Anidrasi carbonica
L'anidrasi carbonica è un enzima che catalizza la conversione reversibile del diossido di carbonio e acqua in bicarbonato e protoni. Questo enzima svolge un ruolo cruciale nel mantenimento dell'equilibrio acido-base, nella respirazione e nel trasporto di anidride carbonica nel sangue. Gli inibitori dell'anidrasi carbonica sono utilizzati nel trattamento del glaucoma, dell'epilessia e del mal di montagna, nonché nella ricerca sull'omeostasi acido-base e lo scambio gassoso. Presso CymitQuimica, offriamo una gamma di inibitori dell'anidrasi carbonica e reagenti di alta qualità per supportare la tua ricerca in enzimologia, fisiologia respiratoria e sviluppo terapeutico.
Trovati 197 prodotti di "Anidrasi carbonica"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Bendroflumethiazide
CAS:Bendroflumethiazide (Naturetin) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810)Formula:C15H14F3N3O4S2Purezza:98% - >99.99%Colore e forma:Crystals From Dioxane SolidPeso molecolare:421.41hCAII-IN-7
hCAII-IN-7 (R-13) inhibits human CA I, II, IV, IX with K i of 60.7, 320.7, 2298, 35.2 nM respectively.Formula:C20H25N3O4SColore e forma:SolidPeso molecolare:403.5hCAII-IN-6
"hCAII-IN-6 (S-13) inhibits hCA II (4.4 nM) and isoforms I, IV, IX (9.2, 480.2, 14.7 nM). For glaucoma research."Formula:C20H25N3O4SColore e forma:SolidPeso molecolare:403.5CAIX-IN-4
CAIX-IN-4 (Compound 8b) is a selective inhibitor of carbonic anhydrase IX (CAIX) with an IC50 value of 0.32 μM. It holds potential for research in cancer, such as renal cell carcinoma.Colore e forma:Odour SolidhCA-I/hCA-II-IN-1
hCA-I/hCA-II-IN-1 (Compound P4) is a potent dual inhibitor of human carbonic anhydrase I (hCA-I) and human carbonic anhydrase II (hCA-II), with Ki values of 0.22 μM and 0.33 μM respectively. hCA-I/hCA-II-IN-1 is useful for research into diseases related to CA enzymes, including glaucoma, hypertension, and ulcers.Colore e forma:Odour SolidCarbonic anhydrase inhibitor 26
Compound 6T, designated as Carbonic anhydrase inhibitor26, acts as an inhibitor of Carbonic Anhydrase II (Carbonic AnhydraseII), exhibiting an IC50 value of 9.10 ± 0.26 μM.Formula:C17H14N6O4Colore e forma:SolidPeso molecolare:366.33Phenylsulfamide
CAS:<p>Phenylsulfamide (Compound 10), acting as an inhibitor of human carbonic anhydrase-II (hCA-II), exhibits a dissociation constant (Kd) of 45.50 μM and an</p>Formula:C6H8N2O2SColore e forma:SolidPeso molecolare:172.2AV22-149
AV22-149 (compound 22) is an inhibitor of Carbonic Anhydrase .Formula:C23H28F3N3O6S2Colore e forma:SolidPeso molecolare:563.61α-Glycosidase-IN-2
α-Glycosidase-IN-2 (compound 8b) is an inhibitor of α-glycosidase, displaying Ki values of 74.16 nM and 6.09 nM for aldose reductase and α-glycosidase, respectively. This compound is utilized in research related to diabetes.Formula:C25H22N6OS2Colore e forma:SolidPeso molecolare:486.61CA Ⅱ-IN-1
CAⅡ-IN-1 (compound 2i) is an inhibitor of the CA Ⅱ isozyme, exhibiting an IC50 of 0.44 µM. This compound is utilized in metabolic research.Formula:C18H19NO6SColore e forma:SolidPeso molecolare:377.41hCAXII-IN-9
hCAXII-IN-9 (Compound 3I) is a selective hCAXII inhibitor with Ki values of 28 nM for hCAXII, 7192.6 nM for hCAI, 188.6 nM for hCAII, and greater than 100000 nM for hCAIX. This compound may be utilized in anti-tumor research.Formula:C24H30N3O7PSPeso molecolare:535.15421(Iso)-Samixogrel
CAS:(Iso)-Samixogrel shows activity against Carbonic anhydrase and Cyclooxygenase 2.Formula:C25H25ClN2O4SPurezza:98.85%Colore e forma:SolidPeso molecolare:484.99Carbonic anhydrase inhibitor 24
Carbonic anhydrase inhibitor24 (Compound 11) is an inhibitor of human carbonic anhydrase. It exhibits Ki values of 10.7 nM and 7.5 nM against hCAs IX and XII, respectively.Formula:C16H14Cl2N2O6SPeso molecolare:431.99496Acesulfame
CAS:Acesulfame inhibits CA9/12 and can be used to study inflammation-related diseases.Formula:C4H5NO4SColore e forma:SolidPeso molecolare:163.15Carbonic anhydrase inhibitor 18
Carbonic anhydrase inhibitor18 (Compound 9) is an inhibitor of human carbonic anhydrase (hCA) isozymes, with Ki values of 604.8 nM for hCA I, 333.6 nM for hCA II, 1.9 nM for hCA IX, and 6.7 nM for hCA XII. Carbonic anhydrase inhibitor18 is applicable in cancer research.Formula:C26H28N4O6S2Peso molecolare:556.14503Carbonic anhydrase inhibitor 21
Compound 5h, known as Carbonic anhydrase inhibitor 21, is a specific inhibitor of carbonic anhydrase (hCA IX) with a K\(_i\) of 15.1 nM, demonstrating high selectivity compared to other isoforms studied. This compound is utilized in anticancer research.Formula:C32H48N4O10P2S2Peso molecolare:774.22871hCAIX/XII-IN-11
hCAIX/XII-IN-11 (Compound 6c) is an inhibitor of hCA IX and hCA XII, exhibiting Ki values of 0.7 μM for both isoforms. This compound is applicable in cancer research.Formula:C13H10FN3O4Peso molecolare:291.06553Chlorthalidone Impurity G
CAS:Chlorthalidone impurity G, a thiazide-like diuretic's contaminant, has mild antihypertensive properties and inhibits several carbonic anhydrase isoforms.Formula:C14H9Cl2NO2Colore e forma:SolidPeso molecolare:294.13GZ22-4
GZ22-4 is a near-infrared (NIR) fluorescent probe with a high affinity for carbonic anhydrase IX (CAIX), exhibiting a dissociation constant (Kd) of 0.2 nM. It is applicable in studies for visualizing CAIX-positive tumors.Formula:C88H126F3N6NaO24S4Peso molecolare:1858.75561Girentuximab
CAS:Girentuximab (G250) is an anti-carbonic anhydrase IX (CAIX) monoclonal antibody with anti-cancer activity for the study of uroepithelial carcinoma PET (ZiPUP).Colore e forma:LiquidPeso molecolare:145.55 kDahCAIX/XII-IN-10
hCAIX/XII-IN-10 (compound DK-8) is an inhibitor of Carbonic Anhydrase, showing potent inhibitory activity against the tumor-associated membrane-bound isoforms hCA IX and XII, with Ki values of 32.5 nM and 29.2 nM, respectively.Formula:C17H13N3O5SPeso molecolare:371.05759CAII/CAXII-IN-1
CAII/CAXII-IN-1 (compound 8d) is an inhibitor of CAII and CAXII, with IC50 values of 0.38 µM for CAII and 0.61 µM for CAXII.Colore e forma:Odour SolidChlorzolamide
CAS:CHLORZOLAMIDE is a sulfonamide-based inhibitor that exhibits cytotoxic effects on prostate cancer cells.Formula:C8H6ClN3O2S2Peso molecolare:275.74hCAII/XII-IN-1
hCAII/XII-IN-1 (compound 4l) is a potent inhibitor of hCAXII and hCAII, with Ki values of 8.4 nM and 9.4 nM, respectively. It plays a significant role in cancer research.Formula:C22H20N4O6S2Colore e forma:SolidPeso molecolare:500.547hCAII/IX-IN-1
hCAII/IX-IN-1 (compound 4o) is a potent inhibitor of hCAII and hCAIX, with Ki values of 7.4 nM and 7.0 nM, respectively. It plays a significant role in cancer research.Formula:C23H22N4O7S2Colore e forma:SolidPeso molecolare:530.573M 12325
CAS:M 12325 is used in the production of furosemide; rhinitis and occupational asthma were observed in workers from a lasamide production line.Formula:C7H5Cl2NO4SColore e forma:White To Almost White Solid PowderPeso molecolare:270.09Carbonic Anhydrase 12 Protein, Cynomolgus, Recombinant (His)
Carbonic anhydrases (CAs) are a family of enzymes involved in the pH regulation of metabolically active cells/tissues.Colore e forma:Lyophilized PowderPeso molecolare:32.04 kDa (predicted). Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.Acetazolamide-d3
CAS:Acetazolamide D3 is a deuterium-labeled Acetazolamide. Acetazolamide is a potent carbonic anhydrase inhibitor.Formula:C4H6N4O3S2Purezza:98%Colore e forma:SolidPeso molecolare:225.26Trichlormethiazide (Standard)
CAS:Trichlormethiazide (Standard) is the standard substance of Trichlormethiazide, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Trichlormethiazide (Naqua) is a short-acting, 3-dichloromethyl derivative of hydrochlorothiazide, belonging to the class of thiazide diuretics. Trichlormethiazide appears to block the active reabsorption of chloride and possibly sodium in the ascending loop of Henle, altering electrolyte transfer in the proximal tubule.Formula:C8H8Cl3N3O4S2Peso molecolare:380.664-Chloro-3-sulfamoylbenzoic acid
CAS:Compound PDK0044, with CAS No. 1205-30-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0044 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C7H6ClNO4SPeso molecolare:235.642,3-dihydro-1H-indene-5-sulfonamide
CAS:2,3-dihydro-1H-indene-5-sulfonamide is Carbonic anhydrase 12 (human) inhibitor.Formula:C9H11NO2SPurezza:99.89%Colore e forma:SolidPeso molecolare:197.25Ref: TM-T8611
1mg62,00€5mg123,00€10mg180,00€25mg298,00€50mg419,00€100mg567,00€200mg752,00€1mL*10mM (DMSO)104,00€Ethoxzolamide
CAS:Ethoxzolamide (L-643786) is a carbonic anhydrase inhibitor.Formula:C9H10N2O3S2Purezza:98.27% - 99.62%Colore e forma:Crystals From Ethyl Acetate + Skellysolve B SolidPeso molecolare:258.32Fluorometholone Acetate
CAS:Fluorometholone Acetate (Oxylone acetate) is a synthetic corticosteroid, used in the treatment of steroid responsive inflammatory conditions of the eye.Formula:C24H31FO5Purezza:99.76%Colore e forma:SolidPeso molecolare:418.50Dichlorphenamide
CAS:Dichlorphenamide (Diclofenamide) is a carbonic anhydrase inhibitor that is used in the treatment of glaucoma.Formula:C6H6Cl2N2O4S2Purezza:96.87% - 97.25%Colore e forma:Needles From Dimethylsulfoxide + Water SolidPeso molecolare:305.16Ref: TM-T6469
5mg50,00€10mg65,00€25mg87,00€50mg96,00€100mg140,00€200mg202,00€500mg340,00€1mL*10mM (DMSO)59,00€4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide
CAS:4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide (4-Amino-6-(trifluoromethyl)benzene-1,3-d) is a carbonic anhydrase inhibitor, used as a potential anti-Formula:C7H8F3N3O4S2Purezza:98.58%Colore e forma:SolidPeso molecolare:319.28Brinzolamide hydrochloride
Brinzolamide (AL-4862) HCl selectively inhibits carbonic anhydrase II, reducing IOP for glaucoma research. IC50: 3.2 nM.Colore e forma:SolidU-104
CAS:<p>U-104 (NSC-213841) is an effective carbonic anhydrase (CA) inhibitor for CA IX( Ki=45.1 nM) and CA XII(Ki=4.5 nM).</p>Formula:C13H12FN3O3SPurezza:98.76% - 99.88%Colore e forma:SolidPeso molecolare:309.32Dimethylfraxetin
CAS:Dimethylfraxetin (6,7,8-Trimethoxycoumarin) is a Carbonic anhydrase inhibitor(Ki：0.0097 μM)Formula:C12H12O5Purezza:99.96% - ≥95%Colore e forma:SolidPeso molecolare:236.22Dichlorphenamide disodium
CAS:Dichlorphenamide disodium: an oral carbonic anhydrase inhibitor that lowers eye pressure, promising for glaucoma study.Formula:C6H6Cl2N2Na2O4S2Colore e forma:SolidPeso molecolare:351.12Orthanilamide
CAS:Orthanilamide (Orthanilamide) is a molecule containing the sulfonamide functional group attached to an aniline.Formula:C6H8N2O2SPurezza:99.72% - 99.96%Colore e forma:White To Pale Cream Crystalline Powder Or CrystalsPeso molecolare:172.2Trichlormethiazide sodium
CAS:Trichlormethiazide sodium: oral thiazide diuretic, antihypertensive, boosts urine, Na/K excretion, may enhance renal clearance.Formula:C8H8Cl3N3NaO4S2Colore e forma:SolidPeso molecolare:403.63Taselisib
CAS:Taselisib (GDC-0032) is an oral PI3K alpha inhibitor with potential cancer-treating properties.Formula:C24H28N8O2Purezza:99.62% - 99.79%Colore e forma:SolidPeso molecolare:460.53Ref: TM-T1999
2mg46,00€5mg66,00€10mg92,00€25mg157,00€50mg197,00€100mg350,00€200mg522,00€500mg840,00€1mL*10mM (DMSO)66,00€Zolamide
CAS:Zolamide (CL 5343) may be used to prevent altitude sickness and reduce the symptoms.Formula:C2H4N4O2S2Purezza:99.75%Colore e forma:SolidPeso molecolare:180.21Acipimox sodium
CAS:Acipimox sodium is an antilipolytic, enhancing leptin, curbing lipolysis and FFAs, and boosting insulin sensitivity.Formula:C6H5N2NaO3Colore e forma:SolidPeso molecolare:176.11Benzenesulfonamide
CAS:Benzenesulfonamide (Benzosulfonamide) ia an inhibitor of carbonic anhydrases.Formula:C6H7NO2SPurezza:99.42% - 99.99%Colore e forma:White Crystalline PowderPeso molecolare:157.19Dorzolamide hydrochloride
CAS:Dorzolamide hydrochloride (MK507 hydrochloride) is the hydrochloride salt form of dorzolamide, an inhibitor of carbonic anhydrase, a zinc-containing enzyme thatFormula:C10H17ClN2O4S3Purezza:99.48% - 99.67%Colore e forma:White Off-White Crystalline PowderPeso molecolare:360.9Methyclothiazide
CAS:Methyclothiazide (Aquatensen) is a substituted benzothiadiazide, used to treat high blood pressure and fluid retention caused by various conditions includingFormula:C9H11Cl2N3O4S2Purezza:99.13%Colore e forma:SolidPeso molecolare:360.24Polmacoxib
CAS:Polmacoxib, a first-class NSAID, dual inhibitor of CA and COX-2, may hinder colorectal cancer growth in mice.Formula:C18H16FNO4SPurezza:97.88%Colore e forma:SolidPeso molecolare:361.39Ref: TM-T21294
2mg47,00€5mg70,00€10mg107,00€25mg173,00€50mg259,00€100mg378,00€200mg563,00€1mL*10mM (DMSO)77,00€Indisulam
CAS:Indisulam (E 7070) is a dual-action anticancer drug, blocking G1/S cell cycle transition by degrading cyclin E and activating p53/p21.Formula:C14H12ClN3O4S2Purezza:98.68% - 99.77%Colore e forma:SolidPeso molecolare:385.85Ref: TM-T4321
1mg35,00€2mg46,00€5mg66,00€10mg93,00€25mg137,00€50mg210,00€100mg314,00€1mL*10mM (DMSO)72,00€Benzolamide
CAS:Benzolamide (CL 11366) inhibits carbonic anhydrase effectively and low-threshold calcium currents in hippocampal pyramidal neurons.Formula:C8H8N4O4S3Purezza:99.31%Colore e forma:SolidPeso molecolare:320.37Ref: TM-T23782
5mg51,00€10mg88,00€25mg160,00€50mg235,00€100mg349,00€200mg515,00€1mL*10mM (DMSO)57,00€
