Lipossigenasi
Le lipossigenasi sono una famiglia di enzimi che catalizzano l'ossigenazione degli acidi grassi polinsaturi, portando alla produzione di mediatori lipidici bioattivi come i leucotrieni e le lipossine. Questi mediatori svolgono ruoli critici nell'infiammazione, nelle risposte immunitarie e nel cancro. Gli inibitori della lipossigenasi sono utilizzati per studiare il loro ruolo nelle malattie infiammatorie, nell'asma e nel cancro. Presso CymitQuimica, offriamo una varietà di inibitori della lipossigenasi per supportare la tua ricerca in infiammazione, oncologia e metabolismo lipidico.
Trovati 125 prodotti di "Lipossigenasi"
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Zileuton
CAS:<p>Zileuton (A 64077) inhibits 5-lipoxygenase, reduces leukotrienes, aids bronchodilation, lessens mucus/edema, and helps manage asthma symptoms.</p>Formula:C11H12N2O2SPurezza:98.72% - 99.43%Colore e forma:Crystalline SolidPeso molecolare:236.29Diethylcarbamazine citrate
CAS:<p>Diethylcarbamazine citrate treats filariasis, targeting W. bancrofti and L. loa by inhibiting arachidonic acid in microfilaria.</p>Formula:C10H21N3O·C6H8O7Purezza:99.61%Colore e forma:White Crystalline Powder And Animals (Epa 1998)Peso molecolare:391.42Meclofenoxate hydrochloride
CAS:<p>Meclofenoxate HCl (Lucidril) boosts memory and cognition; it's a DIMETHYLAMINOETHANOL and p-chlorophenoxyacetic acid ester.</p>Formula:C12H16ClNO3·HClPurezza:97.05%Colore e forma:White Crystal PowderPeso molecolare:294.17Lagunamycin
CAS:<p>Lagunamycin is used as a novel 5-lipoxygenase inhibitor.</p>Formula:C19H21N3O4Colore e forma:SolidPeso molecolare:355.3913-epi-12-oxo Phytodienoic Acid
CAS:<p>13-epi-12-oxo PDA is a lipoxygenase derivative of α-linolenic acid in green plant leaves, often isomerizing during extraction and storage.</p>Formula:C18H28O3Colore e forma:SolidPeso molecolare:292.41(±)15-HEDE
CAS:<p>(±)15-HEDE is produced by non-enzymatic oxidation of 11,14-eicosadienoic acid.</p>Formula:C20H36O3Colore e forma:SolidPeso molecolare:324.5055-Lipoxygenase-IN-3
CAS:<p>Compound 14, a <1 μM 5-lipoxygenase inhibitor, researches inflammation, cancer, stroke, Alzheimer's.</p>Formula:C19H16ClN5OColore e forma:SolidPeso molecolare:365.82Damnacanthol
<p>Damnacanthol is a useful organic compound for research related to life sciences and the catalog number is T131609.</p>Formula:C16H12O5Colore e forma:SolidPeso molecolare:284.26715-LOX-1 inhibitor 1
CAS:<p>9c(i472) blocks 15-LO-1 (IC50=0.19μM), lowers NF-κB in RAW-Blue cells, & cuts Nos2/lipid peroxidation in RAW 264.7 at 0.2-5μM.</p>Formula:C22H21ClN2O4Colore e forma:SolidPeso molecolare:412.87DKI5
CAS:<p>DKI5, a LOX-1 inhibitor with 22.5 μM IC50, may exhibit anti-inflammatory, antioxidant, and anti-lipid peroxidation effects in vitro.</p>Formula:C8H10N4SPurezza:98%Colore e forma:SoildPeso molecolare:194.26(-)-Dihydroguaiaretic acid
<p>(-)-Dihydroguaiaretic acid is a useful organic compound for research related to life sciences and the catalog number is T126154.</p>Formula:C20H26O4Colore e forma:SolidPeso molecolare:330.424CMI977
CAS:<p>CMI977 is a potent inhibitor of 5-Lipoxygenase (5-LO).</p>Formula:C16H19FN2O4Purezza:98%Colore e forma:SolidPeso molecolare:322.33E 6080 HCl
CAS:<p>E 6080 HCl is a 5-lipoxygenase inhibitor and can be used to study bronchial diseases.</p>Formula:C17H20ClN3O3S2Purezza:99.80%Colore e forma:SoildPeso molecolare:413.945-LOX-IN-5
<p>Compound 29, also known as 5-LOX-IN-5, is a 5-lipoxygenase (5-LOX) inhibitor with an inhibitory concentration 50 (IC50) of 56 nM, utilized in research</p>Formula:C19H18BrN3O2SPurezza:98%Colore e forma:SolidPeso molecolare:432.33ZD-2138
CAS:<p>ZD-2138: Selective 5-LOX inhibitor, eases allergen-induced asthma attacks and airway constriction in guinea pigs.</p>Formula:C23H24FNO4Purezza:99.68% - >99.99%Colore e forma:SolidPeso molecolare:397.44CBS-1114 HCl
CAS:<p>CBS-1114 HCl: 5-lipoxygenase inhibitor, anti-inflammatory, improves heart function, reduces heart's fat.</p>Formula:C13H14ClN3Purezza:99.36%Colore e forma:SoildPeso molecolare:247.72h15-LOX-2 inhibitor 2
<p>Compound 10 (h15-LOX-2 inhibitor 2) suppresses h15-LOX activity, exhibiting IC 50 and K i values of 26.9 μM and 16.4 μM, respectively.</p>Formula:C22H30Cl2N6O3Colore e forma:SolidPeso molecolare:497.422-Methyl-1-naphthol
CAS:<p>2-Methyl-1-naphthol is a prostaglandin G/H synthase and polyunsaturated fatty acid 5-lipoxygenase inhibitor, suitable for biochemical experiments.</p>Formula:C11H10OPurezza:98.33%Colore e forma:SolidPeso molecolare:158.21-Naphthyl 3,5-dinitrobenzoate
CAS:<p>1-Naphthyl 3,5-dinitrobenzoate (JMC-4) is an inhibitor of 5-LOX can be used in studies about inflammatory therapy.</p>Formula:C17H10N2O6Purezza:99.79%Colore e forma:SolidPeso molecolare:338.27ThioLox
CAS:<p>ThioLox, a 15-LOX-1 inhibitor (IC50: 12 μM), has anti-inflammatory, neuroprotective benefits, and guards against glutamate toxicity.</p>Formula:C15H18N2OSPurezza:99.98%Colore e forma:SoildPeso molecolare:274.385-LOX/NO-IN-1
<p>5-LOX/NO-IN-1 (Compound 7e) is a dual inhibitor of 5-LOX and nitric oxide release. It exhibits an IC50 value of 2.833 μM for 5-LOX and demonstrates anti-inflammatory properties.</p>Formula:C22H18N6O4Colore e forma:SolidPeso molecolare:430.42mPGES-1/5-LOX-IN-1
<p>mPGES-1/5-LOX-IN-1 (compound 3j) is a potent, orally active dual inhibitor of mPGES-1 and 5-LOX, with IC50 values of 0.92 and 1.89 µM, respectively. Additionally, mPGES-1/5-LOX-IN-1 exhibits anti-inflammatory properties.</p>Formula:C20H22N4O6SPeso molecolare:446.12601Caffeoylcalleryanin
CAS:<p>Caffeoylcalleryanin demonstrated potent inhibitory activity against 15-lipoxygenase (15-LOX), with an IC50 value of 1.59 μM. Furthermore, ethanol extract from A. pulchra leaves (EEAPL) was found to contain compounds exhibiting antiviral properties, particularly effective against Dengue virus type 2 (DENV-2). Among these compounds, Caffeoylcalleryanin emerged as the most potent anti-DENV-2 agent, achieving a selectivity index (SI) of 20.0.</p>Formula:C22H24O11Colore e forma:SolidPeso molecolare:464.4Ferroleuton
<p>Ferroleuton is a selective competitive inhibitor of 5-lipoxygenase with an IC50 of 0.21 μM. It demonstrates antioxidant properties, clearing 86% of DPPH at 50 μM and exhibiting activities in ABTS (EC50 = 19.42 μM) and FRAP (EC50 = 3.32 μM) assays.</p>Formula:C13H16FeN2O2Colore e forma:SolidPeso molecolare:288.12Myxochelin A
CAS:<p>Myxochelin A from A. disciformis fights Gram-positive bacteria, inhibits 5-LO with IC50 of 1.9 μM, and is cytotoxic to colon cancer cells.</p>Formula:C20H24N2O7Colore e forma:SolidPeso molecolare:404.419CJ-13,610 hydrochloride
CAS:<p>CJ-13,610 hydrochloride is an orally active nonredox-type inhibitor of 5-LOX and can be used in studies about the prevention of untoward pathophysiological</p>Formula:C22H24ClN3O2SPurezza:98.5%Colore e forma:SoildPeso molecolare:429.96LOX-IN-5
CAS:<p>LOX-IN-5 (compound 22) is a non-selective LOX inhibitor.</p>Formula:C21H25FN4O2SColore e forma:SolidPeso molecolare:416.51Ruthenoleuton
<p>Ruthenoleuton is a 5-lipoxygenase (5-LOX) inhibitor with an IC50 of 3.49 μM and a Ki of 0.80 μM. It possesses antioxidant properties and is applicable in research on inflammatory diseases.</p>Formula:C13H16N2O2RuColore e forma:SolidPeso molecolare:333.35KKII5
CAS:<p>KKII5 is a potent inhibitor of the lipoxygenase LOX-1 with an IC50 of 19 μM.KKII5 inhibits lipid peroxidation and enhances the ability of the active centers of</p>Formula:C16H14N2SPurezza:99.34%Colore e forma:SolidPeso molecolare:266.36Lipoxygenase
CAS:<p>Lipoxygenase (LOX) is a dioxygenase that catalyzes the peroxidation of linoleic acid (LA) or arachidonic acid (AA) in the presence of molecular oxygen.</p>Colore e forma:SolidAureusidin
CAS:<p>Aureusidin (Auresidin) shows antioxidant and lipoxygenase inhibitory activity with anti-inflammatory effects.</p>Formula:C15H10O6Purezza:98.17% - 99.18%Colore e forma:SolidPeso molecolare:286.24Cinnamyl-3,4-dihydroxy-α-cyanocinnamate
CAS:<p>Cinnamyl-3,4-dihydroxy-α-cyanocinnamate (CDC), 12/15-LO inhibitor for diabetes. Affordable Excellence: Reliable Quality You Can Trust</p>Formula:C19H15NO4Colore e forma:SolidPeso molecolare:321.33Zileuton sodium
CAS:<p>Zileuton sodium (A 64077 sodium) is a potent and selective inhibitor of 5-lipoxygenase with anti-inflammatory activities.</p>Formula:C11H11N2NaO2SColore e forma:SolidPeso molecolare:258.274',5-Dihydroxyflavone
CAS:<p>4',5-Dihydroxyflavone is a soybean LOX-1(Ki: 102.6 μM) and yeast α-Glucosidase inhibitor (IC50: 66 μM).</p>Formula:C15H10O4Purezza:99.81%Colore e forma:SolidPeso molecolare:254.24Malotilate
CAS:<p>Malotilate (Kantec) is a medicine used for the therapy of liver cirrhosis.</p>Formula:C12H16O4S2Purezza:99.79% - 99.79%Colore e forma:SolidPeso molecolare:288.384-MMPB
CAS:<p>15-Lipoxygenase Inhibitor 1 is a selective inhibitor of 15-lipoxygenase, with an IC50 of 18 μM.</p>Formula:C16H19N5SPurezza:97.18%Colore e forma:SolidPeso molecolare:313.42Xanthatin
CAS:<p>Xanthatin exhibits cytotoxic, antibacterial, antifungal properties, may treat NSCLC, and inhibits melanoma by targeting Wnt/β-catenin and angiogenesis.</p>Formula:C15H18O3Purezza:98.48% - 99.96%Colore e forma:SolidPeso molecolare:246.3LOX-IN-3 dihydrochloride
CAS:<p>LOX-IN-3 dihydrochloride is an inhibitor of lysyl oxidase (LOX).</p>Formula:C13H15Cl2FN2O2SPurezza:99.96%Colore e forma:SolidPeso molecolare:353.24Phenethyl ferulate
CAS:<p>Phenethyl ferulate is a chemopreventive against colon cancer, enhancing apoptosis in tumors and inhibiting COX/5-LOX (IC50: 4.35/5.75 μM).</p>Formula:C18H18O4Purezza:99.88% - 99.91%Colore e forma:SolidPeso molecolare:298.33Phenidone
CAS:<p>Phenidone inhibits COX/LOX, reducing rat autoimmune paralysis and lowering blood pressure in hypertensive rats.</p>Formula:C9H10N2OPurezza:97.24%Colore e forma:White Solid Solid CrystallinePeso molecolare:162.19Chebulagic acid
CAS:<p>Chebulagic acid, isolated from the Terminalia chebula Retz, is a COX-LOX dual inhibitor.</p>Formula:C41H30O27Purezza:97.82% - 99.8%Colore e forma:SolidPeso molecolare:954.66Licofelone
CAS:<p>Licofelone (ML-3000) is a dual COX/LOX inhibitor potentially for the treatment of osteoarthritis.</p>Formula:C23H22ClNO2Purezza:99.25%Colore e forma:Yellowish SolidPeso molecolare:379.88S-(+)-Marmesin
CAS:<p>S-(+)-Marmesin (marmesin) is a coumarin originally isolated from the mature bark of A. marmelos,exhibiting COX-2/5-LOX dual inhibitory activity.</p>Formula:C14H14O4Purezza:98.00% - ≥98%Colore e forma:SolidPeso molecolare:246.26PGS-IN-1
CAS:<p>PGS-IN-1 (KME-4) is a potent inhibitor of prostaglandin synthetase (PGS, IC50: 0.28 μM) and 5-lipoxygenase (IC50: 1.05 μM).</p>Formula:C19H26O3Purezza:99.39%Colore e forma:SolidPeso molecolare:302.41Psoralidin
CAS:<p>Psoralidin inhibits Akt phosphorylation and phosphatidylinositol 3-kinase activation and transcriptionally.</p>Formula:C20H16O5Purezza:98% - 99.61%Colore e forma:SolidPeso molecolare:336.34SKF-86002
CAS:<p>SKF-86002 is an effective inhibitor of p38 MAP kinase (IC50: 0.5-1 uM); inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50: 1 μM).</p>Formula:C16H12FN3SPurezza:98% - 99.85%Colore e forma:SolidPeso molecolare:297.35Indirubin-3'-monoxime
CAS:<p>Indirubin-3'-monoxime (Indirubin-3'-oxime) is a potent inhibitor of GSK3β (IC50: 22 nM) and also inhibits CDKs ( (IC50s: 100/180/250 nM for Cdk5/p35, Cdk1/</p>Formula:C16H11N3O2Purezza:99.55%Colore e forma:Dark Red SolidPeso molecolare:277.283-O-Acetyl-11-hydroxy-β-boswellic acid
CAS:<p>3-O-Acetyl-11-hydroxy-beta-boswellic acid is the precursor of 3-O-acetyl-9, 11-dehydro-beta-boswellic acid(a 5-lipoxygenase inhibitor ).</p>Formula:C32H50O5Purezza:98.24%Colore e forma:SolidPeso molecolare:514.74Nordihydroguaiaretic acid
CAS:<p>Nordihydroguaiaretic acid (NDGA) is a natural lipoxygenase (5-LOX) inhibitor. Nordihydroguaiaretic acid has antioxidant effect. Cost-effective and quality-assured.</p>Formula:C18H22O4Purezza:97.82% - 99.91%Colore e forma:SolidPeso molecolare:302.36β-Aminopropionitrile hydrochloride
CAS:<p>β-Aminopropionitrile hydrochloride is a selective, oral, irreversible inhibitor of lysyl oxidase (LOX) that reduces metastatic seeding potential.</p>Formula:C3H7ClN2Purezza:99.32%Colore e forma:SolidPeso molecolare:106.55β-Boswellic acid
CAS:<p>β-Boswellic acid (Beta-boswellic acid) and its derivatives (the major constituents of Boswellin) have anti-carcinogenic, anti-tumor, and anti-hyperlipidemic</p>Formula:C30H48O3Purezza:99.2% - 99.91%Colore e forma:Off-White SolidPeso molecolare:456.7ETHYL 5-HYDROXY-2-METHYLINDOLE-3-CARBOXYLATE
CAS:<p>ETHYL 5-HYDROXY-2-METHYLINDOLE-3-CARBOXYLATE is useful for preparation and study of hypoxia-selective cytotoxicity of indolequinone antitumor agents.</p>Formula:C12H13NO3Purezza:98.9%Colore e forma:Off-White To Light Tan Crystalline PowderPeso molecolare:219.24BI-0115
CAS:<p>BI-0115 inhibits LOX-1, preventing oxLDL uptake by triggering receptor inhibition and dimer formation.</p>Formula:C15H14ClN3OPurezza:99.34%Colore e forma:SolidPeso molecolare:287.74Pectolinarigenin
CAS:<p>Pectolinarigenin has hepatoprotective and anti-inflammatory properties, acting through SOD and inhibiting eicosanoids.</p>Formula:C17H14O6Purezza:98.67% - 99.88%Colore e forma:SolidPeso molecolare:314.29Caffeic Acid
CAS:<p>Caffeic acid is a dual inhibitor of 5-lipoxygenase and TRPV1 ion channels. High-Quality, Low-Cost!</p>Formula:C9H8O4Purezza:98.89% - 99.3%Colore e forma:Yellow Crystals From Concentrated Aqueous Solutions Alkaline Solns Turn From Yellow To Orange Alkaline Solutions Turn From Yellow To Orange (Ntp 1992)Peso molecolare:180.162,5-Di-tert-butylhydroquinone
CAS:<p>2,5-Di-tert-butylhydroquinone (BHQ) is an effective and selective endoplasmic reticulum Ca2+-ATPase inhibitor.</p>Formula:C14H22O2Purezza:97.11%Colore e forma:PelletslargecrystalsPeso molecolare:222.32Tepoxalin
CAS:<p>Tepoxalin (RWJ 20485), potential asthma and osteoarthritis drug, inhibits COX-1, COX-2, and 5-LOX with low IC50 values.</p>Formula:C20H20ClN3O3Purezza:99.94%Colore e forma:SolidPeso molecolare:385.845-O-Demethylnobiletin
CAS:<p>5-O-Demethylnobiletin is a natural anti-inflammatory that inhibits 5-LOX without altering COX-2 expression.</p>Formula:C20H20O8Purezza:99.83% - ≥95%Colore e forma:SolidPeso molecolare:388.37FPL 62064
CAS:<p>FPL 62064 is a potent dual inhibitor of 5-lipoxygenase (5-LOX) and COX (IC50 of 3.5 μM and 3.1 μM for RBL-1 cytosolic 5-lipoxygenase and prostaglandin</p>Formula:C16H15N3OPurezza:98.79%Colore e forma:SolidPeso molecolare:265.31ML351
CAS:<p>ML351 is a potent and selective inhibitor of human 15-lipoxygenase-1 (15 LOX)(IC50: 200 nM).</p>Formula:C15H11N3OPurezza:97.67%Colore e forma:SolidPeso molecolare:249.27Linoleyl alcohol
CAS:<p>Linoleyl alcohol (CIS,CIS-9,12-OCTADECADIENOL), fatty alcohol, is a structural analog of Linoleic acid with no a-carboxyl group[1].</p>Formula:C18H34OPurezza:98.12%Colore e forma:SolidPeso molecolare:266.463-Hydroxycoumarin
CAS:<p>3-Hydroxycoumarin is a natural compound, and is human 15-LOX-1 inhibitors</p>Formula:C9H6O3Purezza:99.5% - 99.77%Colore e forma:SolidPeso molecolare:162.14ML355
CAS:<p>ML355, a specific, effective 12-Lipoxygenase(12-LOX) inhibitors(IC50=0.34 μM), possess favorable ADME properties.</p>Formula:C21H19N3O4S2Purezza:98.02% - 98.2%Colore e forma:SolidPeso molecolare:441.5211-Keto-β-boswellic acid
CAS:<p>11-Keto-beta-boswellic acid, a novel Nrf2 activator, and a selective 5-lipoxygenase (5-LOX) inhibitor, exerts dose dependent cardioprotective effect manifested.</p>Formula:C30H46O4Purezza:99.68%Colore e forma:SolidPeso molecolare:470.68Terameprocol
CAS:<p>Terameprocol (EM-1421), a synthetic NDGA derivative, shows potent anti-HIV, antiangiogenic, and anticancer properties.</p>Formula:C22H30O4Purezza:99.38%Colore e forma:SolidPeso molecolare:358.47Wedelolactone
CAS:<p>Wedelolactone (IKK Inhibitor II) inhibits NF-κB-mediated gene transcription in cells by blocking the phosphorylation and degradation of IκBα.</p>Formula:C16H10O7Purezza:98.07% - 99.87%Colore e forma:SolidPeso molecolare:314.25CAY10698
CAS:<p>CAY10698 is a 12-lipoxygenase inhibitor (12-LO; IC50 of 5.1 μM).</p>Formula:C17H17N3O4S2Purezza:98.97%Colore e forma:SolidPeso molecolare:391.46U-73122
CAS:<p>U-73122 (U73122) , an effective PLC inhibitor, reduces agonist-induced Ca2+ increases in platelets and PMN.</p>Formula:C29H40N2O3Purezza:97.50%Colore e forma:Solid Off-WhitePeso molecolare:464.645-LOX inhibitor
CAS:<p>5-LOX inhibitor (1-(sec-Butyl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one) is an itraconazole impurity, a LOX-5 inhibitor.</p>Formula:C22H27N5O2Purezza:98.01%Colore e forma:SolidPeso molecolare:393.48a-Boswellic Acid
CAS:Prodotto controllato<p>Applications The principal constitutents of frankincense (olibanum). A specific, nonredox inhibitor of 5-lipoxygenase used to treat inflammation.<br>References Safayhi, H. et al.: J. Pharmacol. Exp. Therap., 261, 1143 (1992); Siemoneit, U., et al.: Eur. J. Pharmacol., 606, 246 (2009); Cao, H. et al.: Pharamacol. Res., 61, 519 (2010);<br></p>Formula:C30H48O3Colore e forma:NeatPeso molecolare:456.70Golocdacimab
CAS:<p>Golocdacimab (anti-LOX-1 mAb) targets LOX-1, with potential applications for type 2 diabetes complications and preventing HAE attacks.</p>Purezza:95%Colore e forma:Liquid4-(2-Methylpropyl)benzenemethanol
CAS:Prodotto controllatoFormula:C11H16OColore e forma:NeatPeso molecolare:164.24tHGA
CAS:<p>tHGA is a potent inhibitor of lipoxygenase.</p>Formula:C18H24O4Purezza:98%Colore e forma:SolidPeso molecolare:304.382-TEDC
CAS:<p>2-TEDC: Potent LOX inhibitor, blocks 5-LOX, 12-LOX, 15-LOX (IC50: 0.09, 0.013, 0.5 μM); aids atherosclerosis research.</p>Formula:C16H13NO4SPurezza:99.75%Colore e forma:SolidPeso molecolare:315.34Lipoxygenin
CAS:<p>Lipoxygenin: IC50 of 5 μM inhibits 5-LO, hedgehog, TGF-β, activin A, BMP, Wnt signaling, and boosts cardiac marker TnnT in iPSCs.</p>Formula:C24H22N2O4Colore e forma:SolidPeso molecolare:402.44LY 269415
CAS:<p>LY 269415 is an anti-inflammatory agent with antioxidant properties in vitro and could be beneficial as therapeutic agents in inflammatory arthritis.</p>Formula:C19H28N2O2SColore e forma:SolidPeso molecolare:348.5Fluindione
CAS:<p>Fluindione is a hematologic drug.</p>Formula:C15H9FO2Colore e forma:SolidPeso molecolare:240.23L 652343
CAS:<p>L 652343 is an inhibitor of cyclooxygenase and 5-lipoxygenase in vitro. It also inhibits the synthesis of the products of both these pathways in whole cells.</p>Formula:C22H14F3NO2S2Colore e forma:SolidPeso molecolare:445.48Atreleuton
CAS:<p>Atreleuton (ABT-761), reversible oral 5-LO inhibitor, selectively blocks leukotriene formation.</p>Formula:C16H15FN2O2SPurezza:98%Colore e forma:SolidPeso molecolare:318.37RWJ 63556
CAS:<p>RWJ 63556 is an orally active inhibitor of COX-2 selective/5-lipoxygenase, shows anti-inflammatory activities.</p>Formula:C11H10FNO3S2Purezza:99.92%Colore e forma:SolidPeso molecolare:287.33PF-4191834
CAS:<p>PF-4191834: Non-iron, non-redox 5-LOX inhibitor, IC50 = 229 nM, 300x selective over 12/15-LOX, inactive on COX enzymes.</p>Formula:C22H23N3O2SPurezza:99.83% - 99.98%Colore e forma:SolidPeso molecolare:393.5SB 210661
CAS:SB 210661 is a potent and selective 5-lipoxygenase inhibitor.Formula:C16H14F2N2O4Purezza:98%Colore e forma:SolidPeso molecolare:336.29Enazadrem
CAS:<p>Enazadrem is a 5-lipoxygenase inhibitor with antiinflammatory activities.</p>Formula:C18H25N3OPurezza:98%Colore e forma:SolidPeso molecolare:299.41LY 221068
CAS:<p>LY 221068 is a potent antioxidant with anti-inflammatory activity.</p>Formula:C20H30N2O2SPurezza:98%Colore e forma:SolidPeso molecolare:362.53Texasin
CAS:<p>Texasin is a selective inhibitor of human leukocyte 5-lipoxygenase.</p>Formula:C16H12O5Purezza:98%Colore e forma:SolidPeso molecolare:284.26YS-121
CAS:<p>YS121 inhibits mPGES-1 (IC50=3.4μM) & 5-LOX (IC50=6.5μM), and lowers PGE2 in A549 cells (EC50=12μM).</p>Formula:C20H26ClN3O2SColore e forma:SolidPeso molecolare:407.96L-651392
CAS:<p>L-651392 is an inhibitor of leukotriene.</p>Formula:C14H10BrNO3SColore e forma:SolidPeso molecolare:352.2LP117
CAS:<p>LP117 is a novel and effective inhibitor of 5-Lipoxygenase (5-LO) product synthesis (IC50: 1.1 μM).</p>Formula:C21H23ClN4O2SPurezza:98%Colore e forma:SolidPeso molecolare:430.95Fenleuton
CAS:<p>Fenleuton is a 5-lipoxygenase inhibitor.</p>Formula:C17H15FN2O3Purezza:98%Colore e forma:SolidPeso molecolare:314.31RG 6866
CAS:RG 6866 is a inhibitor of 5-lipoxygenase.Formula:C16H17NO3Purezza:98%Colore e forma:SolidPeso molecolare:271.31HZ52
CAS:<p>HZ52: Potent reversible 5-LO inhibitor; IC50 0.7 μM; blocks LTs in human leukocytes.</p>Formula:C24H26ClN3O2SColore e forma:SolidPeso molecolare:456Cgp 8065
CAS:<p>Cgp 8065 is a filaricidal compound, a dithiocarbamate-derivative of amoscanate.</p>Formula:C16H15N3O4S2Colore e forma:SolidPeso molecolare:377.44ICI 211965
CAS:<p>ICI 211965 is a selective and orally potent of 5-Lipoxygenase (5-LPO).</p>Formula:C24H23NO2SPurezza:98%Colore e forma:SolidPeso molecolare:389.51L 656224
CAS:<p>L 656224 is a 5-LO inhibitor.</p>Formula:C20H21ClO3Purezza:98%Colore e forma:SolidPeso molecolare:344.83MLS000536924
CAS:<p>MLS000536924 is a potent and selective competitive human epithelial 15-lipoxygenase-2 inhibitor.</p>Formula:C16H15N3SColore e forma:SolidPeso molecolare:281.38BI-L 357
CAS:<p>BI-L 357, a prodrug of BL-L 226, is a selective, orally active inhibitor of 5-lipoxygenase.</p>Formula:C18H18O4SColore e forma:SolidPeso molecolare:330.4AHR-5333
CAS:<p>AHR-5333 an antiallergy agent.</p>Formula:C30H33F2NO4Purezza:98%Colore e forma:SolidPeso molecolare:509.58EP6
CAS:<p>EP6 blocks 5-LO, key in the AA cascade, reducing leukotrienes to curb inflammation and allergies.</p>Formula:C24H30N4OPurezza:98%Colore e forma:SolidPeso molecolare:390.52A-69412
CAS:<p>A-69412 is a reversible 5-lipoxygenase inhibitor, potentially treating ulcerative colitis and asthma.</p>Formula:C7H10N2O3Purezza:99.54%Colore e forma:SolidPeso molecolare:170.17Lonapalene
CAS:<p>Lonapalene is a topically effective inhibitor of 5-lipoxygenase.</p>Formula:C16H15ClO6Purezza:98.67% - 99.33%Colore e forma:SolidPeso molecolare:338.74Utreloxastat
CAS:<p>Utreloxastat (PTC857) is a novel 15-lipoxygenase inhibitor that can be used to study amyotrophic lateral sclerosis<br>.</p>Formula:C18H28O2Purezza:99.95%Colore e forma:SolidPeso molecolare:276.41S-2474
CAS:<p>S-2474, an inhibitor of COX-2 and 5-lipoxygenase, has anti-inflammatory and neuroprotective activities, and inhibits cell death.</p>Formula:C20H31NO3SPurezza:99.03%Colore e forma:SolidPeso molecolare:365.53Butibufen
CAS:<p>Butibufen (FF-106) is a non-steroidal anti-inflammatory compound and LOX inhibitor with analgesic and antipyretic activity for the study of rheumatic diseases.</p>Formula:C14H20O2Purezza:98.11% - 98.91%Colore e forma:SolidPeso molecolare:220.315-LOX-IN-1
CAS:<p>5-LOX-IN-1 is a 5-Lipoxygenase (5-LOX) inhibitor (IC50: 2.3 μM).5-LOX-IN-1 can be used for cancer research.</p>Formula:C20H18N2O2SPurezza:97.45%Colore e forma:SolidPeso molecolare:350.4317(S)-HpDHA
CAS:<p>17(S)-HpDHA, primarily produced by the 15-Lipoxygenase (LOX) isoenzymes h15-LOX-1 and h15-LOX-2 from docosahexaenoic acid (DHA), is a key regulator in epoxide synthesis through allosteric modulation. Additionally, it effectively inhibits platelet aggregation, demonstrating an EC50 of approximately 1 μM [1].</p>Formula:C22H32O4Colore e forma:SolidPeso molecolare:360.49A 79175
CAS:<p>A 79175 is a 5-lipoxygenase inhibitor that increases bone formation.</p>Formula:C15H13FN2O4Purezza:98%Colore e forma:SolidPeso molecolare:304.27AA 863
CAS:<p>AA 863 is a 5-lipoxygenase inhibitor, it inhibits the proliferation of human glioma cell lines in dose-dependent.</p>Formula:C21H26O5Purezza:98%Colore e forma:SolidPeso molecolare:358.43L 670630
CAS:<p>L 670630 is a potent and orally active 5-lipoxygenase inhibitor.</p>Formula:C25H26O3Purezza:98%Colore e forma:SolidPeso molecolare:374.47Benoxaprofen
CAS:<p>Benoxaprofen (NSC-299582) is a non-steroidal anti-inflammatory drug.</p>Formula:C16H12ClNO3Purezza:98.87%Colore e forma:SolidPeso molecolare:301.72MLS000545091
CAS:<p>MLS000545091 is a potent and selective human epithelial 15-lipoxygenase-2 mixed-type inhibitor.</p>Formula:C14H15ClN2OPurezza:99.84%Colore e forma:SolidPeso molecolare:262.735-Lipoxygenase-In-1
CAS:5-Lipoxygenase-In-1 (compound example 4.10) is a 5-Lipoxygenase inhibitor.Formula:C23H28N4O2SColore e forma:SolidPeso molecolare:424.56h15-LOX-2 inhibitor 1
CAS:<p>Compound 105 (h15-LOX-2 inhibitor 1) is a potent inhibitor of human epithelial 15-lipoxygenase-2 (h15-LOX-2), exhibiting an IC50 of 0.34 μM [1].</p>Formula:C17H13F3N2SPurezza:98%Colore e forma:SolidPeso molecolare:334.36CMI-392
CAS:<p>CMI-392 is a dual 5-lipoxygenase inhibitor and platelet-activating factor (PAF) receptor antagonist (IC50s: 100 and 10 nM).</p>Formula:C31H37ClN2O8SPurezza:98%Colore e forma:SolidPeso molecolare:633.155,6-dehydro Arachidonic Acid
CAS:<p>5,6-dehydro Arachidonic acid, an arachidonic acid analog with a 5,6 acetylene, inhibits 5-LO; Ki=15 μM in RBL cells, IC50=10 μM in guinea pig leukocytes.</p>Formula:C20H30O2Colore e forma:SolidPeso molecolare:302.45A 78773
CAS:<p>A 78773: potent reversible 5-lipoxygenase inhibitor; active in cells/tissues; targets inflammation, asthma, IBD.</p>Formula:C15H13FN2O4Colore e forma:SolidPeso molecolare:304.27CCT365623
CAS:<p>CCT365623: oral Lysyl Oxidase inhibitor, potent, selective, good pharmacokinetics, anti-metastatic.</p>Formula:C18H17NO4S3Purezza:97.299% - 99.49%Colore e forma:SolidPeso molecolare:407.53Setileuton
CAS:<p>Setileuton (MK0633) is a specific 5-LOX inhibitor and can be used in research on asthma and atherosclerosis.</p>Formula:C22H17F4N3O4Purezza:98.85% - 99.35%Colore e forma:SolidPeso molecolare:463.38PXS-6302 hydrochloride
CAS:<p>PXS-6302 hydrochloride is a potent irreversible lysine oxidase (LOX) inhibitor, inhibiting Bovine LOX, rh LOXL1, rh LOXL2, rh LOXL3, and rh LOXL4 with IC50 of 3</p>Formula:C10H11ClF3NO2SPurezza:99.89%Colore e forma:SoildPeso molecolare:301.71AZD 4407
CAS:<p>AZD 4407 is a potent inhibitor of 5-lipoxygenase.</p>Formula:C19H21NO3S2Purezza:98%Colore e forma:SolidPeso molecolare:375.5ALOX15-IN-1
<p>ALOX15-IN-1 (8b) inhibits rabbit/human ALOX15; IC50: 0.04 μM for LA, 2.06 μM for AA.</p>Formula:C24H31N3O5SColore e forma:SolidPeso molecolare:473.595-LOX/MAOs-IN-1
CAS:<p>Compound 3, known as 5-LOX/MAOs-IN-1, acts as an inhibitor of 5-LOX/MAOs and is an effective free radical scavenger, displaying antioxidant characteristics. It has demonstrated neuroprotective effects in cell models damaged by oxidative stress and is capable of activating the neurogenesis microenvironment in adult mouse neural stem cells. This compound is utilized in research focused on neurodegenerative diseases.</p>Formula:C18H18N2O2Colore e forma:SolidPeso molecolare:294.35L 691816
CAS:<p>L 691816 is an effective inhibitor of the 5-LO reaction.</p>Formula:C36H35ClN6OSPurezza:98%Colore e forma:SolidPeso molecolare:635.22h15-LOX-2 inhibitor 3
CAS:<p>Compound 13, identified as h15-LOX-2 inhibitor 3, exhibits inhibitory activity against h15-LOX, with IC50 and Ki values of 25 μM and 15.1 μM, respectively.</p>Formula:C22H13N5O3Colore e forma:SolidPeso molecolare:395.37ALOX15-IN-2
CAS:<p>ALOX15-IN-2: Potent ALOX15 inhibitor. IC50: 1.55 μM for LA; 2.79 μM for AA. Stops linoleic/arachidonic acid oxidation.</p>Formula:C23H29N3O4SPurezza:98.10%Colore e forma:SolidPeso molecolare:443.56CJ-13,610
CAS:CJ-13,610 is an orally active and nonredox-type inhibitor of 5-lipoxygenase (5-LOX). CJ-13,610 inhibits the biosynthesis of leukotriene B4 and regulates the expression of IL-6 mRNA in macrophages.Formula:C22H23N3O2SPurezza:99.64%Colore e forma:SolidPeso molecolare:393.5
