Lipossigenasi
Le lipossigenasi sono una famiglia di enzimi che catalizzano l'ossigenazione degli acidi grassi polinsaturi, portando alla produzione di mediatori lipidici bioattivi come i leucotrieni e le lipossine. Questi mediatori svolgono ruoli critici nell'infiammazione, nelle risposte immunitarie e nel cancro. Gli inibitori della lipossigenasi sono utilizzati per studiare il loro ruolo nelle malattie infiammatorie, nell'asma e nel cancro. Presso CymitQuimica, offriamo una varietà di inibitori della lipossigenasi per supportare la tua ricerca in infiammazione, oncologia e metabolismo lipidico.
Trovati 124 prodotti di "Lipossigenasi"
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Zileuton
CAS:<p>Zileuton (A 64077) inhibits 5-lipoxygenase, reduces leukotrienes, aids bronchodilation, lessens mucus/edema, and helps manage asthma symptoms.</p>Formula:C11H12N2O2SPurezza:98.72% - 99.43%Colore e forma:Crystalline SolidPeso molecolare:236.29Meclofenoxate hydrochloride
CAS:<p>Meclofenoxate HCl (Lucidril) boosts memory and cognition; it's a DIMETHYLAMINOETHANOL and p-chlorophenoxyacetic acid ester.</p>Formula:C12H16ClNO3·HClPurezza:97.05%Colore e forma:White Crystal PowderPeso molecolare:294.17Diethylcarbamazine citrate
CAS:<p>Diethylcarbamazine citrate treats filariasis, targeting W. bancrofti and L. loa by inhibiting arachidonic acid in microfilaria.</p>Formula:C10H21N3O·C6H8O7Purezza:99.61%Colore e forma:White Crystalline Powder And Animals (Epa 1998)Peso molecolare:391.42mPGES-1/5-LOX-IN-1
mPGES-1/5-LOX-IN-1 (compound 3j) is a potent, orally active dual inhibitor of mPGES-1 and 5-LOX, with IC50 values of 0.92 and 1.89 µM, respectively. Additionally, mPGES-1/5-LOX-IN-1 exhibits anti-inflammatory properties.Formula:C20H22N4O6SPeso molecolare:446.12601Damnacanthol
<p>Damnacanthol is a useful organic compound for research related to life sciences and the catalog number is T131609.</p>Formula:C16H12O5Colore e forma:SolidPeso molecolare:284.267Lipoxygenase
CAS:<p>Lipoxygenase (LOX) is a dioxygenase that catalyzes the peroxidation of linoleic acid (LA) or arachidonic acid (AA) in the presence of molecular oxygen.</p>Colore e forma:SolidCMI977
CAS:<p>CMI977 is a potent inhibitor of 5-Lipoxygenase (5-LO).</p>Formula:C16H19FN2O4Purezza:98%Colore e forma:SolidPeso molecolare:322.3315-LOX-1 inhibitor 1
CAS:<p>9c(i472) blocks 15-LO-1 (IC50=0.19μM), lowers NF-κB in RAW-Blue cells, & cuts Nos2/lipid peroxidation in RAW 264.7 at 0.2-5μM.</p>Formula:C22H21ClN2O4Colore e forma:SolidPeso molecolare:412.875-LOX/NO-IN-1
<p>5-LOX/NO-IN-1 (Compound 7e) is a dual inhibitor of 5-LOX and nitric oxide release. It exhibits an IC50 value of 2.833 μM for 5-LOX and demonstrates anti-inflammatory properties.</p>Formula:C22H18N6O4Colore e forma:SolidPeso molecolare:430.42DKI5
CAS:<p>DKI5, a LOX-1 inhibitor with 22.5 μM IC50, may exhibit anti-inflammatory, antioxidant, and anti-lipid peroxidation effects in vitro.</p>Formula:C8H10N4SPurezza:98%Colore e forma:SoildPeso molecolare:194.26h15-LOX-2 inhibitor 2
Compound 10 (h15-LOX-2 inhibitor 2) suppresses h15-LOX activity, exhibiting IC 50 and K i values of 26.9 μM and 16.4 μM, respectively.Formula:C22H30Cl2N6O3Colore e forma:SolidPeso molecolare:497.42ThioLox
CAS:<p>ThioLox, a 15-LOX-1 inhibitor (IC50: 12 μM), has anti-inflammatory, neuroprotective benefits, and guards against glutamate toxicity.</p>Formula:C15H18N2OSPurezza:99.98%Colore e forma:SoildPeso molecolare:274.38Ruthenoleuton
<p>Ruthenoleuton is a 5-lipoxygenase (5-LOX) inhibitor with an IC50 of 3.49 μM and a Ki of 0.80 μM. It possesses antioxidant properties and is applicable in research on inflammatory diseases.</p>Formula:C13H16N2O2RuColore e forma:SolidPeso molecolare:333.35Aureusidin
CAS:<p>Aureusidin (Auresidin) shows antioxidant and lipoxygenase inhibitory activity with anti-inflammatory effects.</p>Formula:C15H10O6Purezza:98.17% - 99.18%Colore e forma:SolidPeso molecolare:286.24CJ-13,610 hydrochloride
CAS:<p>CJ-13,610 hydrochloride is an orally active nonredox-type inhibitor of 5-LOX and can be used in studies about the prevention of untoward pathophysiological</p>Formula:C22H24ClN3O2SPurezza:98.5%Colore e forma:SoildPeso molecolare:429.96Ferroleuton
<p>Ferroleuton is a selective competitive inhibitor of 5-lipoxygenase with an IC50 of 0.21 μM. It demonstrates antioxidant properties, clearing 86% of DPPH at 50 μM and exhibiting activities in ABTS (EC50 = 19.42 μM) and FRAP (EC50 = 3.32 μM) assays.</p>Formula:C13H16FeN2O2Colore e forma:SolidPeso molecolare:288.125-LOX-IN-5
<p>Compound 29, also known as 5-LOX-IN-5, is a 5-lipoxygenase (5-LOX) inhibitor with an inhibitory concentration 50 (IC50) of 56 nM, utilized in research</p>Formula:C19H18BrN3O2SPurezza:98%Colore e forma:SolidPeso molecolare:432.33LOX-IN-5
CAS:<p>LOX-IN-5 (compound 22) is a non-selective LOX inhibitor.</p>Formula:C21H25FN4O2SColore e forma:SolidPeso molecolare:416.51(±)15-HEDE
CAS:<p>(±)15-HEDE is produced by non-enzymatic oxidation of 11,14-eicosadienoic acid.</p>Formula:C20H36O3Colore e forma:SolidPeso molecolare:324.50513-epi-12-oxo Phytodienoic Acid
CAS:<p>13-epi-12-oxo PDA is a lipoxygenase derivative of α-linolenic acid in green plant leaves, often isomerizing during extraction and storage.</p>Formula:C18H28O3Colore e forma:SolidPeso molecolare:292.41Myxochelin A
CAS:<p>Myxochelin A from A. disciformis fights Gram-positive bacteria, inhibits 5-LO with IC50 of 1.9 μM, and is cytotoxic to colon cancer cells.</p>Formula:C20H24N2O7Colore e forma:SolidPeso molecolare:404.4191-Naphthyl 3,5-dinitrobenzoate
CAS:<p>1-Naphthyl 3,5-dinitrobenzoate (JMC-4) is an inhibitor of 5-LOX can be used in studies about inflammatory therapy.</p>Formula:C17H10N2O6Purezza:99.79%Colore e forma:SolidPeso molecolare:338.27(-)-Dihydroguaiaretic acid
<p>(-)-Dihydroguaiaretic acid is a useful organic compound for research related to life sciences and the catalog number is T126154.</p>Formula:C20H26O4Colore e forma:SolidPeso molecolare:330.424ZD-2138
CAS:<p>ZD-2138: Selective 5-LOX inhibitor, eases allergen-induced asthma attacks and airway constriction in guinea pigs.</p>Formula:C23H24FNO4Purezza:99.68% - >99.99%Colore e forma:SolidPeso molecolare:397.44Lagunamycin
CAS:<p>Lagunamycin is used as a novel 5-lipoxygenase inhibitor.</p>Formula:C19H21N3O4Colore e forma:SolidPeso molecolare:355.392-Methyl-1-naphthol
CAS:<p>2-Methyl-1-naphthol is a prostaglandin G/H synthase and polyunsaturated fatty acid 5-lipoxygenase inhibitor, suitable for biochemical experiments.</p>Formula:C11H10OPurezza:98.33%Colore e forma:SolidPeso molecolare:158.2KKII5
CAS:<p>KKII5 is a potent inhibitor of the lipoxygenase LOX-1 with an IC50 of 19 μM.KKII5 inhibits lipid peroxidation and enhances the ability of the active centers of</p>Formula:C16H14N2SPurezza:99.34%Colore e forma:SolidPeso molecolare:266.36E 6080 HCl
CAS:<p>E 6080 HCl is a 5-lipoxygenase inhibitor and can be used to study bronchial diseases.</p>Formula:C17H20ClN3O3S2Purezza:99.80%Colore e forma:SoildPeso molecolare:413.945-Lipoxygenase-IN-3
CAS:<p>Compound 14, a <1 μM 5-lipoxygenase inhibitor, researches inflammation, cancer, stroke, Alzheimer's.</p>Formula:C19H16ClN5OColore e forma:SolidPeso molecolare:365.82Caffeoylcalleryanin
CAS:<p>Caffeoylcalleryanin demonstrated potent inhibitory activity against 15-lipoxygenase (15-LOX), with an IC50 value of 1.59 μM. Furthermore, ethanol extract from A. pulchra leaves (EEAPL) was found to contain compounds exhibiting antiviral properties, particularly effective against Dengue virus type 2 (DENV-2). Among these compounds, Caffeoylcalleryanin emerged as the most potent anti-DENV-2 agent, achieving a selectivity index (SI) of 20.0.</p>Formula:C22H24O11Colore e forma:SolidPeso molecolare:464.4CBS-1114 HCl
CAS:<p>CBS-1114 HCl: 5-lipoxygenase inhibitor, anti-inflammatory, improves heart function, reduces heart's fat.</p>Formula:C13H14ClN3Purezza:99.36%Colore e forma:SoildPeso molecolare:247.72Zileuton sodium
CAS:<p>Zileuton sodium (A 64077 sodium) is a potent and selective inhibitor of 5-lipoxygenase with anti-inflammatory activities.</p>Formula:C11H11N2NaO2SColore e forma:SolidPeso molecolare:258.27Cinnamyl-3,4-dihydroxy-α-cyanocinnamate
CAS:<p>Cinnamyl-3,4-dihydroxy-α-cyanocinnamate (CDC), 12/15-LO inhibitor for diabetes. Affordable Excellence: Reliable Quality You Can Trust</p>Formula:C19H15NO4Colore e forma:SolidPeso molecolare:321.33Phenidone
CAS:Phenidone inhibits COX/LOX, reducing rat autoimmune paralysis and lowering blood pressure in hypertensive rats.Formula:C9H10N2OPurezza:97.24%Colore e forma:White Solid Solid CrystallinePeso molecolare:162.19Malotilate
CAS:<p>Malotilate (Kantec) is a medicine used for the therapy of liver cirrhosis.</p>Formula:C12H16O4S2Purezza:99.79% - 99.79%Colore e forma:SolidPeso molecolare:288.38SKF-86002
CAS:<p>SKF-86002 is an effective inhibitor of p38 MAP kinase (IC50: 0.5-1 uM); inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50: 1 μM).</p>Formula:C16H12FN3SPurezza:98% - 99.85%Colore e forma:SolidPeso molecolare:297.35Phenethyl ferulate
CAS:<p>Phenethyl ferulate is a chemopreventive against colon cancer, enhancing apoptosis in tumors and inhibiting COX/5-LOX (IC50: 4.35/5.75 μM).</p>Formula:C18H18O4Purezza:99.88% - 99.91%Colore e forma:SolidPeso molecolare:298.33Caffeic Acid
CAS:<p>Caffeic acid is a dual inhibitor of 5-lipoxygenase and TRPV1 ion channels. High-Quality, Low-Cost!</p>Formula:C9H8O4Purezza:98.89% - 99.3%Colore e forma:Yellow Crystals From Concentrated Aqueous Solutions Alkaline Solns Turn From Yellow To Orange Alkaline Solutions Turn From Yellow To Orange (Ntp 1992)Peso molecolare:180.164',5-Dihydroxyflavone
CAS:<p>4',5-Dihydroxyflavone is a soybean LOX-1(Ki: 102.6 μM) and yeast α-Glucosidase inhibitor (IC50: 66 μM).</p>Formula:C15H10O4Purezza:99.81%Colore e forma:SolidPeso molecolare:254.24BI-0115
CAS:BI-0115 inhibits LOX-1, preventing oxLDL uptake by triggering receptor inhibition and dimer formation.Formula:C15H14ClN3OPurezza:99.34%Colore e forma:SolidPeso molecolare:287.74PGS-IN-1
CAS:<p>PGS-IN-1 (KME-4) is a potent inhibitor of prostaglandin synthetase (PGS, IC50: 0.28 μM) and 5-lipoxygenase (IC50: 1.05 μM).</p>Formula:C19H26O3Purezza:99.39%Colore e forma:SolidPeso molecolare:302.41Pectolinarigenin
CAS:<p>Pectolinarigenin has hepatoprotective and anti-inflammatory properties, acting through SOD and inhibiting eicosanoids.</p>Formula:C17H14O6Purezza:98.67% - 99.88%Colore e forma:SolidPeso molecolare:314.29Indirubin-3'-monoxime
CAS:<p>Indirubin-3'-monoxime (Indirubin-3'-oxime) is a potent inhibitor of GSK3β (IC50: 22 nM) and also inhibits CDKs ( (IC50s: 100/180/250 nM for Cdk5/p35, Cdk1/</p>Formula:C16H11N3O2Purezza:99.55%Colore e forma:Dark Red SolidPeso molecolare:277.28S-(+)-Marmesin
CAS:S-(+)-Marmesin (marmesin) is a coumarin originally isolated from the mature bark of A. marmelos,exhibiting COX-2/5-LOX dual inhibitory activity.Formula:C14H14O4Purezza:98.00% - ≥98%Colore e forma:SolidPeso molecolare:246.26LOX-IN-3 dihydrochloride
CAS:<p>LOX-IN-3 dihydrochloride is an inhibitor of lysyl oxidase (LOX).</p>Formula:C13H15Cl2FN2O2SPurezza:99.96%Colore e forma:SolidPeso molecolare:353.24Psoralidin
CAS:Psoralidin inhibits Akt phosphorylation and phosphatidylinositol 3-kinase activation and transcriptionally.Formula:C20H16O5Purezza:98% - 99.61%Colore e forma:SolidPeso molecolare:336.34ETHYL 5-HYDROXY-2-METHYLINDOLE-3-CARBOXYLATE
CAS:<p>ETHYL 5-HYDROXY-2-METHYLINDOLE-3-CARBOXYLATE is useful for preparation and study of hypoxia-selective cytotoxicity of indolequinone antitumor agents.</p>Formula:C12H13NO3Purezza:98.9%Colore e forma:Off-White To Light Tan Crystalline PowderPeso molecolare:219.24Nordihydroguaiaretic acid
CAS:<p>Nordihydroguaiaretic acid (NDGA) is a natural lipoxygenase (5-LOX) inhibitor. Nordihydroguaiaretic acid has antioxidant effect. Cost-effective and quality-assured.</p>Formula:C18H22O4Purezza:97.82% - 99.91%Colore e forma:SolidPeso molecolare:302.36β-Aminopropionitrile hydrochloride
CAS:<p>β-Aminopropionitrile hydrochloride is a selective, oral, irreversible inhibitor of lysyl oxidase (LOX) that reduces metastatic seeding potential.</p>Formula:C3H7ClN2Purezza:99.32%Colore e forma:SolidPeso molecolare:106.55Xanthatin
CAS:Xanthatin exhibits cytotoxic, antibacterial, antifungal properties, may treat NSCLC, and inhibits melanoma by targeting Wnt/β-catenin and angiogenesis.Formula:C15H18O3Purezza:98.48% - 99.96%Colore e forma:SolidPeso molecolare:246.3
