Anidrasi carbonica
L'anidrasi carbonica è un enzima che catalizza la conversione reversibile del diossido di carbonio e acqua in bicarbonato e protoni. Questo enzima svolge un ruolo cruciale nel mantenimento dell'equilibrio acido-base, nella respirazione e nel trasporto di anidride carbonica nel sangue. Gli inibitori dell'anidrasi carbonica sono utilizzati nel trattamento del glaucoma, dell'epilessia e del mal di montagna, nonché nella ricerca sull'omeostasi acido-base e lo scambio gassoso. Presso CymitQuimica, offriamo una gamma di inibitori dell'anidrasi carbonica e reagenti di alta qualità per supportare la tua ricerca in enzimologia, fisiologia respiratoria e sviluppo terapeutico.
Trovati 197 prodotti di "Anidrasi carbonica"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Sultiame
CAS:Sultiame is an inhibitor of carbonic anhydrase. Sultiame can be used in antiepileptic research.Formula:C10H14N2O4S2Purezza:99.91%Colore e forma:SolidPeso molecolare:290.36Carbonic anhydrase inhibitor 6
CAS:Carbonic anhydrase inhibitor 6 is an hCA inhibitor that inhibits hCA IX, hCA II, hCA XII, and hCA I. It is used in the study of lupus erythematosus.Formula:C26H25N3O5SPurezza:98.81%Colore e forma:SolidPeso molecolare:491.56Ref: TM-T63305
1mg167,00€2mg246,00€5mg411,00€10mg562,00€25mg867,00€50mg1.121,00€100mg1.425,00€200mg1.882,00€Carbonic anhydrase inhibitor 12
CAS:CA Inhibitor 12 strongly blocks CA II (K_i 1.72 nM), also inhibits CA I (271 nM), shows anticancer effects.Formula:C27H22BrN5O5S2Purezza:98%Colore e forma:SolidPeso molecolare:640.53hCAIX-IN-16
CAS:hCAIX-IN-16 (Compound 12d), an inhibitor of hCA IX, exhibits inhibition constants (K i) of 190.0 nM for hCA IX and 187.9 nM for hCA XII.Formula:C20H20N8O2SPurezza:98%Colore e forma:SolidPeso molecolare:436.49COX-2-IN-30
CAS:COX-2-IN-30, a benzenesulfonamide derivative, is an orally active, dual inhibitor of cyclooxygenase-2 (COX-2; IC50 = 49 nM) and cyclooxygenase-1 (COX-1; IC50 =Formula:C17H16N6O3SPurezza:98%Colore e forma:SolidPeso molecolare:384.41CAXII-IN-1
CAS:CAXII-IN-1, antitumor, selectively inhibits CA XII with Ki of 3.8 nM for hCA XII and 56 nM for hCA IX.Formula:C13H7Cl2NO3SColore e forma:SolidPeso molecolare:328.17Sezolamide hydrochloride
CAS:Sezolamide hydrochloride is a potent topical carbonic anhydrase inhibitor.Formula:C11H19ClN2O4S3Colore e forma:SolidPeso molecolare:374.93hCAIX-IN-15
CAS:hCAIX-IN-15 is a potent inhibitor of human carbonic anhydrase IX (hCA IX) with an inhibition constant (Ki) of 38.8 nM, exhibiting broad-spectrum anticancerFormula:C18H14FN7O2SPurezza:98%Colore e forma:SolidPeso molecolare:411.41hCAIX/XII-IN-8
CAS:hCAIX/XII-IN-8 (compound 3g) is a potent inhibitor of the human carbonic anhydrases (CAs) IX and XII, with inhibition constants (K i) of 8.5 nM for CA IX and 6.Formula:C16H13Cl2N5O3SPurezza:98%Colore e forma:SolidPeso molecolare:426.28N-Desethyl Brinzolamide oxalate
CAS:N-Desethyl Brinzolamide oxalate functions as a dual inhibitor targeting Carbonic anhydrase II and Carbonic anhydrase IV, exhibiting inhibitory concentrations (IC50) of 1.28 nM and 128 nM, respectively [1].Formula:C12H19N3O9S3Colore e forma:SolidPeso molecolare:445.49ALP/Carbonic anhydrase-IN-1
CAS:Compound 1e, also known as ALP/Carbonic anhydrase-IN-1, is a dual inhibitor targeting both carbonic anhydrase (CA) isozymes II, IX, and XII, as well as alkalineFormula:C15H16N2Purezza:98%Colore e forma:SolidPeso molecolare:224.3Sezolamide
CAS:Sezolamide is a carbonic anhydrase inhibitor.Formula:C11H18N2O4S3Colore e forma:SolidPeso molecolare:338.47hCA XII/II/IX-IN-1
hCA XII/II/IX-IN-1 inhibits hCA I/II/IX/XII (IC50: 2.6, 0.004, 0.005, 0.001 μM) with anticancer properties.Formula:C25H34N4O7SColore e forma:SolidPeso molecolare:534.63Carbonic anhydrase inhibitor 10
CA inhibitor 10 targets MCF-7 cells, IC50: 11.9 μM; potent h CA IX inhibitor, Ki: 6.2 nM. Anti-cancer research.Formula:C14H17N5O3SColore e forma:SolidPeso molecolare:335.38β-Glucuronidase/hCAII-IN-1
CAS:β-Glucuronidase/hCAII-IN-2 (Compound 12e) is a compound that effectively inhibits both β-glucuronidase and human Carbonic Anhydrase II (hCA II), exhibiting IC50Formula:C30H21NO9Colore e forma:SolidPeso molecolare:539.49NSC 828467
NSC 828467 is one of the top five CA-IX inhibitors with significant in vitro anticancer activity (IC50: 27.2 nM).Formula:C21H19N9O2SColore e forma:SolidPeso molecolare:461.5hCA VB-IN-1
hCA VB-IN-1 (compound 15) is a potent and selective inhibitor of hCA VB (carbonic anhydrase) with a KI of 515.7 nM [1].Formula:C9H13N3O4SColore e forma:SolidPeso molecolare:259.28CAII-IN-2
CAII-IN-2 (3g): potent, selective CA-II inhibitor; IC50-12.1 μM for bovine CA-II; valuable in CA-related disorder research.Formula:C18H19BrN4SColore e forma:SolidPeso molecolare:403.34Carbonic anhydrase inhibitor 5
Potent hCA inhibitor: targets hCA II, IX & XII with IC50s of 42.9, 47.6, & 6.7 nM respectively.Formula:C24H20ClN3O3SColore e forma:SolidPeso molecolare:465.95Carbonic anhydrase inhibitor 9
Carbonic anhydrase inhibitor 9 targets hCA II and IX with Ki of 56.4 and 56.9 nM respectively; shows antiproliferative activity.Formula:C22H20BrN5O4SColore e forma:SolidPeso molecolare:530.39hCAII-IN-5
CAS:hCAII-IN-5 (compound 12h) is a potent, selective inhibitor of human carbonic anhydrase II (hCA II) with an inhibition constant (IC50) of 4.55 µM [1].Formula:C29H18N2O7Colore e forma:SolidPeso molecolare:506.46hCAII-IN-3
<p>hCAII-IN-3 inhibits key hCA isoforms with Ki: hCA I (403.8 nM), hCA II (5.1 nM), hCA IX (10.2 nM), hCA XII (5.2 nM); shows anticancer potential.</p>Formula:C17H21N3O3SColore e forma:SolidPeso molecolare:347.43Perfluorohexane sulfonamide
CAS:Perfluorohexane sulfonamide (FHxSA) serves as an inhibitor of carbonic anhydrase (CA), effectively inhibiting bovine CA and human CAII with IC50 values of 0.122 and 1.38 μM, respectively. Additionally, it acts as a delayed-action insecticide for controlling red imported fire ants (Solenopsis invicta). Furthermore, Perfluorohexane sulfonamide is considered a potential environmental pollutant.Formula:C6H2F13NO2SColore e forma:SolidPeso molecolare:399.13AChE/CA I-IN-1
AChE/CA I-IN-1 (Compound 2g) acts as an inhibitor for both AChE and hCA I, with Ki values of 1.85 µM and 0.53 µM, respectively. It has shown potential applications in the research of Alzheimer's disease, glaucoma, and epilepsy.Formula:C14H19NO6SColore e forma:SolidPeso molecolare:329.37hCAIX/XII-IN-15
CAS:hCAIX/XII-IN-15 (Compound 17β) is an inhibitor of hCA IX and hCA XII, exhibiting Ki values of 0.42 and 4.37 μM, respectively. It demonstrates a pro-apoptotic effect in multiple myeloma cells.Formula:C17H18O4SColore e forma:SolidPeso molecolare:318.387Carbonic anhydrase inhibitor 4
CA inhibitor 4, photoprobe; targets hCA I-XIV; Ki: 640-1166 nM.Formula:C21H18N2O4SColore e forma:SolidPeso molecolare:394.44CA IX-IN-1
CA IX-IN-1 (compound 12g) is a potent and highly selective hCA IX inhibitor (IC50: 7 nM) that exhibits antitumour effects.Formula:C16H22N4O8SColore e forma:SolidPeso molecolare:430.43Carbonic anhydrase inhibitor 16
CAS:Carbonic anhydrase inhibitor 16 (compound 1) is a CA I/CA II inhibitor with potential antiviral activity, used in virus infection studies.Formula:C14H10N2O4SPurezza:99.65%Colore e forma:SolidPeso molecolare:302.31CA IX-IN-3
CAS:CAIX-IN-3 (Compound 27) is a selective and potent inhibitor of carbonic anhydrase IX (CAIX), with an IC50 of 0.48 nM.Formula:C21H19N5O4S2Colore e forma:SolidPeso molecolare:469.537CAII-IN-1
CAII-IN-1 (3n) is a selective bovine CA-II inhibitor with 10.3 μM IC50, used in carbonic anhydrase disorder studies.Formula:C19H21FN4SColore e forma:SolidPeso molecolare:356.46hCAVII/IX-IN-1
CAS:hCAVII/IX-IN-1 (compound 4) functions as an inhibitor of hCAVII/IX, exhibiting Ki values of 56.5 nM and 38.2 nM, respectively. It is applicable in the field of cancer research.Formula:C7H7N3O2S2Colore e forma:SolidPeso molecolare:229.279CAII-IN-3
CAII-IN-3, a thiosemicarbazone, potently inhibits CA-II with an IC50 of 13.4 μM.Formula:C18H18F2N4SColore e forma:SolidPeso molecolare:360.42β-Glucuronidase/hCAII-IN-2
β-Glucuronidase/hCAII-IN-2 is a potent inhibitor of β-glucuronidase and hCA II, and their IC50 values were 670.7 μM and 21.77 μM, respectively.Formula:C31H23NO8Colore e forma:SolidPeso molecolare:537.52Carbonic anhydrase inhibitor 2
CAS:Compound 7c inhibits carbonic anhydrase II, lowering intraocular pressure in glaucomatous rabbits.Formula:C12H16N4O6SColore e forma:SolidPeso molecolare:344.34hCAII-IN-4
CAS:hCAII-IN-4 (Compound 12j) is a potent inhibitor of human carbonic anhydrase II (hCA II), exhibiting an inhibitory concentration (IC50) of 7.78 μM.Formula:C31H23NO9Colore e forma:SolidPeso molecolare:553.52Carbonic anhydrase inhibitor 3
Carbonic anhydrase inhibitor 3 (compound 11g) is an inhibitor of carbonic anhydrase II that reduces the intraocular pressure in glaucomatous rabbits [1].Formula:C15H17N3O3SColore e forma:SolidPeso molecolare:319.38Valerate sodium
CAS:<p>Valerate sodium is a potential Carbonic anhydrase 1/2 inhibitor for biochemical experiments.</p>Formula:C5H9NaO2Purezza:99.84%Colore e forma:SolidPeso molecolare:124.11hCAI/II/XII-IN-1
CAS:<p>hCAI/II/XII-IN-1 (compound 7) is an inhibitor of human carbonic anhydrases hCAI, hCAII, and hCAXII, with Ki values of 78.5 nM, 9.1 nM, 605 nM, 7.7 nM, and 3.7 nM.</p>Formula:C12H12N2O2SColore e forma:SolidPeso molecolare:248.301hCAIX-IN-20
CAS:hCAIX-IN-20 (compound APBS-5m) is a potent inhibitor of carbonic anhydrase IX (hCA IX), with a Ki of 2.7 nM, playing a significant role in cancer research.Formula:C19H13Cl2N5O4S2Peso molecolare:510.37Carbonic anhydrase inhibitor 17
CAS:Carbonic anhydrase inhibitor 17 (compound 7c) is a pyrazine-based sulfonamide that acts as a carbonic anhydrase II inhibitor, with an IC50 value of 0.63 nM.Formula:C18H15ClN4O3S2Peso molecolare:434.92Carbonic anhydrase inhibitor 19
CAS:Carbonic anhydrase inhibitor19 (compound 26a) targets glaucoma-associated isozymes hCA II and hCA XII, with inhibition constants (Kis) of 9.4 nM and 6.7 nM, respectively. This compound is effective in reducing intraocular pressure.Formula:C23H25N3O6S2Peso molecolare:503.59α-Glucosidase-IN-63
CAS:α-Glucosidase-IN-63 (Compound 4d) serves as an α-Glucosidase inhibitor with an IC 50 value of 0.44 μM. Additionally, it exhibits inhibitory activity against hCA II, demonstrating a K i of 7.0 nM. The compound is also effective when administered orally. [1]Formula:C16H12FN3O3S2Colore e forma:SolidPeso molecolare:377.41EGFR/VEGFR2-IN-2
EGFR/VEGFR2-IN-2 (compound 4b) serves as a dual inhibitor of VEGFR-2 and EGFR.Formula:C24H15FO3Colore e forma:SolidPeso molecolare:370.37Sulclamide
CAS:Sulclamide, a sulfamoylbenzoic acid derivative, exhibits diuretic activity and functions as an inhibitor of carbonic anhydrase [1].Formula:C7H7ClN2O3SColore e forma:SolidPeso molecolare:234.664-Acetylphenylboronic acid
CAS:4-Acetylphenylboronic acid acts as an effective inhibitor targeting carbonic anhydrase II (CAII), displaying inhibitory concentrations (IC50) of 246 μM for bovine CAII (bCA II) and 281.40 μM for human CAII (hCA II).Formula:C8H9BO3Colore e forma:SolidPeso molecolare:163.97O-Desmethyl Brinzolamide hydrochloride
CAS:O-Desmethyl Brinzolamide hydrochloride (compound 6a), a potent metabolite derived from Brinzolamide, serves as a carbonic anhydrase (CA) inhibitor. It exhibits a dissociation constant (Kd) of 0.136 nM for CA II and an inhibitory concentration (IC50) of 165 nM for CA IV [1].Formula:C11H20ClN3O5S3Colore e forma:SolidPeso molecolare:405.94Carbonic anhydrase inhibitor 8
R-13, a carbonic anhydrase inhibitor, has Ki of 60.7 nM (hCA I), 320.7 nM (hCA II), and 2298 nM (hCA IV).Formula:C20H25N3O4SColore e forma:SolidPeso molecolare:403.5
