Fosfolipasi
Le fosfolipasi sono un gruppo di enzimi che idrolizzano i fosfolipidi in acidi grassi e altre sostanze lipofile, svolgendo un ruolo critico nella biologia delle membrane e nella generazione di molecole segnalatrici. Gli inibitori delle fosfolipasi vengono utilizzati per studiare il loro ruolo nelle malattie infiammatorie, nei disturbi cardiovascolari e nella neurodegenerazione. Questi inibitori sono anche preziosi per esplorare le vie di segnalazione lipidica e le loro implicazioni nei meccanismi delle malattie. Presso CymitQuimica, offriamo una varietà di inibitori delle fosfolipasi per supportare la tua ricerca in infiammazione, metabolismo lipidico e segnalazione cellulare.
Trovati 84 prodotti per "Fosfolipasi".
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Tris(2,4-di-tert-butylphenyl)phosphate
CAS:Tris(2,4-di-tert-butylphenyl)phosphate (TDTBPP) inhibits secretory phospholipase A2 (sPLA2) with anti-inflammatory effect. Cost-effective and quality-assured.Formula:C42H63O4PPurezza:99.73%Colore e forma:SolidPeso molecolare:662.92ML349
CAS:ML349 is an inhibitor of LYPLA2 (IC50: 144 nM). ML349 is an effective and specific acyl protein thioesterase 2 (APT-2) inhibitor (Ki: 120 nM).Formula:C23H22N2O4S2Purezza:99.59% - 99.88%Colore e forma:SolidPeso molecolare:454.56Omeprazole
CAS:Omeprazole (Losec) is a proton pump inhibitor (PPI), Omeprazole(Losec) is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor.Formula:C17H19N3O3SPurezza:98.43% - 98.48%Colore e forma:Brown SolidPeso molecolare:345.42Lp-PLA2-IN-1
CAS:Lp-PLA2-IN-1 suppresses Lp-PLA2, aiding in treating atherosclerosis and Alzheimer's.Formula:C21H17F5N4O3Purezza:99.60%Colore e forma:White SolidPeso molecolare:468.38Lansoprazole
CAS:Lansoprazole (A-65006) is a 2, 2, 2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISONFormula:C16H14F3N3O2SPurezza:99.18% - 99.84%Colore e forma:Yellow SolidPeso molecolare:369.36Compound 48/80 trihydrochloride
CAS:Compound 48/80 trihydrochloride (C48/80 trihydrochloride) is a mixture of N-methyl-p-methoxyphenethylamine and formaldehyde produced via a condensation reaction.Formula:C32H48Cl3N3O3Purezza:98% - 99.24%Colore e forma:White SolidPeso molecolare:629.1AACOCF3
CAS:AACOCF3 (Arachidonyl trifluoromethyl ketone) is a cell-permeable trifluoromethyl ketone analog of arachidonic acid.Formula:C21H31F3OPurezza:99% - 99%Colore e forma:SolidPeso molecolare:356.47A3373
CAS:A3373 is a novel inhibitor targeting both Phospholipase D1 (PLD1) and Phospholipase D2 (PLD2), demonstrating half maximal inhibitory concentrations (IC50) ofFormula:C17H9F7N2OPurezza:98%Colore e forma:SolidPeso molecolare:390.26ASM-IN-3
CAS:ASM-IN-3 (Compound 21b) is a selective acid sphingomyelinase (ASM) inhibitor that can penetrate the blood-brain barrier, with an IC50 of 3.37 μM against purified human ASM. By inhibiting ASM activity in the hippocampus and promoting neurogenesis, ASM-IN-3 alleviates depressive-like behavior in reserpine-induced depressive rats.Formula:C17H13ClN2O4Colore e forma:SolidPeso molecolare:344.75DPTIP
CAS:DPTIP is an effective inhibitor of neutral sphingomyelinase 2 with an IC50 value of 30 nM.Formula:C21H18N2O3SPurezza:99.88%Colore e forma:SolidPeso molecolare:378.44Ref: TM-T60043
1mg46,00€2mg59,00€5mg90,00€1mL*10mM (DMSO)90,00€10mg144,00€25mg281,00€50mg462,00€100mg672,00€A4333
A4333, a biotinylated derivative of A3373, selectively inhibits Phospholipase D1 (PLD1) while sparing PLD2.Purezza:98%Colore e forma:Odour Solid1,2-Bis(heptanoylthio)-sn-glycero-3-PG sodium
1,2-Bis(heptanoylthio)-sn-glycero-3-PG [1,2-Bis(heptanoylthio) glycerophosphatidylglycerol] sodium is a thioesterified phosphatidylglycerol derivative. It can be utilized to mimic phospholipase activity or serve as a probe molecule in membrane fusion studies.Colore e forma:Odour SolidLEI110
CAS:LEI110 inhibits PLA2G16 and HRASLS enzymes, Ki 20 nM, selectively targets related thiol hydrolases.Formula:C25H23F3N2O3Purezza:98.66% - 99.01%Colore e forma:SolidPeso molecolare:456.46PLA2-IN-1
PLA2-IN-1 (Compound 7) is a potent and selective inhibitor of phospholipase A (PLA2) with an IC50 value of 1 nM. It effectively inhibits PLA2-induced coagulation disorders in vitro and shows potential for use as an antidote for snake bites caused by cobra venom.Colore e forma:Odour SolidVU533
CAS:VU533 is a NAPE-PLD activator, EC50=0.30 µM, boosts macrophage activity, potential in cardiometabolic diseases.Formula:C21H22FN3O3S2Purezza:99.87%Colore e forma:SolidPeso molecolare:447.55sPLA2 inhibitor 2
sPLA2 inhibitor 2 (compound 6a) is an sPLA2 inhibitor with an IC50 value of 0.0475 μM, making it valuable for diabetes research.Formula:C20H18N6O4S2Colore e forma:SolidPeso molecolare:470.521-Myristoyl-2-Linoleoyl-sn-glycero-3-PC
CAS:1-Myristoyl-2-Linoleoyl-sn-glycero-3-PC is a phospholipid identified in human plasma, characterized by the presence of Myristic acid and Linoleic acid at the sn-1 and sn-2 positions, respectively.Formula:C40H76NO8PColore e forma:SolidPeso molecolare:730.01nSMase2-IN-1
nSMase2-IN-1 is an orally active inhibitor of Neutral sphingomyelinase 2 (nSMase2) with a potent IC50 value of 0.13 ± 0.06 μM.Formula:C12H17N5OPurezza:98%Colore e forma:SolidPeso molecolare:247.3Melittin Acetate
Melittin Acetate, a PLA2 activator, enhances low-weight PLA2 activity but not high-weight PLA2.Formula:C133H233N39O33Purezza:99.65%Colore e forma:SolidPeso molecolare:2906.51SB-435495
CAS:SB-435495 is a compound characterized by its potent, selective, reversible, and non-covalent inhibition of Lp-PLA2, demonstrating an IC50 value of 0.06 nM.Formula:C38H40F4N6O2SPurezza:99.07%Colore e forma:White SolidPeso molecolare:720.82
