Anidrasi carbonica
L'anidrasi carbonica è un enzima che catalizza la conversione reversibile del diossido di carbonio e acqua in bicarbonato e protoni. Questo enzima svolge un ruolo cruciale nel mantenimento dell'equilibrio acido-base, nella respirazione e nel trasporto di anidride carbonica nel sangue. Gli inibitori dell'anidrasi carbonica sono utilizzati nel trattamento del glaucoma, dell'epilessia e del mal di montagna, nonché nella ricerca sull'omeostasi acido-base e lo scambio gassoso. Presso CymitQuimica, offriamo una gamma di inibitori dell'anidrasi carbonica e reagenti di alta qualità per supportare la tua ricerca in enzimologia, fisiologia respiratoria e sviluppo terapeutico.
Trovati 196 prodotti di "Anidrasi carbonica"
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4-(benzyloxy)benzene-1-sulfonamide
CAS:4-(benzyloxy)benzene-1-sulfonamide is inhibitor of human recombinant CA-7.Formula:C13H13NO3SPurezza:97.54%Colore e forma:SolidPeso molecolare:263.31EMAC10101d
CAS:compound EMAC10101d, bearing a 2,4-dichorophenyl substituent in position 4 of the dihydrothiazole ring, was the most potent and selective toward hCA II with an
Formula:C17H15Cl2N3O2S2Purezza:99.96%Colore e forma:SolidPeso molecolare:428.36WES-1
CAS:WES-1 (Compound 8g), a carbonic anhydrase IX inhibitor (Ki: 55.9 μM), exhibits broad-spectrum antiproliferative activity against various cancer cell lines,Formula:C20H20N4O3SPurezza:98%Colore e forma:SolidPeso molecolare:396.46AHR-15010
CAS:AHR-15010 is a novel anti-arthritic agent.Formula:C10H16N2O8S2Purezza:98%Colore e forma:SolidPeso molecolare:356.37hCAIX-IN-11
CAS:hCAIX-IN-11 inhibits carbonic anhydrases IX & XII with Ki of 32.7 nM & 623.5 nM, respectively.Formula:C21H15ClN4O3Colore e forma:SolidPeso molecolare:406.82hCAXII-IN-4
CAS:hCAXII-IN-4 is a selective and potent CA XII inhibitor with a Ki value of 6.4 nM for human CA XII.Formula:C22H27N5O6SColore e forma:SolidPeso molecolare:489.54Methazolamide-d6
CAS:Methazolamide-d6 is a GC/LC-MS standard for measuring methazolamide, a glaucoma drug that lowers eye pressure and fluid, reduces seizures, and combats ROS.Formula:C5H2D6N4O3S2Colore e forma:SolidPeso molecolare:242.31L 662583
CAS:L 662583 is a topical inhibitor of carbonic anhydrase.Formula:C13H17ClN2O5S3Purezza:98%Colore e forma:SolidPeso molecolare:412.93hCAI/II-IN-1
CAS:hCAI/II-IN-1 (Compound 3h) is a human carbonic anhydrase I and II (hCA I/II) inhibitor that acts on hCA I (IC50: 0.047 μM) and hCA II (IC50: 0.024 μM).Formula:C18H29N5O3S3Colore e forma:SolidPeso molecolare:459.65hCAI/II-IN-2
CAS:hCAI/II-IN-2 (2b) inhibits hCA I/II (Ki: 40.97 nM, 15.15 nM) and IX (61.88 nM), fights AMS with anti-hypoxic effects, but has low cellular activity.Formula:C12H12N4O5S2Colore e forma:SolidPeso molecolare:356.38hCA IX-IN-2
hCA IX-IN-2 is a highly potent and selective inhibitor of hCA IX, exhibiting an inhibition constant (K I) value of 32.1 nM and demonstrating anti-proliferativeFormula:C23H24N2O4STeColore e forma:SolidPeso molecolare:552.11hCAIX-IN-14
CAS:hCAIX-IN-14 is a potent inhibitor of human CA IX with a K i value of 134.8 nM .Formula:C11H17ClN6O2SColore e forma:SolidPeso molecolare:332.81hCAI/II-IN-3
CAS:"hCAI/II-IN-3 (compound 5b) is a potent dual hCA I/II inhibitor with Ki: 51.25nM (I), 13.15nM (II), helps treat AMS."Formula:C16H18N4O4S2Colore e forma:SolidPeso molecolare:394.47hCAIX-IN-3
CAS:hCAII-IN-3 (7e) selectively inhibits CA II/IX with Kis of 124.2/30.5 nM, showing promise for cancer treatment.Formula:C21H21BrN6O4SColore e forma:SolidPeso molecolare:533.4hCAIX/XII-IN-6
hCAIX/XII-IN-6: Oral carbonic anhydrase inhibitor, targets hCA I/II/IV/IX/XII, aids rheumatoid arthritis research. Ki: 6697/2950/4093/4.1/7.7 nM.Formula:C26H23N3O6S4Colore e forma:SolidPeso molecolare:601.74L-693612 HCl
CAS:L-693612 HCl is an inhibitor of carbonic anhydrase.Formula:C14H25ClN2O5S3Purezza:98%Colore e forma:SolidPeso molecolare:433.01hCAIX/XII-IN-2
CAS:Compound 6a: Selective hCAIX/XII inhibitor; Ki: 30 nM (hCAIX), 3.6 nM (hCAXII); >10,000 nM (hCAI/II).Formula:C19H14N2O4Colore e forma:SolidPeso molecolare:334.33CDK2-IN-12
CAS:CDK2-IN-12 (10b), potent CDK2 inhibitor, IC50: 11.6 μM; inhibits hCA I/II/IX/XII, KI: 3534/638.4/44.3/48.8 nM; anti-cancer properties.Formula:C20H17N9O2SColore e forma:SolidPeso molecolare:447.47Clofenamide
CAS:Clofenamide is a low-ceiling sulfonamide diuretic.Formula:C6H7ClN2O4S2Colore e forma:SolidPeso molecolare:270.71hCAII-IN-1
CAS:hCAII-IN-1 (7f) inhibits CA II/IX with Kis 1.2 nM/113.6 nM, potential for cancer treatment.Formula:C21H21BrN6O4SColore e forma:SolidPeso molecolare:533.4hCAII-IN-2
CAS:hCAII-IN-2 inhibits human carbonic anhydrases I, II, IX, XII with Ki values of 261.4, 3.8, 19.6, 45.2 nM respectively.Formula:C25H18ClN5O4SColore e forma:SolidPeso molecolare:519.96hCAIX/XII-IN-3
CAS:Compound 6q inhibits hCAIX/CAXII; K i : hCAI >10000 nM, hCAII >10000 nM, hCAIX 66.2 nM, hCAXII 4.4 nM.Formula:C20H13F3N2O4Colore e forma:SolidPeso molecolare:402.32Carbonic anhydrase inhibitor 13
CAS:Carbonic anhydrase inhibitor 13 (compound 7) is a potent inhibitor of carbonic anhydrase (CA).Formula:C17H15N5O3S2Colore e forma:SolidPeso molecolare:401.46hCAIX-IN-8
CAS:hCAIX-IN-8, a selective hCAIX inhibitor, IC50: 0.024 μM. Also affects CAII, CAVA (IC50s: 1.99, 1.10 μM), limits cell migration, and induces apoptosis.Formula:C19H16N4O6Colore e forma:SolidPeso molecolare:396.35CDK2-IN-11
CAS:CDK2-IN-11 inhibits CDK2 (IC50: 6.4 μM) and targets hCA II, IX, XII (Ki: 23.4-56.3 nM); suited for cancer research.Formula:C18H14ClN7O2SColore e forma:SolidPeso molecolare:427.87hCAXII-IN-2
CAS:hCAXII-IN-2 is a potent inhibitor of hCA XII (Ki: 84.2 nM) and hCA IX (Ki: 268.5 nM), with low activity on hCA I/II.Formula:C21H18ClN3O4Colore e forma:SolidPeso molecolare:411.84hCA I-IN-2
CAS:hCA I-IN-2 (6d) inhibits hCA I (Ki: 18.8 nM) more selectively over II, IX, XII (Ki: 375.1, 1721, 283.9 nM).Formula:C26H20BrN5O3SColore e forma:SolidPeso molecolare:562.44hCA I-IN-1
CAS:hCA I-IN-1 inhibits hCA I (Ki: 38.3 nM), II (Ki: 716.4 nM), IX (Ki: 940.1 nM), XII (Ki: 192.8 nM).Formula:C27H23N5O4SColore e forma:SolidPeso molecolare:513.57hCAXII-IN-3
CAS:hCAXII-IN-3 (Compound 6o) is a selective inhibitor of human carbonic anhydrase XII (hCAXII) (Ki: 10.0 nM).Formula:C26H20BrN5O3SColore e forma:SolidPeso molecolare:562.44FC11409B
CAS:FC11409B is a CAIX inhibitor, inhibiting breast cancer invasion and metastasis.Formula:C29H23BF4N2O3SColore e forma:SolidPeso molecolare:566.38L-693612
CAS:L-693612 is an inhibitor of carbonic anhydrase.Formula:C14H24N2O5S3Purezza:98%Colore e forma:SolidPeso molecolare:396.55Carbonic anhydrase inhibitor 7
CAS:Potent hCA inhibitor; targets hCA IX, II, XII, I with Ki: 6.5, 7.1, 72.1, 255.8 nM respectively.Formula:C23H17N3O5SColore e forma:SolidPeso molecolare:447.46hCAXII-IN-1
CAS:hCAXII-IN-1 selectively inhibits HCA IX/XII, promising for new cancer drug development.Formula:C20H17NO5Colore e forma:SolidPeso molecolare:351.35hCAI/II-IN-4
CAS:hCAI/II-IN-4 inhibits hCA I & II (Ki: 16.95 & 15.22 nM), hCA IX (Ki: 27.04 nM), has anti-hypoxia benefits and is low-toxic for AMS research.Formula:C15H15N3O5S2Colore e forma:SolidPeso molecolare:381.43hCAIX-IN-5
CAS:hCAIX-IN-5 was a selective hCAIX inhibitor, inhibiting hCAI, hCAII, hCAIV, and hCAIX with Ki values of >10000, >10000, 130.7, and 829.1 nM, respectively.Formula:C18H12FNO3Purezza:99.25%Colore e forma:SolidPeso molecolare:309.29Quinethazone
CAS:Quinethazone is a thiazide diuretic used to treat hypertension. Common side effects include dizziness, dry mouth, nausea, and low potassium levels.Formula:C10H12ClN3O3SColore e forma:Fibrous Crystals From 50% Acetone Physical Description Fibrous Crystals Or White Powder (Ntp 1992)Peso molecolare:289.74hCAIX-IN-10
CAS:"hCAIX-IN-10 (6i) selectively inhibits carbonic anhydrase IX/XII (Ki: 61.5/586.8 nM), markers in tumor cells, affecting acid-base balance."Formula:C28H21N3O3SColore e forma:SolidPeso molecolare:479.55Disulfamide
CAS:Disulfamide: Oral carbonic anhydrase inhibitor, IC50 0.07 μM, diuretic by blocking Na+/HCO3- reabsorption.Formula:C7H9ClN2O4S2Purezza:98.65%Colore e forma:SolidPeso molecolare:284.74hCAIX-IN-7
CAS:hCAIX-IN-7 (6c) selectively inhibits tumor-related isoform hCAIX (KI: 410.6 nM) and weakly affects hCAI/II (KI: >10000 nM).Formula:C18H12FNO3Colore e forma:SolidPeso molecolare:309.29Carbonic anhydrase inhibitor 14
CAS:CA inhibitor 14 blocks hCA I/II/IX/XII (K i of 1203/99.7/9.4/27.7 nM) and CDK2 (IC50: 20.3 μM), showing antitumor effects.Formula:C18H17N7O2SColore e forma:SolidPeso molecolare:395.44hCAXII-IN-5
CAS:hCAXII-IN-5, or compound 6o, is a potent, selective hCAXII inhibitor with Ki values: hCAI & II >10000, hCAIX 286.1, hCAXII 1.0 nM.Formula:C23H22N2O4Colore e forma:SolidPeso molecolare:390.43hCAIX-IN-6
CAS:6B and 14g inhibit tumor-associated HCA IX with low nanomolar potency; 6K targets HCA XII. All are potential cancer drug leads.Formula:C18H12N2O4SColore e forma:SolidPeso molecolare:352.36DTP348
CAS:DTP348: Oral carbonic anhydrase IX inhibitor & hypoxic cell radiosensitizer with sulfamide & 5-nitroimidazole components.Formula:C6H11N5O4SColore e forma:SolidPeso molecolare:249.25Carbonic anhydrase inhibitor 11
CAS:Potent carbonic anhydrase inhibitor VI targets CA II, IX, XII with Ki: 40, 39, 900 nM respectively.Formula:C19H15F3N4O3S2Colore e forma:SolidPeso molecolare:468.47hCAIX/XII-IN-4
CAS:hCAIX/XII-IN-4 inhibits CAIX/XII with Ki: 4.5 nM (CAXII), 23.6 nM (CAIX), and >10000 nM (CAI/CAII).Formula:C20H16N2O5Colore e forma:SolidPeso molecolare:364.35HCAIX-IN-2
CAS:HCAIX-IN-2 (compound 9d) is a selective inhibitor of carbonic anhydrase and acts on hCA IX (Ki: 24.6 nM) and hCA XII (Ki: 45.3 nM).Formula:C19H16N8O4SColore e forma:SolidPeso molecolare:452.45GV2-20
CAS:GV2-20 is an effective carbonic anhydrase 2 inhibitors.Formula:C15H13N3O6Purezza:98%Colore e forma:SolidPeso molecolare:331.28L 645151
CAS:L 645151 is an inhibitor of lipophilic CA.Formula:C12H14N2O4S2Colore e forma:SolidPeso molecolare:314.38hCAII-IN-9
CAS:hCAII-IN-9 inhibits hCA II/IX/XII with IC50s of 1.18, 0.17, 2.99 μM; not BBB permeable.
Formula:C15H16ClN3O5S2Purezza:98.63%Colore e forma:SolidPeso molecolare:417.89hCAI/II-IN-6
CAS:hCAI/II-IN-6 is a selective and orally active inhibitor of human carbonic anhydrase (CA).Formula:C19H24N4O3SPurezza:98.49%Colore e forma:SolidPeso molecolare:388.48
