Caseina chinasi
Le caseina chinasi sono una famiglia di proteine chinasi serina/treonina che regolano vari processi cellulari, tra cui la riparazione del DNA, i ritmi circadiani e la trasduzione del segnale. Queste chinasi sono coinvolte nella fosforilazione di numerose proteine e sono implicate in malattie come il cancro, i disturbi neurodegenerativi e le sindromi metaboliche. Presso CymitQuimica, offriamo una selezione di inibitori della caseina chinasi per supportare la tua ricerca nella trasduzione del segnale, nella regolazione del ciclo cellulare e nello sviluppo terapeutico.
Trovati 138 prodotti di "Caseina chinasi"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
BTX161
CAS:BTX161: potent CKIα degrader, surpasses Lenalidomide in AML, triggers DDR + p53, stabilizes MDM2.Formula:C15H16N2O3Colore e forma:SolidPeso molecolare:272.3HDAC/CK2-IN-1
CAS:HDAC/CK2-IN-1 (compound 38) acts as an inhibitor of HDAC1 (IC 50 = 1.46 μM), HDAC6 (IC 50 = 0.66 μM), and CK2 (IC 50 = 3.67 μM). It demonstrates promising antiproliferative effects on various cell lines, including Jurkat, MCF-7, HCT-116, and HL-60.Formula:C15H18Br4N4O2Colore e forma:SolidPeso molecolare:605.95CK2-IN-4
CAS:CK2-IN-4 is a protein kinase (CK2) inhibitor with an IC50 value of 8.6 µM.Formula:C18H11N3O4SPurezza:99.65%Colore e forma:SolidPeso molecolare:365.36CK2α-IN-1
CAS:CK2α-IN-1 is a selective non-ATP-competitive CK2α inhibitor with an IC50 of 7.0 µM and a Ki of 1.6 µM.CK2α-IN-1 exhibits potential anticancer activity and canFormula:C16H11N3O4SPurezza:98%Colore e forma:SolidPeso molecolare:341.34CK1-IN-2
CAS:CK1-IN-2 (compound Nr.4) is a potent CK1 inhibitor p38a, and is used in DUX4 overexpression-associated diseases, such as muscular dystrophy.Formula:C17H12FN3O2Purezza:99.31%Colore e forma:SolidPeso molecolare:309.29Casein kinase 1δ-IN-1
CAS:Casein kinase 1δ-IN-1 (WAY-643895) is an inhibitor of casein kinase 1δ (CK1δ), which inhibits CK1δ.Formula:C11H7N3OSPurezza:99.89%Colore e forma:SolidPeso molecolare:229.26HS-276
CAS:HS-276, a selective oral TAK1 inhibitor (Ki: 2.5 nM), also targets CLK2, GCK, ULK2, MAP4K5; potential for RA research.Formula:C24H29N5O2Purezza:97.67% - 98.81%Colore e forma:SolidPeso molecolare:419.52PI-828
CAS:PI-828 (LY 294002), a PI3K inhibitor, researches PI3K function and aids stem cell differentiation into mesoderm.Formula:C19H18N2O3Purezza:99.95%Colore e forma:SolidPeso molecolare:322.36XL413 xHCl
CAS:<p>BMS-863233 HCl is an ATP-competitive Cdc7 inhibitor (IC50: 3.4 nM) that is potent and selective.BMS-863233 HCl inhibited CK2 and PIM1 with IC50 values of 215</p>Formula:C14H12ClN3O2·xHClPurezza:99.37% - 99.67%Colore e forma:SolidPeso molecolare:326.18BioE-1115
CAS:BioE-1115 is a selective and potent inhibitor of serine-threonine protein kinase (PASK, IC50 = 4 nM). BioE-1115 is a potent inhibitor of CK2α (IC50 = 10 μM).Formula:C19H18FN3O2Purezza:97.54%Colore e forma:SolidPeso molecolare:339.36PF-05236216
CAS:PF-05236216 is a potent, selective, brain-penetrant CK1δ/ε inhibitor that modulates circadian rhythms in mice, supporting sleep and metabolic research.Formula:C18H15FN4OPurezza:100% - 100%Colore e forma:SolidPeso molecolare:322.34Ac-VDVAD-CHO
CAS:Ac-VDVAD-CHO is an inhibitor of caspase-2 and caspase-3 (IC50: 46 nM for caspase-2 and 15 nM for caspase-3) [1].Formula:C23H37N5O10Purezza:98%Colore e forma:SolidPeso molecolare:543.57ON 108600
CAS:ON 108600 is a chemical inhibitor targeting CK2 (Casein Kinase 2), TNIK, and DYRK1, demonstrating IC50 values of 0.016 μM and 0.007 μM for DYRK1A and DYRK1B, 0.Formula:C22H14Cl2N2O6S2Purezza:98%Colore e forma:SolidPeso molecolare:537.39Casein kinase 1δ-IN-5
CAS:Casein kinase 1δ-IN-5 is a potent and selective CK-1δ inhibitor, exhibiting an IC50 of 47 nM, and demonstrates neuroprotective and anti-inflammatory effects inFormula:C16H11F3N2OSPurezza:98%Colore e forma:SolidPeso molecolare:336.33BAY-204
CAS:BAY-204 is a CSNK1α/δ inhibitor that can be used in the treatment of proliferative diseases.Formula:C29H26F3N5O2Colore e forma:SolidPeso molecolare:533.54TID43
CAS:TID43, a CK2 inhibitor, exhibits potent inhibition with an IC50 value of 0.3 μM. It is applicable in anti-angiogenic research [1].Formula:C10H3I4NO4Colore e forma:SolidPeso molecolare:708.755XL413 hydrochloride
CAS:XL413 hydrochloride (BMS-863233 Hydrochloride) is a potent, selective and ATP competitive inhibitor of Cdc7. XL413 hydrochloride also inhibits CK2 and PIM1.Formula:C14H13Cl2N3O2Purezza:98.81% - 99.8%Colore e forma:SolidPeso molecolare:326.18Casein Kinase II Inhibitor IV
CAS:Casein kinase II inhibitor IV is an effective small molecule inducer, which can be used to induce epidermal keratinocyte differentiation.Formula:C24H23N5O3Purezza:99.65% - 99.75%Colore e forma:SolidPeso molecolare:429.47Casein kinase 1δ-IN-10
CAS:Casein kinase 1δ-IN-10 is an inhibitor of casein kinase 1δ (CK1δ).Formula:C21H17N3O3Purezza:98%Colore e forma:SolidPeso molecolare:359.38Casein kinase 1δ-IN-4
CAS:"Casein kinase 1δ-IN-4 (compound 567) is a potent inhibitor of casein kinase 1δ with potential application in Alzheimer's disease research [1]."Formula:C16H12N6SPurezza:98%Colore e forma:SolidPeso molecolare:320.37
