Deidrogenasi
Le deidrogenasi sono enzimi coinvolti nelle reazioni di ossidoriduzione delle vie metaboliche, svolgendo un ruolo centrale nella produzione di energia e nella respirazione cellulare. Questi enzimi sono cruciali per processi come il ciclo dell'acido citrico, la glicolisi e l'ossidazione degli acidi grassi. Gli inibitori delle deidrogenasi sono strumenti importanti nello studio delle malattie metaboliche, del cancro e dello stress ossidativo. Presso CymitQuimica, offriamo una selezione completa di inibitori delle deidrogenasi per supportare la tua ricerca in metabolismo, biologia del cancro e biochimica.
Trovati 302 prodotti di "Deidrogenasi"
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CVT-10216
CAS:CVT-10216 inhibits ALDH2 (IC50: 29 nM) and ALDH-1 (IC50: 1.3 μM), reducing alcohol intake and anxiety in rats.Formula:C24H19NO7SPurezza:98.76%Colore e forma:SolidPeso molecolare:465.48PTC299
CAS:PTC299 ((4-chlorophenyl) (1S)-6-chloro-1-(4-methoxyphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carboxylate) is an orally active inhibitor of VEGFA mRNAFormula:C25H20Cl2N2O3Purezza:99.72%Colore e forma:SolidPeso molecolare:467.34Ref: TM-T12574
1mg117,00€5mg243,00€10mg369,00€25mg622,00€50mg885,00€100mg1.206,00€1mL*10mM (DMSO)250,00€ML390
CAS:<p>ML390 exerts its potent differentiation effect on multiple leukemia models.</p>Formula:C21H21F3N2O3Purezza:99.76%Colore e forma:SolidPeso molecolare:406.4RS 61443
CAS:RS 61443 (Mycophenolate mofetil) is an immunosuppressant, a non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH)Formula:C23H31NO7Purezza:99.37% - 99.96%Colore e forma:SolidPeso molecolare:433.5CAY10566
CAS:CAY10566 is a potent SCD1 inhibitor, orally bioavailable, with IC50s: HepG2 cells, 7.9nM; mouse, 4.5nM; human, 26nM.Formula:C18H17ClFN5O2Purezza:99.5% - 99.54%Colore e forma:SolidPeso molecolare:389.81Ref: TM-T14878
1mg50,00€5mg138,00€10mg205,00€25mg373,00€50mg533,00€100mg748,00€200mg1.008,00€1mL*10mM (DMSO)118,00€XEN723
CAS:XEN723 is a potent thiazolylimidazolidinone Stearoyl-CoA Desaturase (SCD1) inhibitor(IC50s of 45 and 524 nM in mouse and HepG2 cell, respectively).Formula:C21H20FN5O2SPurezza:99.5%Colore e forma:SolidPeso molecolare:425.48Ref: TM-T13356
1mg55,00€5mg116,00€10mg178,00€25mg304,00€50mg437,00€100mg615,00€200mg830,00€1mL*10mM (DMSO)139,00€Mutant IDH1 inhibitor
CAS:Mutant IDH1 inhibitor is an effective inhibitor of mutant IDH1 R132H (IC50: < 72 nM).Formula:C25H34N6O3Purezza:98.3%Colore e forma:SolidPeso molecolare:466.58Ref: TM-T16161
1mg42,00€5mg90,00€10mg135,00€25mg221,00€50mg324,00€100mg452,00€200mg630,00€1mL*10mM (DMSO)94,00€KPLH1130
CAS:<p>KPLH1130, a PDK inhibitor, boosts glucose tolerance and reduces inflammation in high-fat diet mice.</p>Formula:C15H13N3O3Purezza:99.07%Colore e forma:SolidPeso molecolare:283.28BAY-2402234
CAS:BAY-2402234: a selective DHODH inhibitor targeting myeloid cancers with low-nanomolar potency.Formula:C21H18ClF5N4O4Purezza:98.9%Colore e forma:SolidPeso molecolare:520.84Ref: TM-T14501
1mg173,00€2mg246,00€5mg368,00€10mg567,00€25mg905,00€50mg1.225,00€100mg1.644,00€1mL*10mM (DMSO)424,00€GSK2837808A
CAS:GSK2837808A is a potent and selective inhibitor of lactate dehydrogenase A (LDHA) (IC50s: 1.9 and 14 nM for LDHA and LDHB, respectively).Formula:C31H25F2N5O7SPurezza:99.78% - 99.78%Colore e forma:SolidPeso molecolare:649.62Ref: TM-T15435
1mg48,00€5mg111,00€10mg170,00€25mg329,00€50mg455,00€100mg645,00€1mL*10mM (DMSO)159,00€4-Diethylaminobenzaldehyde
CAS:<p>4-Diethylaminobenzaldehyde: reversible ALDH1 inhibitor (Ki: 4 nM), potent anti-androgen (IC50: 1.71μM).</p>Formula:C11H15NOPurezza:99.6%Colore e forma:Brown-Black CrystalsPeso molecolare:177.24DHODH-IN-11
CAS:DHODH-IN-11 is a leflunomide derivative and weak dihydroorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.03.Formula:C15H11N3O2Purezza:98.14%Colore e forma:SolidPeso molecolare:265.27MF-438
CAS:MF-438 is an effective and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor (EC50: 2.3 nM for rSCD1).Formula:C19H18F3N5OSPurezza:98.98% - 99.50%Colore e forma:SolidPeso molecolare:421.44Ref: TM-T16068
1mg97,00€2mg144,00€5mg215,00€10mg328,00€25mg557,00€50mg797,00€100mg1.103,00€500mg2.205,00€1mL*10mM (DMSO)235,00€Trilostane
CAS:Trilostane (Win 24540) is a synthetic derivative of androstane with adrenocortical suppressive properties.Formula:C20H27NO3Purezza:99.46% - >99.99%Colore e forma:Tan CrystalsPeso molecolare:329.43CBR-5884
CAS:CBR-5884: active PHGDH inhibitor, IC50=33μM, disrupts serine synthesis, selectively targets high-serine cancers.Formula:C14H12N2O4S2Purezza:99.97%Colore e forma:SolidPeso molecolare:336.39LY 345899
CAS:<p>LY 345899 is a Folate analog and is a methylenetetrahydrofolate dehydrogenase and MTHFD2 inhibitor (IC50: 96 nM and 663 nM, respectively and a Ki: 18 nM for</p>Formula:C20H21N7O7Purezza:99.7%Colore e forma:SolidPeso molecolare:471.42IDH-305
CAS:IDH-305: Oral, mutation-specific IDH1 inhibitor, 200x selective for R132 mutants; IC50: 27/28/6.14 nM for R132H/C/WT.Formula:C23H22F4N6O2Purezza:99.68%Colore e forma:SolidPeso molecolare:490.45NCT-502
CAS:NCT-502 (N-(4,6-dimethylpyridin-2-yl)-4-[5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carbothioamide) is a human phosphoglycerate dehydrogenase inhibitor,Formula:C18H20F3N5SPurezza:99.60%Colore e forma:SolidPeso molecolare:395.45Ref: TM-T16277
2mg39,00€5mg57,00€10mg87,00€25mg159,00€50mg240,00€100mg415,00€500mg933,00€1mL*10mM (DMSO)63,00€SCD1 inhibitor-4
CAS:<p>SCD1 inhibitor-4 is stearoylCoA desaturase-1 (SCD1) inhibitor. SCD1 inhibitor-4 can be used for the research of diabetes.</p>Formula:C17H16F3N5OPurezza:99.71%Colore e forma:SolidPeso molecolare:363.34Adrenosterone
CAS:Adrenosterone (11-ketoandrostenedione) is a steroid hormone isolated from the adrenal cortex.Formula:C19H24O3Purezza:98.13% - 98.29%Colore e forma:SolidPeso molecolare:300.39LDH-IN-1
CAS:LDH-IN-1 is a pyrazole-based human lactate dehydrogenase (LDH) inhibitor(IC50s of 32 and 27 nM for LDHA and LDHB, respectively).Formula:C30H26N4O4S2Purezza:99.6%Colore e forma:SolidPeso molecolare:570.68Ref: TM-T11829
1mg188,00€5mg393,00€10mg588,00€25mg938,00€50mg1.359,00€100mg1.786,00€200mg2.442,00€1mL*10mM (DMSO)494,00€Mycophenolic acid
CAS:Mycophenolic acid (Mycophenolate) is an inosine monophosphate dehydrogenase(IMPDH) inhibitor with anti-proliferative activity.Formula:C17H20O6Purezza:98.79% - 99.77%Colore e forma:SolidPeso molecolare:320.34Olutasidenib
CAS:Olutasidenib (FT-2102), an IDH1 inhibitor (IC50: 21.2/114 nM), is studied for treating AML/MDS and can cross the blood-brain barrier.Formula:C18H15ClN4O2Purezza:98.57%Colore e forma:SolidPeso molecolare:354.79Ref: TM-T16384
1mg62,00€5mg169,00€10mg264,00€25mg487,00€50mg710,00€100mg998,00€200mg1.320,00€1mL*10mM (DMSO)178,00€IGUANA-1
CAS:IGUANA-1 is a highly efficient and selective ALDH1B1 inhibitor that inhibits the growth of colorectal cancer cells and colorectal cancer cell-derived organoids.Formula:C27H26ClN3O4Purezza:99.08%Colore e forma:SolidPeso molecolare:491.97Ref: TM-T73377
1mg86,00€5mg180,00€10mg283,00€25mg530,00€50mg797,00€100mg1.159,00€1mL*10mM (DMSO)188,00€BMS-337197
CAS:BMS-337197 is an IMPDH inhibitor.Formula:C26H27N5O5Colore e forma:SoildPeso molecolare:489.52Crelosidenib
CAS:Crelosidenib is a potent and selective mutant IDH inhibitor for IDH1 R132H, IDH1 R132C, IDH2 R140Q, and IDH2 R172K mutases.Formula:C28H36N6O3Purezza:98.54%Colore e forma:SolidPeso molecolare:504.62DSM705
CAS:DSM705: Pyrrole-based, potent nanomolar Plasmodium DHODH inhibitor with strong antimalarial efficacy; spares mammalian DHODH.Formula:C19H19F3N6OColore e forma:SolidPeso molecolare:404.397WQQ-345
WQQ-345, a BCAT1 inhibitor, exhibits an IC50 of 10.8 mM. In 67R cells, it reduces α-KG levels and upregulates H3K27me3 expression while downregulating the expression of glycolytic enzymes (PFKP and LDHA), leading to impaired glycolytic activity. Additionally, WQQ-345 demonstrates tumor-suppressive activity in a 67R subcutaneous xenograft model.Formula:C10H17NO2Colore e forma:SolidPeso molecolare:183.25SKI2852
CAS:SKI2852 is an 11β-HSD1 inhibitor that improves metabolic syndrome in diabetic mouse models.Formula:C27H34FN5O4SPurezza:99.89%Colore e forma:SolidPeso molecolare:543.65KOTX1
CAS:KOTX1 is an orally active and selective inhibitor of ALDH1A3. In a diabetic mouse model, KOTX1 improves glucose tolerance, insulin secretion, and blood glucose levels.Formula:C17H16FN3O2Colore e forma:SolidPeso molecolare:313.33hDHODH-IN-16
hDHODH-IN-16 (Compound 3t) is an inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an IC50 of 0.11 μM. It demonstrates very low cytotoxicity towards healthy HaCaT cells, with an IC50 value exceeding 200 μM.Formula:C18H20N2O2Colore e forma:SolidPeso molecolare:296.36BVT-2733 hydrochloride
CAS:BVT-2733 hydrochloride is a potent, selective, and orally active non-steroidal 11β-HSD1 inhibitor. It exhibits stronger inhibition on mouse 11β-HSD1 enzyme (IC50=96 nM) compared to the human 11β-HSD1 enzyme (IC50=3341 nM). BVT-2733 hydrochloride shows potential for research in arthritis and obesity-related diseases.Formula:C17H22Cl2N4O3S2Colore e forma:SolidPeso molecolare:465.42Osmanthuside H
CAS:Osmanthuside H is a useful organic compound for research related to life sciences. The catalog number is T125796 and the CAS number is 149155-70-4.Formula:C19H28O11Colore e forma:SolidPeso molecolare:432.422MCI-INI-3
CAS:MCI-INI-3 is a selective competitive inhibitor of human ALDH1A3, with a Ki value of 0.55 μM for ALDH1A3 and 78.2 μM for ALDH1A1. It inhibits retinoic acid biosynthesis and can reduce the viability of glioblastoma cells GSC-83 and GSC-326.Formula:C21H15N3O4Colore e forma:SolidPeso molecolare:373.36hDHODH-IN-12
hDHODH-IN-12 is a potent inhibitor of dihydroorotate dehydrogenase (DHODH), exhibiting an inhibitory concentration (IC50) of 0.421 μM.Formula:C22H15F3N4O3Purezza:98%Colore e forma:SolidPeso molecolare:440.37(Rac)-BMS-816336
(Rac)-BMS-816336 is a racemic 11β-HSD1 inhibitor; IC50: 10 nM (human), 68 nM (mouse), metabolically stable.Formula:C21H27NO3Purezza:98%Colore e forma:SolidPeso molecolare:341.44Octanoyl Coenzyme A (sodium salt)
Octanoyl Coenzyme A (sodium salt) inhibits citrate synthase and glutamate dehydrogenase with an IC50 of 0.4–1.6 mM.Formula:C29H49N7NaO17P3SColore e forma:SolidPeso molecolare:915.7111β-HSD1 inibitor 17
CAS:11β-HSD1 inibitor 17 is an inhibitor of 11β-hydroxysteroid dehydrogenase (11β-HSD1).Formula:C22H20F3N3O2SPurezza:99.26% - 99.72%Colore e forma:SoildPeso molecolare:447.47MTHFD2-IN-4 sodium
MTHFD2-IN-4 sodium, a potent inhibitor of MTHFD2 and a tricyclic coumarin derivative, is applicable in cancer research [1].Formula:C26H21F6N2NaO5Colore e forma:SolidPeso molecolare:578.44hDHODH-IN-13
CAS:hDHODH-IN-13 (compound w2), an inhibitor of human dihydroorotate dehydrogenase (hDHODH), exhibits an IC50 of 173.4 nM and has potential research applications inColore e forma:SoildMTHFD2-IN-4
MTHFD2-IN-4, a tricyclic coumarin derivative, serves as a potent inhibitor of MTHFD2 and has applications in cancer research [1].Formula:C26H21F6N2O5Colore e forma:SolidPeso molecolare:555.45IGUANA-1 free base
CAS:IGUANA-1: selective ALDH1 B1 inhibitor, IC50=30 nM, hinders SW480 cell growth with IC50=2.46/0.39 μM in adherent/spheroid forms, for cancer research.Formula:C26H24ClN3O2Colore e forma:SolidPeso molecolare:445.94PDK-IN-1
CAS:PDK-IN-1, a PDK inhibitor, IC50: 0.03μM (PDK1), 0.1μM (HSP90), reduces tumor mass.Formula:C20H16BrN7OColore e forma:SolidPeso molecolare:450.29MTHFD2-IN-2
MTHFD2-IN-2 (compound 13) serves as a potent inhibitor of methylenetetrahydrofolate dehydrogenase (MTHFD2) [1].Formula:C22H18N4O5Colore e forma:SolidPeso molecolare:418.4D-Lactate dehydrogenase
CAS:D-LDH is an oxidoreductase turning D-lactate into pyruvate, using NAD+/NADP+; prevalent in bacteria and fungi, key for biochemical research.Colore e forma:SolidNecroptosis-IN-3
CAS:Necroptosis-IN-3 (Cyclohexanecarboxamide, N-(2-thienylmethyl)-) (Compound 69) is a Necroptosis inhibitor that inhibits TNF-α induced necroptosis.Formula:C12H17NOSPurezza:99.85%Colore e forma:SoildPeso molecolare:223.33CM121
CAS:CM121, a reversible ALDH1A2 inhibitor, targets active site with IC50=0.54μM, Kd=1.1μM, using hydrophobic interactions.Formula:C24H17FN4O3SColore e forma:SolidPeso molecolare:460.48MTHFD2-IN-1
<p>MTHFD2-IN-1 (compound 12) is a potent inhibitor of methylenetetrahydrofolate dehydrogenase (MTHFD2) [1].</p>Formula:C24H21NO6Colore e forma:SolidPeso molecolare:419.43DHODH-IN-18
CAS:DHODH-IN-18 is a human DHODH inhibitor ( IC 50 = 0.2 nM).Formula:C21H16ClF5N6O4Colore e forma:SolidPeso molecolare:546.84DSM1465
DSM1465 (Compound 82) is a potent and selective inhibitor of P. falciparum dihydroorotate dehydrogenase (PfDHODH) with an IC50 value of 15 nM. It inhibits P. falciparum 3D7 (Pf3D7) parasites with an EC50 value of 1.4 nM and demonstrates significant in vivo efficacy in humanized P. falciparum mouse models.Formula:C17H12ClF6N5O2Colore e forma:SolidPeso molecolare:467.75318β-Glycyrrhetyl-3-O-sulfate
CAS:18β-Glycyrrhetyl-3-O-sulfate (Glycyrrhetic acid 3-O-(hydrogen sulfate)), a major metabolite of Glycyrrhetinic acid (GA), serves as a potent inhibitor of type 2Formula:C30H46O7SColore e forma:SolidPeso molecolare:550.7511β-HSD1-IN-11
CAS:11β-HSd1-in-11 is a potent and competitive inhibitor of 11-β-hydroxysteroid dehydrogenase 1 (11β-HSD1) IN rats and humans with IC50 values of 0.34 μM and 0.13Formula:C15H11F3O3SPurezza:99.61%Colore e forma:SoildPeso molecolare:328.31Ref: TM-T60149
1mg115,00€5mg255,00€10mg375,00€25mg562,00€50mg787,00€100mg1.074,00€500mg2.157,00€1mL*10mM (DMSO)251,00€PDK-IN-2
PDK-IN-2 (Compound 1F), with an IC50 of 68 nM, is a potent PDK inhibitor that downregulates the expression of PDK1 and PDK4 in cells.Formula:C17H23AsCl2N2O2S2Colore e forma:SolidPeso molecolare:497.33BMS-770767
CAS:BMS-770767 is a novel 11-betahydroxysteroid dehydrogenase type I (11ß-HSD1) inhibitor.Formula:C19H18ClN3O2Colore e forma:SolidPeso molecolare:355.822,3-Dihydroxybenzaldehyde
CAS:2,3-Dihydroxybenzaldehyde exhibits activity against NADH dehydrogenase (Km = 35 µM) and can be used in biochemical experiments and drug synthesis.Formula:C7H6O3Colore e forma:SolidPeso molecolare:138.12MTHFD2-IN-3
MTHFD2-IN-3 (compound 10), a potent inhibitor of methylenetetrahydrofolate dehydrogenase (MTHFD2), demonstrates significant efficacy in obstructing the activityFormula:C22H19NO7SColore e forma:SolidPeso molecolare:441.45Nedosiran sodium
CAS:<p>Nedosiran sodium, a GalNAc-dsRNA conjugate, is engineered to suppress the synthesis of the hepatic lactate dehydrogenase (LDH) enzyme.</p>Colore e forma:SolidAscochlorin A
CAS:Ascochlorin A, a compound with a dissociation constant (K D) of 3.29 μM, serves as a novel and potent human dihydroorotate dehydrogenase (hDHODH) inhibitorFormula:C23H31ClO4Colore e forma:SolidPeso molecolare:406.9517β-HSD10-IN-1
CAS:17β-HSD10-IN-1 is a 17β-hydroxysteroid dehydrogenase type 10 inhibitor with blood-brain permeability and potency for the study of Alzheimer's disease.Formula:C16H13ClN4O3SPurezza:98.47%Colore e forma:SoildPeso molecolare:376.82SCD1 inhibitor-3
CAS:SCD1 inhibitor-3 (ML-270) is a highly effective and orally available compound that inhibits SCD1 with remarkable safety.Formula:C19H16FN7O2Purezza:99.5%Colore e forma:SolidPeso molecolare:393.37Ref: TM-T38683
1mg92,00€5mg187,00€10mg298,00€25mg507,00€50mg730,00€100mg1.026,00€1mL*10mM (DMSO)205,00€TC HSD 21
CAS:TC HSD 21 is a potent and highly selective inhibitor of 17β-hydroxysteroid dehydrogenase type 3 (IC50 = 14 nM).Formula:C17H12BrNO3S2Purezza:99.32%Colore e forma:SolidPeso molecolare:422.32Ref: TM-T13100
1mg42,00€5mg90,00€10mg137,00€25mg239,00€50mg344,00€100mg462,00€200mg625,00€1mL*10mM (DMSO)90,00€SW209049
CAS:SW209049 is a stearoyl-CoA 9-desaturase inhibitor. SW209049 exhivits potent activity against H2122 cell with IC50 of 0.13uM.Formula:C25H18N2O4SPurezza:99.72%Colore e forma:SolidPeso molecolare:442.49Ref: TM-T9859
1mg77,00€5mg158,00€10mg225,00€25mg338,00€50mg475,00€100mg638,00€200mg845,00€1mL*10mM (DMSO)170,00€Antiproliferative agent-13
CAS:Antiproliferative agent-13 is a compound with antiproliferative activity.Formula:C20H18N2O6Purezza:99.723%Colore e forma:SolidPeso molecolare:382.37WAY-311610
CAS:WAY-311610 is an HSD11B1 inhibitor targeting 11β-HSD1 enzyme with 0.34 μM IC; used for neuropathic and inflammatory pain research.Formula:C16H13F3N4O2Purezza:99.75%Colore e forma:SolidPeso molecolare:350.3Diethanolamine hydrochloride
CAS:Diethanolamine hydrochloride is HSD17B4 (hydroxysteroid 17-beta dehydrogenase 4) and pregnane X receptor (PXR), p53 Estrogen receptor.Formula:C4H12ClNO2Purezza:99.69%Colore e forma:SolidPeso molecolare:141.6DHODH-IN-23
CAS:<p>DHODH-IN-23 is a DHODH inhibitor with oral activity. DHODH-IN-23 is often used in cancer research.</p>Formula:C24H21ClFNO4Purezza:99.7%Colore e forma:SolidPeso molecolare:441.88DHODH-IN-16
CAS:DHODH-IN-16 is an effective inhibitor of dihydroorotate dehydrogenase (DHODH, IC50 = 0.396 nM for human).Formula:C24H25FN4O3Purezza:99.64%Colore e forma:SolidPeso molecolare:436.48Ref: TM-T40168
1mg75,00€5mg169,00€10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta1mL*10mM (DMSO)180,00€hDHODH-IN-8
CAS:hDHODH-IN-8: potent hDHODH inhibitor, IC50 = 16 nM, antiproliferative, soluble, may research lymphoma.Formula:C21H15F6N3O4Purezza:98%Colore e forma:SoildPeso molecolare:487.3511β-HSD1 inibitor 19
CAS:3-chloro-4-sulfonyl-Benzonitrile inhibits hHSD1/mHSD1, IC50: 16nM/10nM.Formula:C19H16ClF4N3O2SPurezza:99.58%Colore e forma:SoildPeso molecolare:461.86HSD17B13-IN-89
CAS:HSD17B13-IN-89 (206) acts as an inhibitor of 17β-Hydroxysteroid dehydrogenases (HSD17B13) and demonstrates potent activity with an IC 50 value of less than 0.1 μM for Estradiol. It is commonly utilized in research related to Nonalcoholic Fatty Liver Diseases (NAFLD) [1].Formula:C23H13Cl2F4N3O3Peso molecolare:526.27PTOTAC HSD17B13 degrader 1
CAS:PTOTAC HSD17B13 Degrader 1, a PROTAC designed to target 17β-HSD 13 (HSD17B13), incorporates several key components. These include the PROTAC target protein ligand HSD17B13 Degrader 2, the PROTAC Linker tert-Butyl 5-bromoisoindoline-2-carboxylate, and the E3 ubiquitin ligase ligand E3 Ligase Ligand 31. Notably, the conjugate formed by the E3 ubiquitin ligase ligand and the linker is recognized as E3 Ligase Ligand-linker Conjugate 114.Formula:C45H45ClF3N7O5Colore e forma:SolidPeso molecolare:856.33hDHODH-IN-17
hDHODH-IN-17 (Compound 10) is an inhibitor of human dihydroorotate dehydrogenase (hDHODH), with an IC50 value of 0.188 μM. It fits well with the hDHODH active site and interacts effectively with amino acid residues. hDHODH-IN-17 is a potential broad-spectrum antiviral drug.LDHA-IN-3
CAS:LDHA-IN-3 is a potent selenobenzene-based LDHA inhibitor with a 145.2 nM IC50, useful in cancer research.Formula:C13H9F3SePurezza:99.71%Colore e forma:SolidPeso molecolare:301.17Ref: TM-T39805
1mg55,00€5mg119,00€10mg187,00€25mg393,00€50mg547,00€100mg747,00€200mg1.026,00€1mL*10mM (DMSO)131,00€D34-919
CAS:D34-919 is a potent inhibitor of the ALDH1A3-PKM2 interaction, effectively inhibiting the ALDH1A3-mediated tetramerization enhancement of PKM2. Treatment mediated by D34-919 both in vitro and in vivo enhances and restores apoptosis and sensitivity in glioblastoma (GBM) cells induced by radiochemotherapy.Formula:C22H27N5OSPeso molecolare:409.55HSD17B13-IN-71
CAS:HSD17B13-IN-71 (Compound 149), an effective inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), displays potent activity with an IC 50 value of ≤ 0.1 μM against estradiol. This compound is applicable in the study of various disorders including liver diseases, metabolic diseases, and cardiovascular conditions such as NAFLD or NASH, in addition to drug-induced liver injury (DILI) [1].Formula:C25H16Cl2F5N3O4Peso molecolare:588.31LDHA-IN-8
CAS:LDHA-IN-8, an inhibitor, inhibits the proliferation of pancreatic and lung cancer cells, decreasing the intracellular lactate content and increasing ROS levels.Formula:C15H14N4O2Purezza:99.73%Colore e forma:SolidPeso molecolare:282.3DSM502
CAS:DSM502 DSM502 is a dihydroorotic acid dehydrogenase (DHODH) inhibitor with antimalarial activity that inhibits Plasmodium DHODH and can be used as a lead for antimalarial compounds.Formula:C16H16F3N3OPurezza:99.52%Colore e forma:SolidPeso molecolare:323.31Ref: TM-T40087
1mg87,00€5mg187,00€10mg301,00€25mg615,00€50mg900,00€100mg1.225,00€1mL*10mM (DMSO)207,00€ABT-384
CAS:ABT-384 is a high-affinity, selective 11β-HSD1 inhibitor capable of suppressing hepatic and central nervous system HSD-1 activity for depressive disorder.Formula:C25H34F3N5O2Purezza:99.863%Colore e forma:SolidPeso molecolare:493.58Ref: TM-T26528
1mg115,00€5mg274,00€10mg455,00€25mg847,00€50mg1.311,00€100mg2.043,00€200mg2.737,00€1mL*10mM (DMSO)298,00€PKUMDL-WQ-2201
CAS:PKUMDL-WQ-2201 is a selective allosteric inhibitor of phosphoglycerate dehydrogenase (PHGDH) with Anti-tumor Activity, it binds to site II.Formula:C15H14ClN3O3SColore e forma:SolidPeso molecolare:351.81PS10
CAS:PS10 is a broad-spectrum PDK inhibitor that inhibits PDK2 and significantly increases the activity of the pyruvate dehydrogenase complex.Formula:C14H13NO6SPurezza:99.01%Colore e forma:SolidPeso molecolare:323.32Aldehyde dehydrogenase (NAD(P))
CAS:<p>ALDH catalyzes oxidation of aldehydes to acids, reducing NAD(P) to NAD(P)H, helping alleviate aldehyde stress.</p>Colore e forma:SolidALDH3A1-IN-1
CAS:ALDH3A1-IN-1 (Compound 18) is a potent inhibitor of ALDH3A1 with IC50 of 1.61 μM, outperforms DEAB in prostate cancer cells.Formula:C13H18N2O3Purezza:99.86%Colore e forma:SolidPeso molecolare:250.29ALDH1A3-IN-1
CAS:ALDH1A3-IN-1 (Compound 14) is a potent inhibitor of ALDH1A3 which can be used in prostate cancer research (IC50 = 0.63 μM; Ki = 0.46 μM) [1].Formula:C13H18BrNOColore e forma:SolidPeso molecolare:284.194-Isopropoxybenzaldehyde
CAS:ALDH1A3-IN-3 inhibits ALDH1A3 (IC50: 0.26 μM), acts on ALDH3A1, and is used in prostate cancer research.Formula:C10H12O2Purezza:99.00%Colore e forma:SolidPeso molecolare:164.2Glucose dehydrogenase
CAS:Glucose dehydrogenase (GDH) is a redox enzyme typically occurring as dimeric or tetrameric proteins. GDH utilises external NAD or NADP to oxidise glucose .ALDH1A2-IN-1
CAS:ALDH1A2-IN-1 is a reversible active-site-directed ALDH1A2 inhibitor preventing spermatogenesis, useful in male contraceptive research.Formula:C21H26N4O4SPurezza:99.51%Colore e forma:SolidPeso molecolare:430.52Ref: TM-T39675
1mg52,00€5mg116,00€10mg182,00€25mg364,00€50mg567,00€100mg823,00€200mg1.111,00€1mL*10mM (DMSO)133,00€BMS-566419
CAS:BMS-566419: Acridinone-based IMPDH inhibitor for studying graft rejection.Formula:C28H30FN5O2Colore e forma:SolidPeso molecolare:487.572-Bromoacetamide
CAS:2-Bromoacetamide (α-Bromoacetamide) is a class of disinfection by-products that exhibit developmental toxicity in animals.Formula:C2H4BrNOPurezza:99.83%Colore e forma:SolidPeso molecolare:137.96Ketogestin
CAS:Ketogestin is a progestational steroid and an inhibitor of enzyme 11β-hydroxysteroid dehydrogenase, and a weak negative modulator of GABAA receptors.Formula:C21H28O3Purezza:99.19%Colore e forma:SolidPeso molecolare:328.45DSM265
CAS:DSM265 (PfSPZ) is a dihydroorotic acid dehydrogenase inhibitor with antimalarial activity.DSM265 can be used for the treatment of malaria infections.Formula:C14H12F7N5SPurezza:99.79%Colore e forma:SolidPeso molecolare:415.33(E/Z)-Teriflunomide
CAS:(E/Z)-Teriflunomide (Aubagio), a orally-available Pyrimidine Synthesis Inhibitor, is used to treat relapsing multiple sclerosis.Formula:C12H9F3N2O2Purezza:99.49% - 99.76%Colore e forma:White SolidPeso molecolare:270.21Proguanil hydrochloride
CAS:Proguanil hydrochloride, a biguanide, metabolizes into cycloguanil, an anti-malaria agent that inhibits plasmodium's DNA and protein synthesis.Formula:C11H17Cl2N5Purezza:98.34% - 98.39%Colore e forma:SolidPeso molecolare:290.19Succinyl phosphonate trisodium salt
CAS:Succinyl phosphonate trisodium salt is an inhibitor of α-ketoglutarate dehydrogenase (KGDHC)Formula:C4H4Na3O6PPurezza:99.8% - ≥95%Colore e forma:SolidPeso molecolare:248.01Nifurtimox
CAS:Nifurtimox (BAY-A-2502) is an antiprotozoal agent (IC50s = 9.91, 12.28, and 10.44 μM against Taluahuén, LQ, and Brener strains of T.Formula:C10H13N3O5SPurezza:99.87% - 99.89%Colore e forma:SolidPeso molecolare:287.29Carbenoxolone disodium
CAS:Carbenoxolone disodium treats stomach ulcers; derived from licorice, often has antidiuretic effects, low toxicity.Formula:C34H48Na2O7Purezza:99.69%Colore e forma:SolidPeso molecolare:614.72Sodium dichloroacetate
CAS:Sodium dichloroacetate (BCA) inhibits PDK (IC50: 183 μM PDK2, 80 μM PDK4), triggers cancer cell apoptosis, and impedes tumor growth.Formula:C2HCl2NaO2Purezza:99.32% - 99.87%Colore e forma:White PowderPeso molecolare:150.92A939572
CAS:A939572 is stearoyl-CoA desaturase1 (SCD1) inhibitor with IC50 values of <4 nM for mSCD1 and 37 nM for hSCD1.Formula:C20H22ClN3O3Purezza:99.96% - ≥95%Colore e forma:SolidPeso molecolare:387.86Ref: TM-T4515
1mg35,00€5mg78,00€10mg115,00€25mg225,00€50mg360,00€100mg567,00€200mg820,00€1mL*10mM (DMSO)81,00€Enasidenib
CAS:Enasidenib (AG-221) is an orally available inhibitor of specific mutant forms of the mitochondrial enzyme isocitrate dehydrogenase type 2 (IDH2), with potentialFormula:C19H17F6N7OPurezza:98% - >99.99%Colore e forma:SolidPeso molecolare:473.38Ref: TM-T2346
5mg47,00€10mg70,00€25mg93,00€50mg111,00€100mg144,00€200mg207,00€500mg350,00€1mL*10mM (DMSO)50,00€3-Hydroxybenzaldehyde
CAS:3-Hydroxybenzaldehyde is a compound useful in organic synthesis.Formula:C7H6O2Purezza:99.60%Colore e forma:DrypowderPeso molecolare:122.12R162
CAS:R162 is an effective glutamate dehydrogenase 1 (GDH1) inhibitor.Formula:C17H12O3Purezza:96.21% - 98.15%Colore e forma:SolidPeso molecolare:264.28Ivosidenib
CAS:Ivosidenib (AG-120) is an oral IDH1 inhibitor targeting mutated IDH1 to reduce 2-hydroxyglutarate and hinder tumor growth.Formula:C28H22ClF3N6O3Purezza:98.71% - 99.98%Colore e forma:SolidPeso molecolare:582.96AGI-5198
CAS:AGI-5198 (IDH-C35) is a highly effective and specific inhibitor of IDH1 R132H/R132C mutants (IC50: 0.07/0.16 μM).Formula:C27H31FN4O2Purezza:97.37% - 99.23%Colore e forma:SolidPeso molecolare:462.56(R)-GNE-140
CAS:(R)-GNE-140 (GNE-140) is an effective LDHA/LDHB inhibitor (IC50s: 3/5 nM) and is 18-fold more potent than S enantiomer.Formula:C25H23ClN2O3S2Purezza:98.25% - 98.91%Colore e forma:SolidPeso molecolare:499.04Nitrofen
CAS:Nitrofen is a selective contact herbicide. Nitrofen is a protoporphyrinogen oxidase and retinal dehydrogenase inhibitor.Formula:C12H7Cl2NO3Purezza:99.92%Colore e forma:Less Crystals Or Black Solid Used As A Pre- Or Post-Emergence HerbicidePeso molecolare:284.09SW033291
CAS:SW033291 is a small-molecule inhibitor of 15-PGDH (Ki=0.1 nM) that increases prostaglandin PGE2 levels in bone marrow and other tissues.Formula:C21H20N2OS3Purezza:97.26% - 99.02%Colore e forma:SolidPeso molecolare:412.59Ref: TM-T2121
1mg40,00€2mg52,00€5mg87,00€10mg119,00€25mg210,00€50mg354,00€100mg512,00€1mL*10mM (DMSO)87,00€LDHA-IN-4
CAS:LDHA-IN-4 (AZ33) is an LDHA inhibitor. Binding affinity to 6-His-tagged human LDHA expressed in E.coli BL21 (DE3) by SPR analysis with an active value of 93 nM.Formula:C25H27N3O6SPurezza:98.17% - 99.68%Colore e forma:SolidPeso molecolare:497.566PGD-IN-S3
CAS:6PGD-IN-S3 (6PGD Inhibitor S3) is an inhibitor of 6-phosphogluconate dehydrogenase (6PGD).Formula:C15H10O4Purezza:99.12%Colore e forma:SolidPeso molecolare:254.24AZD7545
CAS:AZD7545 is a potent PDHK inhibitor.Formula:C19H18ClF3N2O5SPurezza:99.12% - 99.96%Colore e forma:SolidPeso molecolare:478.87BVT-14225
CAS:BVT-14225 is a selective 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor (IC50=52 nM).Formula:C16H20ClN3O3S2Purezza:97.78%Colore e forma:SolidPeso molecolare:401.93Ref: TM-T3542
1mg47,00€2mg59,00€5mg96,00€10mg142,00€25mg254,00€50mg411,00€100mg610,00€1mL*10mM (DMSO)105,00€Perfluorooctanoic acid
CAS:Perfluorooctanoic acid (PFOA) (PFOA) is a persistent and widespread industry-made chemical.Formula:C8HF15O2Purezza:99.70%Colore e forma:White To Off-White Powder OthersolidPeso molecolare:414.07Ref: TM-T9333
5mg55,00€10mg82,00€25mg126,00€50mg182,00€100mg273,00€200mg409,00€500mg677,00€1mL*10mM (DMSO)81,00€PHGDH-inactive
CAS:PHGDH inactive is inactive against PHGDH and serves as a negative control for NCT-502 and NCT-503 [1].Formula:C17H21N5SPurezza:99.83%Colore e forma:SolidPeso molecolare:327.45Ref: TM-T23150
5mg38,00€10mg60,00€25mg117,00€50mg182,00€100mg261,00€200mg366,00€1mL*10mM (DMSO)47,00€MK-8245
CAS:MK-8245 is a liver-targeting SCD inhibitor for human SCD1 (IC50: 1 nM) and for rat/mouse SCD1 (IC50: 3 nM), with anti-diabetic and anti-dyslipidemic function.Formula:C17H16BrFN6O4Purezza:97.58% - 99%Colore e forma:SolidPeso molecolare:467.25Ref: TM-T2650
1mg39,00€5mg96,00€10mg153,00€25mg273,00€50mg465,00€100mg648,00€200mg900,00€1mL*10mM (DMSO)97,00€NCT-501
CAS:NCT-501 is a potent and selective inhibitor of Aldehyde Dehydrogenase 1A1 (ALDH1A1) with IC50 of 40 nM.Formula:C21H32N6O3Purezza:99.19%Colore e forma:SolidPeso molecolare:416.52G6PDi-1
CAS:G6PDi-1 is an effective G6PD inhibitor. It depletes NADPH and decreases inflammatory cytokine production.Formula:C14H12N4OSPurezza:98.69%Colore e forma:SolidPeso molecolare:284.34BMS-823778 hydrochloride
CAS:<p>BMS-823778 hydrochloride is a potent, selective, and orally active inhibitor of 11β-HSD1 (11β-Hydroxysteroid Dehydrogenase Type 1), demonstrating an IC50 (half</p>Formula:C18H19Cl2N3OColore e forma:SolidPeso molecolare:364.27Galloflavin
CAS:Galloflavin is a lactate dehydrogenase inhibitor. Galloflavin inhibits both human LDH isoforms (type A and type B).Cost-effective and quality-assured.Formula:C12H6O8Purezza:96.24% - 97.47%Colore e forma:SolidPeso molecolare:278.17BVT 2733
CAS:<p>BVT 2733 is a new, non-steroidal, isoform-specific inhibitor of 11β-HSD1.</p>Formula:C17H21ClN4O3S2Purezza:98% - 99.64%Colore e forma:SolidPeso molecolare:428.96NCT-505
CAS:NCT-505 is a potent and selective inhibitor of aldehyde dehydrogenase (ALDH1A1, IC50 = 7 nM) and a weak inhibitor of hALDH1A2, hALDH1A3, hALDH2, hALDH3A1 withFormula:C27H28FN5O3SPurezza:99.93%Colore e forma:SolidPeso molecolare:521.61Ref: TM-T12196
1mg115,00€5mg235,00€10mg353,00€25mg562,00€50mg758,00€100mg1.017,00€200mg1.359,00€1mL*10mM (DMSO)270,00€PfDHODH-IN-1
CAS:PfDHODH-IN-1 is an inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase(PfDHODH) which catalyzes the rate-limiting step for DNA and RNA biosynthesis.Formula:C14H11F3N2O2Purezza:99.87%Colore e forma:SolidPeso molecolare:296.24Ref: TM-T12438
1mg50,00€5mg106,00€10mg160,00€25mg311,00€50mg472,00€100mg695,00€200mg938,00€1mL*10mM (DMSO)97,00€CM10
CAS:CM10 is an aldehyde dehydrogenase 1A family(ALDH1A) inhibitor.Formula:C20H23N3OPurezza:99.84%Colore e forma:SolidPeso molecolare:321.42Dihydrouracil
CAS:5,6-Dihydrouracil (5,6-Dihydrouracil) is an intermediate breakdown product of uracil.Formula:C4H6N2O2Purezza:99.75%Colore e forma:SolidPeso molecolare:114.1NCT-501 hydrochloride
CAS:NCT-501 hydrochloride: potent, selective ALDH1A1 inhibitor based on theophylline; IC50 of 40 nM; highly discriminant against other ALDHs.Formula:C21H33ClN6O3Colore e forma:SolidPeso molecolare:452.98BI-187004
CAS:BI-187004 is an 11β-hydroxysteroid dehydrogenase 1 inhibitor.Formula:C21H18N4OPurezza:98.63%Colore e forma:SolidPeso molecolare:342.39L-Allylglycine
CAS:L-Allylglycine is a potent inhibitor of the synthetic enzyme for GABA, glutamic acid decarboxylase.Formula:C5H9NO2Purezza:≥98%Colore e forma:White To Off-White Crystalline PowderPeso molecolare:115.13AKR1C3-IN-4
CAS:AKR1C3-IN-4: potent, selective AKR1C3 inhibitor, IC50 = 0.56 μM, potential for CRPC research.Formula:C14H10F3NO2Purezza:98.59%Colore e forma:SolidPeso molecolare:281.23Vidofludimus
CAS:Vidofludimus (SC12267) (4SC-101, SC12267) is a novel small molecule inhibitor of dihydroorotate dehydrogenase (DHODH).Formula:C20H18FNO4Purezza:98.33% - 99.58%Colore e forma:SolidPeso molecolare:355.36VER-246608
CAS:VER-246608 inhibits PDK (IC50: 35-91 nM), boosts PDC, reduces glycolysis, causes cancer cell cytostasis, and enhances doxorubicin effects.Formula:C28H23ClF2N4O4Purezza:98.5%Colore e forma:SolidPeso molecolare:552.96Ref: TM-T17224
1mg52,00€2mg74,00€5mg111,00€10mg170,00€25mg329,00€50mg502,00€100mg730,00€1mL*10mM (DMSO)137,00€AKR1C3-IN-1
CAS:AKR1C3-IN-1 is a potent and selective inhibitor of AKR1C3(IC50 of 13 nM).Formula:C16H15NO4SPurezza:98.02%Colore e forma:SolidPeso molecolare:317.36NCT-503
CAS:<p>NCT-503 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor with no activity against other dehydrogenases. NCT-503 has antitumor activity. Cost-effective and quality-assured.</p>Formula:C20H23F3N4SPurezza:98.91% - 99.84%Colore e forma:SolidPeso molecolare:408.48Tiazofurin
CAS:Tiazofurin, a synthetic nucleoside, has anti-cancer effects and inhibits IMPDH as TAD after metabolism.Formula:C9H12N2O5SPurezza:99.91%Colore e forma:SolidPeso molecolare:260.27Mutant IDH1-IN-1
CAS:Mutant IDH1-IN-1 is a potent mutant IDH1 R132 h inhibitor with IC50 < 0.1 uM.Formula:C30H31FN4O2Purezza:99.49% - >99.99%Colore e forma:SolidPeso molecolare:498.59Ref: TM-T2043
2mg47,00€5mg71,00€10mg99,00€25mg183,00€50mg263,00€100mg383,00€200mg517,00€1mL*10mM (DMSO)74,00€Nitrofurazone
CAS:Nitrofurazone (Furacilin) is a topical anti-infective agent effective against gram-negative and gram-positive bacteria.Formula:C6H6N4O4Purezza:99.87%Colore e forma:Pale Yellow Needles Solution) 6 0 - 6 5 Alkaline Solutions Are Dark Orange (Ntp 1992)Peso molecolare:198.14AG-120 (racemic)
CAS:AG-120 (racemic) is an oral IDH1 inhibitor with potential anti-cancer effects.Formula:C28H22ClF3N6O3Purezza:99.56%Colore e forma:SolidPeso molecolare:582.96Vidofludimus hemicalcium
CAS:Vidofludimus hemicalcium: oral DHODH inhibitor, FXR modulator, for autoimmune and fatty liver research.Formula:C20H18FNO4CaColore e forma:SolidPeso molecolare:375.4Imidazole-5-propionic acid
CAS:<p>Imidazole-5-propionic acid (Imidazolylpropionic acid) is a product of histidine metabolism and may involve oxidation or transamination.</p>Formula:C6H8N2O2Purezza:99.62%Colore e forma:SolidPeso molecolare:140.14PfDHODH-IN-2
CAS:PfDHODH-IN-2: powerful antimalarial, blocks PfDHODH (IC50: 1.11 μM), for malaria research.Formula:C13H12ClNO3SPurezza:98.9%Colore e forma:SolidPeso molecolare:297.76Ref: TM-T8767
1mg48,00€5mg97,00€10mg145,00€25mg259,00€50mg383,00€100mg545,00€200mg740,00€1mL*10mM (DMSO)105,00€AGI-6780
CAS:AGI-6780 is a potent and selective inhibitor of IDH2 R140Q mutant.Formula:C21H18F3N3O3S2Purezza:98.19% - 99.7%Colore e forma:SolidPeso molecolare:481.51Ref: TM-T1809
1mg37,00€2mg52,00€5mg79,00€10mg119,00€25mg220,00€50mg393,00€100mg587,00€500mg1.264,00€1mL*10mM (DMSO)85,00€Fomepizole
CAS:Fomepizole (4-Methylpyrazole), a competitive inhibitor of alcohol dehydrogenase, is used as an antidote in methanol or ethylene glycol poisoning.Formula:C4H6N2Purezza:98.1% - 99.94%Colore e forma:Yellow <13°C Solid >13°C LiquidPeso molecolare:82.1Brequinar
CAS:Brequinar (NSC-368390) is a potent inhibitor of dihydroorotate dehydrogenase, with potent activities against a broad spectrum of viruses.Formula:C23H15F2NO2Purezza:99.1% - 99.57%Colore e forma:SolidPeso molecolare:375.37AG-636
CAS:AG-636 is a potent, reversible, selective and orally active DHODH inhibitor(IC50 of 17 nM). It has strong anticancer effects.Formula:C21H17N3O2Purezza:99.19%Colore e forma:SolidPeso molecolare:343.38Brequinar sodium
CAS:Bipenquinate is a potent and selective inhibitor of dihydroorotate dehydrogenase (DHODH) with IC50 of 20 nM, blocking de novo pyrimidine biosynthesis.Formula:C23H14F2NNaO2Purezza:98.16%Colore e forma:SolidPeso molecolare:397.36Ref: TM-T8332
2mg39,00€5mg66,00€10mg97,00€25mg172,00€50mg225,00€100mg314,00€200mg444,00€1mL*10mM (DMSO)78,00€WIN 18446
CAS:inhibitor of aldehyde dehydrogenase 1a2 (ALDH1a2)Formula:C12H20Cl4N2O2Purezza:99.69%Colore e forma:SolidPeso molecolare:366.11DS-1001b
CAS:DS-1001b is an inhibitor of mutant IDH-1 (Isocitrate Dehydrogenase-1)Formula:C29H29Cl3FN3O4Purezza:99.81%Colore e forma:SolidPeso molecolare:608.92Ref: TM-T7741
1mg37,00€5mg79,00€10mg119,00€25mg187,00€50mg283,00€100mg439,00€200mg635,00€1mL*10mM (DMSO)97,00€BAY-1436032
CAS:BAY-1436032 is a novel, selective and orally available inhibitor of pan-mutant isocitrate dehydrogenase 1 (IDH1).Formula:C26H30F3N3O3Purezza:99.65% - 99.71%Colore e forma:SolidPeso molecolare:489.53Ref: TM-TQ0042
1mg37,00€5mg79,00€10mg119,00€25mgPrezzo su richiesta50mgPrezzo su richiesta1mL*10mM (DMSO)85,00€DS44960156
CAS:DS44960156 is an inhibitor of methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) that inhibits both MTHFD2 and MTHFD1 and can be used in cancer research.Formula:C20H15NO5Purezza:99.13%Colore e forma:SolidPeso molecolare:349.34Ref: TM-T37655
1mg78,00€5mg169,00€10mg250,00€25mg432,00€50mg628,00€100mg905,00€1mL*10mM (DMSO)178,00€Enasidenib mesylate
CAS:Enasidenib mesylate (AG-221 mesylate) is a IDH2 inhibitor that promotes differentiation of leukemia myeloid cells for the treatment of acute myeloid leukemia.Formula:C20H21F6N7O4SPurezza:99.85%Colore e forma:SolidPeso molecolare:569.48GSK1940029
CAS:GSK1940029 (SCD inhibitor 1) is a stearoyl-coa desaturase (SCD) inhibitor.Formula:C18H16Cl2N4O2Purezza:99.48% - 99.49%Colore e forma:SolidPeso molecolare:391.25Nedosiran
CAS:Nedosiran, a GalNAc-dsRNA conjugate for RNAi, targets LDH to treat primary hyperoxaluria and ESRD.Colore e forma:SolidRef: TM-T39802
1mgPrezzo su richiesta5mgPrezzo su richiesta10mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaTriflupromazine
CAS:Triflupromazine is a dopamine receptor D1/D2 antagonist and LHDA inhibitor that suppresses dopamine activity in (CNS)mental disorders, sedation, and antiemesis.Formula:C18H19F3N2SColore e forma:SolidPeso molecolare:352.42Nitrophenide
CAS:Nitrophenide, a 3,3'-Dinitrodiphenyl disulfide, blocks M1PDH in the mannitol cycle, serving as an anticoccidial.Formula:C12H8N2O4S2Purezza:99.78%Colore e forma:SolidPeso molecolare:308.33hDHODH-IN-2
CAS:hDHODH-IN-2: Leflunomide metabolite analog, inhibits human dihydroorotate dehydrogenase, anti-inflammatory.Formula:C19H16N2O2Purezza:98%Colore e forma:SolidPeso molecolare:304.349SCH-451659
CAS:SCH-451659 is an 17β-hydroxysteroid dehydrogenases (17β-HSDs) inhibitor.Formula:C30H39Cl2N3O2Purezza:98%Colore e forma:SolidPeso molecolare:544.56673-A
CAS:673-A inhibits ALDH1A, depletes ovarian CSCs, induces necroptosis, and reverses chemo resistance.Formula:C15H13NOColore e forma:SolidPeso molecolare:223.27DHODH-IN-12
CAS:DHODH-IN-12 is a leflunomide derivative and a weak dihydrorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.07.Formula:C10H9N3O2Purezza:99.53%Colore e forma:SolidPeso molecolare:203.2Ref: TM-T11021
1mg77,00€5mg158,00€10mg225,00€25mg338,00€50mg472,00€100mg645,00€200mg869,00€1mL*10mM (DMSO)129,00€CM39
CAS:CM39 inhibits ALDH, linked to cancer stem-like cells & chemoresistance.Formula:C19H15FN4OSColore e forma:SolidPeso molecolare:366.41Nitrefazole
CAS:Nitrefazole: a 4-nitroimidazole, inhibits ALDH enzyme crucial for alcohol metabolism, has potent, durable effects.Formula:C10H8N4O4Colore e forma:SolidPeso molecolare:248.1911β-HSD1-IN-6
CAS:11β-HSD1-IN-6 is a potent inhibitor of 11β hydroxysteroid dehydrogenase enzymes (11β-HSDs).Formula:C21H19ClN4OColore e forma:SolidPeso molecolare:378.86MEDS433
CAS:MEDS433 inhibits dihydroorotate dehydrogenase (IC50 1.2 nM) and blocks replication of hCoV-OC43, hCoV-229E, SARS-CoV-2 at nanomolar levels.Formula:C20H11F4N3O2Colore e forma:SolidPeso molecolare:401.31hDHODH-IN-11
CAS:hDHODH-IN-11: potent hDHODH inhibitor, IC50 7.2 nM, low cytotoxicity, for AML research.Formula:C24H23N3O3Colore e forma:SolidPeso molecolare:401.46RS6212
CAS:<p>RS6212 is a specific lactate dehydrogenase (LDH) inhibitor (IC50=12.03 μ M）。 RS6212 shows strong anticancer activity in a variety of cancer cell lines.</p>Formula:C20H22N4O3SColore e forma:SolidPeso molecolare:398.48AMG-221
CAS:AMG-221: potent 11β-HSD1 inhibitor, lowers glucose & insulin, reduces obesity in mice.Formula:C14H22N2OSPurezza:98%Colore e forma:SolidPeso molecolare:266.411β-HSD1-IN-10
CAS:11β-HSD1-IN-10, a potent inhibitor of 11β-HSD1 with an IC50 value of 1.8 µM for humans, is suitable for research into obesity, hyperglycemia, and cognitiveFormula:C16H10F3NO2Colore e forma:SolidPeso molecolare:305.25RORγt/DHODH-IN-2
CAS:RORγt/DHODH-IN-2 (compound 1) is a potent dual RORγt/DHODH inhibitor that can be used in the study of inflammatory bowel disease (IBD).Formula:C25H30N4OSColore e forma:SolidPeso molecolare:434.6DHODH-IN-19
CAS:DHODH-IN-19, a strong DHODH blocker, may help treat cancer and inflammation. (Patent WO2021238881A1)Formula:C22H18ClF6N3O3Colore e forma:SolidPeso molecolare:521.84ASP3662
CAS:ASP3662/SPI-62: Potent, selective CNS-penetrable 11β-HSD1 inhibitor; potential neuropathic pain treatment.Formula:C19H16ClF3N4O2Colore e forma:SolidPeso molecolare:424.8TM-1
CAS:TM-1: PDHK inhibitor, IC50 - PDHK1: 2.97μM, PDHK2: 5.2μM, prevents PDHC phosphorylation, inhibits cancer cell growth.Formula:C26H32N2O6Colore e forma:SolidPeso molecolare:468.54DHODH-IN-3
CAS:DHODH-IN-3: Human DHODH inhibitor with IC50 of 261 nM, Kiapp 32 nM, potential anti-malaria drug.Formula:C17H13ClN2O2Purezza:98%Colore e forma:SolidPeso molecolare:312.75ALDH3A1-IN-2
CAS:ALDH3A1-IN-2 is a potent inhibitor targeting ALDH3A1 (IC50=1.29µM), potentially useful in cancer research.Formula:C11H14N2O3Colore e forma:SolidPeso molecolare:222.2411β-HSD1-IN-9
CAS:<p>11β-HSD1-IN-9 is a potent inhibitor of 11β-HSD1, displaying IC50 values of 0.48 µM for human and 1.3 µM for murine variants, respectively.</p>Formula:C13H9F3N2OColore e forma:SolidPeso molecolare:266.22DHODH-IN-21
CAS:DHODH-IN-21, orally active DHODH blocker with 1.1 nM IC50, shows anticancer activity, potential for AML research.Formula:C20H19ClF4N6O4Colore e forma:SolidPeso molecolare:518.85P1788
CAS:P1788 is a dihydroorotate dehydrogenase (DHODH) inhibitor that can induce DNA damage [1].Formula:C15H17NO3Colore e forma:SolidPeso molecolare:259.3Epostane
CAS:Epostane is a 3β-hydroxysteroid dehydrogenase inhibitor that blocks the biosynthesis of progesterone and pregnenolone.Cost-effective and quality-assured.Formula:C22H31NO3Purezza:>99.99%Colore e forma:SolidPeso molecolare:357.49DHODH-IN-20
CAS:Dhodh-in-20 (Compound 133), a potent DHODH inhibitor, may help study acute myeloid leukemia and inhibit tumor growth.Formula:C24H25F4N3O3Colore e forma:SolidPeso molecolare:479.47ALDH1A1-IN-3
CAS:ALDH1A1-IN-3 selectively inhibits ALDH1A1, enhances HepG2 glucose consumption for metabolic research.Formula:C31H36F3N5O4Colore e forma:SolidPeso molecolare:599.64DHODH-IN-24
CAS:DHODH-IN-24 (compound 16) serves as a powerful inhibitor of human dihydroorotate dehydrogenase (DHODH), exhibiting an IC50 value of 91 nM [1].Formula:C26H26N4Colore e forma:SolidPeso molecolare:394.51BI-4924
CAS:BI-4924 is a PHGDH inhibitor that disrupts serine biosynthesis by intracellular trapping and can be used to study metabolic disorders.Formula:C21H20Cl2N2O6SPurezza:99.55%Colore e forma:SolidPeso molecolare:499.36KM04416
CAS:KM04416 is a GPD2 inhibitor that inhibits LUAD progression by modulating immune cell infiltration.Formula:C12H11NO3SPurezza:99.88%Colore e forma:SolidPeso molecolare:249.29BI-135585
CAS:BI-135585 is an orally active, selective and potent inhibitor of human 11β-hydroxysteroid dehydrogenase-1 (HSD1) for the study of type 2 diabetes.Formula:C28H32N2O4Purezza:99.45% - 99.57%Colore e forma:SolidPeso molecolare:460.57hDHODH-IN-9
CAS:hDHODH-IN-9 is a potent hDHODH inhibitor, IC50=0.34 μM, toxic to MCF-7/A375 cells, promising for cancer research.Formula:C21H21NO4Colore e forma:SolidPeso molecolare:351.4CM026
CAS:CM026 inhibits ALDH1A1 selectively, binds to its aldehyde pocket uncompetitively.Formula:C22H30N6O4Colore e forma:SolidPeso molecolare:442.51ML387
CAS:ML387 is an inhibitor of human NAD(+)- dependent 15- hydroxyprostaglandin dehydrogenase.Formula:C20H21N3O2Purezza:98%Colore e forma:SolidPeso molecolare:335.4Oxycinchophen
CAS:Oxycinchophen: Quinoline-based anti-rheumatic with P-selectin inhibition, DHOD blockade, and anti-inflammatory impacts on vascular muscle.Formula:C16H11NO3Purezza:98%Colore e forma:SolidPeso molecolare:265.26GW648495
CAS:GW648495 is a PfDHODH inhibitor that shows greater than 4,000-fold selectivity for the malarial enzyme.Formula:C16H13N5Purezza:98%Colore e forma:SolidPeso molecolare:275.31BVT-116429
CAS:BVT-116429 is an inhibitor of 11β-HSD1.Formula:C13H12F4N2OSPurezza:98%Colore e forma:SolidPeso molecolare:320.31Genz-669178
CAS:Genz-669178 is a wild-type inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH).Formula:C17H14N4OSPurezza:98%Colore e forma:SolidPeso molecolare:322.38GA11
CAS:<p>GA11is an inhibitor of ALDH1. It also displays anti-GBM effects in vitro and in vivo.</p>Formula:C19H14N2Purezza:98%Colore e forma:SolidPeso molecolare:270.33EN40
CAS:EN40, as a covalent ligand, is a selective inhibitor of aldehyde dehydrogenase 3A1 (IC50: 2 uM).Formula:C13H15NO2Colore e forma:SolidPeso molecolare:217.26p-Valerylphenol
CAS:p-Valerylphenol (NSC-49186) can be used to synthesize acylphenoxyacetic acid compounds.Formula:C11H14O2Purezza:99.87%Colore e forma:White To Light Beige PowderPeso molecolare:178.23UCK2 Inhibitor-2
CAS:UCK2 Inhibitor-2 is a non-competitive inhibitor of uridine-cytidine kinase 2 (UCK2) with IC50=3.8 µM that inhibits UCK2-mediated nucleoside recycling in cells.Formula:C28H23N3O4SPurezza:98.76% - 99.25%Colore e forma:SolidPeso molecolare:497.57M77976
CAS:M77976 inhibits PDK4 with an IC50 of 648 μM, targeting obesity and diabetes research.Formula:C17H16N2O3Purezza:99.92%Colore e forma:SolidPeso molecolare:296.32Chlorisondamine diiodide
CAS:Chlorisondamine diiodide is a selective nAChR antagonist and ganglionic blocker that persistently antagonizes partial central effects of nicotine.Formula:C14H20Cl4I2N2Purezza:99.97%Colore e forma:SolidPeso molecolare:611.94INCB13739
CAS:INCB13739 is an 11β-HSD1 inhibitor that can be used in the study of hyperlipidemia and hypertriglyceridemia.Formula:C28H25N3O4Purezza:99.32%Colore e forma:SoildPeso molecolare:467.52Ref: TM-T60203
1mg99,00€5mg226,00€10mg364,00€25mg722,00€50mg998,00€100mg1.320,00€200mg1.795,00€1mL*10mM (DMSO)240,00€IMB-XMA0038
CAS:IMB-XMA0038 is a Mycobacterium tuberculosis aspartate semialdehyde dehydrogenase inhibitor with antimicrobial activity for use in tuberculosis research.Formula:C11H10N4O6Purezza:98.94% - 99.96%Colore e forma:SolidPeso molecolare:294.22MDH1-IN-2
CAS:MDH1-IN-2 is a potent MDH1 inhibitor with potential anticancer activity for the study of diseases related to the immune system.Formula:C25H33NO5Purezza:99.21%Colore e forma:SolidPeso molecolare:427.5311β-HSD1-IN-12
CAS:11β-HSD1-IN-12 is an 11β-HSD1 inhibitor.11β-HSD1-IN-12 is implicated in the conversion of glucocorticoids in vivo and can be used to study metabolic syndromeFormula:C19H27ClN2O3SPurezza:99.89%Colore e forma:SolidPeso molecolare:398.95S07-2005 (racemic)
CAS:S07-2005 is a selective AKR1C3 inhibitor with IC50 of 0.13 μM, potential in enhancing cancer chemotherapy.Formula:C20H23NO6Colore e forma:SolidPeso molecolare:373.4AGI-14100
CAS:<p>AGI-14100 is a novel and orally available mIDH1 inhibitor.AGI-14100 is used for the treatment of primary human myeloid leukemia.</p>Formula:C29H22ClF4N5O3Purezza:99.91%Colore e forma:SolidPeso molecolare:599.96RV01
CAS:RV01, a resveratrol-like quinoline, inhibits DNA damage, ALDH2 expression, and has antioxidant and anti-inflammatory properties.Formula:C17H13NO2Purezza:99.93%Colore e forma:SolidPeso molecolare:263.29Ref: TM-T12781
1mg62,00€5mg135,00€10mg207,00€25mg353,00€50mg509,00€100mg672,00€200mg910,00€1mL*10mM (DMSO)149,00€hDHODH-IN-3
CAS:hDHODH-IN-3 is an inhibitor of human dihydroorotate dehydrogenase with a pMIC50 value of 8.6. hDHODH-IN-3 can inhibit measles virus replication.Formula:C18H19BrN4O2Purezza:99.871%Colore e forma:SolidPeso molecolare:403.27Ref: TM-T11025
1mg64,00€2mg93,00€5mg140,00€10mg215,00€25mg354,00€50mg500,00€100mg658,00€500mgPrezzo su richiesta1mL*10mM (DMSO)150,00€Laflunimus
CAS:Laflunimus (HR325) is a DHODH inhibitor that inhibits immunoglobulin secretion in vitro and in vivo,by interfering with pyrimidine metabolism,neuralgia.Formula:C15H13F3N2O2Purezza:99.86%Colore e forma:SolidPeso molecolare:310.27
