Microbiologia/Virologia
Gli inibitori in microbiologia e virologia sono composti che bersagliano microrganismi, inclusi batteri, virus e funghi, interrompendo la loro crescita, replicazione o sopravvivenza. Questi inibitori sono essenziali per studiare la patogenesi microbica, comprendere i meccanismi di resistenza e sviluppare nuove terapie antimicrobiche e antivirali. Gli inibitori in questa categoria vengono utilizzati per combattere le malattie infettive, esplorare l'ecologia microbica e studiare le interazioni ospite-patogeno. Presso CymitQuimica, offriamo un'ampia selezione di inibitori di alta qualità in microbiologia e virologia per supportare la tua ricerca in malattie infettive, microbiologia e virologia.
Sottocategorie di "Microbiologia/Virologia"
- Antibatterico(3.153 prodotti)
- Antibiotico(932 prodotti)
- Antinfettivo(24 prodotti)
- DHFR(34 prodotti)
- Sintesi del DNA/RNA(774 prodotti)
- HBV(182 prodotti)
- Proteasi HIV(477 prodotti)
- HSV(94 prodotti)
- Integrasi(2 prodotti)
- Ribosoma(13 prodotti)
Mostrare 2 più sottocategorie
Trovati 6158 prodotti di "Microbiologia/Virologia"
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TCMDC-136230
TCMDC-136230 is a novel inhibitor of Plasmodium calcium kinetics with minimal inhibition of haemoglobin crystallisation.Formula:C24H34N4O2SColore e forma:SolidPeso molecolare:442.62LasR antagonist 1
CAS:LasR antagonist 1 (Compound 7), with an IC50 of 0.4 μM, is an effective antagonist of LasR that modulates quorum sensing (QS) in the opportunistic pathogen Pseudomonas aeruginosa [1].Formula:C20H15F3N2O3Colore e forma:SolidPeso molecolare:388.34RSV-IN-5
CAS:<p>RSV-IN-5: Dual inhibitor for RSV fusion proteins, effective on wild-type A2 and D486N mutant with EC50s of 2.0 nM & 8.1 nM. Potent anti-RSV.</p>Formula:C28H37N7O2Colore e forma:SolidPeso molecolare:503.64NRTT-IN-1
CAS:<p>NRTT-IN-1 (Compound 1) is an inhibitor of the nucleoside reverse transcriptase translocation (NRTT), effectively blocking HIV DNA synthesis and viral replication.</p>Formula:C28H24FN5O5Colore e forma:SolidPeso molecolare:529.519Xeruborbactam isoboxil
CAS:<p>Xeruborbactam isoboxil is a β-lactamase (beta-lactamase) inhibitor.</p>Formula:C15H16BFO6Colore e forma:SolidPeso molecolare:322.093SP-471
SP-471 is a potent inhibitor of dengue virus (DENV) protease (IC50: 18 μM) and inhibits the inter- and intramolecular protease processes of DENV.Formula:C33H26BrN5Colore e forma:SolidPeso molecolare:572.5Pol I-IN-1
Pol I-IN-1 is a powerful inhibitor of RNA polymerase I (Pol I), specifically targeting the large catalytic subunit RPA194, demonstrating an inhibitionFormula:C23H22N4O2Colore e forma:SolidPeso molecolare:386.45Lamivudine, (+/-)-trans-
CAS:<p>Lamivudine, a drug for HIV-1 and HBV, inhibits reverse transcriptase and resembles zalcitabine.</p>Formula:C8H11N3O3SPurezza:98%Colore e forma:SolidPeso molecolare:229.26HIV-1 inhibitor-8
HIV-1 inhibitor-8: potent oral NNRTI, low toxicity, IC50: 0.081 μM, effective on multiple strains, EC50: 4.44-54.5 nM.Formula:C25H21N5OSColore e forma:SolidPeso molecolare:439.537-APRA
CAS:7-APRA is a semisynthetic intermediate of the cephalosporin class of antibiotics. It exhibits antibacterial activity and is primarily used in the synthesis of other cephalosporin antibiotics, such as Cefaclor and Cefprozil.Formula:C10H12N2O3SPeso molecolare:240.28CB 30900
CAS:CB30900 is a novel and effective thymidylate synthase inhibitor.Formula:C31H32FN5O9Colore e forma:SolidPeso molecolare:637.61Jun13296
CAS:<p>Jun13296 is an orally active quinoline SARS-CoV-2 papain-like protease inhibitor (IC50 = 0.13 µM, Ki = 8.8 nM). It demonstrates potent inhibitory effects against SARS-CoV-2 variants and Nirmatrelvir-resistant mutants. Jun13296 reduces lung viral titers and prevents lung tissue damage in SARS-CoV-2 infection models.</p>Formula:C30H34N6OColore e forma:SolidPeso molecolare:494.631KKL-40
CAS:<p>KKL-40 is a small-molecule inhibitor that targets the trans-translation process, effectively suppressing methicillin-sensitive and resistant Staphylococcus aureus (S. aureus) and other Gram-positive pathogens, including vancomycin-resistant Enterococcus faecium, Bacillus subtilis, and Streptococcus pyogenes. It works in synergy with the human antimicrobial peptide LL-37 to inhibit S. aureus, but does not show synergistic effects with other antibiotics such as daptomycin, kanamycin, or erythromycin. KKL-40 inhibits trans-translation, an extreme form of recoding, while being non-toxic to HeLa cells.</p>Formula:C16H9F4N3O2Colore e forma:SolidPeso molecolare:351.255VPC-80051
CAS:<p>VPC-80051 is an hnRNP A1 splicing activity inhibitor that directly interacts with the hnRNP A1 RBD and reduces AR-V7 messenger levels in the 22Rv1 CRPC cell line. VPC-80051 is applicable in prostate cancer research.</p>Formula:C16H13F2N3OColore e forma:SolidPeso molecolare:301.291Atramycin A
CAS:<p>Atramycin A is an anthraquinone antibiotic with antitumor properties.</p>Formula:C25H24O9Colore e forma:SolidPeso molecolare:468.453BMS-818251
CAS:BMS-818251 is a potent small-molecule inhibitor that targets HIV-1 entry, with an EC50 value of 0.019 nM. It exhibits over 10 times greater efficacy on the cross-subtype panels of the 208-HIV-1 strain compared to BMS-626529. BMS-818251 enhances potency through interactions with gp120 residues in the conserved β20-β21 hairpin.Formula:C29H26N6O5SColore e forma:SolidPeso molecolare:570.619YKL-04-085
CAS:<p>YKL-04-085 inhibits viral translation effectively, with strong antiviral action at much lower doses than those affecting host-cell growth.</p>Formula:C30H29N5O2Colore e forma:SolidPeso molecolare:491.6GRL-190-21
CAS:<p>GRL-190-21 (compound 5e), an inhibitor of SARS-Cov-2-Mpro, shows potent antiviral activity, with a K_i of 0.04 nM and an EC_50 of 0.26 μM in VeroE6 cells. It significantly reduces the infectivity, replication, and cytopathic effect of SARS-CoV-2 without notable toxicity [1].</p>Formula:C24H34F3N5O4Colore e forma:SolidPeso molecolare:513.55MsbA-IN-5
MsbA-IN-5 (compound 40) is a potent and highly selective inhibitor of MsbA (IC50: 2 nM). MsbA-IN-5 can be used in Gram-negative studies.Formula:C23H19Cl2N5OColore e forma:SolidPeso molecolare:452.34GHP-88309
CAS:<p>GHP-88309 is an orally active, broad-spectrum anti-paramyxovirus agent that targets viral polymerase, interrupting viral RNA synthesis. It effectively inhibits respiratory syncytial virus (RSV), measles virus (MeV), and canine distemper virus (CDV) with an EC50 of 0.06-1.2 μM. In mouse models, GHP-88309 demonstrates significant anti-infective activity.</p>Formula:C16H11FN2OColore e forma:SolidPeso molecolare:266.27
