Deidrogenasi
Le deidrogenasi sono enzimi coinvolti nelle reazioni di ossidoriduzione delle vie metaboliche, svolgendo un ruolo centrale nella produzione di energia e nella respirazione cellulare. Questi enzimi sono cruciali per processi come il ciclo dell'acido citrico, la glicolisi e l'ossidazione degli acidi grassi. Gli inibitori delle deidrogenasi sono strumenti importanti nello studio delle malattie metaboliche, del cancro e dello stress ossidativo. Presso CymitQuimica, offriamo una selezione completa di inibitori delle deidrogenasi per supportare la tua ricerca in metabolismo, biologia del cancro e biochimica.
Trovati 322 prodotti per "Deidrogenasi".
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MF-438
CAS:MF-438 is an effective and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor (EC50: 2.3 nM for rSCD1).Formula:C19H18F3N5OSPurezza:98.98% - 99.50%Colore e forma:SolidPeso molecolare:421.439CBR-5884
CAS:CBR-5884: active PHGDH inhibitor, IC50=33μM, disrupts serine synthesis, selectively targets high-serine cancers.Formula:C14H12N2O4S2Purezza:99.97%Colore e forma:SolidPeso molecolare:336.38618β-Glycyrrhetyl-3-O-sulfate
CAS:18β-Glycyrrhetyl-3-O-sulfate (Glycyrrhetic acid 3-O-(hydrogen sulfate)), a major metabolite of Glycyrrhetinic acid (GA), serves as a potent inhibitor of type 2Formula:C30H46O7SColore e forma:SolidPeso molecolare:550.75PHGDH-IN-5
CAS:Compound B12 (PHGDH-IN-5) acts as a covalent inhibitor of PHGDH, demonstrating an IC50 value of 0.29 μM. It has been shown to inhibit the proliferation of cancer cell lines that overexpress PHGDH and reduce the production of glucose-derived serine in MDA-MB-468 cells [1].Formula:C8H5NO4SColore e forma:SolidPeso molecolare:211.20DHODH-IN-18
CAS:DHODH-IN-18 is a human DHODH inhibitor ( IC 50 = 0.2 nM).Formula:C21H16ClF5N6O4Colore e forma:SolidPeso molecolare:546.84SCD1 inhibitor-3
CAS:SCD1 inhibitor-3 (ML-270) is a highly effective and orally available compound that inhibits SCD1 with remarkable safety.Formula:C19H16FN7O2Purezza:99.5%Colore e forma:SolidPeso molecolare:393.3744LDH-IN-3
LDH-IN-3 (compound E38) is an inhibitor of lactate dehydrogenase (LDH) and a potential protective agent against ischemic neuronal damage in the eyes and brain. It functions through the HO-1/SIRT1 pathway.Formula:C32H27NO5Colore e forma:SolidPeso molecolare:505.56hDHODH-IN-12
hDHODH-IN-12 is a potent inhibitor of dihydroorotate dehydrogenase (DHODH), exhibiting an inhibitory concentration (IC50) of 0.421 μM.Formula:C22H15F3N4O3Purezza:98%Colore e forma:SolidPeso molecolare:440.3711β-HSD1-IN-11
CAS:11β-HSd1-in-11 is a potent and competitive inhibitor of 11-β-hydroxysteroid dehydrogenase 1 (11β-HSD1) IN rats and humans with IC50 values of 0.34 μM and 0.13Formula:C15H11F3O3SPurezza:99.61%Colore e forma:SolidPeso molecolare:328.306PDK-IN-2
PDK-IN-2 (Compound 1F), with an IC50 of 68 nM, is a potent PDK inhibitor that downregulates the expression of PDK1 and PDK4 in cells.Formula:C17H23AsCl2N2O2S2Colore e forma:SolidPeso molecolare:497.33MTHFD2-IN-3
MTHFD2-IN-3 (compound 10), a potent inhibitor of methylenetetrahydrofolate dehydrogenase (MTHFD2), demonstrates significant efficacy in obstructing the activityFormula:C22H19NO7SColore e forma:SolidPeso molecolare:441.45MTHFD2-IN-1
MTHFD2-IN-1 (compound 12) is a potent inhibitor of methylenetetrahydrofolate dehydrogenase (MTHFD2) [1].Formula:C24H21NO6Colore e forma:SolidPeso molecolare:419.43MTHFD2-IN-4 sodium
MTHFD2-IN-4 sodium, a potent inhibitor of MTHFD2 and a tricyclic coumarin derivative, is applicable in cancer research [1].Formula:C26H21F6N2NaO5Colore e forma:SolidPeso molecolare:578.44Succinate dehydrogenase-IN-4
Succinate dehydrogenase-IN-4 (Compound 4b) is an inhibitor of succinate dehydrogenase with an IC50 value of 3.38 μM. It exhibits antifungal activity against Physalospora piricola and Colletotrichum orbiculare, with EC50 values of 16.33 μM and 18.06 μM, respectively.Formula:C20H21N3O2S2Colore e forma:SolidPeso molecolare:399.531H-Tetrazole
CAS:1H-Tetrazole is a tetrazole heterocycle, a carboxyl bioisostere that inhibits 11β-HSD1 and mitochondrial function.Formula:CH2N4Peso molecolare:70.05LDHA-IN-10
LDHA-IN-10 (Compound HP19) is an inhibitor of lactate dehydrogenase A (LDHA) with an IC50 value of 5.2 μM. It reduces lactate production and ATP levels, inhibiting the proliferation of the pancreatic cancer cell line PANC-1. Additionally, LDHA-IN-10 induces G1/S cell cycle arrest and promotes apoptosis, showing potential for research in pancreatic ductal adenocarcinoma (PDAC).ALDH1A1-IN-5
ALDH1A1-IN-5 (compound 25) is a potent inhibitor of aldehyde dehydrogenase 1A1 (ALDH1A1), exhibiting EC50 values of 83 µM, 45 µM, and 43 µM for ALDH1A1, ALDH1A2, and ALDH1A3, respectively. This compound holds potential for research in high-grade serous ovarian cancer (HGSOC).Formula:C18H17Cl2N3O2Peso molecolare:377.06978DHODH-IN-23
CAS:DHODH-IN-23 is a DHODH inhibitor with oral activity. DHODH-IN-23 is often used in cancer research.Formula:C24H21ClFNO4Purezza:99.7%Colore e forma:SolidPeso molecolare:441.879LDHA-IN-3
CAS:LDHA-IN-3 is a potent selenobenzene-based LDHA inhibitor with a 145.2 nM IC50, useful in cancer research.Formula:C13H9F3SePurezza:99.71%Colore e forma:SolidPeso molecolare:301.17BMS-770767
CAS:BMS-770767 is a novel 11-betahydroxysteroid dehydrogenase type I (11ß-HSD1) inhibitor.Formula:C19H18ClN3O2Colore e forma:SolidPeso molecolare:355.82
