Deidrogenasi
Le deidrogenasi sono enzimi coinvolti nelle reazioni di ossidoriduzione delle vie metaboliche, svolgendo un ruolo centrale nella produzione di energia e nella respirazione cellulare. Questi enzimi sono cruciali per processi come il ciclo dell'acido citrico, la glicolisi e l'ossidazione degli acidi grassi. Gli inibitori delle deidrogenasi sono strumenti importanti nello studio delle malattie metaboliche, del cancro e dello stress ossidativo. Presso CymitQuimica, offriamo una selezione completa di inibitori delle deidrogenasi per supportare la tua ricerca in metabolismo, biologia del cancro e biochimica.
Trovati 302 prodotti di "Deidrogenasi"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
KPLH1130
CAS:<p>KPLH1130, a PDK inhibitor, boosts glucose tolerance and reduces inflammation in high-fat diet mice.</p>Formula:C15H13N3O3Purezza:99.07%Colore e forma:SolidPeso molecolare:283.28NCT-502
CAS:NCT-502 (N-(4,6-dimethylpyridin-2-yl)-4-[5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carbothioamide) is a human phosphoglycerate dehydrogenase inhibitor,Formula:C18H20F3N5SPurezza:99.60%Colore e forma:SolidPeso molecolare:395.45Ref: TM-T16277
2mg39,00€5mg57,00€10mg87,00€25mg159,00€50mg240,00€100mg415,00€500mg933,00€1mL*10mM (DMSO)63,00€DHODH-IN-11
CAS:DHODH-IN-11 is a leflunomide derivative and weak dihydroorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.03.Formula:C15H11N3O2Purezza:98.14%Colore e forma:SolidPeso molecolare:265.27XEN723
CAS:XEN723 is a potent thiazolylimidazolidinone Stearoyl-CoA Desaturase (SCD1) inhibitor(IC50s of 45 and 524 nM in mouse and HepG2 cell, respectively).Formula:C21H20FN5O2SPurezza:99.5%Colore e forma:SolidPeso molecolare:425.48Ref: TM-T13356
1mg55,00€5mg116,00€10mg178,00€25mg304,00€50mg437,00€100mg615,00€200mg830,00€1mL*10mM (DMSO)139,00€BAY-2402234
CAS:BAY-2402234: a selective DHODH inhibitor targeting myeloid cancers with low-nanomolar potency.Formula:C21H18ClF5N4O4Purezza:98.9%Colore e forma:SolidPeso molecolare:520.84Ref: TM-T14501
1mg173,00€2mg246,00€5mg368,00€10mg567,00€25mg905,00€50mg1.225,00€100mg1.644,00€1mL*10mM (DMSO)424,00€RS 61443
CAS:RS 61443 (Mycophenolate mofetil) is an immunosuppressant, a non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH)Formula:C23H31NO7Purezza:99.37% - 99.96%Colore e forma:SolidPeso molecolare:433.5GSK2837808A
CAS:GSK2837808A is a potent and selective inhibitor of lactate dehydrogenase A (LDHA) (IC50s: 1.9 and 14 nM for LDHA and LDHB, respectively).Formula:C31H25F2N5O7SPurezza:99.78% - 99.78%Colore e forma:SolidPeso molecolare:649.62Ref: TM-T15435
1mg48,00€5mg111,00€10mg170,00€25mg329,00€50mg455,00€100mg645,00€1mL*10mM (DMSO)159,00€PTC299
CAS:PTC299 ((4-chlorophenyl) (1S)-6-chloro-1-(4-methoxyphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carboxylate) is an orally active inhibitor of VEGFA mRNAFormula:C25H20Cl2N2O3Purezza:99.72%Colore e forma:SolidPeso molecolare:467.34Ref: TM-T12574
1mg117,00€5mg243,00€10mg369,00€25mg622,00€50mg885,00€100mg1.206,00€1mL*10mM (DMSO)250,00€Mycophenolic acid
CAS:Mycophenolic acid (Mycophenolate) is an inosine monophosphate dehydrogenase(IMPDH) inhibitor with anti-proliferative activity.Formula:C17H20O6Purezza:98.79% - 99.77%Colore e forma:SolidPeso molecolare:320.34LY 345899
CAS:<p>LY 345899 is a Folate analog and is a methylenetetrahydrofolate dehydrogenase and MTHFD2 inhibitor (IC50: 96 nM and 663 nM, respectively and a Ki: 18 nM for</p>Formula:C20H21N7O7Purezza:99.7%Colore e forma:SolidPeso molecolare:471.42Trilostane
CAS:Trilostane (Win 24540) is a synthetic derivative of androstane with adrenocortical suppressive properties.Formula:C20H27NO3Purezza:99.46% - >99.99%Colore e forma:Tan CrystalsPeso molecolare:329.43IDH-305
CAS:IDH-305: Oral, mutation-specific IDH1 inhibitor, 200x selective for R132 mutants; IC50: 27/28/6.14 nM for R132H/C/WT.Formula:C23H22F4N6O2Purezza:99.68%Colore e forma:SolidPeso molecolare:490.45Mutant IDH1 inhibitor
CAS:Mutant IDH1 inhibitor is an effective inhibitor of mutant IDH1 R132H (IC50: < 72 nM).Formula:C25H34N6O3Purezza:98.3%Colore e forma:SolidPeso molecolare:466.58Ref: TM-T16161
1mg42,00€5mg90,00€10mg135,00€25mg221,00€50mg324,00€100mg452,00€200mg630,00€1mL*10mM (DMSO)94,00€CBR-5884
CAS:CBR-5884: active PHGDH inhibitor, IC50=33μM, disrupts serine synthesis, selectively targets high-serine cancers.Formula:C14H12N2O4S2Purezza:99.97%Colore e forma:SolidPeso molecolare:336.39Adrenosterone
CAS:Adrenosterone (11-ketoandrostenedione) is a steroid hormone isolated from the adrenal cortex.Formula:C19H24O3Purezza:98.13% - 98.29%Colore e forma:SolidPeso molecolare:300.39SCD1 inhibitor-4
CAS:<p>SCD1 inhibitor-4 is stearoylCoA desaturase-1 (SCD1) inhibitor. SCD1 inhibitor-4 can be used for the research of diabetes.</p>Formula:C17H16F3N5OPurezza:99.71%Colore e forma:SolidPeso molecolare:363.34LDH-IN-1
CAS:LDH-IN-1 is a pyrazole-based human lactate dehydrogenase (LDH) inhibitor(IC50s of 32 and 27 nM for LDHA and LDHB, respectively).Formula:C30H26N4O4S2Purezza:99.6%Colore e forma:SolidPeso molecolare:570.68Ref: TM-T11829
1mg188,00€5mg393,00€10mg588,00€25mg938,00€50mg1.359,00€100mg1.786,00€200mg2.442,00€1mL*10mM (DMSO)494,00€CAY10566
CAS:CAY10566 is a potent SCD1 inhibitor, orally bioavailable, with IC50s: HepG2 cells, 7.9nM; mouse, 4.5nM; human, 26nM.Formula:C18H17ClFN5O2Purezza:99.5% - 99.54%Colore e forma:SolidPeso molecolare:389.81Ref: TM-T14878
1mg50,00€5mg138,00€10mg205,00€25mg373,00€50mg533,00€100mg748,00€200mg1.008,00€1mL*10mM (DMSO)118,00€ML390
CAS:<p>ML390 exerts its potent differentiation effect on multiple leukemia models.</p>Formula:C21H21F3N2O3Purezza:99.76%Colore e forma:SolidPeso molecolare:406.44-Diethylaminobenzaldehyde
CAS:<p>4-Diethylaminobenzaldehyde: reversible ALDH1 inhibitor (Ki: 4 nM), potent anti-androgen (IC50: 1.71μM).</p>Formula:C11H15NOPurezza:99.6%Colore e forma:Brown-Black CrystalsPeso molecolare:177.24Olutasidenib
CAS:Olutasidenib (FT-2102), an IDH1 inhibitor (IC50: 21.2/114 nM), is studied for treating AML/MDS and can cross the blood-brain barrier.Formula:C18H15ClN4O2Purezza:98.57%Colore e forma:SolidPeso molecolare:354.79Ref: TM-T16384
1mg62,00€5mg169,00€10mg264,00€25mg487,00€50mg710,00€100mg998,00€200mg1.320,00€1mL*10mM (DMSO)178,00€CVT-10216
CAS:CVT-10216 inhibits ALDH2 (IC50: 29 nM) and ALDH-1 (IC50: 1.3 μM), reducing alcohol intake and anxiety in rats.Formula:C24H19NO7SPurezza:98.76%Colore e forma:SolidPeso molecolare:465.48MF-438
CAS:MF-438 is an effective and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor (EC50: 2.3 nM for rSCD1).Formula:C19H18F3N5OSPurezza:98.98% - 99.50%Colore e forma:SolidPeso molecolare:421.44Ref: TM-T16068
1mg97,00€2mg144,00€5mg215,00€10mg328,00€25mg557,00€50mg797,00€100mg1.103,00€500mg2.205,00€1mL*10mM (DMSO)235,00€WAY-311610
CAS:WAY-311610 is an HSD11B1 inhibitor targeting 11β-HSD1 enzyme with 0.34 μM IC; used for neuropathic and inflammatory pain research.Formula:C16H13F3N4O2Purezza:99.75%Colore e forma:SolidPeso molecolare:350.3LDHA-IN-3
CAS:LDHA-IN-3 is a potent selenobenzene-based LDHA inhibitor with a 145.2 nM IC50, useful in cancer research.Formula:C13H9F3SePurezza:99.71%Colore e forma:SolidPeso molecolare:301.17Ref: TM-T39805
1mg55,00€5mg119,00€10mg187,00€25mg393,00€50mg547,00€100mg747,00€200mg1.026,00€1mL*10mM (DMSO)131,00€Ascochlorin A
CAS:Ascochlorin A, a compound with a dissociation constant (K D) of 3.29 μM, serves as a novel and potent human dihydroorotate dehydrogenase (hDHODH) inhibitorFormula:C23H31ClO4Colore e forma:SolidPeso molecolare:406.95CM121
CAS:CM121, a reversible ALDH1A2 inhibitor, targets active site with IC50=0.54μM, Kd=1.1μM, using hydrophobic interactions.Formula:C24H17FN4O3SColore e forma:SolidPeso molecolare:460.48hDHODH-IN-12
hDHODH-IN-12 is a potent inhibitor of dihydroorotate dehydrogenase (DHODH), exhibiting an inhibitory concentration (IC50) of 0.421 μM.Formula:C22H15F3N4O3Purezza:98%Colore e forma:SolidPeso molecolare:440.37SCD1 inhibitor-3
CAS:SCD1 inhibitor-3 (ML-270) is a highly effective and orally available compound that inhibits SCD1 with remarkable safety.Formula:C19H16FN7O2Purezza:99.5%Colore e forma:SolidPeso molecolare:393.37Ref: TM-T38683
1mg92,00€5mg187,00€10mg298,00€25mg507,00€50mg730,00€100mg1.026,00€1mL*10mM (DMSO)205,00€hDHODH-IN-13
CAS:hDHODH-IN-13 (compound w2), an inhibitor of human dihydroorotate dehydrogenase (hDHODH), exhibits an IC50 of 173.4 nM and has potential research applications inColore e forma:Soild18β-Glycyrrhetyl-3-O-sulfate
CAS:18β-Glycyrrhetyl-3-O-sulfate (Glycyrrhetic acid 3-O-(hydrogen sulfate)), a major metabolite of Glycyrrhetinic acid (GA), serves as a potent inhibitor of type 2Formula:C30H46O7SColore e forma:SolidPeso molecolare:550.75WQQ-345
WQQ-345, a BCAT1 inhibitor, exhibits an IC50 of 10.8 mM. In 67R cells, it reduces α-KG levels and upregulates H3K27me3 expression while downregulating the expression of glycolytic enzymes (PFKP and LDHA), leading to impaired glycolytic activity. Additionally, WQQ-345 demonstrates tumor-suppressive activity in a 67R subcutaneous xenograft model.Formula:C10H17NO2Colore e forma:SolidPeso molecolare:183.25BVT-2733 hydrochloride
CAS:BVT-2733 hydrochloride is a potent, selective, and orally active non-steroidal 11β-HSD1 inhibitor. It exhibits stronger inhibition on mouse 11β-HSD1 enzyme (IC50=96 nM) compared to the human 11β-HSD1 enzyme (IC50=3341 nM). BVT-2733 hydrochloride shows potential for research in arthritis and obesity-related diseases.Formula:C17H22Cl2N4O3S2Colore e forma:SolidPeso molecolare:465.42BMS-337197
CAS:BMS-337197 is an IMPDH inhibitor.Formula:C26H27N5O5Colore e forma:SoildPeso molecolare:489.52IGUANA-1 free base
CAS:IGUANA-1: selective ALDH1 B1 inhibitor, IC50=30 nM, hinders SW480 cell growth with IC50=2.46/0.39 μM in adherent/spheroid forms, for cancer research.Formula:C26H24ClN3O2Colore e forma:SolidPeso molecolare:445.94hDHODH-IN-8
CAS:hDHODH-IN-8: potent hDHODH inhibitor, IC50 = 16 nM, antiproliferative, soluble, may research lymphoma.Formula:C21H15F6N3O4Purezza:98%Colore e forma:SoildPeso molecolare:487.35Osmanthuside H
CAS:Osmanthuside H is a useful organic compound for research related to life sciences. The catalog number is T125796 and the CAS number is 149155-70-4.Formula:C19H28O11Colore e forma:SolidPeso molecolare:432.422PDK-IN-2
PDK-IN-2 (Compound 1F), with an IC50 of 68 nM, is a potent PDK inhibitor that downregulates the expression of PDK1 and PDK4 in cells.Formula:C17H23AsCl2N2O2S2Colore e forma:SolidPeso molecolare:497.33TC HSD 21
CAS:TC HSD 21 is a potent and highly selective inhibitor of 17β-hydroxysteroid dehydrogenase type 3 (IC50 = 14 nM).Formula:C17H12BrNO3S2Purezza:99.32%Colore e forma:SolidPeso molecolare:422.32Ref: TM-T13100
1mg42,00€5mg90,00€10mg137,00€25mg239,00€50mg344,00€100mg462,00€200mg625,00€1mL*10mM (DMSO)90,00€2,3-Dihydroxybenzaldehyde
CAS:2,3-Dihydroxybenzaldehyde exhibits activity against NADH dehydrogenase (Km = 35 µM) and can be used in biochemical experiments and drug synthesis.Formula:C7H6O3Colore e forma:SolidPeso molecolare:138.12MTHFD2-IN-3
MTHFD2-IN-3 (compound 10), a potent inhibitor of methylenetetrahydrofolate dehydrogenase (MTHFD2), demonstrates significant efficacy in obstructing the activityFormula:C22H19NO7SColore e forma:SolidPeso molecolare:441.45MCI-INI-3
CAS:MCI-INI-3 is a selective competitive inhibitor of human ALDH1A3, with a Ki value of 0.55 μM for ALDH1A3 and 78.2 μM for ALDH1A1. It inhibits retinoic acid biosynthesis and can reduce the viability of glioblastoma cells GSC-83 and GSC-326.Formula:C21H15N3O4Colore e forma:SolidPeso molecolare:373.36DSM705
CAS:DSM705: Pyrrole-based, potent nanomolar Plasmodium DHODH inhibitor with strong antimalarial efficacy; spares mammalian DHODH.Formula:C19H19F3N6OColore e forma:SolidPeso molecolare:404.397SW209049
CAS:SW209049 is a stearoyl-CoA 9-desaturase inhibitor. SW209049 exhivits potent activity against H2122 cell with IC50 of 0.13uM.Formula:C25H18N2O4SPurezza:99.72%Colore e forma:SolidPeso molecolare:442.49Ref: TM-T9859
1mg77,00€5mg158,00€10mg225,00€25mg338,00€50mg475,00€100mg638,00€200mg845,00€1mL*10mM (DMSO)170,00€17β-HSD10-IN-1
CAS:17β-HSD10-IN-1 is a 17β-hydroxysteroid dehydrogenase type 10 inhibitor with blood-brain permeability and potency for the study of Alzheimer's disease.Formula:C16H13ClN4O3SPurezza:98.47%Colore e forma:SoildPeso molecolare:376.82(Rac)-BMS-816336
(Rac)-BMS-816336 is a racemic 11β-HSD1 inhibitor; IC50: 10 nM (human), 68 nM (mouse), metabolically stable.Formula:C21H27NO3Purezza:98%Colore e forma:SolidPeso molecolare:341.44Nedosiran sodium
CAS:<p>Nedosiran sodium, a GalNAc-dsRNA conjugate, is engineered to suppress the synthesis of the hepatic lactate dehydrogenase (LDH) enzyme.</p>Colore e forma:SolidDiethanolamine hydrochloride
CAS:Diethanolamine hydrochloride is HSD17B4 (hydroxysteroid 17-beta dehydrogenase 4) and pregnane X receptor (PXR), p53 Estrogen receptor.Formula:C4H12ClNO2Purezza:99.69%Colore e forma:SolidPeso molecolare:141.6KOTX1
CAS:KOTX1 is an orally active and selective inhibitor of ALDH1A3. In a diabetic mouse model, KOTX1 improves glucose tolerance, insulin secretion, and blood glucose levels.Formula:C17H16FN3O2Colore e forma:SolidPeso molecolare:313.33hDHODH-IN-16
hDHODH-IN-16 (Compound 3t) is an inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an IC50 of 0.11 μM. It demonstrates very low cytotoxicity towards healthy HaCaT cells, with an IC50 value exceeding 200 μM.Formula:C18H20N2O2Colore e forma:SolidPeso molecolare:296.36Antiproliferative agent-13
CAS:Antiproliferative agent-13 is a compound with antiproliferative activity.Formula:C20H18N2O6Purezza:99.723%Colore e forma:SolidPeso molecolare:382.37Octanoyl Coenzyme A (sodium salt)
Octanoyl Coenzyme A (sodium salt) inhibits citrate synthase and glutamate dehydrogenase with an IC50 of 0.4–1.6 mM.Formula:C29H49N7NaO17P3SColore e forma:SolidPeso molecolare:915.71BMS-770767
CAS:BMS-770767 is a novel 11-betahydroxysteroid dehydrogenase type I (11ß-HSD1) inhibitor.Formula:C19H18ClN3O2Colore e forma:SolidPeso molecolare:355.82DHODH-IN-16
CAS:DHODH-IN-16 is an effective inhibitor of dihydroorotate dehydrogenase (DHODH, IC50 = 0.396 nM for human).Formula:C24H25FN4O3Purezza:99.64%Colore e forma:SolidPeso molecolare:436.48Ref: TM-T40168
1mg75,00€5mg169,00€10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta1mL*10mM (DMSO)180,00€HSD17B13-IN-89
CAS:HSD17B13-IN-89 (206) acts as an inhibitor of 17β-Hydroxysteroid dehydrogenases (HSD17B13) and demonstrates potent activity with an IC 50 value of less than 0.1 μM for Estradiol. It is commonly utilized in research related to Nonalcoholic Fatty Liver Diseases (NAFLD) [1].Formula:C23H13Cl2F4N3O3Peso molecolare:526.27PTOTAC HSD17B13 degrader 1
CAS:PTOTAC HSD17B13 Degrader 1, a PROTAC designed to target 17β-HSD 13 (HSD17B13), incorporates several key components. These include the PROTAC target protein ligand HSD17B13 Degrader 2, the PROTAC Linker tert-Butyl 5-bromoisoindoline-2-carboxylate, and the E3 ubiquitin ligase ligand E3 Ligase Ligand 31. Notably, the conjugate formed by the E3 ubiquitin ligase ligand and the linker is recognized as E3 Ligase Ligand-linker Conjugate 114.Formula:C45H45ClF3N7O5Colore e forma:SolidPeso molecolare:856.33Crelosidenib
CAS:Crelosidenib is a potent and selective mutant IDH inhibitor for IDH1 R132H, IDH1 R132C, IDH2 R140Q, and IDH2 R172K mutases.Formula:C28H36N6O3Purezza:98.54%Colore e forma:SolidPeso molecolare:504.6211β-HSD1 inibitor 19
CAS:3-chloro-4-sulfonyl-Benzonitrile inhibits hHSD1/mHSD1, IC50: 16nM/10nM.Formula:C19H16ClF4N3O2SPurezza:99.58%Colore e forma:SoildPeso molecolare:461.86SKI2852
CAS:SKI2852 is an 11β-HSD1 inhibitor that improves metabolic syndrome in diabetic mouse models.Formula:C27H34FN5O4SPurezza:99.89%Colore e forma:SolidPeso molecolare:543.65DHODH-IN-18
CAS:DHODH-IN-18 is a human DHODH inhibitor ( IC 50 = 0.2 nM).Formula:C21H16ClF5N6O4Colore e forma:SolidPeso molecolare:546.84MTHFD2-IN-4 sodium
MTHFD2-IN-4 sodium, a potent inhibitor of MTHFD2 and a tricyclic coumarin derivative, is applicable in cancer research [1].Formula:C26H21F6N2NaO5Colore e forma:SolidPeso molecolare:578.44D34-919
CAS:D34-919 is a potent inhibitor of the ALDH1A3-PKM2 interaction, effectively inhibiting the ALDH1A3-mediated tetramerization enhancement of PKM2. Treatment mediated by D34-919 both in vitro and in vivo enhances and restores apoptosis and sensitivity in glioblastoma (GBM) cells induced by radiochemotherapy.Formula:C22H27N5OSPeso molecolare:409.55LDHA-IN-8
CAS:LDHA-IN-8, an inhibitor, inhibits the proliferation of pancreatic and lung cancer cells, decreasing the intracellular lactate content and increasing ROS levels.Formula:C15H14N4O2Purezza:99.73%Colore e forma:SolidPeso molecolare:282.3MTHFD2-IN-1
<p>MTHFD2-IN-1 (compound 12) is a potent inhibitor of methylenetetrahydrofolate dehydrogenase (MTHFD2) [1].</p>Formula:C24H21NO6Colore e forma:SolidPeso molecolare:419.43MTHFD2-IN-4
MTHFD2-IN-4, a tricyclic coumarin derivative, serves as a potent inhibitor of MTHFD2 and has applications in cancer research [1].Formula:C26H21F6N2O5Colore e forma:SolidPeso molecolare:555.45DHODH-IN-23
CAS:<p>DHODH-IN-23 is a DHODH inhibitor with oral activity. DHODH-IN-23 is often used in cancer research.</p>Formula:C24H21ClFNO4Purezza:99.7%Colore e forma:SolidPeso molecolare:441.88IGUANA-1
CAS:IGUANA-1 is a highly efficient and selective ALDH1B1 inhibitor that inhibits the growth of colorectal cancer cells and colorectal cancer cell-derived organoids.Formula:C27H26ClN3O4Purezza:99.08%Colore e forma:SolidPeso molecolare:491.97Ref: TM-T73377
1mg86,00€5mg180,00€10mg283,00€25mg530,00€50mg797,00€100mg1.159,00€1mL*10mM (DMSO)188,00€D-Lactate dehydrogenase
CAS:D-LDH is an oxidoreductase turning D-lactate into pyruvate, using NAD+/NADP+; prevalent in bacteria and fungi, key for biochemical research.Colore e forma:SolidHSD17B13-IN-71
CAS:HSD17B13-IN-71 (Compound 149), an effective inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), displays potent activity with an IC 50 value of ≤ 0.1 μM against estradiol. This compound is applicable in the study of various disorders including liver diseases, metabolic diseases, and cardiovascular conditions such as NAFLD or NASH, in addition to drug-induced liver injury (DILI) [1].Formula:C25H16Cl2F5N3O4Peso molecolare:588.31hDHODH-IN-17
hDHODH-IN-17 (Compound 10) is an inhibitor of human dihydroorotate dehydrogenase (hDHODH), with an IC50 value of 0.188 μM. It fits well with the hDHODH active site and interacts effectively with amino acid residues. hDHODH-IN-17 is a potential broad-spectrum antiviral drug.11β-HSD1 inibitor 17
CAS:11β-HSD1 inibitor 17 is an inhibitor of 11β-hydroxysteroid dehydrogenase (11β-HSD1).Formula:C22H20F3N3O2SPurezza:99.26% - 99.72%Colore e forma:SoildPeso molecolare:447.47DSM1465
DSM1465 (Compound 82) is a potent and selective inhibitor of P. falciparum dihydroorotate dehydrogenase (PfDHODH) with an IC50 value of 15 nM. It inhibits P. falciparum 3D7 (Pf3D7) parasites with an EC50 value of 1.4 nM and demonstrates significant in vivo efficacy in humanized P. falciparum mouse models.Formula:C17H12ClF6N5O2Colore e forma:SolidPeso molecolare:467.753PDK-IN-1
CAS:PDK-IN-1, a PDK inhibitor, IC50: 0.03μM (PDK1), 0.1μM (HSP90), reduces tumor mass.Formula:C20H16BrN7OColore e forma:SolidPeso molecolare:450.29Necroptosis-IN-3
CAS:Necroptosis-IN-3 (Cyclohexanecarboxamide, N-(2-thienylmethyl)-) (Compound 69) is a Necroptosis inhibitor that inhibits TNF-α induced necroptosis.Formula:C12H17NOSPurezza:99.85%Colore e forma:SoildPeso molecolare:223.3311β-HSD1-IN-11
CAS:11β-HSd1-in-11 is a potent and competitive inhibitor of 11-β-hydroxysteroid dehydrogenase 1 (11β-HSD1) IN rats and humans with IC50 values of 0.34 μM and 0.13Formula:C15H11F3O3SPurezza:99.61%Colore e forma:SoildPeso molecolare:328.31Ref: TM-T60149
1mg115,00€5mg255,00€10mg375,00€25mg562,00€50mg787,00€100mg1.074,00€500mg2.157,00€1mL*10mM (DMSO)251,00€MTHFD2-IN-2
MTHFD2-IN-2 (compound 13) serves as a potent inhibitor of methylenetetrahydrofolate dehydrogenase (MTHFD2) [1].Formula:C22H18N4O5Colore e forma:SolidPeso molecolare:418.4Glucose dehydrogenase
CAS:Glucose dehydrogenase (GDH) is a redox enzyme typically occurring as dimeric or tetrameric proteins. GDH utilises external NAD or NADP to oxidise glucose .ALDH1A2-IN-1
CAS:ALDH1A2-IN-1 is a reversible active-site-directed ALDH1A2 inhibitor preventing spermatogenesis, useful in male contraceptive research.Formula:C21H26N4O4SPurezza:99.51%Colore e forma:SolidPeso molecolare:430.52Ref: TM-T39675
1mg52,00€5mg116,00€10mg182,00€25mg364,00€50mg567,00€100mg823,00€200mg1.111,00€1mL*10mM (DMSO)133,00€DSM265
CAS:DSM265 (PfSPZ) is a dihydroorotic acid dehydrogenase inhibitor with antimalarial activity.DSM265 can be used for the treatment of malaria infections.Formula:C14H12F7N5SPurezza:99.79%Colore e forma:SolidPeso molecolare:415.33DSM502
CAS:DSM502 DSM502 is a dihydroorotic acid dehydrogenase (DHODH) inhibitor with antimalarial activity that inhibits Plasmodium DHODH and can be used as a lead for antimalarial compounds.Formula:C16H16F3N3OPurezza:99.52%Colore e forma:SolidPeso molecolare:323.31Ref: TM-T40087
1mg87,00€5mg187,00€10mg301,00€25mg615,00€50mg900,00€100mg1.225,00€1mL*10mM (DMSO)207,00€Aldehyde dehydrogenase (NAD(P))
CAS:<p>ALDH catalyzes oxidation of aldehydes to acids, reducing NAD(P) to NAD(P)H, helping alleviate aldehyde stress.</p>Colore e forma:SolidKetogestin
CAS:Ketogestin is a progestational steroid and an inhibitor of enzyme 11β-hydroxysteroid dehydrogenase, and a weak negative modulator of GABAA receptors.Formula:C21H28O3Purezza:99.19%Colore e forma:SolidPeso molecolare:328.452-Bromoacetamide
CAS:2-Bromoacetamide (α-Bromoacetamide) is a class of disinfection by-products that exhibit developmental toxicity in animals.Formula:C2H4BrNOPurezza:99.83%Colore e forma:SolidPeso molecolare:137.96BMS-566419
CAS:BMS-566419: Acridinone-based IMPDH inhibitor for studying graft rejection.Formula:C28H30FN5O2Colore e forma:SolidPeso molecolare:487.57PKUMDL-WQ-2201
CAS:PKUMDL-WQ-2201 is a selective allosteric inhibitor of phosphoglycerate dehydrogenase (PHGDH) with Anti-tumor Activity, it binds to site II.Formula:C15H14ClN3O3SColore e forma:SolidPeso molecolare:351.81ALDH1A3-IN-1
CAS:ALDH1A3-IN-1 (Compound 14) is a potent inhibitor of ALDH1A3 which can be used in prostate cancer research (IC50 = 0.63 μM; Ki = 0.46 μM) [1].Formula:C13H18BrNOColore e forma:SolidPeso molecolare:284.19PS10
CAS:PS10 is a broad-spectrum PDK inhibitor that inhibits PDK2 and significantly increases the activity of the pyruvate dehydrogenase complex.Formula:C14H13NO6SPurezza:99.01%Colore e forma:SolidPeso molecolare:323.32ALDH3A1-IN-1
CAS:ALDH3A1-IN-1 (Compound 18) is a potent inhibitor of ALDH3A1 with IC50 of 1.61 μM, outperforms DEAB in prostate cancer cells.Formula:C13H18N2O3Purezza:99.86%Colore e forma:SolidPeso molecolare:250.294-Isopropoxybenzaldehyde
CAS:ALDH1A3-IN-3 inhibits ALDH1A3 (IC50: 0.26 μM), acts on ALDH3A1, and is used in prostate cancer research.Formula:C10H12O2Purezza:99.00%Colore e forma:SolidPeso molecolare:164.2ABT-384
CAS:ABT-384 is a high-affinity, selective 11β-HSD1 inhibitor capable of suppressing hepatic and central nervous system HSD-1 activity for depressive disorder.Formula:C25H34F3N5O2Purezza:99.863%Colore e forma:SolidPeso molecolare:493.58Ref: TM-T26528
1mg115,00€5mg274,00€10mg455,00€25mg847,00€50mg1.311,00€100mg2.043,00€200mg2.737,00€1mL*10mM (DMSO)298,00€VER-246608
CAS:VER-246608 inhibits PDK (IC50: 35-91 nM), boosts PDC, reduces glycolysis, causes cancer cell cytostasis, and enhances doxorubicin effects.Formula:C28H23ClF2N4O4Purezza:98.5%Colore e forma:SolidPeso molecolare:552.96Ref: TM-T17224
1mg52,00€2mg74,00€5mg111,00€10mg170,00€25mg329,00€50mg502,00€100mg730,00€1mL*10mM (DMSO)137,00€Brequinar
CAS:Brequinar (NSC-368390) is a potent inhibitor of dihydroorotate dehydrogenase, with potent activities against a broad spectrum of viruses.Formula:C23H15F2NO2Purezza:99.1% - 99.57%Colore e forma:SolidPeso molecolare:375.37BVT 2733
CAS:<p>BVT 2733 is a new, non-steroidal, isoform-specific inhibitor of 11β-HSD1.</p>Formula:C17H21ClN4O3S2Purezza:98% - 99.64%Colore e forma:SolidPeso molecolare:428.96AGI-6780
CAS:AGI-6780 is a potent and selective inhibitor of IDH2 R140Q mutant.Formula:C21H18F3N3O3S2Purezza:98.19% - 99.7%Colore e forma:SolidPeso molecolare:481.51Ref: TM-T1809
1mg37,00€2mg52,00€5mg79,00€10mg119,00€25mg220,00€50mg393,00€100mg587,00€500mg1.264,00€1mL*10mM (DMSO)85,00€(E/Z)-Teriflunomide
CAS:(E/Z)-Teriflunomide (Aubagio), a orally-available Pyrimidine Synthesis Inhibitor, is used to treat relapsing multiple sclerosis.Formula:C12H9F3N2O2Purezza:99.49% - 99.76%Colore e forma:White SolidPeso molecolare:270.21Nitrofurazone
CAS:Nitrofurazone (Furacilin) is a topical anti-infective agent effective against gram-negative and gram-positive bacteria.Formula:C6H6N4O4Purezza:99.87%Colore e forma:Pale Yellow Needles Solution) 6 0 - 6 5 Alkaline Solutions Are Dark Orange (Ntp 1992)Peso molecolare:198.14Galloflavin
CAS:Galloflavin is a lactate dehydrogenase inhibitor. Galloflavin inhibits both human LDH isoforms (type A and type B).Cost-effective and quality-assured.Formula:C12H6O8Purezza:96.24% - 97.47%Colore e forma:SolidPeso molecolare:278.17NCT-505
CAS:NCT-505 is a potent and selective inhibitor of aldehyde dehydrogenase (ALDH1A1, IC50 = 7 nM) and a weak inhibitor of hALDH1A2, hALDH1A3, hALDH2, hALDH3A1 withFormula:C27H28FN5O3SPurezza:99.93%Colore e forma:SolidPeso molecolare:521.61Ref: TM-T12196
1mg115,00€5mg235,00€10mg353,00€25mg562,00€50mg758,00€100mg1.017,00€200mg1.359,00€1mL*10mM (DMSO)270,00€R162
CAS:R162 is an effective glutamate dehydrogenase 1 (GDH1) inhibitor.Formula:C17H12O3Purezza:96.21% - 98.15%Colore e forma:SolidPeso molecolare:264.28PfDHODH-IN-2
CAS:PfDHODH-IN-2: powerful antimalarial, blocks PfDHODH (IC50: 1.11 μM), for malaria research.Formula:C13H12ClNO3SPurezza:98.9%Colore e forma:SolidPeso molecolare:297.76Ref: TM-T8767
1mg48,00€5mg97,00€10mg145,00€25mg259,00€50mg383,00€100mg545,00€200mg740,00€1mL*10mM (DMSO)105,00€
