C18H16IN3O3Colore e forma:SolidPeso molecolare:449.24SDUY816
SDUY816 is an orally active dual APN/NEP inhibitor, with IC50 values of 0.68 μM for APN and 6.9 μM for NEP. It exhibits analgesic properties and demonstrates good safety and pharmacokinetic profiles, having an oral bioavailability of 27% and a half-life of 4.02 hours in rats (oral, 10 mg/kg). SDUY816 is applicable for research in the field of neuropathic pain disorders.Formula:C18H16IN3O3Colore e forma:SolidPeso molecolare:449.24Leuhistin
CAS:Leuhistin is an aminopeptidases N inhibitor isolated from Bacillus laterosporus BMI156-14F1.Formula:C11H19N3O3Purezza:98%Colore e forma:White To Off-White SolidPeso molecolare:241.29Probestin
CAS:Probestin is an aminopeptidase M inhibitor, isolated from Streptomyces azureus MH663-2F6.Formula:C26H38N4O6Purezza:98%Colore e forma:SolidPeso molecolare:502.60ERAP1-IN-3
ERAP1-IN-3 (compound 13) is a potent inhibitor of endoplasmic reticulum aminopeptidase 1 (ERAP1), with a pIC50 value of 8.6. ERAP1-IN-3 shows potential for research in cancer immunotherapy and autoimmune disease studies.Formula:C22H22N2O4SColore e forma:SolidPeso molecolare:410.49Aminopeptidase N inhibitor 2
AminopeptidaseN inhibitor 2 is an APN inhibitor (IC50: 4.3 μM) with antitumor properties.Formula:C12H16F2N2O4SColore e forma:SolidPeso molecolare:322.07988LTA4H-IN-4
LTA4H-IN-4 (compound 3) is an orally active inhibitor of LTA4H. It exhibits an IC50 value of 156 μM against hERG and is applicable for inflammation-related research.HFI-142
CAS:HFI-142 is a inhibitor to aminopeptidase N; inhibit leukotriene A4 biosynthesis in red blood cells; inhibit dditional aminopeptidases.Formula:C17H16N2O4Colore e forma:White SolidPeso molecolare:312.32Apstatin TFA
Apstatin TFA is a potent aminopeptidase P inhibitor; Ki=0.64 μM; increases bradykinin levels; cardioprotective agent.Formula:C25H34F3N5O7Purezza:99.41%Colore e forma:White SolidPeso molecolare:573.56N-Acetyl-β-Asp-Glu
CAS:N-Acetyl-β-Asp-Glu is a peptide neurotransmitter, the third most common neurotransmitter in the mammalian nervous system.Formula:C11H16N2O8Purezza:99.94%Colore e forma:White SolidPeso molecolare:304.25Tosedostat
CAS:Tosedostat (CHR-2797), an oral M1 aminopeptidase inhibitor, turns into CHR-79888, blocks tumor cell proteins, causing cell death.Formula:C21H30N2O6Purezza:98.14% - 99.84%Colore e forma:White SolidPeso molecolare:406.47DG051
CAS:DG051 is a potent leukotriene A4 hydrolase (LTA4H) inhibitor (IC50: 47 nM).Formula:C21H25Cl2NO4Purezza:98.26%Colore e forma:SolidPeso molecolare:426.33Ref: TM-TQ0047
2mg34,00€5mg71,00€1mL*10mM (DMSO)79,00€10mg110,00€25mg225,00€50mg360,00€100mg577,00€200mg772,00€Acebilustat
CAS:Acebilustat (CTX-4430) (ZK322) is an effective and specific leukotriene B4 hydrolase inhibitor.Formula:C29H27N3O4Purezza:99.80% - 99.88%Colore e forma:SolidPeso molecolare:481.54Ref: TM-T3715
2mg35,00€5mg55,00€1mL*10mM (DMSO)62,00€10mg75,00€25mg138,00€50mg212,00€100mg315,00€200mg442,00€L(+)-Leucinol
CAS:L(+)-Leucinol is a potent inhibitor of leucine aminopeptidase.Formula:C6H15NOPurezza:98%Colore e forma:SolidPeso molecolare:117.19Bestatin trifluoroacetate
CAS:Bestatin trifluoroacetate inhibits CD13/APN and leukotriene A4 hydrolase, used in cancer research.Formula:C18H25F3N2O6Colore e forma:SolidPeso molecolare:422.401ARM1
CAS:ARM1 is a potent inhibitor of aminopeptidase and epoxide hydrolase. The IC50 values are 7.61 µM for aminopeptidase and 12.4 µM for epoxide hydrolase.Formula:C16H14N2SPurezza:99.36%Colore e forma:White SolidPeso molecolare:266.36Adamantanine
CAS:Adamantanine (NSC-145160) is an amino acid transport inhibitor.Formula:C11H17NO2Purezza:99.79%Colore e forma:White SolidPeso molecolare:195.26DG-051
CAS:DG-051 is a novel leukotriene A4 (LTA4H) hydrolase inhibitor of leukotriene B4 biosynthesis.Formula:C21H24ClNO4Colore e forma:SolidPeso molecolare:389.87Firibastat
CAS:Firibastat (RB150) is a glutamyl aminopeptidase antagonist and an orally active brain penetrating prodrug of EC33.Formula:C8H20N2O6S4Purezza:99.5%Colore e forma:SolidPeso molecolare:368.51Methyl arachidate
CAS:Methyl arachidate (Methyl Icosanoate) is an esterified form of arachidic acidFormula:C21H42O2Purezza:≥95%Colore e forma:White SolidPeso molecolare:326.56Puromycin aminonucleoside
CAS:Puromycin aminonucleoside (NSC-3056) increases podocyte permeability by modulating ZO-1 in an oxidative stress-dependent manner.Formula:C12H18N6O3Purezza:99.85% - 99.9%Colore e forma:White SolidPeso molecolare:294.31SC-57461A
CAS:SC 57461A is a potent and specific leukotriene A4 hydrolase (LTA4H) inhibitor.Formula:C20H26ClNO3Purezza:99.91%Colore e forma:White SolidPeso molecolare:363.9Bestatin hydrochloride
CAS:Bestatin hydrochloride (Ubenimex hydrochloride) is an inhibitor of aminopeptidase N (APN)/CD13 and aminopeptidase B.Formula:C16H25ClN2O4Purezza:99.84% - 99.93%Colore e forma:White SolidPeso molecolare:344.84Ref: TM-T3529
5mg49,00€1mL*10mM (DMSO)54,00€10mg71,00€25mg101,00€50mg165,00€100mg264,00€200mg404,00€500mg655,00€Bestatin
CAS:Bestatin (Ubenimex) competitively inhibits many aminopeptidases. Bestatin is a microbial metabolite and dipeptide with immunomodulatory and antitumor effects.Formula:C16H24N2O4Purezza:98% - 99.63%Colore e forma:SolidPeso molecolare:308.37Ref: TM-T1257
2mg34,00€5mg52,00€1mL*10mM (DMSO)58,00€10mg62,00€25mg82,00€50mg88,00€100mg105,00€500mg255,00€ERAP2-IN-1
CAS:ERAP2-IN-1 is a specific non-competitive ERAP2 inhibitor with IC50s of 27 μM for Arg-AMC and 44 μM for peptides.Formula:C20H21F3N2O5SColore e forma:SolidPeso molecolare:458.45M8891
CAS:M8891: Oral, reversible MetAP-2 inhibitor, brain-penetrant (IC50: 54nM; Ki: 4.33nM), hinders endothelial & tumor cell growth, antiangiogenic & antitumor.Formula:C20H17F2N3O3Colore e forma:SolidPeso molecolare:385.36Aminopeptidase-IN-1
CAS:Aminopeptidase-IN-1: potent IRAP blocker, Ki 7.7 μM, useful for cognitive/memory disorder research.Formula:C18H16N2O6Purezza:98.34%Colore e forma:SolidPeso molecolare:356.33TP-004
CAS:TP-004 is a potent and reversible methionine aminopeptidase 2 (MetAP2) inhibitor (IC50: 6 nM).Formula:C17H16F3N5OPurezza:98%Colore e forma:SolidPeso molecolare:363.34HFI-437
CAS:HFI-437 is a potent, non-peptidic, insulin-regulated aminopeptidase (IRAP) inhibitor with a K i of 20 nM and functions as a cognitive enhancer [1].Formula:C23H20N2O5Colore e forma:SolidPeso molecolare:404.42Aminopeptidase N Inhibitor
CAS:AP-N inhibitor: reversible, selective for AP-N/CD13 (IC50=25 μM), non-toxic to U937 cells at 100 μM.Formula:C17H10N2O8Colore e forma:SolidPeso molecolare:370.27
