Caseina chinasi
Le caseina chinasi sono una famiglia di proteine chinasi serina/treonina che regolano vari processi cellulari, tra cui la riparazione del DNA, i ritmi circadiani e la trasduzione del segnale. Queste chinasi sono coinvolte nella fosforilazione di numerose proteine e sono implicate in malattie come il cancro, i disturbi neurodegenerativi e le sindromi metaboliche. Presso CymitQuimica, offriamo una selezione di inibitori della caseina chinasi per supportare la tua ricerca nella trasduzione del segnale, nella regolazione del ciclo cellulare e nello sviluppo terapeutico.
Trovati 138 prodotti di "Caseina chinasi"
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Casein kinase 1δ-IN-17
CAS:Casein kinase1δ-IN-17 (compound 753) is an inhibitor of casein kinase 1δ (CK1δ). It is applicable in research related to neurodegenerative diseases.Formula:C14H14N4SColore e forma:SolidPeso molecolare:270.353Casein kinase 1δ-IN-13
CAS:Casein kinase1δ-IN-13 (compound 401) is an inhibitor of Casein kinase1δ. It is utilized in the research of neurodegenerative diseases.Formula:C15H13N3O2SColore e forma:SolidPeso molecolare:299.35Casein kinase 1δ-IN-28
CAS:Casein kinase1δ-IN-28 (Compound 4) is an inhibitor of CK1ε, with an IC50 of 0.0146 μM. The human liver microsome metabolism rate for Casein kinase1δ-IN-28 is 52%.Formula:C23H23FN6Colore e forma:SolidPeso molecolare:402.467CK1δ-IN-6
CAS:<p>CK1δ-IN-6 (Compound 303) is an inhibitor of Casein kinase 1δ, with potential applications in Alzheimer's disease research.</p>Formula:C23H17N3O4Colore e forma:SolidPeso molecolare:399.399WAY-606344
CAS:<p>WAY-606344 (Compound 97) is an inhibitor of Casein kinase 1δ and shows potential for Alzheimer's disease research.</p>Formula:C14H8ClN3O2Colore e forma:SolidPeso molecolare:285.685CK1δ-IN-5
CAS:<p>CK1δ-IN-5 (Compound 24) is an inhibitor of casein kinase 1δ (CK1δ) and can be used in the study of neurodegenerative diseases.</p>Formula:C22H21N5Colore e forma:SolidPeso molecolare:355.436Casein kinase 1δ-IN-27
CAS:<p>Casein kinase1δ-IN-27 (Compound 8) is an inhibitor of casein kinase 1 (CK1), effectively inhibiting CK1α, CK1δ, CK1ε, and p38α with IC50 values of 22, 16.5, 9.41, and 14.8 nM, respectively. It also suppresses DUX4 expression, with an IC50 of 10 nM.</p>Formula:C21H19FN6Colore e forma:SolidPeso molecolare:374.414CK1δ-IN-7
CAS:CK1δ-IN-7 (Compound 488) is an inhibitor of casein kinase 1δ (CK1δ).Formula:C23H23N5OColore e forma:SolidPeso molecolare:385.462p38α inhibitor 8
CAS:p38α inhibitor8 (Compound 1) demonstrates inhibitory activity against p38αMAPK and CK1δ, with IC50 values of 0.21 µM and 0.202 µM, respectively.Formula:C17H13FN6Colore e forma:SolidPeso molecolare:320.324dCK1α-2
dCK1α-2 is an orally effective CK1α molecular glue (Molecular Glue) degrader that targets p53 pathway-related targets. It demonstrates antitumor efficacy in mouse models by enhancing the expression of p53-related genes.Formula:C24H24ClN5O4Colore e forma:SolidPeso molecolare:481.93CK1δ-IN-9
CAS:CK1δ-IN-9 (Compound 8) is an inhibitor of casein kinase 1 (CK1), specifically targeting CK1δ with an IC50 of 1.4 nM. The compound also inhibits p38α and p38β with IC50 values of 0.25 μM and 0.78 μM, respectively. CK1δ-IN-9 exhibits favorable pharmacokinetic properties, including high oral bioavailability (70%) and moderate clearance.Formula:C16H12FN5Colore e forma:SolidPeso molecolare:293.298Casein kinase 1δ-IN-31
CAS:<p>Casein kinase1δ-IN-31 (Compound 16) is an inhibitor of casein kinase (CK), specifically targeting CK1α, CK1δ, and p38α, with IC50 values of 196 nM, 17 nM, and 18 nM, respectively. Additionally, Casein kinase1δ-IN-31 inhibits Double Homeobox 4 (DUX4) with an IC50 of 1200 nM.</p>Formula:C17H13FN4Colore e forma:SolidPeso molecolare:292.31MGD-28
CAS:MGD-28 is a Cullin-CRBN-dependent IKZF family protein degrader for IKZF1 (Ikaros), IKZF2 (Helios), IKZF3 (Aiolos) ,and CK1α, antiproliferative.Formula:C33H34FN7O3Purezza:99.39%Colore e forma:SolidPeso molecolare:595.67CK1δ-IN-10
CAS:CK1δ-IN-10 (Compound 85) is an inhibitor of casein kinase 1 (CK1), specifically targeting CK1δ (CSNKID), with an IC50 value of 0.255 μM.Formula:C17H11F4N5Colore e forma:SolidPeso molecolare:361.296Casein kinase 1δ-IN-16
CAS:Casein kinase1δ-IN-16 (compound 506) is an inhibitor of casein kinase 1δ (CK1δ). This compound is applicable in research related to neurodegenerative diseases.Formula:C17H12N4S2Colore e forma:SolidPeso molecolare:336.434CK1δ-IN-8
CAS:CK1δ-IN-8 (Compound 429) is a CK1δ inhibitor suitable for Alzheimer's disease research.Formula:C14H9N3O2S2Colore e forma:SolidPeso molecolare:315.37Casein kinase 1δ-IN-30
CAS:Casein kinase1δ-IN-30 (Compound 581) is an inhibitor of casein kinase 1δ (CK1δ). It can be utilized in research related to neurodegenerative diseases.Formula:C18H15BrN6O2SColore e forma:SolidPeso molecolare:459.32p38α MAPK/CK1δ inhibitor-1
CAS:<p>p38αMAPK/CK1δ inhibitor-1 (Compound 3) exhibits inhibitory activity against p38αMAPK and CK1δ, with IC50 values of 0.185 µM and 0.089 µM, respectively.</p>Formula:C24H17FN6O2Colore e forma:SolidPeso molecolare:440.429Casein kinase 1δ-IN-18
CAS:Casein kinase1δ-IN-18 (compound 660) is an inhibitor of casein kinase 1δ (CK1δ), which can be utilized for research in neurodegenerative diseases.Formula:C16H12ClN3O2S2Colore e forma:SolidPeso molecolare:377.868(R,R)-BMS-986397
CAS:(R,R)-BMS-986397 is a CK1α degrader with a DC50 ranging from 0.1 to 0.5 pM. This compound is applicable in leukemia research.Formula:C21H16ClF3N4O4Colore e forma:SolidPeso molecolare:480.82
