recettore 5-HT
I recettori 5-HT, noti anche come recettori della serotonina, sono un gruppo di recettori accoppiati alle proteine G (GPCR) che mediano gli effetti della serotonina, un neurotrasmettitore coinvolto nella regolazione dell'umore, dell'ansia, del sonno, dell'appetito e di altri processi fisiologici. Questi recettori sono suddivisi in diversi sottotipi, ciascuno con funzioni e proprietà farmacologiche distinte. I modulatori dei recettori 5-HT sono ampiamente studiati per il loro ruolo nel trattamento della depressione, dei disturbi d'ansia e di altre condizioni neuropsichiatriche. Presso CymitQuimica, offriamo una gamma di modulatori dei recettori 5-HT di alta qualità per supportare la tua ricerca in neurofarmacologia, disturbi dell'umore e segnalazione GPCR.
Trovati 1017 prodotti per "recettore 5-HT".
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Ansofaxine hydrochloride
CAS:Ansofaxine hydrochloride (LY03005) is a serotonin-norepinephrine-dopamine reuptake inhibitor (IC50s: 723, 763 and 491 nM, respectively).Formula:C24H32ClNO3Purezza:99.57% - 99.77%Colore e forma:SolidPeso molecolare:417.97AVN-492
CAS:AVN-49 is a potent and selective 5-HT6R Antagonist (Ki: 91 pM).Formula:C17H21N5O2SPurezza:99.81%Colore e forma:SolidPeso molecolare:359.45Ref: TM-T5179
1mg37,00€2mg50,00€5mg77,00€1mL*10mM (DMSO)85,00€10mg114,00€25mg225,00€50mg335,00€100mg484,00€ML 10302
CAS:ML 10302 is a potent 5-HT4 agonist with Ki of 1.07 nM, boosts bowel movement, and may aid in neurology research.Formula:C15H21ClN2O3Colore e forma:SolidPeso molecolare:312.79AC-90179 HCl
CAS:AC-90179 HCl: selective 5-HT2A inverse agonist, atypical antipsychotic, reduces hallucinogen-induced vasoconstriction.Formula:C23H31ClN2O2Purezza:99.71%Colore e forma:SolidPeso molecolare:402.96Nuciferine
CAS:Nuciferine ((-)-Nuciferine) is an alkaloid found within the plants Nymphaea caerulea and Nelumbo nucifera.Formula:C19H21NO2Purezza:98.76% - 99.79%Colore e forma:SolidPeso molecolare:295.38Naratriptan
CAS:Naratriptan is a selective agonist of 5-HT1 receptor and is is used for the treatment of migraine headaches.Formula:C17H25N3O2SPurezza:99.08%Colore e forma:SolidPeso molecolare:335.47Ref: TM-T8666
1mg39,00€2mg50,00€5mg73,00€1mL*10mM (DMSO)88,00€10mg92,00€25mg166,00€50mg240,00€100mg360,00€Escitalopram Oxalate
CAS:Escitalopram Oxalate ((S)-(+)Citalopram oxalate) is a selective serotonin (5-HT) reuptake inhibitor (SSRI) with Ki of 0.89 nM.Formula:C22H23FN2O5Purezza:97.39% - 99.73%Colore e forma:White SolidPeso molecolare:414.43Ref: TM-T6493
10mg37,00€1mL*10mM (DMSO)42,00€25mg52,00€50mg63,00€100mg86,00€200mg118,00€500mg187,00€1g268,00€Indophagolin
CAS:Indophagolin: autophagy inhibitor, IC50 140 nM; blocks P2X4, P2X1, P2X3 receptors, IC50s 2.71, 2.40, 3.49 μM.Formula:C19H15BrClF3N2O3SPurezza:99.76%Colore e forma:SolidPeso molecolare:523.75Vortioxetine hydrobromide
CAS:Vortioxetine hydrobromide (Lu AA21004 hydrobromide) is a serotonin (5-HT) modulator and stimulator (SMS), inhibits 5-HT1A/1B/3A/7 receptor and SERT (IC50: 15/33Formula:C18H22N2S·HBrPurezza:98.85% - 99.98%Colore e forma:White SolidPeso molecolare:379.36Dolasetron
CAS:Dolasetron (MDL-73147)(MDL-73147) is a serotonin 5-HT3 receptor antagonist. Dolasetron is used to treat nausea and vomiting following chemotherapy.Formula:C19H20N2O3Purezza:99.84% - 99.86%Colore e forma:SolidPeso molecolare:324.37Flibanserin hydrochloride
CAS:Flibanserin HCl: oral 5-HT1A agonist & 5-HT2A antagonist, Ki values 1 nM & 49 nM, for HSDD, has antidepressant/anxiolytic properties.Formula:C20H22ClF3N4OColore e forma:SolidPeso molecolare:426.87NLX-204 hydrochloride(2170405-10-2 free base)
NLX-204 hydrochloride is a potent and selective ERK1/2 phosphorylation-preferring serotonin 5 HT1A receptor agonist(pKi = 10.19).Formula:C20H23Cl2F2N3O2Purezza:99.59%Colore e forma:White SolidPeso molecolare:446.32Opiranserin hydrochloride
CAS:Opiranserin (VVZ-149) hydrochloride is a dual antagonist of glycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A), with IC50s of 0.86 and 1.3 μMFormula:C21H35ClN2O5Purezza:99.33%Colore e forma:SolidPeso molecolare:430.97Ref: TM-T9833
1mg90,00€5mg215,00€1mL*10mM (DMSO)236,00€10mg340,00€25mg618,00€50mg879,00€100mg1.224,00€500mg2.457,00€Adoprazine hydrochloride
CAS:Adoprazine hydrochloride is a dopamine D2 receptor antagonist and 5-HT1A receptor agonist potential antipsychotic drug.Formula:C24H25ClFN3O2Colore e forma:SolidPeso molecolare:441.93Anpirtoline free base
CAS:Anpirtoline: potent 5-HT1B agonist; lowers serotonin synthesis; reduces aggression; 5-HT3 antagonist; crosses blood-brain barrier.Formula:C10H13ClN2SColore e forma:SolidPeso molecolare:228.74Almotriptan Malate
CAS:Almotriptan Malate (PNU180638), a selective 5-HT1B/1D receptor agonist, is used in the therapy of Migraine attacks in adults.Formula:C17H25N3O2S·C4H6O5Purezza:99.95%Colore e forma:SolidPeso molecolare:469.55Lerisetron
CAS:Lerisetron is an antagonist of serotonin type 3 (5-HT3) receptor, with antiemetic activity.Formula:C18H20N4Purezza:99.15% - 99.82%Colore e forma:SolidPeso molecolare:292.38Cerlapirdine hydrochloride
CAS:Cerlapirdine/SAM-531, potent 5-HT6 antagonist, targets Alzheimer's and schizophrenia cognitive issues; phase II trials, promising efficacy, safe profile.Formula:C22H24ClN3O3SColore e forma:SolidPeso molecolare:445.96Rizatriptan sulfate
CAS:Rizatriptan sulfate is a selective serotonin 5-HTID receptor agonist derived from tryptamine.Formula:C15H21N5O4SColore e forma:SolidPeso molecolare:367.42S1RA hydrochloride
CAS:S1RA hydrochloride (E-52862 hydrochloride) is an effective and specific sigma-1 receptor(σ1R, Ki: 17 nM) antagonist, and has good selectivity against σ2R (Ki >Formula:C20H24ClN3O2Purezza:98% - 99.84%Colore e forma:SolidPeso molecolare:373.87Ref: TM-T4229
1mg35,00€5mg75,00€1mL*10mM (DMSO)84,00€10mg105,00€25mg205,00€50mg334,00€100mg492,00€500mg973,00€Nefazodone hydrochloride
CAS:Nefazodone hydrochloride (Serzone) is a serotoninergic modulating antidepressant that is used in therapy of depression, aggressive behavior and panic disorder.Formula:C25H33Cl2N5O2Purezza:99% - 99.86%Colore e forma:SolidPeso molecolare:506.47Ref: TM-T3275
5mg44,00€10mg66,00€1mL*10mM (DMSO)73,00€25mg114,00€50mg205,00€100mg309,00€200mg447,00€500mg735,00€Norfluoxetine Hydrochloride
CAS:Norfluoxetine Hydrochloride (Norfluoxetine HCl) is an active metabolite of fluoxetine. Fluoxetine is an antidepressant drug.Formula:C16H17ClF3NOPurezza:99.71%Colore e forma:SolidPeso molecolare:331.76Metadoxine
CAS:Metadoxine (Metadoxil) is a neurotransmitter stimulant.Formula:C8H11NO3·C5H7NO3Purezza:99.19%Colore e forma:White SolidPeso molecolare:298.29Cilansetron Hydrochloride
CAS:Cilansetron Hydrochloride can be used for irritable Bowel Syndrome (IBS) with Diarrhea Predominance.Formula:C20H24ClN3O2Colore e forma:SolidPeso molecolare:373.88Volinanserin
CAS:Volinanserin (MDL100907) is a potent 5-HT2 receptor antagonist with a Ki of 0.36 nM, 300x selective over 5-HT1c, alpha-1, and sigma receptors.Formula:C22H28FNO3Purezza:98.94% - 99.95%Colore e forma:SolidPeso molecolare:373.46Ref: TM-T5389
1mg39,00€5mg84,00€1mL*10mM (DMSO)92,00€10mg117,00€25mg220,00€50mg285,00€100mg371,00€200mg530,00€Ralmitaront
CAS:Ralmitaront (RO6889450) is a potent, orally active partial agonist of the trace amine-associated receptor 1 (TAAR1).Formula:C17H22N4O2Purezza:99.71% - 99.79%Colore e forma:SolidPeso molecolare:314.38Ref: TM-T9183
1mg105,00€5mg260,00€1mL*10mM (DMSO)286,00€10mg401,00€25mg668,00€50mg897,00€100mg1.243,00€200mg1.693,00€NPS ALX Compound 4a
CAS:NPS ALX Compound 4a is a potent and selective antagonist of 5-HT6 receptor (IC50 of 7.2 nM)Formula:C25H25N3O2SPurezza:98%Colore e forma:SolidPeso molecolare:431.55Pipamperone HCl
CAS:Pipamperone blocks 5-HT2A/B/C, D2/D3/D4, α1/α2 receptors; favors 5-HT2A/D4 over D2; negligible affinity for H1, mACh. Highly selective at low doses.Formula:C21H31ClFN3O2Colore e forma:SolidPeso molecolare:411.95Naratriptan hydrochloride
CAS:Naratriptan Hydrochloride, a selective 5-HT1 receptor agonist with anti-migraine effect, induces vasoconstriction and reduces inflammation in migraines.Formula:C17H25N3O2S·HClPurezza:99.17% - 99.93%Colore e forma:SolidPeso molecolare:371.937-Amino-4-(trifluoromethyl)coumarin
CAS:7-Amino-4-(trifluoromethyl)coumarin (Coumarin 151) is a 5-Hydroxytryptamine Receptor Subtype 1E (HTR1E) antagonist.Formula:C10H6F3NO2Purezza:97.31% - 97.84%Colore e forma:Yellow SolidPeso molecolare:229.16F-15599
CAS:F-15599 is a highly selective G-protein biased 5-HT1A receptor agonist(Ki : 3.4 nM).Formula:C19H21ClF2N4OPurezza:98.72%Colore e forma:White SolidPeso molecolare:394.85Ref: TM-T7281
1mg49,00€5mg92,00€1mL*10mM (DMSO)104,00€10mg152,00€25mg295,00€50mg477,00€100mg715,00€200mg982,00€Pirenperone
CAS:Pirenperone is a putative 5-HT2 receptor antagonist with the central antiserotonergic and antidopaminergic action.Formula:C23H24FN3O2Purezza:99.2%Colore e forma:SolidPeso molecolare:393.45Clomipramine
CAS:Clomipramine treats OCD, depression, chronic pain, and may lower suicide risk in seniors; works by hindering serotonin reuptake.Formula:C19H23ClN2Purezza:99.31% - 99.71%Colore e forma:SolidPeso molecolare:314.85Olanzapine HCl
CAS:Olanzapine HCl, an FDA-approved atypical antipsychotic for schizophrenia and bipolar disorder, resembles clozapine and quetiapine.Formula:C17H21ClN4SColore e forma:SolidPeso molecolare:348.89Cariprazine
CAS:Cariprazine (RGH-188) is a novel antipsychotic drug candidate that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderateFormula:C21H32Cl2N4OPurezza:99.68% - 99.87%Colore e forma:White SolidPeso molecolare:427.41Ref: TM-T4577
1mg49,00€5mg92,00€1mL*10mM (DMSO)103,00€10mg145,00€25mg281,00€50mg394,00€100mg550,00€200mg780,00€Naftopidil dihydrochloride
CAS:Naftopidil dihydrochloride (KT-611 2HCl) is a selective 5-HT1A and α1-adrenergic receptor antagonist with IC50 of 0.1 μM and 0.2 μM, respectively.Formula:C24H28N2O3·2HClPurezza:99.76%Colore e forma:SolidPeso molecolare:465.41Syk Inhibitor II dihydrochloride
CAS:Syk inhibitor II selectively blocks Syk (IC50 = 41 nM), impacting platelet function and inflammation, with lower potency against other kinases.Formula:C14H17Cl2F3N6OPurezza:98.53%Colore e forma:SolidPeso molecolare:413.22Ref: TM-T4391
1mg123,00€2mg200,00€5mg432,00€1mL*10mM (DMSO)432,00€10mg613,00€25mg897,00€50mg1.198,00€100mg1.611,00€GR 125743
CAS:GR 125743 is a novel antagonist of 5-HT1B/1D receptor.Formula:C25H28N4O2Purezza:99.76%Colore e forma:SolidPeso molecolare:416.52Ref: TM-T8737
1mg40,00€2mg52,00€5mg84,00€1mL*10mM (DMSO)93,00€10mg113,00€25mg222,00€50mg333,00€100mg495,00€SB-200646
CAS:SB-200646 is a selective and potent antagonist of 5-HT2B/5-HT2C receptorFormula:C15H14N4OPurezza:99.61%Colore e forma:SolidPeso molecolare:266.3MK 212 hydrochloride
CAS:MK 212 hydrochloride is a 5-HT2C receptor agonistFormula:C8H11ClN4·HClPurezza:99.88%Colore e forma:White SolidPeso molecolare:235.12Abaperidone Hydrochloride
CAS:Abaperidone Hydrochloride is an atypical antipsychotic, potently binging to5-HT2 receptors and D2 receptors.Formula:C25H26ClFN2O5Colore e forma:SolidPeso molecolare:488.94Epinastine hydrochloride
CAS:Epinastine hydrochloride (WAL-801CL HCl) is an antihistamine and mast cell stabilizer that is used in eye drops to treat allergic conjunctivitis.Formula:C16H15N3·HClPurezza:99.26% - 99.62%Colore e forma:SolidPeso molecolare:285.77Alprenolol hydrochloride
CAS:Alprenolol hydrochloride is a non-selective blocker of beta, and also is a antagonist of5-HT1A receptor.Formula:C15H24ClNO2Purezza:99.79%Colore e forma:White SolidPeso molecolare:285.81Temanogrel hydrochloride
CAS:Temanogrel hydrochloride is a serotonin antagonist and anti-platelet agent.Formula:C24H29ClN4O4Colore e forma:SolidPeso molecolare:472.97Dolasetron Mesylate hydrate
CAS:Dolasetron Mesylate hydrate blocks 5HT3 to prevent chemo and radiotherapy nausea.Formula:C20H26N2O7SPurezza:99.86% - 99.99%Colore e forma:White SolidPeso molecolare:438.49Zacopride
CAS:Zacopride is a selective agonist of inward rectifier potassium current (I K1) channel, inhibiting ventricular arrhythmias without affecting atrial arrhythmias.Formula:C15H20ClN3O2Purezza:98%Colore e forma:SolidPeso molecolare:309.79Cerlapirdine
CAS:Cerlapirdine (PF-05212365), a 5-HT6 receptor antagonist, is in trials for Alzheimer's and schizophrenia cognition issues.Formula:C22H23N3O3SPurezza:98.77%Colore e forma:White SolidPeso molecolare:409.5Ref: TM-T30798
1mg77,00€5mg166,00€1mL*10mM (DMSO)188,00€10mg260,00€25mg515,00€50mg740,00€100mg1.018,00€Cariprazine hydrochloride
CAS:Cariprazine hydrochloride (RGH188 hydrochloride) is an antipsychotic drug, is a D3 and D2 receptor partial agonist((Ki of 0.085 nM and 0.49 nM, respectively)Formula:C21H33Cl3N4OPurezza:99.78% - >99.99%Colore e forma:SolidPeso molecolare:463.87LY310762
CAS:LY310762 is a 5-HT1D receptor antagonist with Ki of 249 nM.Formula:C24H27FN2O2·HClPurezza:99.8%Colore e forma:SolidPeso molecolare:430.94Melitracen hydrochloride
CAS:Melitracen hydrochloride (Thymeol hydrochloride) , an antidepressant, is used as potential dopamine D1/2 receptor antagonist to treat depression.Formula:C21H26ClNPurezza:99.99%Colore e forma:Crystalline SolidPeso molecolare:327.90Ref: TM-T4274
10mg44,00€1mL*10mM (DMSO)48,00€25mg64,00€50mg93,00€100mg110,00€200mg161,00€500mg264,00€
