Microbiologia/Virologia
Gli inibitori in microbiologia e virologia sono composti che bersagliano microrganismi, inclusi batteri, virus e funghi, interrompendo la loro crescita, replicazione o sopravvivenza. Questi inibitori sono essenziali per studiare la patogenesi microbica, comprendere i meccanismi di resistenza e sviluppare nuove terapie antimicrobiche e antivirali. Gli inibitori in questa categoria vengono utilizzati per combattere le malattie infettive, esplorare l'ecologia microbica e studiare le interazioni ospite-patogeno. Presso CymitQuimica, offriamo un'ampia selezione di inibitori di alta qualità in microbiologia e virologia per supportare la tua ricerca in malattie infettive, microbiologia e virologia.
Sottocategorie di "Microbiologia/Virologia"
- Antibatterico(2.957 prodotti)
- Antibiotico(920 prodotti)
- Antinfettivo(23 prodotti)
- DHFR(33 prodotti)
- Sintesi del DNA/RNA(708 prodotti)
- HBV(176 prodotti)
- Proteasi HIV(449 prodotti)
- HSV(91 prodotti)
- Integrasi(2 prodotti)
- Ribosoma(13 prodotti)
Mostrare 2 più sottocategorie
Trovati 5842 prodotti di "Microbiologia/Virologia"
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ONO-5334
CAS:<p>ONO-5334: selective cathepsin K inhibitor, potential for osteoporosis study; Ki: 0.10 nM (human), 0.049 nM (rabbit), 0.85 nM (rat).</p>Formula:C21H34N4O4SPurezza:98.22% - 99.60%Colore e forma:SolidPeso molecolare:438.58Benzisothiazolone
CAS:<p>Benzisothiazolone is an isothiazolinone fungicide that demonstrates growth inhibitory activity against Escherichia coli ATCC 8739 and yeast NCYC 1354. It is utilized in studies investigating growth inhibition models.</p>Formula:C7H5NOSColore e forma:SolidPeso molecolare:151.19SP-471
<p>SP-471 is a potent inhibitor of dengue virus (DENV) protease (IC50: 18 μM) and inhibits the inter- and intramolecular protease processes of DENV.</p>Formula:C33H26BrN5Colore e forma:SolidPeso molecolare:572.5RSV-IN-7
CAS:<p>RSV-IN-7 (example 253) is a RSV inhibitor ( EC 50 : < 0.4 μΜ) .</p>Formula:C27H22F3N7O3Colore e forma:SolidPeso molecolare:549.50Teslexivir
CAS:<p>Teslexivir is a topical antiviral agent that is an effective and selective inhibitor of the interaction between two essential viral proteins, E1 and E2.</p>Formula:C35H36BrN3O4Purezza:98%Colore e forma:SolidPeso molecolare:642.58EBOV-GP-IN-1
<p>EBOV-GP-IN-1 (Compound 28) is a potent inhibitor of Ebola entry, acting on the Ebola virus envelope glycoprotein (EBOV-GP) (IC50: 0.05 μM).</p>Formula:C25H40ClN3O2Colore e forma:SolidPeso molecolare:450.06Lentiginosine
CAS:<p>Lentiginosine is a selective amyloglucosidase inhibitor.</p>Formula:C8H15NO2Colore e forma:SolidPeso molecolare:157.21MsbA-IN-5
<p>MsbA-IN-5 (compound 40) is a potent and highly selective inhibitor of MsbA (IC50: 2 nM). MsbA-IN-5 can be used in Gram-negative studies.</p>Formula:C23H19Cl2N5OColore e forma:SolidPeso molecolare:452.34AG-7404
CAS:<p>AG-7404: strong protease inhibitor, fights poliovirus, EC50 0.080-0.674 μM, effective on V-073-resistant strains.</p>Formula:C26H29N5O7Colore e forma:SolidPeso molecolare:523.54Antitubercular agent-29
<p>Compound 6xa inhibits drug-resistant tuberculosis with MICs 0.03 μg/mL for DS-Mtb and 0.03-0.06 for DR-Mtb, SI>40 for Vero cells.</p>Formula:C20H12ClN3O5Colore e forma:SolidPeso molecolare:409.78Isopyrazam
CAS:Isopyrazam, a plant protection product, exhibits potent antifungal activity. When applied to crops, it effectively inhibits the growth of various plant pathogenic fungi, significantly enhancing both the yield and quality of the crops. This compound demonstrates exceptional disease resistance capabilities in agricultural applications.Formula:C20H23F2N3OColore e forma:SolidPeso molecolare:359.41Antibiofilm agent-14
CAS:<p>Antibiofilm agent-14 (compound 11) functions as an antibiofilm agent. It exhibits antifungal activity against C.albicans SC5314, with a minimum inhibitory concentration (MIC) of 50 μM.</p>Formula:C26H30ClN3OColore e forma:SolidPeso molecolare:435.989BAR-072
CAS:<p>BAR-072 is a small molecule inhibitor targeting TraE with a KD value of 2.7 µM. It significantly suppresses the transfer of the antibiotic resistance-associated plasmid pKM101. BAR-072 holds promise as a candidate molecule for research in disease areas related to infection and resistance control, by inhibiting the spread of bacterial resistance genes.</p>Formula:C18H13N3O6Colore e forma:SolidPeso molecolare:367.312E6-272
CAS:<p>E6-272, an inhibitor of HPV 16, induced early and late apoptosis in HPV16-positive cervical cancer cells and inhibited the proliferation of SiHa and CaSki.</p>Formula:C26H28N2OPurezza:99.82%Colore e forma:SolidPeso molecolare:384.51Palmitanilide
CAS:<p>Palmitanilide (Palmitic acid anilide) is an antimicrobial agent effective against Gram-positive bacteria. It can electrostatically bind to components of the cell wall of Gram-positive bacteria (such as Bacillus cereus), altering the membrane structure and affecting normal cellular functions. Palmitanilide shows potential for research into infections caused by Gram-positive bacteria.</p>Formula:C22H37NOColore e forma:SolidPeso molecolare:331.535Antibacterial agent 112
<p>Compound 112: Powerful antibacterial, MIC 1250 μM against B. subtilis, E. coli, E. faecalis, S. typhimurium, S. aureus; also an HIV-1 antibody.</p>Formula:C35H23N5O5Colore e forma:SolidPeso molecolare:593.59Antiviral agent 15
<p>Compound 15f, a Clofazimine derivative, inhibits rabies (EC50: 1.45 μM) and SARS-CoV-2 (EC50: 14.6 μM).</p>Formula:C27H24FN5OColore e forma:SolidPeso molecolare:453.51Enantiomer of Sofosbuvir
<p>Inactive enantiomer of Sofosbuvir, used for chronic hepatitis C; lacks reported biological activity.</p>Formula:C22H29FN3O9PPurezza:98%Colore e forma:SolidPeso molecolare:529.45Antibacterial agent 80
<p>Antibacterial agent 80 (compound 20) has antibacterial activity [1].</p>Formula:C14H21N3S2Colore e forma:SolidPeso molecolare:295.47EBOV-IN-10
CAS:<p>EBOV-IN-10 is an orally active inhibitor of the Ebola virus (EBOV) with an EC50 value of 0.19 μM.</p>Formula:C22H22N2O2SColore e forma:SolidPeso molecolare:378.49HIV-1 inhibitor-18
<p>HIV-1 inhibitor-18 blocks HIV-1 capsid, effective on NL4-3 strain (EC50: 5.14 μM), slightly toxic (MT-4CC50>9.51).</p>Formula:C27H31N3O6SColore e forma:SolidPeso molecolare:525.62Polθ-IN-7
CAS:<p>Polθ-IN-7 (example 12) is an inhibitor of DNA polymerase θ (Polθ) with a Ki of 1.27 nM.</p>Formula:C28H35F3N6O2Colore e forma:SolidPeso molecolare:544.612Antitubercular agent-15
<p>Antitubercular agent-15 (5n): low toxicity, fights M. tuberculosis strains; MIC90 values range 0.73-18.8 μg/mL.</p>Formula:C21H29FN2Colore e forma:SolidPeso molecolare:328.47MtMetAP1-IN-1
<p>MtMetAP1-IN-1 is an inhibitor of methionine aminopeptidase 1 ( MetAP1 ). MtMetAP1-IN-1 shows antimycobacterial activity.</p>Formula:C15H10BrN5O2SColore e forma:SolidPeso molecolare:404.24Eravacycline
CAS:<p>Eravacycline (TP-434) is a potent and broad-spectrum antibacterial agent.</p>Formula:C27H31FN4O8Purezza:97.46%Colore e forma:SolidPeso molecolare:558.56ALG-000184
CAS:<p>ALG-000184, a prodrug of the potent HBV capsid assembly modulator ALG-001075, shows potential for use in HBV infection research.</p>Formula:C23H20FN4Na2O8PColore e forma:SolidPeso molecolare:576.379NS2B/NS3-IN-4
CAS:<p>Compound 34e inhibits DENV2/ZIKV proteases; IC50: 0.69 µM (DENV2), 1.04 µM (ZIKV).</p>Formula:C15H11NO4Colore e forma:SolidPeso molecolare:269.25Antibiotic U 44590
CAS:<p>5,6-Dihydro-5-azathymidine exhibits activity against both Gram-positive and Gram-negative bacteria, as well as DNA viruses.</p>Formula:C9H15N3O5Colore e forma:SolidPeso molecolare:245.23AAA-10 formic
<p>AAA-10 formic is an orally active inhibitor of intestinal bacterial bile salt hydrolase (BSH) against B.</p>Formula:C26H43FO7SColore e forma:SolidPeso molecolare:518.68DNDI-8219
CAS:<p>DNDI-8219 is an antitubercular agent. It has potent antileishmanial effects.</p>Formula:C13H10F3N3O5Colore e forma:SolidPeso molecolare:345.23L-697639
CAS:<p>L-697639 inhibits of HIV-1 reverse transcriptase and HIV-1 replication.</p>Formula:C18H21N3O2Colore e forma:SolidPeso molecolare:311.38Ep vinyl quinidine
CAS:<p>3-Epiquinine is a Quinidine stereoisomer, used in malaria, antiarrhythmic, inhibits P450db, and blocks K+ channels, IC50: 19.9 μM.</p>Formula:C20H24N2O2Colore e forma:SolidPeso molecolare:324.42Ciluprevir
CAS:<p>Ciluprevir is a selective HCV NS3 protease inhibitor, effective against non-genotype-1 HCV; less potent for genotypes 2/3.</p>Formula:C40H50N6O8SPurezza:98%Colore e forma:SolidPeso molecolare:774.93LN-439A
CAS:<p>LN-439A (compound LN-439A) is a novel BAP1 inhibitor that suppresses the growth of basal-like breast cancer by degrading KLF5.</p>Formula:C24H26FN3O4Colore e forma:SolidPeso molecolare:439.48Epolactaene
CAS:<p>Epolactaene: neuritogenic, inhibits mammalian DNA polymerases & human DNA topoisomerase II.</p>Formula:C21H27NO6Colore e forma:SolidPeso molecolare:389.44SARS-CoV-2 PLpro-IN-1
CAS:<p>SARS-CoV-2 PLpro-IN-1 (Compound 85) is a non-covalent competitive inhibitor of SARS-CoV-2 PLpro with an IC50 value of 15.06 μM and a Ki value of 22.93 μM. It inhibits the proliferation of Vero cells, exhibiting an IC50 of 7.47 μM.</p>Formula:C18H19N5OColore e forma:SolidPeso molecolare:321.376CB 30900
CAS:<p>CB30900 is a novel and effective thymidylate synthase inhibitor.</p>Formula:C31H32FN5O9Colore e forma:SolidPeso molecolare:637.61Amicoumacin A
CAS:<p>Amicoumacin A has antibacterial activity. It also strongly suppresses inflammatory and ulcer activity.</p>Formula:C20H29N3O7Purezza:98%Colore e forma:SolidPeso molecolare:423.46Integrase-LEDGF/p75 allosteric inhibitor 1
CAS:<p>Oral HIV-1 allosteric integrase inhibitor, blocks DNA integration, antiviral, potent against NL432 (EC50: 3.9 nM).</p>Formula:C33H41NO6SColore e forma:SolidPeso molecolare:579.75CRS-3123
CAS:<p>CRS-3123, a methionyl-tRNA synthetase inhibitor, is used potentially for the treatment of enteric infections.</p>Formula:C19H19Br2N3O2SPurezza:98%Colore e forma:SolidPeso molecolare:513.25Urease-IN-1
<p>Urease -IN-1 is a urease inhibitor (IC50: 2.21±0.45 μM).</p>Formula:C17H12BrFN4O2SColore e forma:SolidPeso molecolare:435.278-Deazafolic acid
CAS:<p>8-Deazafolic acid inhibits folate-dependent bacteria S. faecium & L. casei, and fights lymphoid leukemia L1210 in mice.</p>Formula:C20H20N6O6Purezza:98%Colore e forma:SolidPeso molecolare:440.41YKL-04-085
CAS:<p>YKL-04-085 inhibits viral translation effectively, with strong antiviral action at much lower doses than those affecting host-cell growth.</p>Formula:C30H29N5O2Colore e forma:SolidPeso molecolare:491.6NBTIs-IN-4
<p>NBTIs-IN-4, a broad-spectrum Gram-positive antibacterial, inhibits DNA rotamases/topoisomerase IV, with low resistance.</p>Formula:C22H24FN5O5SColore e forma:SolidPeso molecolare:489.52PF 03709270
CAS:<p>PF 03709270 is an oral prodrug of sulopenem with broad-spectrum antibacterial effects on gram-positive and gram-negative bacteria.</p>Formula:C19H27NO7S3Purezza:98%Colore e forma:SolidPeso molecolare:477.61NSC 641396
CAS:<p>NSC 641396 is a ribonucleotide reductase (RNR) inhibitor with an IC50 value of 1.2 μM. Additionally, it acts as an inhibitor of protein arginine N-methyltransferase 9 (PRMT9) and exhibits antitumor properties.</p>Formula:C18H13NO3Colore e forma:SolidPeso molecolare:291.301(R)-CSN5i-3
CAS:<p>(R)-CSN5i-3 is CSN5i-3 of the R configuration.</p>Formula:C28H29F2N5O2Purezza:99.76% - 99.97%Colore e forma:SolidPeso molecolare:505.56MsbA-IN-1
<p>MsbA-IN-1: Potent MsbA inhibitor (IC50: 4 nM), anti-E. coli (MIC: 79 μM), penetrates Gram-negative bacteria.</p>Formula:C23H18Cl2FNO3Colore e forma:SolidPeso molecolare:446.3Antifungal agent 40
<p>Antifungal agent 40 blocks C. albicans CYP51 in pocket II, hindering lanosterol demethylase and biofilm growth.</p>Formula:C22H20Cl2N4SeColore e forma:SolidPeso molecolare:490.29RmlA-IN-2
<p>RmlA-IN-2: Strong RmlA blocker, hinders l-rhamnose synthesis & alters bacterial wall permeability (IC50: 0.303 μM).</p>Formula:C22H26BrN5O4SColore e forma:SolidPeso molecolare:536.44Chitin synthase inhibitor 11
<p>Potent CHS inhibitor with an IC50 of 0.10 mM; exhibits broad-spectrum antifungal properties.</p>Formula:C24H24N4O8Colore e forma:SolidPeso molecolare:496.47PRRSV-IN-1
CAS:<p>PRRSV-IN-1 (Compound 4s) acts as an inhibitor of the nsp4 protease of PRRSV. It has an EC50 value of 0.45 μM against PRRSV, binds to the nsp4 protease with a Kd of 29.24 pM, and exhibits an IC50 value of 80.36 pM for nsp4 protease inhibition. PRRSV-IN-1 is applicable in antiviral infection research.</p>Formula:C19H18BrNO3Colore e forma:SolidPeso molecolare:388.255Chitin synthase inhibitor 7
<p>Compound 9c, a chitin synthase inhibitor, has an IC50 of 0.37 nM and is useful for studying fungal infections.</p>Formula:C24H25N3O5Colore e forma:SolidPeso molecolare:435.47Antitubercular agent-22
<p>Antitubercular agent-22 combats Candida albicans (MIC: 2.34 μg/ml) and M. tuberculosis (MIC: 2 μg/ml).</p>Formula:C24H28FN5O8Colore e forma:SolidPeso molecolare:533.51Fosmanogepix
CAS:<p>Fosmanogepix (APX001) is a broad-spectrum oral antifungal that targets Gwt1 enzyme, transforming into active APX001A in the body.</p>Formula:C22H21N4O6PPurezza:98%Colore e forma:SolidPeso molecolare:468.40FtsZ-IN-4
<p>FtsZ-IN-4 is an oral FtsZ inhibitor with strong antibacterial effects and good drug traits, low toxicity (CC50 >20μg/mL).</p>Formula:C21H16ClF2NO2Colore e forma:SolidPeso molecolare:387.81Antifungal agent 27
<p>Antifungal agent 27 shows moderate action against MRSA, weak against C. albicans, with MICs of 8 μg/mL and 32 μg/mL, respectively.</p>Formula:C18H23N5OSColore e forma:SolidPeso molecolare:357.477-Hydroxytropolone
CAS:<p>7-Hydroxytropolone (3-Hydroxytropolone) is an antibiotic that exhibits activity against Gram-positive and Gram-negative bacteria, as well as yeasts and fungi. It also functions as an inhibitor of 2''-O-adenylate transferase.</p>Formula:C7H6O3Colore e forma:SolidPeso molecolare:138.12Neuraminidase-IN-11
<p>Neuraminidase-IN-11 (15e) inhibits H1N1 (IC50: 4.7nM), H5N1 (8.46nM), H5N8 viruses (1.5nM) selectively & potently.</p>Colore e forma:SolidAntifungal agent 28
<p>Antifungal 28 disrupts Candida, hits fluconazole-resistant strains, and inhibits biofilms.</p>Formula:C22H29N5OSColore e forma:SolidPeso molecolare:411.56MCB-3681
CAS:<p>MCB-3681, active against gram-positive bacterium, is the antibacterial Oxaquin's active substance.</p>Formula:C31H32F2N4O8Colore e forma:SolidPeso molecolare:626.6Cap-dependent endonuclease-IN-25
CAS:<p>Cap-dependent endonuclease-IN-25 is a potent inhibitor of CEN, useful in studying Orthomyxoviridae viruses. (See WO2020075080A1, compound 4.)</p>Formula:C25H25N3O3Colore e forma:SolidPeso molecolare:415.48(E)-Cefodizime
CAS:<p>(E)-Cefodizime ((E)-THR-221) is an antibiotic that selectively binds to penicillin-binding proteins (PBPs), inhibiting bacterial cell wall synthesis, which results in its antibacterial activity. It holds potential for research into various bacterial infections, including the prevention of preoperative infections.</p>Formula:C20H20N6O7S4Colore e forma:SolidPeso molecolare:584.669Secutrelvir
CAS:<p>Secutrelvir inhibits the 3CL protease (3CL protease), thereby exhibiting antiviral activity by preventing the replication of SARS-CoV-2.</p>Formula:C23H16Cl2F3N5O2Colore e forma:SolidPeso molecolare:522.307WR-27653
CAS:<p>WR-27653 (RC-12), a derivative of Catechol, demonstrates significant activity against hypnozoites in the Plasmodium cynomolgi-Rhesus monkey (Macaca mulatta) model, which is considered the gold standard. Additionally, WR-27653 exhibits antimalarial properties.</p>Formula:C20H36BrN3O2Colore e forma:SolidPeso molecolare:430.423SARS-CoV-2 Mpro-IN-44
CAS:<p>SARS-CoV-2 Mpro-IN-44 (Compound 25) is a broad-spectrum inhibitor of the main protease (Mpro) for coronaviruses. It exhibits inhibitory activity against several high-risk coronaviruses, including SARS-CoV-2 and PEDV, with an IC50 of less than 0.6 μM. The broad inhibition of coronaviruses by SARS-CoV-2 Mpro-IN-44 is achieved through enhanced interaction with conserved sites of Mpro. This compound is a potential candidate for the development of antiviral drugs against coronaviruses.</p>Formula:C29H19Cl2FN8O4SColore e forma:SolidPeso molecolare:665.48MB076
CAS:MB076 is an innovative heterocyclic triazole designed with enhanced plasma stability. It effectively inhibits seven distinct Class C Acinetobacter-derived cephalosporinases (ADCs) β-lactamase variants with K i values less than 1 μM. Additionally, MB076 demonstrates a synergistic effect when combined with various cephalosporins to restore pBCSK(−) susceptibility [1].Formula:C9H12BN7O5S2Peso molecolare:373.18NBD-10007
CAS:NBD-10007 is an inhibitor of HIV-1 entry.Formula:C20H25ClN4O3SPurezza:98%Colore e forma:SolidPeso molecolare:436.96Omaciclovir
CAS:<p>Omaciclovir (ABT-091) is a herpesvirus herpesvirus replication inhibitor with antiviral activity that is used in the study of herpesvirus infections.</p>Formula:C10H15N5O3Purezza:99.46% - 99.46%Colore e forma:SolidPeso molecolare:253.26Ibafloxacine
CAS:<p>Ibafloxacine (R835) is a fluoroquinolone antibiotic that is used exclusively in veterinary applications and shows zero good bacteriostatic effect against</p>Formula:C15H14FNO3Purezza:97.67%Colore e forma:SolidPeso molecolare:275.27Saroaspidin B
CAS:<p>Saroaspidin B is a dimeric form of a biphenyl triphenol, characterized as an antibiotic compound.</p>Formula:C25H32O8Colore e forma:SolidPeso molecolare:460.52L 702007
CAS:<p>L 702007 is an inhibitor of HIV-1 reverse transcriptase.</p>Formula:C18H25N3O2Purezza:98%Colore e forma:SolidPeso molecolare:315.41APE1-IN-3
CAS:<p>APE1-IN-3 (Compound 1), an APE1 inhibitor, is utilized in cancer research.</p>Formula:C17H16O4Colore e forma:SolidPeso molecolare:284.312-Acetyl-2-decarboxamidotetracycline
CAS:<p>2-Acetyl-2-decarboxamidotetracycline is a tetracycline-class antibiotic. It exhibits a UV absorption spectrum similar to that of tetracycline or 5-oxytetracycline at concentrations above 300 mμ, characteristic of the BCD ring system.</p>Formula:C23H25NO8Colore e forma:SolidPeso molecolare:443.45Etofamide
CAS:<p>Etofamide, an antimicrobial agent, exhibits an IC50 of 5.96 mg/L against amoebae.</p>Formula:C19H20Cl2N2O5Colore e forma:SolidPeso molecolare:427.28HBV-IN-20
<p>HBV-IN-20 is a potent, orally active HBV inhibitor (EC50: 0.46 μM). HBV-IN-20 is a classical type II CpAM (core protein assembly regulator).</p>Colore e forma:SolidSaptomycin E
CAS:<p>Saptomycin E is an antitumor antibiotic.</p>Formula:C33H35NO9Colore e forma:SolidPeso molecolare:589.63Kikumycin A
CAS:<p>Kikumycin A, an antibiotic produced by Streptomyces, exhibits antimicrobial activity against both Gram-positive and Gram-negative bacteria. Additionally, it demonstrates antitrichomonal activity with a minimum inhibitory concentration (MIC) of 25 μg/mL against Trichomonas foetus.</p>Formula:C13H17N7O2Colore e forma:SolidPeso molecolare:303.32SARS-CoV-2 3CLpro-IN-28
CAS:<p>SARS-CoV-2 3CLpro-IN-28 (Compound 19) is an inhibitor of SARS-CoV-2 3CLpro, exhibiting an IC50 value of 0.018 μM.</p>Formula:C27H18Cl2N4O4Colore e forma:SolidPeso molecolare:533.362Rubropunctatin
CAS:<p>Rubropunctatin is a monascus pigment with very potent cancer cell proliferation inhibitory effects.</p>Formula:C21H23NO4Colore e forma:SolidPeso molecolare:353.41QPX7728 methoxy acetoxy methy ester
CAS:<p>QPX7728 methoxy acetoxy methy ester is an inhibitor of boronic acid β-lactamase.</p>Formula:C14H14BFO7Purezza:98%Colore e forma:SolidPeso molecolare:324.07Carumonam Sodium
CAS:<p>Carumonam Sodium is a monobactam, penicillin-binding protein inhibitor. It is used as antibacterials.</p>Formula:C12H12N6Na2O10S2Purezza:98%Colore e forma:SolidPeso molecolare:510.37GTSE1-IN-1
CAS:<p>GTSE1-IN-1 (compound Y18), an orally active GTSE1 inhibitor, exhibits notable anticancer properties. It effectively represses the proliferation of cancer cells by downregulating GTSE1 transcription and expression, which leads to DNA damage and promotes persistent cell cycle arrest and cellular senescence. Moreover, GTSE1-IN-1 substantially reduces the adhesion, migration, and invasion of colorectal cancer HCT116 cells and non-small cell lung cancer A549 cells in vitro.</p>Formula:C21H24FN7Colore e forma:SolidPeso molecolare:393.46Bilanafos
CAS:<p>Bilanafos is an agent of Anti-Bacterial.</p>Formula:C11H22N3O6PPurezza:98%Colore e forma:SolidPeso molecolare:323.28Ganaplacide hydrochloride
CAS:<p>Ganaplacide hydrochloride (KAF156 HCl) is an orally administered imidazopyrimidine antimalarial agent that inhibits Plasmodium PI4K activity.</p>Formula:C22H24ClF2N5OPurezza:93.97%Colore e forma:SoildPeso molecolare:447.91Anti-MRSA agent 2
CAS:<p>Anti-MRSA agent 2 inhibits MRSA at 0.098 μg/ml, with low toxicity and disrupts bacterial membranes and DNA.</p>Formula:C18H10Br2N2OColore e forma:SolidPeso molecolare:430.09Finafloxacin
CAS:<p>Finafloxacin is a pH-activated fluoroquinolone, most effective at pH 5.0-6.0, targeting bacterial topoisomerases, used for UTIs and H. pylori infections.</p>Formula:C20H19FN4O4Colore e forma:SolidPeso molecolare:398.3917,17-Ethylendioxyandrost-5-en-3β-ol
CAS:<p>17,17-Ethylendioxyandrost-5-en-3β-ol, with an EC 50 of 629 μM, acts as an inhibitor of HSV-1. This compound is applicable in research studies focusing on viral infections.</p>Formula:C21H32O3Colore e forma:SolidPeso molecolare:332.48Antifungal agent 11
<p>Antifungal agent 11 has a good antifungal effect.</p>Formula:C21H19F2N7O3S2Colore e forma:SolidPeso molecolare:519.55MTH1 activator-1
CAS:<p>MTH1 activator-1 is an MTH1 activator that enhances endogenous MTH1 activity and significantly reduces 8-oxo-dG levels in cellular DNA. It is useful for investigating the upregulation of oxidative damage repair in nucleotide pools and examining biological effects, as well as for studies aiming to delay or prevent tumorigenesis.</p>Formula:C29H23F3N4O2Colore e forma:SolidPeso molecolare:516.514MI-1851
CAS:<p>MI-1851 is a potent peptidomimetic inhibitor. MI-1851could prevent proteolytic processing of the S protein from SARSCoV-2 by endogenous furin in HEK293 cells.</p>Formula:C34H53N15O6Colore e forma:SolidPeso molecolare:767.88Antibacterial agent 82
<p>Antibacterial agent 82 (compound 7p) is an antibacterial agent [1].</p>Formula:C22H18N2O2Colore e forma:SolidPeso molecolare:342.39G247
<p>G247 inhibits MsbA by keeping NBDs apart, blocking ATPase activity.</p>Formula:C24H19Cl2FO3Colore e forma:SolidPeso molecolare:445.31HBV-IN-24
<p>HBV-IN-24 inhibits HBV DNA, HBsAg, HBeAg (EC50: 0.6, 0.6, 4.6 nM), and has antiviral properties with neurotoxicity mitigation.</p>Formula:C23H27NO6Colore e forma:SolidPeso molecolare:413.46HBV-IN-48
CAS:<p>HBV-IN-48, an HBV inhibitor, exhibits potent antiviral activity against HBV in HepDE19 cells, demonstrated by its EC 50 value of 0.005 μM. Additionally, it effectively reduces serum HBV DNA levels in mouse models of HBV infection.</p>Formula:C22H15F4N3O3Colore e forma:SolidPeso molecolare:445.37Cap-dependent endonuclease-IN-10
CAS:<p>Cap-dependent endonuclease-IN-10, with low toxicity & good stability, effectively inhibits flu viruses and shows promise against A, B, C types.</p>Formula:C25H18F2N4O5SColore e forma:SolidPeso molecolare:524.50KPC-2-IN-2
<p>KPC-2-IN-2 (6c) inhibits KPC-2 enzyme in Klebsiella pneumoniae (Ki 0.038 μM) and boosts cefotaxime in E. coli KPC-2.</p>Formula:C12H10BN3O2SColore e forma:SolidPeso molecolare:271.1DNA ligase-IN-2
CAS:<p>DNA ligase-IN-2 (compound 2) acts as a potent LigA inhibitor, effectively hindering the DNA-independent spontaneous adenylation activity of full-length LigA and the truncated enzyme LigA:AD with an IC50 of 29 nM. It also significantly suppresses the in vitro growth of Staphylococcus aureus, showing MIC values of 1 μg/mL for S. aureus ATCC 29213 and S. aureus ATCC 700699, while the MIC for Escherichia coli (E. coli) ATCC 25922 is >64 μg/mL.</p>Formula:C13H8FN3O3Colore e forma:SolidPeso molecolare:273.219NDM-1 inhibitor-3
<p>NDM-1 inhibitor-3 is a New Delhi Metallo-β-lactamase-1 (NDM-1) inhibitor (Ki : 4 μM) widely found in nature and is associated with antibiotic resistance.</p>Formula:C16H12O4Purezza:98.66%Colore e forma:SolidPeso molecolare:268.26RAD51-IN-6
CAS:<p>RAD51-IN-6, a potent RAD51 gene inhibitor, may help research mitochondrial disorders. (WO2021164746A1, cmpd 23)</p>Formula:C27H40N3O5PSColore e forma:SolidPeso molecolare:549.66GS-9822
CAS:<p>GS-9822 is a new LEDGIN inhibitor targeting LEDGF/p75 to alter HIV integration, showing a block-and-lock effect in cells.</p>Formula:C36H39ClN4O4SColore e forma:SolidPeso molecolare:659.24GSK_WRN4
CAS:<p>GSK_WRN4 is a WRN helicase inhibitor with anti-cancer activity, inhibiting MSI tumor cell growth by inducing DNA double-strand breaks, useful in cancer research</p>Formula:C16H20N2O4SPurezza:99.95%Colore e forma:SolidPeso molecolare:336.41PKZ18
CAS:<p>PKZ18 is an antibiotic that inhibits bacterial growth with a MIC value of 32-64 μg/mL against most Gram-positive bacteria. It suppresses the in vivo transcription and translation of glycyl-tRNA synthetase mRNA. PKZ18 selectively targets stem I specifier loops in Gram-positive bacteria, directly reducing T-box transcription readthrough of associated genes. It prevents codon-anticodon pairing necessary for tRNA binding and is less likely to induce resistance.</p>Formula:C22H26N2O3SColore e forma:SolidPeso molecolare:398.518PLpro-IN-6
CAS:<p>PLpro-IN-6 (compound 6) serves as an inhibitor for the papain-like protease (PLpro), demonstrating potent activity with an IC 50 of 0.019 μM against the SARS-CoV-2 PLpro enzyme.</p>Formula:C29H30N6OColore e forma:SolidPeso molecolare:478.59Valopicitabine dihydrochloride
CAS:<p>Valopicitabine, a NS5B inhibitor, is used potentially for the treatment of HCV infection.</p>Formula:C15H25ClN4O6Colore e forma:SolidPeso molecolare:392.843HKT-IN-1
CAS:<p>3HKT-IN-1 (Compound 17122279) is an inhibitor of Anopheles gambiae 3-hydroxykynurenine transaminase (3HKT) and is utilized in malaria research.</p>Formula:C12H11BrN2O3Colore e forma:SolidPeso molecolare:311.131MsbA-IN-3
<p>MsbA-IN-3 is a potent and highly selective MsbA inhibitor (IC50: 2 nM). MsbA-IN-3 inhibits Escherichia coli activity (MIC: 35 μM).</p>Formula:C24H22Cl2N2O4SColore e forma:SolidPeso molecolare:505.41Tuberculosis inhibitor 4
<p>TB inhibitor 4, a spirothiazolidinone from mandelic acid, blocks 98% of M. tuberculosis H37Rv under 6 μg/mL.</p>Formula:C23H26N2O3SColore e forma:SolidPeso molecolare:410.533-Deazaguanosine
CAS:<p>3-Deazaguanosine (C3Guo) exhibits potent antiviral activity against SARS-CoV-2 with an EC50 of 1.14 μM and a CC50 greater than 200 μM in Vero E6 cells. It has the potential to prevent COVID-19.</p>Formula:C11H14N4O5Colore e forma:SolidPeso molecolare:282.25Furametpyr
CAS:<p>Furametpyr is a kind of low toxicity pesticides used to control plant diseases caused by various pathogenic microorganisms.</p>Formula:C17H20ClN3O2Purezza:98%Colore e forma:SolidPeso molecolare:333.81Antibacterial agent 63
CAS:<p>Aztreonam-siderophore conjugate 63 is an antibacterial agent that exhibits efficacy against Gram-negative bacteria through the linkage of aztreonam to a</p>Formula:C35H43N9O14S2Colore e forma:SolidPeso molecolare:877.9GC373
CAS:<p>GC373, an effective inhibitor of the SARS-CoV-2 M pro, impedes virus replication, exhibiting an inhibition concentration (IC 50) of 0.4 μM. This compound is valuable for use in anti-COVID-19 research.</p>Formula:C21H29N3O5Colore e forma:SolidPeso molecolare:403.47ZK-806450
CAS:<p>ZK-806450 is a compound with antiviral properties. It exhibits high binding potential to the allosteric site of the SARS-CoV-2 3CL protease and is capable of specific and stable interaction with the GAG site of the dengue virus envelope protein.</p>Formula:C31H31N5OColore e forma:SolidPeso molecolare:489.611Antileishmanial agent-6
<p>Antileishmanial agent-6: potent against Leishmania donovani, IC50 0.54μM; cytotoxic IC50 10.2μM.</p>Formula:C24H26O8Colore e forma:SolidPeso molecolare:442.46Cyclophilin inhibitor 1
CAS:<p>Cyclophilin inhibitor 1: orally available, Kd 5 nM, potent against HCV, EC50 for HCV 2a is 98 nM.</p>Formula:C31H39N5O7Purezza:98%Colore e forma:SolidPeso molecolare:593.67PLP_Snyder530
<p>PLP_Snyder530, a potent PL pro inhibitor, halts SARS-CoV-2 by triggering protease conformation changes.</p>Formula:C24H24N2O2Colore e forma:SolidPeso molecolare:372.46Antibacterial agent 90
<p>Antibacterial agent 90 (6n), a pleuromutilin derivative, targets Gram-positive pathogens and Mycoplasma pneumoniae.</p>Formula:C30H42N2O6Colore e forma:SolidPeso molecolare:526.66Antibacterial agent 88
<p>Antibacterial agent 88 is an effective antibacterial agent against B. subtilis (MIC: 4 μg/ml) with MIC values of ≤0.0156 μg/mL for MRSA, MRSE and S. aureus.</p>Formula:C31H44N2O6SColore e forma:SolidPeso molecolare:572.76Squalamine lactate
CAS:<p>Squalamine lactate is an aminosterol compound discovered in the tissues of the dogfish shark, with antimicrobial activity.</p>Formula:C37H71N3O8SPurezza:98%Colore e forma:SolidPeso molecolare:718.04LN002
CAS:<p>LN002 is an orally active inhibitor of Cryptosporidium oxidase, utilized for research in cryptosporidiosis.</p>Formula:C22H15N7Colore e forma:SolidPeso molecolare:377.40UNI418
CAS:<p>UNI418 is a dual inhibitor targeting PIKfyve and PIP5K1C, exhibiting antiviral activity against SARS-CoV-2 (EC50=1.4 μM). It inhibits the endocytosis of the virus mediated by ACE2 by suppressing PIP5K1C (IC50=60.1 nM; Kd=61 nM). Additionally, UNI418 impedes the entry of SARS-CoV-2 into host cells by inhibiting the proteolytic activation regulated by PIKfyve (Kd=0.78 nM).</p>Formula:C22H16N6Colore e forma:SolidPeso molecolare:364.40PLpro-IN-5
CAS:<p>PLpro-IN-5 (compound 21), serving as a PLPro protease inhibitor, boasts an IC50 of 91.14 nM. This compound exhibits a broad-spectrum antivirus efficacy, particularly effective against SARS-CoV, MERS-CoV, and SARS-CoV-2.</p>Formula:C26H33N3OColore e forma:SolidPeso molecolare:403.56Anti-Trypanosoma cruzi agent-2
<p>Compd 3b: anti-trypanosomal, IC50 0.51 μM (NINOA), 3.06 μM (INC-5), also combats T. gondii.</p>Formula:C17H10ClNO5Colore e forma:SolidPeso molecolare:343.72Anti-MRSA agent 6
<p>Anti-MRSA agent 6 (compound 3q6) is a potent anti-methicillin-resistant Staphylococcus aureus (anti-MRSA) agent with low cytoxicity for MCF-7, A549 cells [1].</p>Formula:C16H11F2N3Colore e forma:SolidPeso molecolare:283.28Neocryptolepine-Cl
CAS:<p>Neocryptolepine-Cl (compound Z24) is an inhibitor of Bcthi4, demonstrating excellent antifungal activity against B. cinerea, with an EC50 value of 0.56 μg/mL.</p>Formula:C16H11ClN2Colore e forma:SolidPeso molecolare:266.725Antifungal agent 43
<p>Antifungal agent 43 inhibits biofilms with low toxicity to human cancer cells.</p>Formula:C24H26N4Se2Colore e forma:SolidPeso molecolare:528.41trans-Clopenthixol
CAS:<p>Trans-Clopenthixol ((E)-Clopenthixol) is an antibiotic without any sedative properties. It can be used in vitro to inhibit Pseudomonas aeruginosa and Plasmodium falciparum.</p>Formula:C22H25ClN2OSColore e forma:SolidPeso molecolare:400.9652-CEES
CAS:<p>2-CEES is a mustard gas analogue that only forms DNA monoadducts. It induces centromere amplification in both human and mouse cells and can lead to chromosome instability.</p>Formula:C4H9ClSColore e forma:SolidPeso molecolare:124.632ATIC-IN-2
CAS:<p>ATIC-IN-2 (Compound 1) is a competitive inhibitor of the bifunctional enzyme AICAR Tfase/IMPCH (ATIC), binding to inosine monophosphate cyclohydrolase (IMPCH) with a Ki of 0.13 μM.</p>Formula:C4H4N4O3SColore e forma:SolidPeso molecolare:188.165Piperacillin hydrate
CAS:<p>Piperacillin hydrate is a semisynthetic broad-spectrum β-lactam antibiotic. It exhibits potent bactericidal activity against Gram-negative bacteria and some Gram-positive bacteria by targeting penicillin-binding proteins. Piperacillin hydrate is frequently combined with the β-lactamase inhibitor Tazobactam for enhanced efficacy.</p>Formula:C23H29N5O8SColore e forma:SolidPeso molecolare:535.57Anti-Trypanosoma cruzi agent-1
<p>Anti-Trypanosoma cruzi agent-1 (Compd E5) has a potent anti-Toxoplasma effect.</p>Formula:C23H29N3O5Colore e forma:SolidPeso molecolare:427.49MDL-860
CAS:<p>MDL-860 is a broad-spectrum antiviral compound targeting small RNA viruses and exhibits low cytotoxicity to human cells. MDL-860 is useful for research into viral infections.</p>Formula:C13H6Cl2N2O3Colore e forma:SolidPeso molecolare:309.104Saphenamycin
CAS:<p>Saphenamycin is an antibiotic from a strain of Streptomyces.</p>Formula:C23H18N2O5Purezza:98%Colore e forma:SolidPeso molecolare:402.40ZG297
CAS:<p>ZG297 is an agonist of Staphylococcus aureus ClpP (SaClpP) with an EC50 of 0.26 μM. It degrades SaFtsZ and inhibits bacterial cell division, exhibiting antistaphylococcal activity by inhibiting S. aureus 8325-4 and MRSA strains, with a MIC range of 0.063-256 μg/mL. In mouse models, ZG297 demonstrates anti-infective properties.</p>Formula:C31H35F3N4O3Colore e forma:SolidPeso molecolare:568.63RSV-IN-5
CAS:<p>RSV-IN-5: Dual inhibitor for RSV fusion proteins, effective on wild-type A2 and D486N mutant with EC50s of 2.0 nM & 8.1 nM. Potent anti-RSV.</p>Formula:C28H37N7O2Colore e forma:SolidPeso molecolare:503.64PCNA-IN-1
CAS:<p>PCNA-IN-1 (Compound 11) is an inhibitor of the PCNA/PIP-box interaction, with an IC50 greater than 50 μM. It is applicable in cancer research.</p>Formula:C19H18I3NO3Colore e forma:SolidPeso molecolare:689.065LolCDE-IN-2
CAS:<p>LolCDE-IN-2 is a potent Lol protein (LolCDE) inhibitor. LolCDE-IN-2 shows antibacterial activity with a MIC of 2 μg/ml against E. coli MG1655 [1].</p>Formula:C22H17N5OPurezza:98%Colore e forma:SolidPeso molecolare:367.40Doxazosin impurity 12
CAS:<p>Doxazosin impurity 12 acts as an inhibitor of CTX-M β-lactamase (Beta-lactamase) with a Ki value of 0.7 mM against CTX-M.</p>Formula:C10H6O5SColore e forma:SolidPeso molecolare:238.217Anti-MRSA agent 27
CAS:<p>Anti-MRSA agent 27 (compound 4a) is a potent antimicrobial agent against methicillin-resistant Staphylococcus aureus (MRSA) with a minimum inhibitory concentration (MIC) of 0.0975 μmol/L. It effectively disrupts MRSA biofilms and inhibits the production of hemolysins.</p>Formula:C15H10F3N3OSColore e forma:SolidPeso molecolare:337.32A25822B
CAS:<p>A25822B is an antifungal agent.</p>Formula:C28H45NOPurezza:98%Colore e forma:SolidPeso molecolare:411.66β-Glucuronidase-IN-2
<p>β-Glucuronidase-IN-2 is a potent inhibitor of E.</p>Formula:C21H17Cl3O7Colore e forma:SolidPeso molecolare:487.71Chitin synthase inhibitor 6
<p>Compound 9b inhibits CHS with an IC50 of 0.21 mM; it's a broad-spectrum antifungal, effective against resistant strains.</p>Formula:C24H25N3O6Colore e forma:SolidPeso molecolare:451.47Anti-infective agent 10
CAS:<p>Anti-infective agent 10 (Compound Example 30) is an ns5b polymerase inhibitor that functions as an anti-HCV agent.</p>Formula:C26H25N3O7SColore e forma:SolidPeso molecolare:523.56Antibacterial agent 66
<p>Compound 6q, a trifluoromethylpyridine oxadiazole, targets Xanthomonas oryzae with EC50 of 7.2 μg/mL.</p>Formula:C17H10ClF6N3O2SColore e forma:SolidPeso molecolare:469.79(Rac)-Plevitrexed
CAS:<p>(Rac)-Plevitrexed is a racemate of Plevitrexed. Plevitrexed is an orally active and potent inhibitor of thymidylate synthase (TS).</p>Formula:C26H25FN8O4Purezza:98%Colore e forma:SolidPeso molecolare:532.53Cefoxazole
CAS:<p>Cefoxazole is a β-lactam antibiotic featuring an isoxazole structure, known for its antibacterial activity. It can be utilized in the study of infectious diseases.</p>Formula:C21H18ClN3O7SColore e forma:SolidPeso molecolare:491.902Telinavir
CAS:<p>Telinavir (SC-52151) is a potent and selective inhibitor of HIV protease. It effectively inhibits both HIV-1 and HIV-2, as well as lymphotropic, monocytotropic strains, and wild isolates of simian immunodeficiency viruses, with an EC50 of 26 ng/mL (43 nM). Telinavir shows high protein binding in human plasma and a low distribution rate in red blood cells.</p>Formula:C33H44N6O5Colore e forma:SolidPeso molecolare:604.74Antimalarial agent 2
<p>Antimalarial agent 2 is an orally active, novel antimalarial agent that exhibits rapid in vitro killing effects.</p>Formula:C27H25N3O5Colore e forma:SolidPeso molecolare:471.5HIV-1 inhibitor-14
<p>HIV-1 inhibitor-14: potent, broad HIV-1 RT inhibitor. IC50=0.14μM. Effective against wild-type and resistant strains, EC50=5.79-28.3nM.</p>Formula:C29H32N6O4SColore e forma:SolidPeso molecolare:560.67Antibacterial agent 279
CAS:<p>Antibacterialagent 279 (compound A12) is an effective antibacterial agent. It inhibits the SOS response of Pseudomonas aeruginosa.</p>Formula:C9H11NO2SColore e forma:SolidPeso molecolare:197.25PqsR-IN-2
<p>PqsR-IN-2, potent PqsR inhibitor, curbs Pseudomonas aeruginosa communication, reduces pyocyanin, with low toxicity.</p>Formula:C18H20ClN3OSColore e forma:SolidPeso molecolare:361.89Fenbenicillin potassium
CAS:<p>Fenbenicillin (Phenbenicillin) potassium is a semi-synthetic penicillin with antibacterial spectrum activity.</p>Formula:C22H22KN2O5SColore e forma:SolidPeso molecolare:465.584Anticancer agent 36
<p>Compound 11: Sulfonylurea derivative, antimicrobial, anticancer; MIC 0.039-0.156 mg/mL; A549 IC50: 19.7 μg/mL, PC3 IC50: 11.9 μg/mL.</p>Formula:C21H17N3O3S2Colore e forma:SolidPeso molecolare:423.51SPR7
<p>SPR7 is a potent and selective rhodesain inhibitor (Ki: 0.51 nM). SPR7 exhibited antiparasitic effects against T. b. brucei (EC50: 1.65 μM).</p>Formula:C30H32ClN3O3Colore e forma:SolidPeso molecolare:518.05bc1 Complex-IN-1
CAS:<p>Bc1 Complex-IN-1 (compound 12g) is a potent inhibitor of the bc1 complex, demonstrating fungicidal properties against cucumber downy mildew (CDM).</p>Formula:C16H22N6O5S2Colore e forma:SolidPeso molecolare:442.513PFK-IN-1
CAS:<p>PFK-IN-1 (compound 1) is an inhibitor of 6-phosphofructo-1-kinase (PFK), demonstrating IC50 values of 0.41 and 0.23 μM against T. brucei and T. cruzi PFK, respectively, and an ED50 of 15.18 μg/mL for T. brucei. The compound has a half-life of 9.7 minutes in rat liver microsomes and 408 minutes in mouse liver microsomes.</p>Formula:C18H15Cl2N3O4SColore e forma:SolidPeso molecolare:440.3JPL
CAS:JPL is an InhA-cofactor-ligand 3FNG inhibitor and is used for the study of tuberculosis [1].Formula:C19H20Cl2O2Colore e forma:SolidPeso molecolare:351.27InhA-IN-7
CAS:<p>InhA-IN-7 (Compound 11), a derivative of Triclocan, shows inhibitory activity against enoyl-acyl carrier protein reductase (InhA) with an IC50 of 96 nM. It effectively inhibits the proliferation of both wildtype and mutant strains of Mycobacterium tuberculosis, exhibiting minimum inhibitory concentrations (MICs) ranging from 19 to 75 μM [1].</p>Formula:C17H18Cl2O2Colore e forma:SolidPeso molecolare:325.23Imidocarb dihydrochloride monohydrate
<p>Imidocarb dihydrochloride monohydrate is an effective antiprotozoal agent against the parasite B. bovis (IC50: 87 μg/ml).</p>Formula:C19H24Cl2N6O2Colore e forma:SolidPeso molecolare:439.34BPR3P0128
CAS:<p>BPR3P0128, a non-nucleoside RNA-dependent RNA polymerase (RdRp) inhibitor, is effective orally and can inhibit various SARS-CoV-2 variants. It exhibits EC 50 values of 0.62 µM for SARS-CoV-2 and 0.14 µM for HCoV-229E, demonstrating potent anti-pancoronavirus activity at submicromolar concentrations. Additionally, BPR3P0128 displays synergistic antiviral effects when used in combination with Remdesivir [1].</p>Formula:C22H18BrN3O2Colore e forma:SolidPeso molecolare:436.30TLR8 agonist 4
<p>TLR8 agonist 4 inhibits wild-type and lamivudine/entecavir-resistant HBV; IC50: 0.15 μM and 0.10 μM.</p>Formula:C28H27N5O5SColore e forma:SolidPeso molecolare:545.61Metallo-β-lactamase-IN-14
CAS:<p>Metallo-β-lactamase-IN-14 (Compound 17e) serves as an inhibitor of Metallo-β-Lactamase, displaying inhibitory activity against VIM-1 and VIM-2. This compound also exhibits antibacterial effects on Gram-negative (GN) bacteria and P. aeruginosa [1].</p>Formula:C20H22N8O2S2Colore e forma:SolidPeso molecolare:470.57Alpibectir
CAS:<p>Alpibectir has antibacterial activity [1].</p>Formula:C12H14F6N2O2Colore e forma:SolidPeso molecolare:332.24SAG-524
CAS:<p>SAG-524 is a powerful oral small molecule that inhibits HBV viral replication. In HepG2.2.15 cells, SAG-524 reduced HBV-DNA and HbsAg levels in the supernatant with IC₅₀ values of 0.92 nM and 1.4 nM, respectively [1].</p>Formula:C30H32ClN5O4SColore e forma:SolidPeso molecolare:594.12iPAF1C
CAS:<p>iPAF1C is a powerful inhibitor of the polymerase-associated factor 1 complex (PAF1C) and exhibits anti-HIV activity [1].</p>Formula:C27H26BrFN4OColore e forma:SolidPeso molecolare:521.42Antibacterial agent 68
<p>Antibacterial agent 68 targets drug-resistant E. coli at 0.007 mM with low cytotoxicity.</p>Formula:C26H25BrN4O7Colore e forma:SolidPeso molecolare:585.4Colistin adjuvant-1
<p>Colistin adjuvant-1, inhibits NF-κB (IC50: 0.209 μM), boosts mucin against gram-negative bacteria.</p>Formula:C16H7F9N2OColore e forma:SolidPeso molecolare:414.23Saussureamine C
CAS:<p>Saussureamine C is an inhibitor of H274Y and N294S mutants.</p>Formula:C19H26N2O5Colore e forma:SolidPeso molecolare:362.42HIV-1 inhibitor-13
<p>HIV-1 inhibitor-13: oral NNRTI, IC50=0.14μM for HIV-1 RT, effective on resistant strains (EC50=2.85-18nM).</p>Formula:C30H32N6O3Colore e forma:SolidPeso molecolare:524.61LpxA-IN-1
CAS:<p>LpxA-IN-1, a novel UDP-N-acetylglucosamine acyltransferase (LpxA) inhibitor exhibiting potent activity (IC 50 2 nM), effectively targets Pseudomonas aeruginosa</p>Formula:C21H11D7F3N5O3Colore e forma:SolidPeso molecolare:452.44BRD-4592
CAS:<p>BRD-4592 is an allosteric inhibitor targeting tryptophan synthase (TrpAB) of Mycobacterium tuberculosis. It binds at the α-β subunit interface of TrpAB, with an IC50 of 70.9 nM for the α subunit and 22.6 nM for the β subunit.</p>Formula:C17H15FN2OColore e forma:SolidPeso molecolare:282.312BRL-42715
CAS:<p>BRL-42715 is an effective inhibitor of bacterial beta-lactamases.</p>Formula:C10H7N4NaO3SPurezza:98%Colore e forma:SolidPeso molecolare:286.24ZIKV-IN-4
<p>ZIKV-IN-4 is a low cytotoxic, acid-stable anti-ZIKV agent with an EC50 value of 3.49 μM. ZIKV-IN-4 exhibited potent inhibition of ZIKV NS5 MTase.</p>Formula:C33H37NO4Colore e forma:SolidPeso molecolare:511.65RCB18350
CAS:<p>RCB18350 is an antituberculosis agent and an isoxazole derivative. It demonstrates bacteriostatic properties by inhibiting the growth of Mycobacterium tuberculosis, with a minimum inhibitory concentration (MIC) of 1.25 μg/mL. RCB18350 is effective against multi-drug resistant Mycobacterium tuberculosis (MDR-TB) clinical isolates, Mycobacterium bovis BCG, and Mycobacterium avium, all of which are slow-growing mycobacteria.</p>Formula:C19H18F3N3O4SColore e forma:SolidPeso molecolare:441.424CMX990
CAS:<p>CMX990, a SARS-CoV-2 3CL protease inhibitor, exhibits EC90 values of 9.6 nM in human bronchial epithelial cells (HBECs) and 101 nM in HeLa-ACE2 cells. It also demonstrates good ADME and pharmacokinetic properties [1].</p>Formula:C22H32F3N3O6Colore e forma:SolidPeso molecolare:491.50HIV-1 inhibitor-17
<p>HIV-1 inhibitor-18 blocks HIV-1 capsid, acts on NL4-3 strain (EC50: 2.57 μM), has low cytotoxicity (MT-4 CC50: >8.55).</p>Formula:C32H32N4O5SColore e forma:SolidPeso molecolare:584.69DHX9-IN-19
CAS:<p>DHX9-IN-19 (compound 3) is an orally active inhibitor of DHX9, playing a significant role in cancer research.</p>Formula:C20H21ClN4O4S2Colore e forma:SolidPeso molecolare:480.988HT1171
CAS:<p>HT1171 is a potent and selective inhibitor of the Mycobacterium tuberculosis proteasome. It exhibits strong antitubercular activity against Mycobacterium tuberculosis H37Rv, with a MIC90 of 2 μg/mL and MIC of 4 μg/mL. At a concentration of 100 μM, HT1171 shows an inhibition rate of 53.8% against normal human liver cells (L02). HT1171 is applicable in antituberculosis drug research.</p>Formula:C7H4N2O4S2Colore e forma:SolidPeso molecolare:244.248Antibacterial agent 261
CAS:<p>Antibacterialagent 261 (compound 43) is a potent inhibitor of the peptide deformylase (PDF) enzyme, demonstrating IC50 values of 2.5 nM against Staphylococcus aureus (S. aureus) and 10.6 nM against Escherichia coli (E. coli).</p>Formula:C18H24N4O3S2Colore e forma:SolidPeso molecolare:408.538Antibacterial agent 174
CAS:<p>Compound 174 (Compound 5g), an antibacterial agent, exhibits potent anti-infective properties in vivo along with appreciable pharmacokinetic profiles. This highly active substance demonstrates favorable biofilm removal capabilities, low hemolysis, and acceptable mammalian cell toxicity [1].</p>Formula:C25H30FN2NaO5Colore e forma:SolidPeso molecolare:480.5Methyl piperazine-2-carboxylate
CAS:<p>Methyl piperazine-2-carboxylate (compound 4) is a potent activator of METTL3/METTL14/WTAP. It enhances the production of HIV-1p24 viral particles and increases the level of N6-methyladenosine in the viral RNA genome.</p>Formula:C6H12N2O2Colore e forma:SolidPeso molecolare:144.172Antibacterial agent 172
CAS:<p>Antibacterial Agent 172 (Compound 6a), a <i>Clostridioides difficile (Cd) SpoVD inhibitor with an IC50 value of 89 nM, effectively inhibits the sporulation of Clostridioides difficile. It is useful for research on bacterial infections [1].</p>Formula:C21H21N9O5S2Colore e forma:SolidPeso molecolare:543.58MAY0132
CAS:<p>MAY0132 is a potent and selective EPAC2 inhibitor with an IC50 of 0.4 μM. It significantly inhibits the replication of HMPV, AdV, and RSV, reduces cytokine/chemokine production induced by viral infections, and suppresses NF-κB activation. MAY0132 exhibits antiviral activity and can be used in respiratory virus infection research.</p>Formula:C16H15ClF3NColore e forma:SolidPeso molecolare:313.745HBV-IN-11
CAS:<p>HBV-IN-11 is a potent inhibitor of HBsAg secretion (EC50: 0.46 μM).</p>Formula:C21H24ClNO6Colore e forma:SolidPeso molecolare:421.87Antifungal agent 12
<p>Antifungal agent 12 is a new fluconazole-like compound that exhibits good antifungal effects.</p>Formula:C20H16F3N7O2S2Colore e forma:SolidPeso molecolare:507.51Antibacterial agent 87
<p>Antibacterial agent 87 is an effective antibacterial agent that acts on MRSA (MIC: 0.125 μg/ml), MRSE (MIC: 0.0625 μg/ml) and S. aureus (MIC: 0.0625 μg/ml).</p>Formula:C31H46N2O6SColore e forma:SolidPeso molecolare:574.77FG-2101
CAS:<p>FG-2101 is a selective, orally active non-hydroxamate LpxC inhibitor with an IC50 of approximately 1 nM. It demonstrates exceptional selectivity over other bacterial and human metalloproteases. FG-2101 is useful for studying infections caused by Gram-negative bacteria, including resistant strains.</p>Formula:C30H32N5O6PColore e forma:SolidPeso molecolare:589.579Antibacterial agent 77
<p>Antibacterial agent 77 (compound 12) is an antibacterial agent [1].</p>Formula:C22H27N3OSColore e forma:SolidPeso molecolare:381.53HIV-1 inhibitor-61
CAS:<p>HIV-1 Inhibitor-61 (2c) serves as a potent inhibitor of HIV-1 reverse transcriptase, exhibiting an EC50 value of 0.07 nM in NL4-3 wt MT-4 cells [1].</p>Formula:C24H24F2N2O2SColore e forma:SolidPeso molecolare:442.52GSK-3036656 free base
CAS:<p>GSK656 (GSK3036656) inhibits Mtb LeuRS with IC50 of 0.20 μM, promising for tuberculosis treatment.</p>Formula:C10H13BClNO4Colore e forma:SolidPeso molecolare:257.48PptT-IN-3
<p>PptT-IN-3 (5p), an inhibitor of PptT in Mycobacterium tuberculosis, IC50=3.5μM, is key for TB research.</p>Formula:C16H27N5O3SColore e forma:SolidPeso molecolare:369.48RhlR antagonist 1
<p>RhlR antagonist 1: IC50 of 26 μM, selective for RhlR, inhibits P. aeruginosa biofilm and virulence factors.</p>Formula:C12H10F2OColore e forma:SolidPeso molecolare:208.2HBV-IN-18
<p>HBV-IN-18 (Compound 3) is an HBV capsid assembly modulator (CpAM) (EC50: 2790 nM).</p>Formula:C17H15F6N5O2Colore e forma:SolidPeso molecolare:435.32SARS-CoV-2 3CLpro-IN-32
CAS:<p>SARS-CoV-2 3CLpro-IN-32 (compound B16) is a potent inhibitor of the SARS-CoV-2 3CLpro enzyme, with an IC50 of 0.109 μM. It also demonstrates antiviral activity against the coronavirus HCoV-OC43, with an EC50 of 1.99 μM.</p>Formula:C30H37N3O4S3Colore e forma:SolidPeso molecolare:599.83HBV/HDV-IN-3
CAS:<p>HBV/HDV-IN-3 (Compd 1) acts as a dual inhibitor for HBV and HDV, demonstrating an efficacy (EC 50) below 50 nM against HBV .</p>Formula:C28H27BrF3N5O3Colore e forma:SolidPeso molecolare:618.44Chitin synthase inhibitor 8
<p>Chitin synthase inhibitor 8 is a chitin synthase (CHS) inhibitor with broad-spectrum antifungal effects that can be used in studies related to fungal infections</p>Formula:C23H23N3O5Colore e forma:SolidPeso molecolare:421.45NS2B/NS3-IN-5
<p>Compound 25b inhibits DENV2/ZIKV NS2B/NS3 proteases; IC50: ZIKV 0.67μM, DENV2 4.38μM.</p>Formula:C14H9IN2O3SColore e forma:SolidPeso molecolare:412.2BM635 hydrochloride
<p>BM635 hydrochloride, an MmpL3 inhibitor, strongly blocks Divergent bacteriophage H37Rv (MIC50: 0.08 μM), with doubled in vivo potency.</p>Formula:C25H30ClFN2OColore e forma:SolidPeso molecolare:428.97NIP-22c
CAS:<p>NIP-22c, a novel inhibitor of coronavirus 3CL pro, exhibits antiviral activity [1]. The compound's EC50 values are 4.6 μM for Verona, 1.1 μM for Calu3, 0.1 μM for Caco2, and 0.6 μM for HBTEC-ALI.</p>Formula:C32H39N5O6Colore e forma:SolidPeso molecolare:589.68HCV-IN-40
CAS:<p>HCV-IN-39 is a potent oral drug inhibiting HCV, effective on GT1a (EC50: 0.259μM), GT1b (EC50: 0.434μM), GT1b CES1 (EC50: 0.069μM) replicons.</p>Formula:C21H26BrFN3O9PColore e forma:SolidPeso molecolare:594.32
