Fattore Xa
Il fattore Xa è un enzima cruciale nella cascata della coagulazione che converte la protrombina in trombina, portando alla formazione di coaguli di sangue. L'inibizione del fattore Xa è una strategia terapeutica ampiamente utilizzata per prevenire e trattare i disturbi tromboembolici, come la trombosi venosa profonda, l'embolia polmonare e l'ictus. Presso CymitQuimica, offriamo inibitori del fattore Xa per supportare la tua ricerca in ematologia, salute cardiovascolare e terapia anticoagulante.
Trovati 87 prodotti di "Fattore Xa"
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Concizumab
CAS:Concizumab is an anti-TFPI monoclonal antibody (IgG4 type) that selectively binds to the Kunitz protease inhibitor (KPI) 2 domain of TFPI, thereby blocking thePurezza:> 95%Colore e forma:LiquidPeso molecolare:145.76 kDaFXIIa-IN-3
FXIIa-IN-3 (Compound 8) is an effective and selective inhibitor of Factor XIIa (FXIIa), with an IC50 of 0.045 μM. It demonstrates significant selectivity over related serine proteases, including FXIa, FXa, and FIXa. FXIIa-IN-3 is suitable for research in thromboembolic diseases.Formula:C14H16N4O6Peso molecolare:336.10698Boc-Ile-Glu-Gly-Arg-AMC
CAS:Boc-IEGR-AMC: fluorogenic substrate for factor Xa and Halocynthia roretzi acrosin.Formula:C34H50N8O10Purezza:98%Colore e forma:White PowderPeso molecolare:730.81Asundexian
CAS:Asundexian (BAY-2433334) is a potent and orally active inhibitor of the coagulation factor FXIa that directly and reversibly binds to the active site of FXIa,Formula:C26H21ClF4N6O4Purezza:99.89% - 99.90%Colore e forma:SolidPeso molecolare:592.93Chromozym PK
CAS:Chromozym PK is a chromogenic substrate for factor XII assay.Formula:C33H38N8O6Colore e forma:SolidPeso molecolare:642.70FXIIa-IN-4
FXIIa-IN-4 (compound 22) is a potent and selective human FXIIa inhibitor, exhibiting IC50 values of 0.032 μM for FXIIa, 0.30 μM for thrombin, and >50 μM for FXIa. It is utilized in anticoagulant research.Formula:C11H9FN4O3Peso molecolare:264.06587CH3OCO-D-CHA-Gly-Arg-pNA acetate
CAS:CH3OCO-D-CHA-Gly-Arg-pNA acetate serves as a chromogenic substrate for Factor Xa, as documented in sources [1] [2].Formula:C27H42N8O9Purezza:98%Colore e forma:SolidPeso molecolare:622.67D-Leu-Pro-Arg-Rh110-D-Pro acetate
D-Leu-Pro-Arg-Rh110-D-Pro acetate is a substrate for Factor XaI (FXIa) with binding affinity. This compound is formed by linking Rhodamine 110 to a peptide chain via a cleavable bond. The cleavage of this bond enhances the intensity of the fluorophore. D-Leu-Pro-Arg-Rh110-D-Pro acetate can be used to detect FXIa activity.Formula:C42H51N9O7·xC2H4O2Canine Factor Xa
<p>CanineFactor Xa is derived from purified Canine Factor X through activation by Russell's Viper Venom, after which the venom is removed.</p>Colore e forma:Odour SolidEdoxaban impurity 6
CAS:<p>Edoxaban impurity 6 is a byproduct of the anticoagulant Edoxaban, a potent oral factor Xa inhibitor with Kis of 0.561 nM. Used to prevent stroke.</p>Formula:C16H22ClN5O3Colore e forma:SolidPeso molecolare:367.83cMCoFx1
CAS:cMCoFx1 is an effective and selective FXIIa cyclic peptide inhibitor. It exhibits high binding affinity for FXIIa (KD: 900 pM) and potent inhibitory activity (Ki: 370 pM). cMCoFx1 effectively suppresses the intrinsic coagulation pathway, demonstrates high stability in serum, and shows no cytotoxicity.Formula:C146H232N52O44S6Colore e forma:SolidPeso molecolare:3612.12O-Desmethyl apixaban sulfate sodium
O-Desmethyl apixaban sulfate sodium inhibits factor X (FXa) with a Ki of 58 μM,and is a major circulating metabolite of Apixaban in humans.Formula:C24H22N5NaO7SPurezza:98%Colore e forma:SolidPeso molecolare:547.52Betrixaban-d6
CAS:Betrixaban D6 is a deuterium-labeled Betrixaban. Betrixaban is a selective and orally efficacious FXa inhibitor.Formula:C23H22ClN5O3Purezza:98%Colore e forma:SolidPeso molecolare:457.95Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
CAS:<p>Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl) compound inhibits coagulation factor Xa, useful for thrombotic conditions study.</p>Formula:C27H28N4O5Purezza:99.5%Colore e forma:SolidPeso molecolare:488.54Apixaban 13C,d3
CAS:Apixaban 13C,d3 is a deuterium labeling of Apixaban for isotopic tracing. Apixaban 13C,d3 is a selective inhibitor of coagulation factor XaFormula:C25H25N5O4Purezza:98%Colore e forma:SolidPeso molecolare:463.51Edoxaban hydrochloride
CAS:Edoxaban (DU-176b) HCl: Oral, selective Factor Xa inhibitor, Ki 0.561 nM; prevents thromboembolic disease.Formula:C24H31Cl2N7O4SColore e forma:SolidPeso molecolare:584.52Fondaparinux sodium
CAS:Fondaparinux sodium (SR-90107A) is an antithrombin-dependent factor Xa inhibitor with antithrombotic activity.Formula:C31H43N3Na10O49S8Purezza:98% - >99.99%Colore e forma:SolidPeso molecolare:1728.08Enoxaparin sodium
CAS:Enoxaparin, a low-weight heparin approved by FDA for STEMI, enhances antithrombin and prevents clotting by inhibiting factors XIa, IXa, Xa, IIa.Formula:C42H59N3Na4O35S2Purezza:98%Colore e forma:SolidPeso molecolare:1322Edoxaban Tosylate Monohydrate
CAS:Edoxaban(DU-176) is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention.Formula:C31H40ClN7O8S2Purezza:99.86% - 99.91%Colore e forma:SolidPeso molecolare:738.274-Chlorophenylurea
CAS:4-Chlorophenylurea (NSC-12971) is a novel orally bioavailable inhibitor of factor Xa.Formula:C7H7ClN2OPurezza:98.87%Colore e forma:White Granular / PrillPeso molecolare:170.6
