Naratriptan hydrochloride

CAS: 143388-64-1

Rif. TM-T6602

Informazioni sul prodotto

• Nome: Naratriptan hydrochloride
• Sinonimi: Naratriptan HCl, Amerge, Naramig, GR-85548A hydrochloride, 1H-Indole-5-ethanesulfonamide, N-methyl-3-(1-methyl-4-piperidinyl)-, hydrochloride (1:1), 1H-Indole-5-ethanesulfonamide, N-methyl-3-(1-methyl-4-piperidinyl)-, monohydrochloride, Amerge, Gr 85548A, N-Methyl-3-(1-methyl-4-piperidinyl)-1H-indole-5-ethanesulfonamide hydrochloride, N-Methyl-3-(1-methyl-4-piperidyl)indole-5-ethanesulfonamide monohydrochloride, N-methyl-2-[3-(1-methylpiperidin-4-yl)-1H-indol-5-yl]ethanesulfonamide hydrochloride (1:1), Naramig, Naratrex 1, Naratriptan HCl
• CAS: 143388-64-1

Descrizione

Naratriptan Hydrochloride is the hydrochloride salt form of naratriptan, a sulfonamide with selective serotonin (5-HT) 1 receptor agonistic activity and anti-migraine property. Naratriptan hydrochloride (GR-85548A hydrochloride) binds selectively and with high affinity to the 5-HT1D and 5-HT1B receptor subtypes. Activation of these 5-HT1D/B receptors located on intracranial blood vessels leads to vasoconstriction and provides relief of migraine headaches. Naratriptan hydrochloride may also exerts its effect by stimulation of 5-HT1D/1B receptors on sensory nerve endings in the trigeminal system thereby decreasing the release of pro-inflammatory neuropeptides.

• Marchio: Targetmol

Proprietà chimiche

• Peso molecolare: 371.93
• Formula: C₁₇H₂₅N₃O₂S·HCl
• Purezza: 99.89%
• Colore/Forma: Beige Solid