Deidrogenasi
Le deidrogenasi sono enzimi coinvolti nelle reazioni di ossidoriduzione delle vie metaboliche, svolgendo un ruolo centrale nella produzione di energia e nella respirazione cellulare. Questi enzimi sono cruciali per processi come il ciclo dell'acido citrico, la glicolisi e l'ossidazione degli acidi grassi. Gli inibitori delle deidrogenasi sono strumenti importanti nello studio delle malattie metaboliche, del cancro e dello stress ossidativo. Presso CymitQuimica, offriamo una selezione completa di inibitori delle deidrogenasi per supportare la tua ricerca in metabolismo, biologia del cancro e biochimica.
Trovati 301 prodotti di "Deidrogenasi"
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11β-HSD1-IN-10
CAS:11β-HSD1-IN-10, a potent inhibitor of 11β-HSD1 with an IC50 value of 1.8 µM for humans, is suitable for research into obesity, hyperglycemia, and cognitiveFormula:C16H10F3NO2Colore e forma:SolidPeso molecolare:305.25RORγt/DHODH-IN-2
CAS:<p>RORγt/DHODH-IN-2 (compound 1) is a potent dual RORγt/DHODH inhibitor that can be used in the study of inflammatory bowel disease (IBD).</p>Formula:C25H30N4OSColore e forma:SolidPeso molecolare:434.6DHODH-IN-19
CAS:DHODH-IN-19, a strong DHODH blocker, may help treat cancer and inflammation. (Patent WO2021238881A1)Formula:C22H18ClF6N3O3Colore e forma:SolidPeso molecolare:521.84ASP3662
CAS:ASP3662/SPI-62: Potent, selective CNS-penetrable 11β-HSD1 inhibitor; potential neuropathic pain treatment.Formula:C19H16ClF3N4O2Colore e forma:SolidPeso molecolare:424.8TM-1
CAS:TM-1: PDHK inhibitor, IC50 - PDHK1: 2.97μM, PDHK2: 5.2μM, prevents PDHC phosphorylation, inhibits cancer cell growth.Formula:C26H32N2O6Colore e forma:SolidPeso molecolare:468.54DHODH-IN-3
CAS:DHODH-IN-3: Human DHODH inhibitor with IC50 of 261 nM, Kiapp 32 nM, potential anti-malaria drug.Formula:C17H13ClN2O2Purezza:98%Colore e forma:SolidPeso molecolare:312.75ALDH3A1-IN-2
CAS:ALDH3A1-IN-2 is a potent inhibitor targeting ALDH3A1 (IC50=1.29µM), potentially useful in cancer research.Formula:C11H14N2O3Colore e forma:SolidPeso molecolare:222.2411β-HSD1-IN-9
CAS:<p>11β-HSD1-IN-9 is a potent inhibitor of 11β-HSD1, displaying IC50 values of 0.48 µM for human and 1.3 µM for murine variants, respectively.</p>Formula:C13H9F3N2OColore e forma:SolidPeso molecolare:266.22DHODH-IN-21
CAS:DHODH-IN-21, orally active DHODH blocker with 1.1 nM IC50, shows anticancer activity, potential for AML research.Formula:C20H19ClF4N6O4Colore e forma:SolidPeso molecolare:518.85P1788
CAS:P1788 is a dihydroorotate dehydrogenase (DHODH) inhibitor that can induce DNA damage [1].Formula:C15H17NO3Colore e forma:SolidPeso molecolare:259.3Epostane
CAS:Epostane is a 3β-hydroxysteroid dehydrogenase inhibitor that blocks the biosynthesis of progesterone and pregnenolone.Cost-effective and quality-assured.Formula:C22H31NO3Purezza:>99.99%Colore e forma:SolidPeso molecolare:357.49DHODH-IN-20
CAS:Dhodh-in-20 (Compound 133), a potent DHODH inhibitor, may help study acute myeloid leukemia and inhibit tumor growth.Formula:C24H25F4N3O3Colore e forma:SolidPeso molecolare:479.47ALDH1A1-IN-3
CAS:ALDH1A1-IN-3 selectively inhibits ALDH1A1, enhances HepG2 glucose consumption for metabolic research.Formula:C31H36F3N5O4Colore e forma:SolidPeso molecolare:599.64DHODH-IN-24
CAS:DHODH-IN-24 (compound 16) serves as a powerful inhibitor of human dihydroorotate dehydrogenase (DHODH), exhibiting an IC50 value of 91 nM [1].Formula:C26H26N4Colore e forma:SolidPeso molecolare:394.51BI-4924
CAS:BI-4924 is a PHGDH inhibitor that disrupts serine biosynthesis by intracellular trapping and can be used to study metabolic disorders.Formula:C21H20Cl2N2O6SPurezza:99.55%Colore e forma:SolidPeso molecolare:499.36KM04416
CAS:KM04416 is a GPD2 inhibitor that inhibits LUAD progression by modulating immune cell infiltration.Formula:C12H11NO3SPurezza:99.88%Colore e forma:SolidPeso molecolare:249.29BI-135585
CAS:BI-135585 is an orally active, selective and potent inhibitor of human 11β-hydroxysteroid dehydrogenase-1 (HSD1) for the study of type 2 diabetes.Formula:C28H32N2O4Purezza:99.45% - 99.57%Colore e forma:SolidPeso molecolare:460.57hDHODH-IN-9
CAS:hDHODH-IN-9 is a potent hDHODH inhibitor, IC50=0.34 μM, toxic to MCF-7/A375 cells, promising for cancer research.Formula:C21H21NO4Colore e forma:SolidPeso molecolare:351.4CM026
CAS:CM026 inhibits ALDH1A1 selectively, binds to its aldehyde pocket uncompetitively.Formula:C22H30N6O4Colore e forma:SolidPeso molecolare:442.51ML387
CAS:ML387 is an inhibitor of human NAD(+)- dependent 15- hydroxyprostaglandin dehydrogenase.Formula:C20H21N3O2Purezza:98%Colore e forma:SolidPeso molecolare:335.4
