Fattore Xa
Il fattore Xa è un enzima cruciale nella cascata della coagulazione che converte la protrombina in trombina, portando alla formazione di coaguli di sangue. L'inibizione del fattore Xa è una strategia terapeutica ampiamente utilizzata per prevenire e trattare i disturbi tromboembolici, come la trombosi venosa profonda, l'embolia polmonare e l'ictus. Presso CymitQuimica, offriamo inibitori del fattore Xa per supportare la tua ricerca in ematologia, salute cardiovascolare e terapia anticoagulante.
Trovati 91 prodotti per "Fattore Xa".
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Edoxaban impurity 6
CAS:Edoxaban impurity 6 is a byproduct of the anticoagulant Edoxaban, a potent oral factor Xa inhibitor with Kis of 0.561 nM. Used to prevent stroke.Formula:C16H22ClN5O3Colore e forma:SolidPeso molecolare:367.83FXIIa-IN-4
FXIIa-IN-4 (compound 22) is a potent and selective human FXIIa inhibitor, exhibiting IC50 values of 0.032 μM for FXIIa, 0.30 μM for thrombin, and >50 μM for FXIa. It is utilized in anticoagulant research.Formula:C11H9FN4O3Colore e forma:SolidPeso molecolare:264.06587FXIa-IN-15
CAS:FXIa-IN-15 (Compound (S)-10h) is an inhibitor of factor XIa (FXIa) and plasma kallikrein (PKa) with IC50 values of 0.38 nM and 59.2 nM, respectively. It exhibits anticoagulant properties by prolonging the 50% activated partial thromboplastin time (aPTT) with an EC1.5X of 0.55 μM.Formula:C32H23ClF3N7O4Colore e forma:SolidPeso molecolare:662.02WGU55
WGU55 is a selective and potent reversible type II transmembrane serine protease TMPRSS6 inhibitor with a Ki value of 12.15 nM. In KEK293 cells, WGU55 inhibits TMPRSS6 activity with an IC50 value of 138 nM. It displays a Ki value of 3510 nM for the homologous protease matriptase (SI=289) and a Ki value of 5.2 μM for the key coagulation protease factor Xa. WGU55 is applicable in the study of iron overload-related diseases, such as hereditary hemochromatosis.cMCoFx1
CAS:cMCoFx1 is an effective and selective FXIIa cyclic peptide inhibitor. It exhibits high binding affinity for FXIIa (KD: 900 pM) and potent inhibitory activity (Ki: 370 pM). cMCoFx1 effectively suppresses the intrinsic coagulation pathway, demonstrates high stability in serum, and shows no cytotoxicity.Formula:C146H232N52O44S6Colore e forma:SolidPeso molecolare:3612.12FXIIa-IN-1 HCl
CAS:FXIIa-IN-1 HCl is a selective inhibitor of Factor XIIa,and can be used to study thrombosis and inflammation induced by artificial surfaces.Formula:C21H17ClN2O6Purezza:99.61%Colore e forma:SolidPeso molecolare:428.82Suc-Ile-Glu(γ-pip)-Gly-Arg-pNA hydrochloride
CAS:Suc-Ile-Glu(γ-pip)-Gly-Arg-pNA hydrochloride is a chromogenic substrate specifically designed for factor Xa.Formula:C34H53ClN10O10Peso molecolare:797.299Chromozym PK
CAS:Chromozym PK is a chromogenic substrate for factor XII assay.Formula:C33H38N8O6Colore e forma:SolidPeso molecolare:642.70Rat Factor Xa
RatFactor Xa is derived from the activation of purified Rat Factor X using Russells' Viper Venom. Following activation, Russells' Viper Venom is removed.Colore e forma:Odour SolidO-Desmethyl apixaban sulfate sodium
O-Desmethyl apixaban sulfate sodium inhibits factor X (FXa) with a Ki of 58 μM,and is a major circulating metabolite of Apixaban in humans.Formula:C24H22N5NaO7SPurezza:98%Colore e forma:SolidPeso molecolare:547.52Methoxycarbonyl-D-Nle-Gly-Arg-pNA
CAS:Methoxycarbonyl-D-Nle-Gly-Arg-pNA is a synthetic trypsin substrate utilized for coagulation factors IXa (FIXa) and Xa (FXa), as evidenced by studies [1] [2] [3Formula:C22H34N8O7Colore e forma:SolidPeso molecolare:522.55Betrixaban-D6
CAS:Betrixaban D6 is a deuterium-labeled Betrixaban. Betrixaban is a selective and orally efficacious FXa inhibitor.Formula:C23H22ClN5O3Purezza:98%Colore e forma:SolidPeso molecolare:457.942Apixaban-D3
CAS:Apixaban D3 is a deuterated compound of apixaban. Apixaban (BMS-562247-01) is an orally active inhibitor of coagulation factor Xa with anticoagulant activity. Apixaban directly inhibits factor Xa, thereby interfering with the conversion of prothrombin to thrombin and preventing the formation of cross-linked fibrin clots.Formula:C25H22D3N5O4Peso molecolare:462.52Apixaban 13C,D3
CAS:Apixaban 13C,d3 is a deuterium labeling of Apixaban for isotopic tracing. Apixaban 13C,d3 is a selective inhibitor of coagulation factor XaFormula:C25H25N5O4Purezza:98%Colore e forma:White SolidPeso molecolare:463.5082FaX-IN-1
CAS:Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl) compound inhibits coagulation factor Xa, useful for thrombotic conditions study.Formula:C27H28N4O5Purezza:99.5%Colore e forma:SolidPeso molecolare:488.535Enoxaparin sodium
CAS:Enoxaparin, a low-weight heparin approved by FDA for STEMI, enhances antithrombin and prevents clotting by inhibiting factors XIa, IXa, Xa, IIa.Formula:C42H59N3Na4O35S2Purezza:98%Colore e forma:White SolidPeso molecolare:1322Darexaban
CAS:Darexaban (YM-150) selectively inhibits Factor Xa, reducing clotting and risk of heart/stroke events.Formula:C27H30N4O4Purezza:98.33%Colore e forma:White SolidPeso molecolare:474.5515Edoxaban Tosylate Monohydrate
CAS:Edoxaban(DU-176) is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention.Formula:C31H40ClN7O8S2Purezza:99.86% - 99.91%Colore e forma:SolidPeso molecolare:738.274Fondaparinux sodium
CAS:Fondaparinux sodium (SR-90107A) is an antithrombin-dependent factor Xa inhibitor with antithrombotic activity.Formula:C31H43N3Na10O49S8Purezza:98% - >99.99%Colore e forma:SolidPeso molecolare:1728.082Apixaban
CAS:Apixaban (BMS-562247-01) is an orally active inhibitor of coagulation factor Xa with anticoagulant activity.Formula:C25H25N5O4Purezza:99.82% - 99.94%Colore e forma:SolidPeso molecolare:459.4971
