CymitQuimica logo
Deidrogenasi

Deidrogenasi

Le deidrogenasi sono enzimi coinvolti nelle reazioni di ossidoriduzione delle vie metaboliche, svolgendo un ruolo centrale nella produzione di energia e nella respirazione cellulare. Questi enzimi sono cruciali per processi come il ciclo dell'acido citrico, la glicolisi e l'ossidazione degli acidi grassi. Gli inibitori delle deidrogenasi sono strumenti importanti nello studio delle malattie metaboliche, del cancro e dello stress ossidativo. Presso CymitQuimica, offriamo una selezione completa di inibitori delle deidrogenasi per supportare la tua ricerca in metabolismo, biologia del cancro e biochimica.

Trovati 299 prodotti di "Deidrogenasi"

Ordinare per

Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
prodotti per pagina.
  • CAY10566

    CAS:
    CAY10566 is a potent SCD1 inhibitor, orally bioavailable, with IC50s: HepG2 cells, 7.9nM; mouse, 4.5nM; human, 26nM.
    Formula:C18H17ClFN5O2
    Purezza:99.5% - 99.54%
    Colore e forma:Solid
    Peso molecolare:389.81
  • SCD1 inhibitor-4

    CAS:
    <p>SCD1 inhibitor-4 is stearoylCoA desaturase-1 (SCD1) inhibitor. SCD1 inhibitor-4 can be used for the research of diabetes.</p>
    Formula:C17H16F3N5O
    Purezza:99.71%
    Colore e forma:Solid
    Peso molecolare:363.34
  • KPLH1130

    CAS:
    <p>KPLH1130, a PDK inhibitor, boosts glucose tolerance and reduces inflammation in high-fat diet mice.</p>
    Formula:C15H13N3O3
    Purezza:99.07%
    Colore e forma:Solid
    Peso molecolare:283.28
  • GSK2837808A

    CAS:
    GSK2837808A is a potent and selective inhibitor of lactate dehydrogenase A (LDHA) (IC50s: 1.9 and 14 nM for LDHA and LDHB, respectively).
    Formula:C31H25F2N5O7S
    Purezza:99.78% - 99.78%
    Colore e forma:Solid
    Peso molecolare:649.62
  • RS 61443

    CAS:
    <p>RS 61443 (Mycophenolate mofetil) is an immunosuppressant, a non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH)</p>
    Formula:C23H31NO7
    Purezza:99.37% - 99.91%
    Colore e forma:Solid
    Peso molecolare:433.5
  • MF-438

    CAS:
    MF-438 is an effective and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor (EC50: 2.3 nM for rSCD1).
    Formula:C19H18F3N5OS
    Purezza:98.98% - 99.50%
    Colore e forma:Solid
    Peso molecolare:421.44
  • CVT-10216

    CAS:
    CVT-10216 inhibits ALDH2 (IC50: 29 nM) and ALDH-1 (IC50: 1.3 μM), reducing alcohol intake and anxiety in rats.
    Formula:C24H19NO7S
    Purezza:98.76%
    Colore e forma:Solid
    Peso molecolare:465.48
  • XEN723

    CAS:
    XEN723 is a potent thiazolylimidazolidinone Stearoyl-CoA Desaturase (SCD1) inhibitor(IC50s of 45 and 524 nM in mouse and HepG2 cell, respectively).
    Formula:C21H20FN5O2S
    Purezza:99.5%
    Colore e forma:Solid
    Peso molecolare:425.48
  • ML390

    CAS:
    <p>ML390 exerts its potent differentiation effect on multiple leukemia models.</p>
    Formula:C21H21F3N2O3
    Purezza:99.76%
    Colore e forma:Solid
    Peso molecolare:406.4
  • PTC299

    CAS:
    <p>PTC299 ((4-chlorophenyl) (1S)-6-chloro-1-(4-methoxyphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carboxylate) is an orally active inhibitor of VEGFA mRNA</p>
    Formula:C25H20Cl2N2O3
    Purezza:99.72%
    Colore e forma:Solid
    Peso molecolare:467.34
  • Mutant IDH1 inhibitor

    CAS:
    Mutant IDH1 inhibitor is an effective inhibitor of mutant IDH1 R132H (IC50: < 72 nM).
    Formula:C25H34N6O3
    Purezza:98.3%
    Colore e forma:Solid
    Peso molecolare:466.58
  • BAY-2402234

    CAS:
    BAY-2402234: a selective DHODH inhibitor targeting myeloid cancers with low-nanomolar potency.
    Formula:C21H18ClF5N4O4
    Purezza:98.9%
    Colore e forma:Solid
    Peso molecolare:520.84
  • Mycophenolic acid

    CAS:
    Mycophenolic acid (Mycophenolate) is an inosine monophosphate dehydrogenase(IMPDH) inhibitor with anti-proliferative activity.
    Formula:C17H20O6
    Purezza:98.79% - 99.77%
    Colore e forma:Solid
    Peso molecolare:320.34
  • IDH-305

    CAS:
    <p>IDH-305: Oral, mutation-specific IDH1 inhibitor, 200x selective for R132 mutants; IC50: 27/28/6.14 nM for R132H/C/WT.</p>
    Formula:C23H22F4N6O2
    Purezza:99.68%
    Colore e forma:Solid
    Peso molecolare:490.45
  • Adrenosterone

    CAS:
    Adrenosterone (11-ketoandrostenedione) is a steroid hormone isolated from the adrenal cortex.
    Formula:C19H24O3
    Purezza:98.13% - 98.29%
    Colore e forma:Solid
    Peso molecolare:300.39
  • CBR-5884

    CAS:
    CBR-5884: active PHGDH inhibitor, IC50=33μM, disrupts serine synthesis, selectively targets high-serine cancers.
    Formula:C14H12N2O4S2
    Purezza:99.97%
    Colore e forma:Solid
    Peso molecolare:336.39
  • Trilostane

    CAS:
    Trilostane (Win 24540) is a synthetic derivative of androstane with adrenocortical suppressive properties.
    Formula:C20H27NO3
    Purezza:99.46% - >99.99%
    Colore e forma:Tan Crystals
    Peso molecolare:329.43
  • NCT-502

    CAS:
    NCT-502 (N-(4,6-dimethylpyridin-2-yl)-4-[5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carbothioamide) is a human phosphoglycerate dehydrogenase inhibitor,
    Formula:C18H20F3N5S
    Purezza:99.60%
    Colore e forma:Solid
    Peso molecolare:395.45
  • LY 345899

    CAS:
    <p>LY 345899 is a Folate analog and is a methylenetetrahydrofolate dehydrogenase and MTHFD2 inhibitor (IC50: 96 nM and 663 nM, respectively and a Ki: 18 nM for</p>
    Formula:C20H21N7O7
    Purezza:99.7%
    Colore e forma:Solid
    Peso molecolare:471.42
  • 4-Diethylaminobenzaldehyde

    CAS:
    <p>4-Diethylaminobenzaldehyde: reversible ALDH1 inhibitor (Ki: 4 nM), potent anti-androgen (IC50: 1.71μM).</p>
    Formula:C11H15NO
    Purezza:99.6%
    Colore e forma:Brown-Black Crystals
    Peso molecolare:177.24
  • DHODH-IN-11

    CAS:
    DHODH-IN-11 is a leflunomide derivative and weak dihydroorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.03.
    Formula:C15H11N3O2
    Purezza:98.14%
    Colore e forma:Solid
    Peso molecolare:265.27
  • Olutasidenib

    CAS:
    Olutasidenib (FT-2102), an IDH1 inhibitor (IC50: 21.2/114 nM), is studied for treating AML/MDS and can cross the blood-brain barrier.
    Formula:C18H15ClN4O2
    Purezza:98.57%
    Colore e forma:Solid
    Peso molecolare:354.79
  • LDH-IN-1

    CAS:
    LDH-IN-1 is a pyrazole-based human lactate dehydrogenase (LDH) inhibitor(IC50s of 32 and 27 nM for LDHA and LDHB, respectively).
    Formula:C30H26N4O4S2
    Purezza:99.6%
    Colore e forma:Solid
    Peso molecolare:570.68
  • CM121

    CAS:
    CM121, a reversible ALDH1A2 inhibitor, targets active site with IC50=0.54μM, Kd=1.1μM, using hydrophobic interactions.
    Formula:C24H17FN4O3S
    Colore e forma:Solid
    Peso molecolare:460.48
  • LDHA-IN-3

    CAS:
    LDHA-IN-3 is a potent selenobenzene-based LDHA inhibitor with a 145.2 nM IC50, useful in cancer research.
    Formula:C13H9F3Se
    Purezza:99.71%
    Colore e forma:Solid
    Peso molecolare:301.17
  • Octanoyl Coenzyme A (sodium salt)


    Octanoyl Coenzyme A (sodium salt) inhibits citrate synthase and glutamate dehydrogenase with an IC50 of 0.4–1.6 mM.
    Formula:C29H49N7NaO17P3S
    Colore e forma:Solid
    Peso molecolare:915.71
  • SCD1 inhibitor-3

    CAS:
    SCD1 inhibitor-3 (ML-270) is a highly effective and orally available compound that inhibits SCD1 with remarkable safety.
    Formula:C19H16FN7O2
    Purezza:99.5%
    Colore e forma:Solid
    Peso molecolare:393.37
  • Crelosidenib

    CAS:
    Crelosidenib is a potent and selective mutant IDH inhibitor for IDH1 R132H, IDH1 R132C, IDH2 R140Q, and IDH2 R172K mutases.
    Formula:C28H36N6O3
    Purezza:98.54%
    Colore e forma:Solid
    Peso molecolare:504.62
  • WAY-311610

    CAS:
    WAY-311610 is an HSD11B1 inhibitor targeting 11β-HSD1 enzyme with 0.34 μM IC; used for neuropathic and inflammatory pain research.
    Formula:C16H13F3N4O2
    Purezza:99.75%
    Colore e forma:Solid
    Peso molecolare:350.3
  • hDHODH-IN-13

    CAS:
    <p>hDHODH-IN-13 (compound w2), an inhibitor of human dihydroorotate dehydrogenase (hDHODH), exhibits an IC50 of 173.4 nM and has potential research applications in</p>
    Colore e forma:Soild
  • BVT-2733 hydrochloride

    CAS:
    BVT-2733 hydrochloride is a potent, selective, and orally active non-steroidal 11β-HSD1 inhibitor. It exhibits stronger inhibition on mouse 11β-HSD1 enzyme (IC50=96 nM) compared to the human 11β-HSD1 enzyme (IC50=3341 nM). BVT-2733 hydrochloride shows potential for research in arthritis and obesity-related diseases.
    Formula:C17H22Cl2N4O3S2
    Colore e forma:Solid
    Peso molecolare:465.42
  • WQQ-345


    WQQ-345, a BCAT1 inhibitor, exhibits an IC50 of 10.8 mM. In 67R cells, it reduces α-KG levels and upregulates H3K27me3 expression while downregulating the expression of glycolytic enzymes (PFKP and LDHA), leading to impaired glycolytic activity. Additionally, WQQ-345 demonstrates tumor-suppressive activity in a 67R subcutaneous xenograft model.
    Formula:C10H17NO2
    Colore e forma:Solid
    Peso molecolare:183.25
  • hDHODH-IN-8

    CAS:
    hDHODH-IN-8: potent hDHODH inhibitor, IC50 = 16 nM, antiproliferative, soluble, may research lymphoma.
    Formula:C21H15F6N3O4
    Purezza:98%
    Colore e forma:Soild
    Peso molecolare:487.35
  • IGUANA-1 free base

    CAS:
    IGUANA-1: selective ALDH1 B1 inhibitor, IC50=30 nM, hinders SW480 cell growth with IC50=2.46/0.39 μM in adherent/spheroid forms, for cancer research.
    Formula:C26H24ClN3O2
    Colore e forma:Solid
    Peso molecolare:445.94
  • 11β-HSD1-IN-11

    CAS:
    11β-HSd1-in-11 is a potent and competitive inhibitor of 11-β-hydroxysteroid dehydrogenase 1 (11β-HSD1) IN rats and humans with IC50 values of 0.34 μM and 0.13
    Formula:C15H11F3O3S
    Purezza:99.61%
    Colore e forma:Soild
    Peso molecolare:328.31
  • DSM705

    CAS:
    DSM705: Pyrrole-based, potent nanomolar Plasmodium DHODH inhibitor with strong antimalarial efficacy; spares mammalian DHODH.
    Formula:C19H19F3N6O
    Colore e forma:Solid
    Peso molecolare:404.397
  • MTHFD2-IN-2


    MTHFD2-IN-2 (compound 13) serves as a potent inhibitor of methylenetetrahydrofolate dehydrogenase (MTHFD2) [1].
    Formula:C22H18N4O5
    Colore e forma:Solid
    Peso molecolare:418.4
  • 17β-HSD10-IN-1

    CAS:
    17β-HSD10-IN-1 is a 17β-hydroxysteroid dehydrogenase type 10 inhibitor with blood-brain permeability and potency for the study of Alzheimer's disease.
    Formula:C16H13ClN4O3S
    Purezza:98.47%
    Colore e forma:Soild
    Peso molecolare:376.82
  • PDK-IN-2


    PDK-IN-2 (Compound 1F), with an IC50 of 68 nM, is a potent PDK inhibitor that downregulates the expression of PDK1 and PDK4 in cells.
    Formula:C17H23AsCl2N2O2S2
    Colore e forma:Solid
    Peso molecolare:497.33
  • TC HSD 21

    CAS:
    <p>TC HSD 21 is a potent and highly selective inhibitor of 17β-hydroxysteroid dehydrogenase type 3 (IC50 = 14 nM).</p>
    Formula:C17H12BrNO3S2
    Purezza:98.5%
    Colore e forma:Solid
    Peso molecolare:422.32
  • 2,3-Dihydroxybenzaldehyde

    CAS:
    2,3-Dihydroxybenzaldehyde exhibits activity against NADH dehydrogenase (Km = 35 µM) and can be used in biochemical experiments and drug synthesis.
    Formula:C7H6O3
    Colore e forma:Solid
    Peso molecolare:138.12
  • MTHFD2-IN-3


    MTHFD2-IN-3 (compound 10), a potent inhibitor of methylenetetrahydrofolate dehydrogenase (MTHFD2), demonstrates significant efficacy in obstructing the activity
    Formula:C22H19NO7S
    Colore e forma:Solid
    Peso molecolare:441.45
  • MCI-INI-3

    CAS:
    <p>MCI-INI-3 is a selective competitive inhibitor of human ALDH1A3, with a Ki value of 0.55 μM for ALDH1A3 and 78.2 μM for ALDH1A1. It inhibits retinoic acid biosynthesis and can reduce the viability of glioblastoma cells GSC-83 and GSC-326.</p>
    Formula:C21H15N3O4
    Colore e forma:Solid
    Peso molecolare:373.36
  • SW209049

    CAS:
    SW209049 is a stearoyl-CoA 9-desaturase inhibitor. SW209049 exhivits potent activity against H2122 cell with IC50 of 0.13uM.
    Formula:C25H18N2O4S
    Purezza:99.72%
    Colore e forma:Solid
    Peso molecolare:442.49
  • Nedosiran sodium

    CAS:
    <p>Nedosiran sodium, a GalNAc-dsRNA conjugate, is engineered to suppress the synthesis of the hepatic lactate dehydrogenase (LDH) enzyme.</p>
    Colore e forma:Solid
  • (Rac)-BMS-816336


    <p>(Rac)-BMS-816336 is a racemic 11β-HSD1 inhibitor; IC50: 10 nM (human), 68 nM (mouse), metabolically stable.</p>
    Formula:C21H27NO3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:341.44
  • Ascochlorin A

    CAS:
    Ascochlorin A, a compound with a dissociation constant (K D) of 3.29 μM, serves as a novel and potent human dihydroorotate dehydrogenase (hDHODH) inhibitor
    Formula:C23H31ClO4
    Colore e forma:Solid
    Peso molecolare:406.95
  • hDHODH-IN-12


    hDHODH-IN-12 is a potent inhibitor of dihydroorotate dehydrogenase (DHODH), exhibiting an inhibitory concentration (IC50) of 0.421 μM.
    Formula:C22H15F3N4O3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:440.37
  • KOTX1

    CAS:
    KOTX1 is an orally active and selective inhibitor of ALDH1A3. In a diabetic mouse model, KOTX1 improves glucose tolerance, insulin secretion, and blood glucose levels.
    Formula:C17H16FN3O2
    Colore e forma:Solid
    Peso molecolare:313.33
  • hDHODH-IN-16


    <p>hDHODH-IN-16 (Compound 3t) is an inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an IC50 of 0.11 μM. It demonstrates very low cytotoxicity towards healthy HaCaT cells, with an IC50 value exceeding 200 μM.</p>
    Formula:C18H20N2O2
    Colore e forma:Solid
    Peso molecolare:296.36
  • BMS-337197

    CAS:
    BMS-337197 is an IMPDH inhibitor.
    Formula:C26H27N5O5
    Colore e forma:Soild
    Peso molecolare:489.52
  • Antiproliferative agent-13

    CAS:
    <p>Antiproliferative agent-13 is a compound with antiproliferative activity.</p>
    Formula:C20H18N2O6
    Purezza:99.723%
    Colore e forma:Solid
    Peso molecolare:382.37
  • 18β-Glycyrrhetyl-3-O-sulfate

    CAS:
    18β-Glycyrrhetyl-3-O-sulfate (Glycyrrhetic acid 3-O-(hydrogen sulfate)), a major metabolite of Glycyrrhetinic acid (GA), serves as a potent inhibitor of type 2
    Formula:C30H46O7S
    Colore e forma:Solid
    Peso molecolare:550.75
  • Osmanthuside H

    CAS:
    Osmanthuside H is a useful organic compound for research related to life sciences. The catalog number is T125796 and the CAS number is 149155-70-4.
    Formula:C19H28O11
    Colore e forma:Solid
    Peso molecolare:432.422
  • DHODH-IN-16

    CAS:
    DHODH-IN-16 is an effective inhibitor of dihydroorotate dehydrogenase (DHODH, IC50 = 0.396 nM for human).
    Formula:C24H25FN4O3
    Purezza:99.64%
    Colore e forma:Solid
    Peso molecolare:436.48
  • BMS-770767

    CAS:
    <p>BMS-770767 is a novel 11-betahydroxysteroid dehydrogenase type I (11ß-HSD1) inhibitor.</p>
    Formula:C19H18ClN3O2
    Colore e forma:Solid
    Peso molecolare:355.82
  • Diethanolamine hydrochloride

    CAS:
    Diethanolamine hydrochloride is HSD17B4 (hydroxysteroid 17-beta dehydrogenase 4) and pregnane X receptor (PXR), p53 Estrogen receptor.
    Formula:C4H12ClNO2
    Purezza:99.69%
    Colore e forma:Solid
    Peso molecolare:141.6
  • 11β-HSD1 inibitor 19

    CAS:
    3-chloro-4-sulfonyl-Benzonitrile inhibits hHSD1/mHSD1, IC50: 16nM/10nM.
    Formula:C19H16ClF4N3O2S
    Purezza:99.58%
    Colore e forma:Soild
    Peso molecolare:461.86
  • 11β-HSD1 inibitor 17

    CAS:
    11β-HSD1 inibitor 17 is an inhibitor of 11β-hydroxysteroid dehydrogenase (11β-HSD1).
    Formula:C22H20F3N3O2S
    Purezza:99.26% - 99.72%
    Colore e forma:Soild
    Peso molecolare:447.47
  • PTOTAC HSD17B13 degrader 1

    CAS:
    PTOTAC HSD17B13 Degrader 1, a PROTAC designed to target 17β-HSD 13 (HSD17B13), incorporates several key components. These include the PROTAC target protein ligand HSD17B13 Degrader 2, the PROTAC Linker tert-Butyl 5-bromoisoindoline-2-carboxylate, and the E3 ubiquitin ligase ligand E3 Ligase Ligand 31. Notably, the conjugate formed by the E3 ubiquitin ligase ligand and the linker is recognized as E3 Ligase Ligand-linker Conjugate 114.
    Formula:C45H45ClF3N7O5
    Colore e forma:Solid
    Peso molecolare:856.33
  • SKI2852

    CAS:
    SKI2852 is an 11β-HSD1 inhibitor that improves metabolic syndrome in diabetic mouse models.
    Formula:C27H34FN5O4S
    Purezza:99.89%
    Colore e forma:Solid
    Peso molecolare:543.65
  • DHODH-IN-18

    CAS:
    DHODH-IN-18 is a human DHODH inhibitor ( IC 50 = 0.2 nM).
    Formula:C21H16ClF5N6O4
    Colore e forma:Solid
    Peso molecolare:546.84
  • MTHFD2-IN-4 sodium


    MTHFD2-IN-4 sodium, a potent inhibitor of MTHFD2 and a tricyclic coumarin derivative, is applicable in cancer research [1].
    Formula:C26H21F6N2NaO5
    Colore e forma:Solid
    Peso molecolare:578.44
  • D34-919

    CAS:
    D34-919 is a potent inhibitor of the ALDH1A3-PKM2 interaction, effectively inhibiting the ALDH1A3-mediated tetramerization enhancement of PKM2. Treatment mediated by D34-919 both in vitro and in vivo enhances and restores apoptosis and sensitivity in glioblastoma (GBM) cells induced by radiochemotherapy.
    Formula:C22H27N5OS
    Peso molecolare:409.55
  • LDHA-IN-8

    CAS:
    LDHA-IN-8, an inhibitor, inhibits the proliferation of pancreatic and lung cancer cells, decreasing the intracellular lactate content and increasing ROS levels.
    Formula:C15H14N4O2
    Purezza:99.73%
    Colore e forma:Solid
    Peso molecolare:282.3
  • MTHFD2-IN-1


    <p>MTHFD2-IN-1 (compound 12) is a potent inhibitor of methylenetetrahydrofolate dehydrogenase (MTHFD2) [1].</p>
    Formula:C24H21NO6
    Colore e forma:Solid
    Peso molecolare:419.43
  • MTHFD2-IN-4


    MTHFD2-IN-4, a tricyclic coumarin derivative, serves as a potent inhibitor of MTHFD2 and has applications in cancer research [1].
    Formula:C26H21F6N2O5
    Colore e forma:Solid
    Peso molecolare:555.45
  • D-Lactate dehydrogenase

    CAS:
    <p>D-LDH is an oxidoreductase turning D-lactate into pyruvate, using NAD+/NADP+; prevalent in bacteria and fungi, key for biochemical research.</p>
    Colore e forma:Solid
  • DHODH-IN-23

    CAS:
    <p>DHODH-IN-23 is a DHODH inhibitor with oral activity. DHODH-IN-23 is often used in cancer research.</p>
    Formula:C24H21ClFNO4
    Purezza:99.7%
    Colore e forma:Solid
    Peso molecolare:441.88
  • IGUANA-1

    CAS:
    <p>IGUANA-1 is a highly efficient and selective ALDH1B1 inhibitor that inhibits the growth of colorectal cancer cells and colorectal cancer cell-derived organoids.</p>
    Formula:C27H26ClN3O4
    Purezza:99.08%
    Colore e forma:Solid
    Peso molecolare:491.97
  • HSD17B13-IN-71

    CAS:
    HSD17B13-IN-71 (Compound 149), an effective inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), displays potent activity with an IC 50 value of ≤ 0.1 μM against estradiol. This compound is applicable in the study of various disorders including liver diseases, metabolic diseases, and cardiovascular conditions such as NAFLD or NASH, in addition to drug-induced liver injury (DILI) [1].
    Formula:C25H16Cl2F5N3O4
    Peso molecolare:588.31
  • DSM1465


    <p>DSM1465 (Compound 82) is a potent and selective inhibitor of P. falciparum dihydroorotate dehydrogenase (PfDHODH) with an IC50 value of 15 nM. It inhibits P. falciparum 3D7 (Pf3D7) parasites with an EC50 value of 1.4 nM and demonstrates significant in vivo efficacy in humanized P. falciparum mouse models.</p>
    Formula:C17H12ClF6N5O2
    Colore e forma:Solid
    Peso molecolare:467.753
  • PDK-IN-1

    CAS:
    PDK-IN-1, a PDK inhibitor, IC50: 0.03μM (PDK1), 0.1μM (HSP90), reduces tumor mass.
    Formula:C20H16BrN7O
    Colore e forma:Solid
    Peso molecolare:450.29
  • Necroptosis-IN-3

    CAS:
    <p>Necroptosis-IN-3 (Cyclohexanecarboxamide, N-(2-thienylmethyl)-) (Compound 69) is a Necroptosis inhibitor that inhibits TNF-α induced necroptosis.</p>
    Formula:C12H17NOS
    Purezza:99.85%
    Colore e forma:Soild
    Peso molecolare:223.33
  • hDHODH-IN-17


    hDHODH-IN-17 (Compound 10) is an inhibitor of human dihydroorotate dehydrogenase (hDHODH), with an IC50 value of 0.188 μM. It fits well with the hDHODH active site and interacts effectively with amino acid residues. hDHODH-IN-17 is a potential broad-spectrum antiviral drug.
  • Glucose dehydrogenase

    CAS:
    Glucose dehydrogenase (GDH) is a redox enzyme typically occurring as dimeric or tetrameric proteins. GDH utilises external NAD or NADP to oxidise glucose .
  • ALDH1A2-IN-1

    CAS:
    ALDH1A2-IN-1 is a reversible active-site-directed ALDH1A2 inhibitor preventing spermatogenesis, useful in male contraceptive research.
    Formula:C21H26N4O4S
    Purezza:99.51%
    Colore e forma:Solid
    Peso molecolare:430.52
  • BMS-566419

    CAS:
    BMS-566419: Acridinone-based IMPDH inhibitor for studying graft rejection.
    Formula:C28H30FN5O2
    Colore e forma:Solid
    Peso molecolare:487.57
  • DSM502

    CAS:
    DSM502 DSM502 is a dihydroorotic acid dehydrogenase (DHODH) inhibitor with antimalarial activity that inhibits Plasmodium DHODH and can be used as a lead for antimalarial compounds.
    Formula:C16H16F3N3O
    Purezza:99.52%
    Colore e forma:Solid
    Peso molecolare:323.31
  • Aldehyde dehydrogenase (NAD(P))

    CAS:
    <p>ALDH catalyzes oxidation of aldehydes to acids, reducing NAD(P) to NAD(P)H, helping alleviate aldehyde stress.</p>
    Colore e forma:Solid
  • DSM265

    CAS:
    DSM265 (PfSPZ) is a dihydroorotic acid dehydrogenase inhibitor with antimalarial activity.DSM265 can be used for the treatment of malaria infections.
    Formula:C14H12F7N5S
    Purezza:99.79%
    Colore e forma:Solid
    Peso molecolare:415.33
  • 2-Bromoacetamide

    CAS:
    <p>2-Bromoacetamide (α-Bromoacetamide) is a class of disinfection by-products that exhibit developmental toxicity in animals.</p>
    Formula:C2H4BrNO
    Purezza:99.83%
    Colore e forma:Solid
    Peso molecolare:137.96
  • Ketogestin

    CAS:
    Ketogestin is a progestational steroid and an inhibitor of enzyme 11β-hydroxysteroid dehydrogenase, and a weak negative modulator of GABAA receptors.
    Formula:C21H28O3
    Purezza:99.19%
    Colore e forma:Solid
    Peso molecolare:328.45
  • PKUMDL-WQ-2201

    CAS:
    PKUMDL-WQ-2201 is a selective allosteric inhibitor of phosphoglycerate dehydrogenase (PHGDH) with Anti-tumor Activity, it binds to site II.
    Formula:C15H14ClN3O3S
    Colore e forma:Solid
    Peso molecolare:351.81
  • ALDH1A3-IN-1

    CAS:
    ALDH1A3-IN-1 (Compound 14) is a potent inhibitor of ALDH1A3 which can be used in prostate cancer research (IC50 = 0.63 μM; Ki = 0.46 μM) [1].
    Formula:C13H18BrNO
    Colore e forma:Solid
    Peso molecolare:284.19
  • PS10

    CAS:
    PS10 is a broad-spectrum PDK inhibitor that inhibits PDK2 and significantly increases the activity of the pyruvate dehydrogenase complex.
    Formula:C14H13NO6S
    Purezza:99.01%
    Colore e forma:Solid
    Peso molecolare:323.32
  • ALDH3A1-IN-1

    CAS:
    ALDH3A1-IN-1 (Compound 18) is a potent inhibitor of ALDH3A1 with IC50 of 1.61 μM, outperforms DEAB in prostate cancer cells.
    Formula:C13H18N2O3
    Purezza:99.86%
    Colore e forma:Solid
    Peso molecolare:250.29
  • 4-Isopropoxybenzaldehyde

    CAS:
    ALDH1A3-IN-3 inhibits ALDH1A3 (IC50: 0.26 μM), acts on ALDH3A1, and is used in prostate cancer research.
    Formula:C10H12O2
    Purezza:99.00%
    Colore e forma:Solid
    Peso molecolare:164.2
  • ABT-384

    CAS:
    ABT-384 is a high-affinity, selective 11β-HSD1 inhibitor capable of suppressing hepatic and central nervous system HSD-1 activity for depressive disorder.
    Formula:C25H34F3N5O2
    Purezza:99.863%
    Colore e forma:Solid
    Peso molecolare:493.58
  • Brequinar

    CAS:
    Brequinar (NSC-368390) is a potent inhibitor of dihydroorotate dehydrogenase, with potent activities against a broad spectrum of viruses.
    Formula:C23H15F2NO2
    Purezza:99.1% - 99.57%
    Colore e forma:Solid
    Peso molecolare:375.37
  • BVT 2733

    CAS:
    <p>BVT 2733 is a new, non-steroidal, isoform-specific inhibitor of 11β-HSD1.</p>
    Formula:C17H21ClN4O3S2
    Purezza:98% - 99.64%
    Colore e forma:Solid
    Peso molecolare:428.96
  • AGI-6780

    CAS:
    AGI-6780 is a potent and selective inhibitor of IDH2 R140Q mutant.
    Formula:C21H18F3N3O3S2
    Purezza:98.19% - 99.7%
    Colore e forma:Solid
    Peso molecolare:481.51
  • (E/Z)-Teriflunomide

    CAS:
    (E/Z)-Teriflunomide (Aubagio), a orally-available Pyrimidine Synthesis Inhibitor, is used to treat relapsing multiple sclerosis.
    Formula:C12H9F3N2O2
    Purezza:99.49% - 99.76%
    Colore e forma:White Solid
    Peso molecolare:270.21
  • Nitrofurazone

    CAS:
    Nitrofurazone (Furacilin) is a topical anti-infective agent effective against gram-negative and gram-positive bacteria.
    Formula:C6H6N4O4
    Purezza:99.87%
    Colore e forma:Pale Yellow Needles Solution) 6 0 - 6 5 Alkaline Solutions Are Dark Orange (Ntp 1992)
    Peso molecolare:198.14
  • VER-246608

    CAS:
    <p>VER-246608 inhibits PDK (IC50: 35-91 nM), boosts PDC, reduces glycolysis, causes cancer cell cytostasis, and enhances doxorubicin effects.</p>
    Formula:C28H23ClF2N4O4
    Purezza:98.5%
    Colore e forma:Solid
    Peso molecolare:552.96
  • Galloflavin

    CAS:
    Galloflavin is a lactate dehydrogenase inhibitor. Galloflavin inhibits both human LDH isoforms (type A and type B).Cost-effective and quality-assured.
    Formula:C12H6O8
    Purezza:96.24% - 97.47%
    Colore e forma:Solid
    Peso molecolare:278.17
  • NCT-505

    CAS:
    NCT-505 is a potent and selective inhibitor of aldehyde dehydrogenase (ALDH1A1, IC50 = 7 nM) and a weak inhibitor of hALDH1A2, hALDH1A3, hALDH2, hALDH3A1 with
    Formula:C27H28FN5O3S
    Purezza:99.93%
    Colore e forma:Solid
    Peso molecolare:521.61
  • R162

    CAS:
    R162 is an effective glutamate dehydrogenase 1 (GDH1) inhibitor.
    Formula:C17H12O3
    Purezza:96.21% - 98.15%
    Colore e forma:Solid
    Peso molecolare:264.28
  • PfDHODH-IN-2

    CAS:
    <p>PfDHODH-IN-2: powerful antimalarial, blocks PfDHODH (IC50: 1.11 μM), for malaria research.</p>
    Formula:C13H12ClNO3S
    Purezza:98.9%
    Colore e forma:Solid
    Peso molecolare:297.76
  • BI-187004

    CAS:
    BI-187004 is an 11β-hydroxysteroid dehydrogenase 1 inhibitor.
    Formula:C21H18N4O
    Purezza:98.63%
    Colore e forma:Solid
    Peso molecolare:342.39