FAAH
La Fatty Acid Amide Hydrolase (FAAH) è un enzima che degrada gli amidi degli acidi grassi, inclusi gli endocannabinoidi come l'anandamide. Questi composti sono coinvolti nella regolazione del dolore, dell'umore, dell'appetito e della memoria. L'inibizione della FAAH può aumentare i livelli di queste molecole di segnalazione, offrendo potenziali benefici terapeutici per il dolore, l'ansia e le malattie neurodegenerative. Presso CymitQuimica, offriamo una selezione di inibitori della FAAH per supportare la tua ricerca in neuroscienze, gestione del dolore e segnalazione endocannabinoide.
Trovati 65 prodotti di "FAAH"
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N-Benzyllinolenamide
CAS:N-Benzyllinolenamide is a natural product. It is an inhibitor of fatty acid amide hydrolase (FAAH, IC50 of 41.8 μM).Formula:C25H37NOPurezza:98.7% - 99.92%Colore e forma:SolidPeso molecolare:367.57PF-04457845
CAS:PF-04457845 is a greatly and effctive FAAH inhibitor, and for hFAAH(IC50=7.2±0.63 nM) and rFAAH(IC50=7.4±0.62 nM).Formula:C23H20F3N5O2Purezza:>99.99%Colore e forma:SolidPeso molecolare:455.43JNJ-1661010
CAS:JNJ-1661010 (Takeda-25) is an effective and specific FAAH inhibitor (IC50: 10/ 12 nM for rat/human), shows >100-fold selectivity for FAAH-1 than FAAH-2.Formula:C19H19N5OSPurezza:99.79% - 99.97%Colore e forma:SolidPeso molecolare:365.45BIA 10-2474
CAS:BIA 10-2474 is a long-acting reversible inhibitor of FAAH that increases levels of the neurotransmitter anandamide in the nervous system.Formula:C16H20N4O2Purezza:99.27%Colore e forma:SolidPeso molecolare:300.36URB-597
CAS:URB-597 (FAAH Inhibitor II) is an effective, orally bioavailable FAAH inhibitor (IC50: 4.6 nM), and no effect on other cannabinoid-related targets.Formula:C20H22N2O3Purezza:97.20% - 98.24%Colore e forma:SolidPeso molecolare:338.44-Nonylphenylboronic acid
CAS:<p>4-Nonylphenylboronic acid is a inhibitor of FAAH.</p>Formula:C15H25BO2Purezza:97.63%Colore e forma:SolidPeso molecolare:248.17MAGL-IN-4
CAS:<p>MAGL-IN-4 (His121 ARG57) is one of the monoacylglycerol lipase (MAGL) inhibitors in central nervous system-related diseases.</p>Formula:C18H21ClN2O4Purezza:99.79%Colore e forma:SolidPeso molecolare:364.82N-Benzylpalmitamide
CAS:N-Benzylpalmitamide (Macamide 1) inhibits fatty acid amide hydrolase (FAAH) in a time-dependent manner and could potentially offer a good alternative for theFormula:C23H39NOPurezza:97.08% - 99.77%Colore e forma:SolidPeso molecolare:345.56FAAH-IN-8
CAS:<p>FAAH-IN-8 (compound 11) is a competitive inhibitor of FAAH with an IC50 of 6.7 nM and a Ki of 5 nM. It exhibits high blood-brain permeability and a significant antioxidant profile without neurotoxicity [1].</p>Formula:C18H14N4OColore e forma:SolidPeso molecolare:302.33AKU-005
CAS:AKU-005 is a dual inhibitor of FAAH and MAGL, exhibiting IC50 values of 63 nM and 389 nM against rat and human FAAH, respectively. This compound has potential for researching trigeminal nociceptive hypersensitivity.Formula:C20H21N5OColore e forma:SolidPeso molecolare:347.41JNJ-40413269
CAS:JNJ-40413269 inhibits FAAH, engages central targets, and is effective in rat neuropathic pain.Formula:C19H15ClF3N3OColore e forma:SolidPeso molecolare:393.79SA57
CAS:SA57 is a potent, selective inhibitor of FAAH(IC50s of 3.2 nM and 1.9 nM for mouse and human FAAH).Formula:C17H23ClN2O3Purezza:98%Colore e forma:SolidPeso molecolare:338.83Acetylhydrolase-IN-1
CAS:Acetylhydrolase-IN-1 is an inhibitor of the esterase 1-Alkyl-2-acetylglycerophosphocholine (Alkylacetyl-GPC: acetylhydrolase).Formula:C23H48NO7PPurezza:98%Colore e forma:SolidPeso molecolare:481.6OL-135
CAS:<p>OL-135: CNS-accessible, potent, selective FAAH inhibitor with analgesic effects in animals, no motor impairment.</p>Formula:C21H22N2O2Colore e forma:SolidPeso molecolare:334.41FAAH-IN-7
FAAH-IN-7: Reversible FAAH inhibitor, IC50=8.29 nM, reduces oxidative stress, neuroprotective in neuroinflammation.Formula:C26H29N3O4Colore e forma:SolidPeso molecolare:447.53FAAH-IN-5
CAS:FAAH-IN-5 (Compound 7) selectively, irreversibly inhibits FAAH (IC50: 10.5 nM) with low PAMPA permeability.Formula:C21H19N3O6SColore e forma:SolidPeso molecolare:441.46URB-694
CAS:URB-694 is a fatty acid amide hydrolase (FAAH) inhibitor.Formula:C19H21NO3Colore e forma:SolidPeso molecolare:311.37MDPD
CAS:MDPD boosts AtFAAH, the enzyme degrading NAEs in Arabidopsis, reducing NAE 12:0's growth inhibition.Formula:C21H19N3O3Colore e forma:SolidPeso molecolare:361.39TAK 21d
CAS:Potent FAAH inhibitorFormula:C19H17F2N7OPurezza:98%Colore e forma:SolidPeso molecolare:397.38Arachidonyl serotonin
CAS:Dual FAAH inhibitor/TRPV1 antagonistFormula:C30H42N2O2Purezza:98%Colore e forma:SolidPeso molecolare:462.67
