GlyT
Gli inibitori del trasportatore della glicina (GlyT) sono composti che bloccano la ricaptazione della glicina, un importante neurotrasmettitore inibitorio nel midollo spinale e nel tronco encefalico. Inibendo i trasportatori di glicina, questi composti aumentano la disponibilità di glicina nella fessura sinaptica, potenziando i suoi effetti inibitori sull'attività neuronale. Gli inibitori del GlyT sono di interesse per le loro potenziali applicazioni terapeutiche in condizioni come il dolore cronico, la spasticità e la schizofrenia. Presso CymitQuimica, offriamo inibitori del GlyT per supportare la tua ricerca nella gestione del dolore, nel controllo motorio e nei disturbi neuropsichiatrici.
Trovati 26 prodotti per "GlyT".
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
LY2365109 hydrochloride
CAS:LY2365109 hydrochloride is a potent and selective GlyT1 inhibitor, with an IC50 of 15.8 nM for glycine uptake in cells over-expressing hGlyT1a.Formula:C22H28ClNO5Purezza:98.27%Colore e forma:White SolidPeso molecolare:421.918-hydroxy Amoxapine
CAS:8-hydroxy Amoxapine is a metabolite of the tetracyclic antidepressant amoxapine .1,2Formula:C17H16ClN3O2Colore e forma:SolidPeso molecolare:329.78DCCCyb
CAS:DCCCyb: oral GlyT1 inhibitor with high in vivo occupancy in rhesus monkeys, confirmed by PET tracer displacement.Formula:C22H29Cl2NO3SPurezza:98%Colore e forma:SolidPeso molecolare:458.44Org 24598 lithium salt
CAS:Org 24598 lithium salt is a GlyT-1 inhibitor of glycine transporter 1.Formula:C19H19F3LiNO3Colore e forma:SolidPeso molecolare:373.3(Rac)-Oleoylcarnitine
CAS:(Rac)-Oleoylcarnitine, an endogenous acylcarnitine, acts as a potential non-competitive inhibitor of glycine transporter 2 (GLYT2) and can be used as a pain suppressant.Formula:C25H47NO4Peso molecolare:425.65SSR504734 HCl
CAS:SSR504734 inhibits GlyT1 in humans, rats, mice (IC50=18, 15, 38 nM); treats schizophrenia, anxiety, depression orally.Formula:C20H21Cl2F3N2OPurezza:98.05% - 99.93%Colore e forma:SolidPeso molecolare:433.30Bitopertin
CAS:Bitopertin (Paliflutine) (RG1678, RO-4917838) is a potent inhibitor of glycine transporter 1 (GlyT1), with Ki of 8.1 nM for human hGlyT1b and IC50 of 22-25 nMFormula:C21H20F7N3O4SPurezza:98.57% - 98.71%Colore e forma:SolidPeso molecolare:543.46SSR504734
CAS:SSR504734 is a novel potent glycine transporter 1 (GlyT1) inhibitor.Formula:C20H20ClF3N2OColore e forma:SolidPeso molecolare:396.83Org 25543 hydrochloride
CAS:Org 25543 hydrochloride is a potent and selective glycine transporter type 2 (GlyT2) inhibitor (IC50 = 16 nM for hGlyT2).Formula:C24H33ClN2O4Purezza:99.26%Colore e forma:White SolidPeso molecolare:448.983Opiranserin hydrochloride
CAS:Opiranserin (VVZ-149) hydrochloride is a dual antagonist of glycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A), with IC50s of 0.86 and 1.3 μMFormula:C21H35ClN2O5Purezza:99.33%Colore e forma:SolidPeso molecolare:430.97Ref: TM-T9833
1mg90,00€5mg215,00€1mL*10mM (DMSO)236,00€10mg340,00€25mg618,00€50mg879,00€100mg1.224,00€500mg2.457,00€Sarcosine
CAS:Sarcosine (Methylglycine) is a competitive inhibitor of the type I glycine transporter (GlyT1) and an N-methyl-D-aspartate receptor (NMDAR) co-agonist.Formula:C3H7NO2Purezza:99.90%Colore e forma:SolidPeso molecolare:89.09MPDC
CAS:MPDC acts as a competitive inhibitor against the Na+-dependent high-affinity glutamate transporter within forebrain synaptosomes.Formula:C7H9NO4Purezza:98%Colore e forma:SolidPeso molecolare:171.15Org-25935
CAS:Org-25935, a GlyT-1 inhibitor, is used potentially for the treatment of schizophrenia and alcohol dependence.Formula:C21H26ClNO3Colore e forma:SolidPeso molecolare:375.89NFPS
CAS:NFPS exerts neuroprotection via glyR alpha1 subunit in the rat model of transient focal cerebral ischaemia and reperfusion.Formula:C24H24FNO3Purezza:98%Colore e forma:SolidPeso molecolare:393.45PF-03463275 2HCl
CAS:PF-03463275 is an orally available, CNS-penetrant inhibitor of SLC6A9, a GlyT1 glycine transporter.Formula:C19H24Cl3FN4OPurezza:98%Colore e forma:SolidPeso molecolare:449.78Bitopertin (R enantiomer)
CAS:Bitopertin R enantiomer (RG1678 R enantiomer) is the R-enantiomer of Bitopertin.Formula:C21H20F7N3O4SPurezza:98%Colore e forma:SolidPeso molecolare:543.46GSK931145
CAS:GSK931145 is a positron emission tomography (PET) radioligand, it is suitable for quantifying glycine transporter (GlyT1) availability in the living brain.Formula:C23H30N2OPurezza:98%Colore e forma:SolidPeso molecolare:350.5Org 24598
CAS:Potent GlyT1b inhibitor, IC50 = 6.9 nM; little effect on GlyT-2, adrenoceptors, dopamine, 5HT receptors, GABA transporters.Formula:C19H20F3NO3Colore e forma:SolidPeso molecolare:367.36Tilapertin
CAS:Tilapertin is an oral glycine transporter type-1 inhibitor.Formula:C20H21F3N2O2Purezza:98%Colore e forma:SolidPeso molecolare:378.39Opiranserin
CAS:Opiranserin is a development as an injectable agent for the treatment of postoperative pain.Formula:C21H34N2O5Purezza:98%Colore e forma:SolidPeso molecolare:394.51PF-03463275
CAS:PF-03463275 is an orally active and selective reversible inhibitor of competitive glycine transporter protein-1 (GlyT1) with a Ki of 11.6 nM.PF-03463275 has CNSFormula:C19H22ClFN4OPurezza:99.95%Colore e forma:SolidPeso molecolare:376.86Ref: TM-T61564
50mgPrezzo su richiesta1mg52,00€5mg113,00€1mL*10mM (DMSO)124,00€10mg177,00€25mg299,00€LY 2365109 hydrochloride
CAS:glycine transporter 1 (GlyT1) inhibitorFormula:C22H27NO5Purezza:98%Colore e forma:SolidPeso molecolare:385.45ASP2535
CAS:ASP2535 is a potent, selective, orally bioavailable, brain permeable and centrally-active glycine transporter-1 (GlyT1) inhibitor.ASP2535 can improve cognitiveFormula:C22H18N6OPurezza:98%Colore e forma:SolidPeso molecolare:382.42GlyT1 Inhibitor 1
CAS:GlyT1 Inhibitor 1 is a selective and potent GlyT1 inhibitor, inhibiting rGlyT1, used in research on neurological disorders.Formula:C22H21N5O2Colore e forma:SolidPeso molecolare:387.43ALX-1393
CAS:ALX-1393 is a selective GlyT2 inhibitor that effectively reduces neuronal action potential activity in a concentration-dependent manner and inhibits theFormula:C23H22FNO4Purezza:99.83%Colore e forma:SolidPeso molecolare:395.42Ref: TM-T14198
1mg1.243,00€5mg2.520,00€1mL*10mM (DMSO)2.592,00€10mg3.402,00€25mg5.059,00€50mg6.832,00€100mg8.883,00€Iclepertin
CAS:Iclepertin (BI-425809) is a GlyT1 inhibitor.Iclepertin is used for the treatment of Alzheimer;s disease and other CNS disorders.Formula:C20H18F6N2O5SPurezza:99.21% - 99.66%Colore e forma:SolidPeso molecolare:512.42Ref: TM-T37089
1mg90,00€2mg114,00€5mg160,00€1mL*10mM (DMSO)173,00€10mg212,00€25mg349,00€50mg522,00€100mg783,00€200mg1.054,00€
