Sintasi degli acidi grassi
La sintasi degli acidi grassi (FAS) è un complesso multi-enzimatico responsabile della sintesi degli acidi grassi a catena lunga. La sovraespressione di FAS è associata a vari disturbi metabolici, tra cui obesità, diabete e cancro. L'inibizione di FAS può ridurre la biosintesi lipidica e indurre apoptosi nelle cellule tumorali, rendendola un obiettivo promettente per la terapia del cancro e la ricerca sulle malattie metaboliche. Presso CymitQuimica, offriamo una varietà di inibitori di FAS per supportare la tua ricerca in oncologia, metabolismo e sviluppo terapeutico.
Trovati 40 prodotti per "Sintasi degli acidi grassi".
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PF429242 dihydrochloride
CAS:PF429242 dihydrochloride can reversibly inhibit S1P (IC50 of 175 nM).Formula:C25H37Cl2N3O2Purezza:99.68%Colore e forma:White ViscousPeso molecolare:482.49FASN-IN-3
CAS:FASN-IN-3 is an inhibitor of fatty acid synthase (FASN).Formula:C24H24N4OPurezza:97.41%Colore e forma:SolidPeso molecolare:384.4736Denifanstat
CAS:Denifanstat (FASN-IN-2) is a FASN inhibitor with selective and oral activity. Denifanstat has been used in studies of steatohepatitis. Cost effective and quality assured.Formula:C27H29N5OPurezza:98.33% - 99.35%Colore e forma:SolidPeso molecolare:439.5521trans-C75
CAS:trans-C75 ((±)-C75) is an enantiomer of C75. C75 is an inhibitor of fatty-acid synthase (FASN).Formula:C14H22O4Purezza:98.88% - 99.57%Colore e forma:White To Off-White SolidPeso molecolare:254.3221IPI-9119
CAS:IPI-9119 is an orally active, selective and irreversible FASN inhibitor (IC50 = 0.3 nM).Formula:C24H19F2N5O5Purezza:99.81%Colore e forma:SolidPeso molecolare:495.435Lipid Metabolism Compound Library
A unique collection of xnum compounds targeting lipid metabolism, can be used for high-throughput screening (HTS) and high-content screening (HCS).Colore e forma:Odour SolidFASN-IN-4 tosylate
CAS:FASN-IN-4 tosylate: Fatty acid synthase inhibitor, IC50 10 nM; blocks SARS-CoV-2, EC50 18.6 nM.Formula:C33H35N3O7S2Colore e forma:SolidPeso molecolare:649.777CTL-12
CTL-12, a fatty acid synthase (FASN) inhibitor (IC50: 2.5 μM), induces apoptosis and disrupts the cell cycle at the Sub-G1/S phase.Formula:C22H21ClN4O4Colore e forma:SolidPeso molecolare:440.88Fasnall HCl
Fasnall HCl is a selective FASN inhibitor that acts through its co-factor binding sites.Formula:C19H23ClN4SPurezza:99.97%Colore e forma:SolidPeso molecolare:374.93C75
CAS:C75 is an inhibitor synthetic fatty-acid synthase (FASN) and inhibits prostate cancer cells PC3 (IC50: 35 μM).Formula:C14H22O4Purezza:98.84% - >99.99%Colore e forma:White SolidPeso molecolare:254.32FASN/SCD-IN-1
FASN/SCD-IN-1 is a Silybin derivative and an orally active inhibitor of fatty acid synthase (FASN) and stearoyl-CoA desaturase (SCD). In vitro, FASN/SCD-IN-1 demonstrates the ability to inhibit lipid deposition, reduce the transcription levels of FASN and SCD, and exhibits antioxidant, anti-inflammatory, and antifibrotic activities. It shows significant hepatoprotective effects in rat models of acute liver injury and improves pathological features such as steatosis, inflammation, and fibrosis in a mouse model of myeloproliferative-associated steatohepatitis (MASH). FASN/SCD-IN-1 can be used for MASH research.Colore e forma:Odour SolidHpFabZ Inhibitor 1
CAS:HpFabZ Inhibitor 1 (compound 1) is a selective inhibitor of HpFabZ (H. pyloriFormula:C13H9Br2N3O3Purezza:99.30%Peso molecolare:415.037ACSS2-IN-2
CAS:MTB-9655 inhibits ACSS2 with 3.8 nM IC50, useful in research of viral, metabolic, neuropsychiatric diseases, inflammation, and cancer.Formula:C21H19F2N3O4Purezza:99.5%Colore e forma:SoildPeso molecolare:415.3901FASN Protein, Human, Recombinant (His)
FASN Protein, Human, Recombinant (His) is expressed in E.Colore e forma:Lyophilized PowderPeso molecolare:35.26 kDa (predicted)Anti-FASN Antibody (6U56)
Anti-FASN Antibody (6U56) is an antibody targeting FASN. Anti-FASN Antibody (6U56) can be used in ELISA, IF, FCM.Colore e forma:Odour LiquidGSK2194069
CAS:GSK2194069: Fatty acid synthase inhibitor, β-keto reductase-specific, IC50 7.7 nM, hampers cancer cell proliferation.Formula:C25H24N4O3Purezza:98.75% - 99.84%Colore e forma:Yellow SolidPeso molecolare:428.48BI 99179
CAS:BI 99179 is a selective and potent inhibitor of type I fatty acid synthase (FAS), a tool compound for targeting FAS for cancer research.Formula:C23H25N3O3Purezza:98.73%Colore e forma:SolidPeso molecolare:391.4629FASN Protein, Mouse, Recombinant (His)
FASN Protein, Mouse, Recombinant (His) is expressed in E.Purezza:≥ 95 % as determined by SDS-PAGE. - ≥ 95 % as determined by SDS-PAGE.Colore e forma:White Lyophilized PowderPeso molecolare:34.23 kDa (predicted)FT113
CAS:FT113 is a novel potent inhibitor of fatty acid synthase (fasn, IC50 : 213 nM),and exhibits anti-cancer activityFormula:C22H20FN3O4Purezza:97.05%Colore e forma:SolidPeso molecolare:409.4103PF 429242
CAS:PF-429242 inhibits SREBP site 1 protease selectively (IC50: 0.175 μM); reduces cholesterol synthesis in CHO cells (IC50: 0.53 μM).Formula:C25H35N3O2Purezza:99.27%Colore e forma:SolidPeso molecolare:409.56
