Lipossigenasi
Le lipossigenasi sono una famiglia di enzimi che catalizzano l'ossigenazione degli acidi grassi polinsaturi, portando alla produzione di mediatori lipidici bioattivi come i leucotrieni e le lipossine. Questi mediatori svolgono ruoli critici nell'infiammazione, nelle risposte immunitarie e nel cancro. Gli inibitori della lipossigenasi sono utilizzati per studiare il loro ruolo nelle malattie infiammatorie, nell'asma e nel cancro. Presso CymitQuimica, offriamo una varietà di inibitori della lipossigenasi per supportare la tua ricerca in infiammazione, oncologia e metabolismo lipidico.
Trovati 134 prodotti di "Lipossigenasi"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Zileuton
CAS:Zileuton (A 64077) inhibits 5-lipoxygenase, reduces leukotrienes, aids bronchodilation, lessens mucus/edema, and helps manage asthma symptoms.Formula:C11H12N2O2SPurezza:98.72% - 99.43%Colore e forma:Crystalline SolidPeso molecolare:236.29CJ-13,610 hydrochloride
CAS:CJ-13,610 hydrochloride is an orally active nonredox-type inhibitor of 5-LOX and can be used in studies about the prevention of untoward pathophysiologicalFormula:C22H24ClN3O2SPurezza:98.5%Colore e forma:SoildPeso molecolare:429.96Ref: TM-T27026L
1mg52,00€5mg92,00€1mL*10mM (DMSO)148,00€10mg158,00€25mg335,00€50mg500,00€100mg705,00€500mg1.485,00€Myxochelin A
CAS:Myxochelin A from A. disciformis fights Gram-positive bacteria, inhibits 5-LO with IC50 of 1.9 μM, and is cytotoxic to colon cancer cells.Formula:C20H24N2O7Colore e forma:SolidPeso molecolare:404.419KKII5
CAS:KKII5 is a potent inhibitor of the lipoxygenase LOX-1 with an IC50 of 19 μM.KKII5 inhibits lipid peroxidation and enhances the ability of the active centers ofFormula:C16H14N2SPurezza:99.44%Colore e forma:SolidPeso molecolare:266.36Ref: TM-T77288
2mg37,00€5mg56,00€1mL*10mM (DMSO)58,00€10mg84,00€25mg126,00€50mg197,00€100mg330,00€200mg472,00€5-Lipoxygenase-IN-3
CAS:Compound 14, a <1 μM 5-lipoxygenase inhibitor, researches inflammation, cancer, stroke, Alzheimer's.Formula:C19H16ClN5OColore e forma:SolidPeso molecolare:365.82mPGES-1/5-LOX-IN-1
mPGES-1/5-LOX-IN-1 (compound 3j) is a potent, orally active dual inhibitor of mPGES-1 and 5-LOX, with IC50 values of 0.92 and 1.89 µM, respectively. Additionally, mPGES-1/5-LOX-IN-1 exhibits anti-inflammatory properties.Formula:C20H22N4O6SPeso molecolare:446.12601ThioLox
CAS:ThioLox, a 15-LOX-1 inhibitor (IC50: 12 μM), has anti-inflammatory, neuroprotective benefits, and guards against glutamate toxicity.
Formula:C15H18N2OSPurezza:99.98%Colore e forma:SoildPeso molecolare:274.38Caffeoylcalleryanin
CAS:Caffeoylcalleryanin demonstrated potent inhibitory activity against 15-lipoxygenase (15-LOX), with an IC50 value of 1.59 μM. Furthermore, ethanol extract from A. pulchra leaves (EEAPL) was found to contain compounds exhibiting antiviral properties, particularly effective against Dengue virus type 2 (DENV-2). Among these compounds, Caffeoylcalleryanin emerged as the most potent anti-DENV-2 agent, achieving a selectivity index (SI) of 20.0.Formula:C22H24O11Colore e forma:SolidPeso molecolare:464.415-LOX-1 inhibitor 1
CAS:9c(i472) blocks 15-LO-1 (IC50=0.19μM), lowers NF-κB in RAW-Blue cells, & cuts Nos2/lipid peroxidation in RAW 264.7 at 0.2-5μM.Formula:C22H21ClN2O4Colore e forma:SolidPeso molecolare:412.87CMI977
CAS:CMI977 is a potent inhibitor of 5-Lipoxygenase (5-LO).Formula:C16H19FN2O4Purezza:98%Colore e forma:SolidPeso molecolare:322.33Ferroleuton
Ferroleuton is a selective competitive inhibitor of 5-lipoxygenase with an IC50 of 0.21 μM. It demonstrates antioxidant properties, clearing 86% of DPPH at 50 μM and exhibiting activities in ABTS (EC50 = 19.42 μM) and FRAP (EC50 = 3.32 μM) assays.Formula:C13H16FeN2O2Colore e forma:SolidPeso molecolare:288.12DKI5
CAS:DKI5, a LOX-1 inhibitor with 22.5 μM IC50, may exhibit anti-inflammatory, antioxidant, and anti-lipid peroxidation effects in vitro.Formula:C8H10N4SPurezza:97.08%Colore e forma:SoildPeso molecolare:194.26Lagunamycin
CAS:Lagunamycin is used as a novel 5-lipoxygenase inhibitor.Formula:C19H21N3O4Colore e forma:SolidPeso molecolare:355.39(±)15-HEDE
CAS:(±)15-HEDE is produced by non-enzymatic oxidation of 11,14-eicosadienoic acid.Formula:C20H36O3Colore e forma:SolidPeso molecolare:324.50513-epi-12-oxo Phytodienoic Acid
CAS:13-epi-12-oxo PDA is a lipoxygenase derivative of α-linolenic acid in green plant leaves, often isomerizing during extraction and storage.Formula:C18H28O3Colore e forma:SolidPeso molecolare:292.412-Methyl-1-naphthol
CAS:2-Methyl-1-naphthol is a prostaglandin G/H synthase and polyunsaturated fatty acid 5-lipoxygenase inhibitor, suitable for biochemical experiments.Formula:C11H10OPurezza:98.33%Colore e forma:SolidPeso molecolare:158.2LOX-IN-5
CAS:LOX-IN-5 (compound 22) is a non-selective LOX inhibitor.Formula:C21H25FN4O2SColore e forma:SolidPeso molecolare:416.515-LOX-IN-5
Compound 29, also known as 5-LOX-IN-5, is a 5-lipoxygenase (5-LOX) inhibitor with an inhibitory concentration 50 (IC50) of 56 nM, utilized in researchFormula:C19H18BrN3O2SPurezza:98%Colore e forma:SolidPeso molecolare:432.331-Naphthyl 3,5-dinitrobenzoate
CAS:1-Naphthyl 3,5-dinitrobenzoate (JMC-4) is an inhibitor of 5-LOX can be used in studies about inflammatory therapy.Formula:C17H10N2O6Purezza:99.79%Colore e forma:SolidPeso molecolare:338.27Ref: TM-T21838
5mg54,00€1mL*10mM (DMSO)55,00€10mg86,00€25mg161,00€50mg245,00€100mg346,00€200mg474,00€(-)-Dihydroguaiaretic acid
(-)-Dihydroguaiaretic acid is a useful organic compound for research related to life sciences and the catalog number is T126154.Formula:C20H26O4Colore e forma:SolidPeso molecolare:330.4245-LOX/NO-IN-1
5-LOX/NO-IN-1 (Compound 7e) is a dual inhibitor of 5-LOX and nitric oxide release. It exhibits an IC50 value of 2.833 μM for 5-LOX and demonstrates anti-inflammatory properties.Formula:C22H18N6O4Colore e forma:SolidPeso molecolare:430.42BLX3887
CAS:BLX3887 selectively inhibits 15-LO-1 (IC50 = 32 nM), not 15-LO-2, less on 5-LO/12-LO, and affects eosinophils and dendritic cells.Formula:C10H5Cl3FN3OColore e forma:SolidPeso molecolare:308.52ZD-2138
CAS:ZD-2138: Selective 5-LOX inhibitor, eases allergen-induced asthma attacks and airway constriction in guinea pigs.Formula:C23H24FNO4Purezza:99.68% - >99.99%Colore e forma:SolidPeso molecolare:397.44Lipoxygenase
CAS:Lipoxygenase (LOX) is a dioxygenase that catalyzes the peroxidation of linoleic acid (LA) or arachidonic acid (AA) in the presence of molecular oxygen.Colore e forma:SolidE 6080 HCl
CAS:E 6080 HCl is a 5-lipoxygenase inhibitor and can be used to study bronchial diseases.Formula:C17H20ClN3O3S2Purezza:99.80%Colore e forma:SoildPeso molecolare:413.94Ruthenoleuton
Ruthenoleuton is a 5-lipoxygenase (5-LOX) inhibitor with an IC50 of 3.49 μM and a Ki of 0.80 μM. It possesses antioxidant properties and is applicable in research on inflammatory diseases.Formula:C13H16N2O2RuColore e forma:SolidPeso molecolare:333.35h15-LOX-2 inhibitor 2
Compound 10 (h15-LOX-2 inhibitor 2) suppresses h15-LOX activity, exhibiting IC 50 and K i values of 26.9 μM and 16.4 μM, respectively.Formula:C22H30Cl2N6O3Colore e forma:SolidPeso molecolare:497.42Enazadrem phosphate
CAS:Enazadrem phosphate is a bio-active chemical. Detailed information has not been published.Formula:C18H28N3O5PColore e forma:SolidPeso molecolare:397.413-Chloroiminodibenzyl
CAS:Compound PDK0184, with CAS No. 32943-25-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0184 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C14H12ClNPeso molecolare:229.78(S)-HEPE
CAS:8(S)-HEPE, derived from EPA via lipoxygenase, aids barnacle egg hatching at 10 nM, but it's not confirmed as the natural hatching factor.Formula:C20H30O3Colore e forma:SolidPeso molecolare:318.457CBS-1114 HCl
CAS:CBS-1114 HCl: 5-lipoxygenase inhibitor, anti-inflammatory, improves heart function, reduces heart's fat.Formula:C13H14ClN3Purezza:99.93%Colore e forma:SoildPeso molecolare:247.72Damnacanthol
Damnacanthol is a useful organic compound for research related to life sciences and the catalog number is T131609.Formula:C16H12O5Colore e forma:SolidPeso molecolare:284.267Aureusidin
CAS:Aureusidin (Auresidin) shows antioxidant and lipoxygenase inhibitory activity with anti-inflammatory effects.Formula:C15H10O6Purezza:98.95% - 99.18%Colore e forma:SolidPeso molecolare:286.24Ref: TM-TN5634
1mg197,00€1mL*10mM (DMSO)384,00€5mg400,00€10mg590,00€25mg888,00€50mg1.243,00€100mg1.693,00€Zileuton sodium
CAS:Zileuton sodium (A 64077 sodium) is a potent and selective inhibitor of 5-lipoxygenase with anti-inflammatory activities.Formula:C11H11N2NaO2SColore e forma:SolidPeso molecolare:258.27Cinnamyl-3,4-dihydroxy-α-cyanocinnamate
CAS:Cinnamyl-3,4-dihydroxy-α-cyanocinnamate (CDC), 12/15-LO inhibitor for diabetes. Affordable Excellence: Reliable Quality You Can TrustFormula:C19H15NO4Colore e forma:SolidPeso molecolare:321.33Chebulagic acid
CAS:Chebulagic acid, isolated from the Terminalia chebula Retz, is a COX-LOX dual inhibitor.Formula:C41H30O27Purezza:97.82% - 99.8%Colore e forma:SolidPeso molecolare:954.66Ref: TM-TQ0180
1mg74,00€5mg157,00€10mg225,00€1mL*10mM (DMSO)244,00€25mg376,00€50mg560,00€100mg798,00€4-MMPB
CAS:15-Lipoxygenase Inhibitor 1 is a selective inhibitor of 15-lipoxygenase, with an IC50 of 18 μM.Formula:C16H19N5SPurezza:97.18%Colore e forma:SolidPeso molecolare:313.42Ref: TM-T8794
2mg34,00€5mg52,00€1mL*10mM (DMSO)58,00€10mg86,00€25mg156,00€50mg245,00€100mg403,00€200mg568,00€Phenidone
CAS:Phenidone inhibits COX/LOX, reducing rat autoimmune paralysis and lowering blood pressure in hypertensive rats.Formula:C9H10N2OPurezza:97.24%Colore e forma:White Solid Solid CrystallinePeso molecolare:162.19SKF-86002
CAS:SKF-86002 is an effective inhibitor of p38 MAP kinase (IC50: 0.5-1 uM); inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50: 1 μM).Formula:C16H12FN3SPurezza:98% - 99.85%Colore e forma:SolidPeso molecolare:297.35Phenethyl ferulate
CAS:Phenethyl ferulate is a chemopreventive against colon cancer, enhancing apoptosis in tumors and inhibiting COX/5-LOX (IC50: 4.35/5.75 μM).Formula:C18H18O4Purezza:99.88% - 99.91%Colore e forma:SolidPeso molecolare:298.33Ref: TM-TN2330
1mg56,00€1mL*10mM (DMSO)114,00€5mg119,00€10mg192,00€25mg323,00€50mg475,00€100mg687,00€Malotilate
CAS:Malotilate (Kantec) is a medicine used for the therapy of liver cirrhosis.Formula:C12H16O4S2Purezza:99.79% - 99.79%Colore e forma:SolidPeso molecolare:288.38Psoralidin
CAS:Psoralidin inhibits Akt phosphorylation and phosphatidylinositol 3-kinase activation and transcriptionally.Formula:C20H16O5Purezza:98% - 99.61%Colore e forma:SolidPeso molecolare:336.34Ref: TM-T3399
2mg34,00€5mg50,00€1mL*10mM (DMSO)55,00€10mg81,00€25mg152,00€50mg230,00€100mg340,00€200mg497,00€PGS-IN-1
CAS:PGS-IN-1 (KME-4) is a potent inhibitor of prostaglandin synthetase (PGS, IC50: 0.28 μM) and 5-lipoxygenase (IC50: 1.05 μM).Formula:C19H26O3Purezza:99.39%Colore e forma:SolidPeso molecolare:302.41BI-0115
CAS:BI-0115 inhibits LOX-1, preventing oxLDL uptake by triggering receptor inhibition and dimer formation.Formula:C15H14ClN3OPurezza:99.34%Colore e forma:SolidPeso molecolare:287.74S-(+)-Marmesin
CAS:S-(+)-Marmesin (marmesin) is a coumarin originally isolated from the mature bark of A. marmelos,exhibiting COX-2/5-LOX dual inhibitory activity.Formula:C14H14O4Purezza:98.00% - ≥98%Colore e forma:SolidPeso molecolare:246.26Xanthatin
CAS:Xanthatin exhibits cytotoxic, antibacterial, antifungal properties, may treat NSCLC, and inhibits melanoma by targeting Wnt/β-catenin and angiogenesis.Formula:C15H18O3Purezza:98.48% - 99.96%Colore e forma:SolidPeso molecolare:246.3Ref: TM-T3S0153
50mgPrezzo su richiesta1mg49,00€5mg92,00€1mL*10mM (DMSO)113,00€10mg166,00€25mg268,00€Pectolinarigenin
CAS:Pectolinarigenin has hepatoprotective and anti-inflammatory properties, acting through SOD and inhibiting eicosanoids.Formula:C17H14O6Purezza:98.67% - 99.88%Colore e forma:SolidPeso molecolare:314.29Ref: TM-T6S0413
1mg46,00€5mg89,00€1mL*10mM (DMSO)110,00€10mg154,00€25mg265,00€50mg409,00€100mg620,00€Indirubin-3'-monoxime
CAS:Indirubin-3'-monoxime (Indirubin-3'-oxime) is a potent inhibitor of GSK3β (IC50: 22 nM) and also inhibits CDKs ( (IC50s: 100/180/250 nM for Cdk5/p35, Cdk1/Formula:C16H11N3O2Purezza:99.55%Colore e forma:Dark Red SolidPeso molecolare:277.28ETHYL 5-HYDROXY-2-METHYLINDOLE-3-CARBOXYLATE
CAS:ETHYL 5-HYDROXY-2-METHYLINDOLE-3-CARBOXYLATE is useful for preparation and study of hypoxia-selective cytotoxicity of indolequinone antitumor agents.Formula:C12H13NO3Purezza:98.9%Colore e forma:Off-White To Light Tan Crystalline PowderPeso molecolare:219.243-O-Acetyl-11-hydroxy-β-boswellic acid
CAS:3-O-Acetyl-11-hydroxy-beta-boswellic acid is the precursor of 3-O-acetyl-9, 11-dehydro-beta-boswellic acid(a 5-lipoxygenase inhibitor ).Formula:C32H50O5Purezza:98.24%Colore e forma:SolidPeso molecolare:514.74
