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GlyT

GlyT

Gli inibitori del trasportatore della glicina (GlyT) sono composti che bloccano la ricaptazione della glicina, un importante neurotrasmettitore inibitorio nel midollo spinale e nel tronco encefalico. Inibendo i trasportatori di glicina, questi composti aumentano la disponibilità di glicina nella fessura sinaptica, potenziando i suoi effetti inibitori sull'attività neuronale. Gli inibitori del GlyT sono di interesse per le loro potenziali applicazioni terapeutiche in condizioni come il dolore cronico, la spasticità e la schizofrenia. Presso CymitQuimica, offriamo inibitori del GlyT per supportare la tua ricerca nella gestione del dolore, nel controllo motorio e nei disturbi neuropsichiatrici.

Trovati 25 prodotti di "GlyT"

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  • LY2365109 hydrochloride
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    LY2365109 hydrochloride

    CAS:
    <p>LY2365109 hydrochloride is a potent and selective GlyT1 inhibitor, with an IC50 of 15.8 nM for glycine uptake in cells over-expressing hGlyT1a.</p>
    Formula:C22H28ClNO5
    Purezza:98.27%
    Colore e forma:Solid
    Peso molecolare:421.91

    Ref: TM-T11908

  • DCCCyb
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    DCCCyb

    CAS:
    <p>DCCCyb: oral GlyT1 inhibitor with high in vivo occupancy in rhesus monkeys, confirmed by PET tracer displacement.</p>
    Formula:C22H29Cl2NO3S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:458.44

    Ref: TM-T25292

  • Logo CymitQuimica
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    (Rac)-Oleoylcarnitine

    CAS:
    (Rac)-Oleoylcarnitine, an endogenous acylcarnitine, acts as a potential non-competitive inhibitor of glycine transporter 2 (GLYT2) and can be used as a pain suppressant.
    Formula:C25H47NO4
    Peso molecolare:425.65

    Ref: TM-TN8218

  • 8-hydroxy Amoxapine
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    8-hydroxy Amoxapine

    CAS:
    <p>8-hydroxy Amoxapine is a metabolite of the tetracyclic antidepressant amoxapine .1,2</p>
    Formula:C17H16ClN3O2
    Colore e forma:Solid
    Peso molecolare:329.78

    Ref: TM-T37161

  • SSR504734 HCl
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    SSR504734 HCl

    CAS:
    <p>SSR504734 inhibits GlyT1 in humans, rats, mice (IC50=18, 15, 38 nM); treats schizophrenia, anxiety, depression orally.</p>
    Formula:C20H21Cl2F3N2O
    Purezza:98.05% - 99.93%
    Colore e forma:Solid
    Peso molecolare:433.30

    Ref: TM-T90597

  • SSR504734
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    SSR504734

    CAS:
    SSR504734 is a novel potent glycine transporter 1 (GlyT1) inhibitor.
    Formula:C20H20ClF3N2O
    Colore e forma:Solid
    Peso molecolare:396.83

    Ref: TM-T28858

  • Bitopertin
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    Bitopertin

    CAS:
    Bitopertin (Paliflutine) (RG1678, RO-4917838) is a potent inhibitor of glycine transporter 1 (GlyT1), with Ki of 8.1 nM for human hGlyT1b and IC50 of 22-25 nM
    Formula:C21H20F7N3O4S
    Purezza:98.57% - 98.71%
    Colore e forma:Solid
    Peso molecolare:543.46

    Ref: TM-T6788

  • Org 25543 hydrochloride
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    Org 25543 hydrochloride

    CAS:
    Org 25543 hydrochloride is a potent and selective glycine transporter type 2 (GlyT2) inhibitor (IC50 = 16 nM for hGlyT2).
    Formula:C24H33ClN2O4
    Purezza:99.26%
    Colore e forma:Solid
    Peso molecolare:448.983

    Ref: TM-T22126

  • Opiranserin hydrochloride
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    Opiranserin hydrochloride

    CAS:
    Opiranserin (VVZ-149) hydrochloride is a dual antagonist of glycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A), with IC50s of 0.86 and 1.3 μM
    Formula:C21H35ClN2O5
    Purezza:99.33%
    Colore e forma:Solid
    Peso molecolare:430.97

    Ref: TM-T9833

  • Sarcosine
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    Sarcosine

    CAS:
    Sarcosine (Methylglycine) is a competitive inhibitor of the type I glycine transporter (GlyT1) and an N-methyl-D-aspartate receptor (NMDAR) co-agonist.
    Formula:C3H7NO2
    Purezza:99.90%
    Colore e forma:Deliquescent Water Soluble Physical Description Deliquescent Crystals Or Powder Has A Sweetish Taste (Ntp 1992)
    Peso molecolare:89.09

    Ref: TM-T6975

  • ASP2535
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    ASP2535

    CAS:
    <p>ASP2535 is a potent, selective, orally bioavailable, brain permeable and centrally-active glycine transporter-1 (GlyT1) inhibitor.ASP2535 can improve cognitive</p>
    Formula:C22H18N6O
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:382.42

    Ref: TM-T14334

  • Org-25935
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    Org-25935

    CAS:
    Org-25935, a GlyT-1 inhibitor, is used potentially for the treatment of schizophrenia and alcohol dependence.
    Formula:C21H26ClNO3
    Colore e forma:Solid
    Peso molecolare:375.89

    Ref: TM-T28260

  • Tilapertin
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    Tilapertin

    CAS:
    Tilapertin is an oral glycine transporter type-1 inhibitor.
    Formula:C20H21F3N2O2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:378.39

    Ref: TM-T17096

  • Org 24598
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    Org 24598

    CAS:
    Potent GlyT1b inhibitor, IC50 = 6.9 nM; little effect on GlyT-2, adrenoceptors, dopamine, 5HT receptors, GABA transporters.
    Formula:C19H20F3NO3
    Colore e forma:Solid
    Peso molecolare:367.36

    Ref: TM-T37699

  • NFPS
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    NFPS

    CAS:
    NFPS exerts neuroprotection via glyR alpha1 subunit in the rat model of transient focal cerebral ischaemia and reperfusion.
    Formula:C24H24FNO3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:393.45

    Ref: TM-T16292

  • MPDC
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    MPDC

    CAS:
    MPDC acts as a competitive inhibitor against the Na+-dependent high-affinity glutamate transporter within forebrain synaptosomes.
    Formula:C7H9NO4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:171.15

    Ref: TM-T12099

  • LY 2365109 hydrochloride
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    LY 2365109 hydrochloride

    CAS:
    glycine transporter 1 (GlyT1) inhibitor
    Formula:C22H27NO5
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:385.45

    Ref: TM-T22945

  • PF-03463275 2HCl
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    PF-03463275 2HCl

    CAS:
    <p>PF-03463275 is an orally available, CNS-penetrant inhibitor of SLC6A9, a GlyT1 glycine transporter.</p>
    Formula:C19H24Cl3FN4O
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:449.78

    Ref: TM-T28364

  • Bitopertin (R enantiomer)
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    Bitopertin (R enantiomer)

    CAS:
    Bitopertin R enantiomer (RG1678 R enantiomer) is the R-enantiomer of Bitopertin.
    Formula:C21H20F7N3O4S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:543.46

    Ref: TM-T10552

  • GSK931145
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    GSK931145

    CAS:
    GSK931145 is a positron emission tomography (PET) radioligand, it is suitable for quantifying glycine transporter (GlyT1) availability in the living brain.
    Formula:C23H30N2O
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:350.5

    Ref: TM-T27494