PPAR
I recettori attivati dai proliferatori dei perossisomi (PPARs) sono un gruppo di proteine recettori nucleari che funzionano come fattori di trascrizione regolando l'espressione di geni coinvolti nel metabolismo, in particolare lo stoccaggio degli acidi grassi e il metabolismo del glucosio. Gli inibitori dei PPARs sono strumenti importanti per lo studio dei disturbi metabolici come il diabete, l'obesità e le malattie cardiovascolari. Questi inibitori possono modulare il metabolismo dei lipidi, la sensibilità all'insulina e l'infiammazione, rendendoli preziosi nella ricerca terapeutica. Presso CymitQuimica, offriamo una gamma di inibitori dei PPARs per supportare la tua ricerca in malattie metaboliche, endocrinologia e sviluppo di farmaci.
Trovati 180 prodotti per "PPAR".
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Rosiglitazone hydrochloride
CAS:Rosiglitazone hydrochloride (BRL-49653 HCl) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.Formula:C18H20ClN3O3SPurezza:99.63% - 99.94%Colore e forma:White SolidPeso molecolare:393.888E0924G
CAS:E0924G is an orally active PPARδ agonist with an EC50 of 2.82 μM. It enhances the upregulation of osteoprotegerin (OPG) expression, with an EC50 of 0.29 μM. E0924G reduces RANKL-induced osteoclast differentiation and inhibits F-actin ring formation in RAW264.7 macrophages. Additionally, E0924G modulates bone density and bone loss in models of ovariectomy (OVX) and age-related osteoporosis.Formula:C12H12N2O3Colore e forma:SolidPeso molecolare:232.24Prostaglandin A3
CAS:Prostaglandin A3 is a non-enzymatic dehydration product of prostaglandin E3 (PGE3). It demonstrates significant affinity for canine EP2 and EP4 receptors with IC50 values of 120 nM and 20 nM, respectively. For human PPARγ, Prostaglandin A3 has a Ki value of 188 μM.Formula:C20H28O4Peso molecolare:332.43(±)-CBCQ
CAS:(±)-CBCQ, an oxidation product of cannabidiol, exhibits an EC50 value of 14.7 μM for the activation of peroxisome proliferator-activated receptor γ (PPAR-γ).Formula:C21H28O3Colore e forma:SolidPeso molecolare:328.45Anti-obesity agent 1
Compound 4 (Anti-obesity agent 1) demonstrates potential for enhanced lipolysis, highlighting its anti-obesity characteristics.Formula:C21H22N2O6Colore e forma:SolidPeso molecolare:398.409PPARγ agonist 16
CAS:PPARγ agonist16 (Compound 4G) is a PPARγ agonist that competitively binds to the ligand-binding domain (LBD) of PPARγ with an IC50 of 1790 nM. It reduces ear swelling in mouse models and exhibits antihyperglycemic activity in mice with Streptozotocin-induced diabetes.Formula:C19H14BrNO4SColore e forma:SolidPeso molecolare:432.29Fmoc-Leu-OH-D10
CAS:Fmoc-Leu-OH-D10 is a deuterated compound of Fmoc-Leu-OH. Fmoc-Leu-OH (T8638) has a CAS number of 35661-60-0. NPC 15199 is an anti-inflammatory agent.Formula:C21D10H13NO4Peso molecolare:363.47Tesaglitazar
CAS:Tesaglitazar is a potent and selective peroxide PPARα / γ receptor dual agonist with a more potent affinity for PPARγ than PPARα, The EC50 values for rat PPARαFormula:C20H24O7SPurezza:97.79% - 99.95%Colore e forma:SolidPeso molecolare:408.47Inolitazone dihydrochloride
CAS:Inolitazone dihydrochloride is an effective, high-affinity PPARγ agonist; its biological activity is dependent on PPARγ (IC50:0.8 nM) to inhibit cell growth.Formula:C27H28Cl2N4O4SColore e forma:SolidPeso molecolare:575.507GW 9578
CAS:GW 9578 is a PPARα agonist with potent lipid-lowering activity for the study of psoriasis, arthritis, alopecia, asthma and type I diabetes.Formula:C26H34F2N2O3SPurezza:98%Colore e forma:SolidPeso molecolare:492.62Peliglitazar racemate
CAS:Peliglitazar racemate(BMS 426707-01 racemate) is the racemate of Peliglitazar.Peliglitazar racemate may be used as a potential antidiabetic and anti-obesityFormula:C30H30N2O7Purezza:97.75%Colore e forma:SolidPeso molecolare:530.57BVT.13
CAS:BVT.13 is an orally active selective PPARγ agonist with antidiabetic activity comparable to rosiglitazone, supporting research in metabolic regulation.Formula:C18H11Cl2N3O4Purezza:98.59%Colore e forma:White SolidPeso molecolare:404.2FTX-6746
CAS:FTX-6746 is an orally active and selective PPARG reverse inhibitor with anticancer activity. It can be used in research on urothelial carcinoma.Formula:C16H7ClF2N2OPurezza:98.68%Colore e forma:SolidPeso molecolare:316.69GSK376501A
CAS:GSK376501A is a selective and effective modulator of peroxisome proliferator-activated receptor γ (PPARγ) for the study of type 2 diabetes.Formula:C32H37NO6Purezza:97.71% - >99.99%Colore e forma:White SolidPeso molecolare:531.64Pparδ agonist 2
CAS:Pparδ agonist 2 is an agonist of PPARδ.Formula:C20H18F3N3O3SPurezza:98%Colore e forma:SolidPeso molecolare:437.44Daltroban
CAS:Daltroban (SKF 96148) is a specific thromboxane A2 (TXA2) receptor antagonist.Formula:C16H16ClNO4SPurezza:99.66%Colore e forma:SolidPeso molecolare:353.821FX-909
CAS:FX-909 is a covalent peroxisome proliferator-activated receptor gamma ( PPARG ) inverse agonist. FX-909 can be used for the research of cancer .Formula:C17H10F2N2O3SPurezza:99.53%Colore e forma:White SolidPeso molecolare:360.33Saroglitazar
CAS:Saroglitazar (Lipaglyn) is an agonist of PPAR with EC50 values of 0.65 pM and 3 nM for PPARα and PPARγ.Formula:C25H29NO4SPurezza:98.51%Colore e forma:SolidPeso molecolare:439.567PPARα-MO-1
CAS:PPARα-MO-1 is a potent modulator of PPARα.Formula:C27H37NO5Purezza:98%Colore e forma:SolidPeso molecolare:455.59LG100754
CAS:LG100754 (UVI 2112) is an insulin sensitizer and RXR modulator, antagonizing RXR homodimers while agonizing RXR:PPARα/γ heterodimers.Formula:C26H36O3Colore e forma:White SolidPeso molecolare:396.56
