Beta amiloide
Gli inibitori del beta-amiloide sono composti che mirano specificamente a inibire la formazione o l'aggregazione dei peptidi beta-amiloidi, coinvolti in modo critico nella patogenesi della malattia di Alzheimer. L'accumulo di placche di beta-amiloide nel cervello è uno dei tratti patologici distintivi della malattia, contribuendo alla disfunzione neuronale e al declino cognitivo. Inibendo l'aggregazione del beta-amiloide, questi inibitori sono studiati come potenziali agenti terapeutici per rallentare o prevenire la progressione della malattia di Alzheimer. Presso CymitQuimica, offriamo una gamma di inibitori del beta-amiloide di alta qualità per supportare la tua ricerca nella neurodegenerazione, nell'aggregazione proteica e nella terapia dell'Alzheimer.
Trovati 219 prodotti di "Beta amiloide"
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Birtamimab
CAS:<p>Birtamimab (NEOD001) is a monoclonal antibody selectively targeting and depleting amyloid protein, used in research on light chain amyloidosis.</p>Purezza:>95%Colore e forma:LiquidChlorzoxazone
CAS:Chlorzoxazone (Chlorzoxazon) is a Muscle Relaxant. The physiologic effect of chlorzoxazone is by means of Centrally-mediated Muscle Relaxation.Formula:C7H4ClNO2Purezza:99.49% - 99.6%Colore e forma:SolidPeso molecolare:169.57Eprodisate disodium
CAS:Eprodisate disodium (NC-503) is a negatively charged sulfonated inhibitor of fibrillogenesis, that can be used in the treatment of amyloid A (AA) amyloidosis.Formula:C3H6Na2O6S2Purezza:99.88%Colore e forma:White Coarse PowderPeso molecolare:248.19Lecanemab
CAS:Lecanemab (BAN-2401) is an IgG1 monoclonal antibody targeting soluble aggregated beta amyloid (Abeta) for the study of cognitive disorders.Purezza:97.3% (SEC-HPLC) - >95.0% (SDS-PAGE); 100% (SEC-HPLC)Colore e forma:LiquidALZ-801
CAS:ALZ-801, an oral valine-prodrug of tramiprosate, enhances treatment of Alzheimer's by inhibiting β-amyloid aggregation with better PK and tolerance.Formula:C8H18N2O4SPurezza:99.36%Colore e forma:SolidPeso molecolare:238.3Donanemab
CAS:<p>Donanemab (LY3002813), a humanized IgG1 antibody, targets N-terminal Aβ for potential early Alzheimer's research.</p>Purezza:95%Colore e forma:LiquidCromolyn sodium
CAS:Cromolyn sodium (FPL-670) is a chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells.Formula:C23H14Na2O11Purezza:99.4% - 99.95%Colore e forma:Colorless Crystals From Ethanol + Ether White Crystalline PowderPeso molecolare:512.33Glimepiride
CAS:Glimepiride (HOE-490) is a long-acting, third-generation sulfonylurea with hypoglycemic activity.Formula:C24H34N4O5SPurezza:97.84% - 98.87%Colore e forma:White Cyrstalline SolidPeso molecolare:490.62Gantenerumab
CAS:Gantenerumab (R-1450) is a humanized antibody targeting amyloid-β (Aβ), used in studies of Alzheimer's disease.Purezza:>95%Colore e forma:LiquidPeso molecolare:146.28LY 2389575 hydrochloride
CAS:LY2389575 hydrochloride is a selective mGlu3 NAM with 190 nM IC50, increases Mrc1, and aids Alzheimer's research.Formula:C15H16BrCl3N4Purezza:99.9%Colore e forma:SolidPeso molecolare:438.58Methoxy-X04
CAS:<p>Methoxy-X04, a derivative of Congo red and Chrysamine-G, is a brain-permeable fluorescent probe for amyloid-β (Aβ).</p>Formula:C23H20O3Purezza:98.96%Colore e forma:SolidPeso molecolare:344.4β-Amyloid (10-20)
CAS:Amyloid β-Protein (10-20) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.Amyloid β protein fragment containing the α-Formula:C71H99N17O16Purezza:98%Colore e forma:Lyophilized PowderPeso molecolare:1446.65β-Amyloid (10-35), amide
CAS:β-Amyloid (10-35), amide, is a chemical compound consisting of 26 amino acids, specifically residues 10-35 of the Aβ peptide.Formula:C133H205N35O36SPurezza:98%Colore e forma:SolidPeso molecolare:2902.33AChE/Aβ-IN-6
BACE1-IN-15 (compound 4j) serves as an effective inhibitor of BACE1 (β-secretase), efficiently mitigating the copper-induced toxicity of Aβ, with an EC50 value of 0.68 μM.Colore e forma:Odour SolidCrenezumab
CAS:Crenezumab (MABT 5102A) is a fully humanized anti-amyloid-beta antibody that binds to multiple forms of amyloid-beta (Aβ) for the study of Alzheimer's disease.Purezza:97.5% (SDS-PAGE); 95.3% (SEC-HPLC) - 97.5% (SDS-PAGE); 95.3% (SEC-HPLC)Colore e forma:LiquidPep63
CAS:Pep63, a neuroprotective peptide (VFQVRARTVA), enhances synaptic plasticity and memory. It competitively binds with Aβ1-42 oligomers, thereby inhibiting the formation of Aβ fibrils. Pep63 is employed in research focused on Alzheimer's disease (AD).Formula:C51H87N17O13Peso molecolare:1146.34Merinetug
CAS:Merinetug is a humanized IgG1κ antibody that targets Amyloid Beta (Aβ). Its corresponding isotype control is Human IgG1 kappa, Isotype Control.Colore e forma:Liquidβ-Amyloid (25-35) acetate
β-Amyloid (25-35) acetate is the Aβ(25-35) fragment of amyloid beta peptide, neurotoxicity, construct Alzheimer's disease cell and animal models.Purezza:98.26%C18 L-erythro Ceramide (d18:1/18:0)
CAS:C18 L-erythro Ceramide, a natural stereoisomer, inhibits rat brain mt-CDase with IC50 of 8.8 μM.Formula:C36H71NO3Colore e forma:SolidPeso molecolare:565.95Aducanumab
CAS:<p>Aducanumab (BIIB037) is an IgG1 antibody targeting amyloid beta to treat Alzheimer's; it's brain-permeable.</p>Purezza:95% - 97.10%Colore e forma:LiquidPeso molecolare:145.93 kDaTrontinemab
CAS:<p>Trontinemab, a bispecific humanized IgG1-κ antibody, targets the amyloid beta A4 precursor protein (APP) and transferrin receptor p90, CD71 (TFRC).</p>Purezza:96.77% - 99%Colore e forma:Liquidβ-Amyloid (33-40)
CAS:β-Amyloid (33-40) is a peptide comprising amino acids 33 to 40 of the beta-amyloid protein.Formula:C32H58N8O9SPurezza:98%Colore e forma:SolidPeso molecolare:730.92GSK-3β inhibitor 27
GSK-3β inhibitor27 (Compound 1c) is a reversible, competitive inhibitor of GSK-3β with an IC50 value of 2.2 μM. It inhibits tau hyperphosphorylation and reduces Aβ protein aggregation, demonstrating metal chelation and neuroprotective potential. GSK-3β inhibitor27 is promising for research into neurodegenerative diseases, such as Alzheimer's disease.Formula:C16H17ClN4O2Colore e forma:SolidPeso molecolare:332.79β-Amyloid (13-27)
CAS:β-Amyloid (13-27) is a peptide consisting of amino acid of 13 to 27 of beta amyloid protein.Formula:C84H126N24O24Purezza:98%Colore e forma:SolidPeso molecolare:1856.05β-Amyloid (1-16)
CAS:β-Amyloid (1-16) is an amyloidogenic protein fragment with a sequence derived from β-amyloid.Formula:C84H119N27O28Purezza:98%Colore e forma:SolidPeso molecolare:1955.041H-Indole-3-carboxylic acid, 5-[2-hydroxy-3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]propoxy]-2-methyl-1-(4-methylphenyl)-, ethyl ester
CAS:<p>Compound 5936-0108对β-淀粉样蛋白可能具有调节作用。</p>Formula:C26H34N2O7Purezza:99.44%Colore e forma:SoildPeso molecolare:486.56Chemerin-9 (149-157) TFA
Chemerin-9 (149-157) TFA is a peptide located at positions 149-157 of chemerin-9, acting as a ChemR23/CMKLR1 agonist.Formula:C56H67F3N10O15Purezza:99.77%Colore e forma:SolidPeso molecolare:1177.18β-Amyloid Protein Precursor 770 (135-155)
CAS:<p>Beta-Amyloid Protein Precursor 770 (135-155)Aβ Protein Precursor 770 (135-155)</p>Formula:C116H172N35O31S2Purezza:98%Colore e forma:SolidPeso molecolare:2617.96β-Amyloid (4-10)
CAS:Antibodies corresponding to beta-amyloid (4-10) are effective in vivo inhibitors of cytotoxicity, amyloid plaque formation and special memory disturbances inFormula:C39H52N12O12Purezza:98%Colore e forma:SolidPeso molecolare:880.9β-Amyloid (12-28)
CAS:Amyloid β-peptide fragment; minimum section required to bind to brain proteins.Formula:C89H135N25O25Purezza:98%Colore e forma:SolidPeso molecolare:1955.18RAGE antagonist peptide
CAS:<p>RAGE antagonist blocks S100P/A4, HMGB-1; hinders glioma growth, metastasis; reduces PDAC cell growth, NF-κB activity; counters TDI effects in mice.</p>Formula:C57H101N13O17SPurezza:98%Colore e forma:SolidPeso molecolare:1272.56β-Amyloid (1-28)
CAS:β-Amyloid (1-28) is a β-Amyloid protein fragment involved in metal binding.Formula:C145H209N41O46Purezza:98%Colore e forma:SolidPeso molecolare:3262.51β-Amyloid (1-40)
CAS:Amyloid β1-40 is one of the fragments generated after cleavage of the amyloid peptide precursor protein by β and γ secretases.Formula:C194H295N53O58SPurezza:98%Colore e forma:SolidPeso molecolare:4329.82γ-Secretase Modulators
CAS:gamma-Secretase Modulators serves as a useful treatment for Alzheimer's disease by inhibiting the production of Amyloid-β.Formula:C26H24F3N3O3Purezza:98%Colore e forma:SolidPeso molecolare:483.48Aβ-IN-6
Aβ-IN-6 is an orally active compound exhibiting anti-inflammatory, antioxidant, and anti-oligomeric activities, with significant implications for Alzheimer'sFormula:C28H31N3O4Colore e forma:SolidPeso molecolare:473.56β-Amyloid (29-40)
CAS:β-Amyloid (29-40) is a fragment of Amyloid-β peptide.Alzheimer's beta amyloid peptide (29-40/42) C-terminal fragments have physical and chemical propertiesFormula:C49H88N12O13SPurezza:98%Colore e forma:SolidPeso molecolare:1085.36p-HTAA
CAS:<p>Pentamer Hydrogen Thiophene Acetic Acid (p-HTAA) is a compound that specifically targets and labels amyloid-beta (Aβ) deposits in the brains of living mice [1].</p>Formula:C24H16O4S5Colore e forma:SolidPeso molecolare:528.71β-Amyloid (11-22)
CAS:β-Amyloid (11-22) is a peptide fragment of β-Amyloid.Beta-amyloid peptide (Abeta), the major constituent of amyloid plaques in the brains of Alzheimer’sFormula:C70H102N18O18Purezza:98%Colore e forma:SolidPeso molecolare:1483.677-Deoxy-trans-dihydronarciclasine
CAS:7-Deoxy-trans-dihydronarciclasine is an alkaloid that functions as a tobacco mosaic virus (TMV) inhibitor with an IC50 of 1.80 μM and also serves as an anti-Formula:C14H15NO6Colore e forma:SolidPeso molecolare:293.27δ-secretase inhibitor 11
CAS:<p>δ-secretase inhibitor 11 is an inhibitor of δ-secretase and can be used as a lead compound for translational development of AD treatment.</p>Formula:C10H12N4O2Purezza:99.84%Colore e forma:SolidPeso molecolare:220.23BSB
CAS:BSB is a Congo red-derived fluorescent probe, an amyloid protein imaging agent, interacting with amyloid fibrils formed by Aβ (1-40) peptides in rodents.Formula:C24H17BrO6Purezza:95.53%Colore e forma:SolidPeso molecolare:481.29CHF-5022
CAS:CHF-5022 is a nonsteroidal anti-inflammatory drug that selectively inhibits the production of beta-amyloid protein (1-42) (ABETA42).Formula:C17H12F4O2Colore e forma:SolidPeso molecolare:324.272,3-Dehydrosilybin A
CAS:2,3-Dehydrosilybin A is a useful organic compound for research related to life sciences and the catalog number is T125202.Formula:C25H20O10Colore e forma:SolidPeso molecolare:480.435-FAM-β-Amyloid (1-28)
5-FAM-β-Amyloid (1-28) is a fluorescently-labeled peptide corresponding to the first 28 amino acids of the β-Amyloid protein.Formula:C166H219N41O52Colore e forma:SolidPeso molecolare:3620.76β-Amyloid (1-17)
CAS:This synthetic peptide consists of amino acids 1 to 17 of beta amyloid protein. This peptide can be employed in beta amyloid solubility studies.Formula:C90H130N28O29Purezza:98%Colore e forma:SolidPeso molecolare:2068.2Sabirnetug
CAS:<p>Sabirnetug is a humanized IgG2κ monoclonal antibody that specifically targets the amyloid-β (A4) precursor protein.</p>Colore e forma:LiquidSQ-3
SQ-3, a quinoline analogue, prefers α-syn (Ki=39.3nM) to Aβ (Ki=230nM), and [18F]SQ3 is a lead for α-syn probes. [1]Formula:C21H21FN2OColore e forma:SolidPeso molecolare:336.4Davunetide
CAS:<p>Davunetide: neuroprotective 8-amino acid peptide, improves daily function in schizophrenia, boosts memory in mild cognitive impairment.</p>Formula:C36H60N10O12Purezza:98%Colore e forma:SolidPeso molecolare:824.92BIBD-124
CAS:BIBD-124, with an IC50 value of 9.51 nM, effectively binds to amyloid beta (Aβ) plaques.Formula:C19H24FN3O3Colore e forma:SolidPeso molecolare:361.41β-Amyloid (1-34)
CAS:This is a fragment of beta-amyloid peptide. It has amino acids 1 through 34.Formula:C170H253N47O52Purezza:98%Colore e forma:SolidPeso molecolare:3787.2β-Amyloid (1-20)
CAS:<p>This synthetic peptide consists of amino acids 1 to 20 of beta amyloid protein.</p>Formula:C113H157N31O32Purezza:98%Colore e forma:SolidPeso molecolare:2461.7β-Amyloid (12-20)
CAS:β-Amyloid (12-20) is a peptide fragment of β-Amyloid.Thsis peptide contain the amino acid residues VFF at position (18-20), suggesting that this triad hasFormula:C57H83N15O11Purezza:98%Colore e forma:SolidPeso molecolare:1154.36β-Amyloid (35-42)
CAS:β-Amyloid (35-42) is a peptide derived from the beta-amyloid protein, encompassing amino acids 35 through 42.Formula:C33H60N8O9SPurezza:98%Colore e forma:SolidPeso molecolare:744.94β-Amyloid (1-9)
CAS:<p>This is an N-terminal fragment of beta amyloid.</p>Formula:C42H60N14O17Purezza:98%Colore e forma:SolidPeso molecolare:1033.01AC 253
CAS:Amylin (AMY3) receptor antagonist; blocks cAMP, Ca2+, PKA, MAPK, Akt, and cFOS activity; prevents Aβ-induced neuronal death. Cyclic AC 253 variant exists.Formula:C122H196N40O39Purezza:98%Colore e forma:SolidPeso molecolare:2847.11Amyloid β Peptide (42-1)(human) acetate
<p>Amyloid β Peptide (42-1)(human) acetate is the inactive form of Amyloid β Peptide (1-42).</p>Purezza:95.20%Colore e forma:Soildβ-Amyloid (18-28)
CAS:Intracerebroventricular administration of synthetic peptides Beta-amyloid (12-20), (12-28), and (18-28) causes amnesia in mice.Formula:C55H81N13O18Purezza:98%Colore e forma:SolidPeso molecolare:1212.31β-Amyloid (1-11)
CAS:Anionic interaction of Beta-amyloid (1-11) with Factor XII is suspected to cause massive activation of the C4 (complement 4) system in the cerebrospinal fluidFormula:C56H76N16O22Purezza:98%Colore e forma:SolidPeso molecolare:1325.3Amyloid-β-IN-1
Amyloid-β-IN-1 (compound 13), a synthetic peptide featuring the hydrophobic C-terminal segment "VVIA-NH2" and its reversed sequence "AIVV-NH2" derived from Aβ 42, acts as an Aβ inhibitor. It effectively inhibits Aβ aggregation and exhibits neuroprotective effects.Formula:C18H35N5O4Peso molecolare:385.5Aβ-IN-7
Aβ-IN-7 (compound 5a) acts as a potent inhibitor of Aβ aggregation, stabilizing Aβ monomers at 50 μM concentration to prevent them from forming larger oligomersFormula:C14H10N2SColore e forma:SolidPeso molecolare:238.31Aβ-IN-8
Aβ-IN-8, also known as compound 7e, is a potent inhibitor of Aβ aggregation [1].Formula:C22H16F3N3O3SColore e forma:SolidPeso molecolare:459.44DDC 2′,3′-O-disulfate
DDC 2′,3′-O-disulfate (compound 4) inhibits the fibrillization and oligomerization of Aβ42, showing promise for Alzheimer's disease (AD) research [1].Formula:C17H16O11S2Colore e forma:SolidPeso molecolare:460.43AZD4694 Precursor
CAS:AZD4694 Precursor used for synthesizing [18F]AZD4694, a high-affinity amyloid-β imaging agent.Formula:C22H25N3O7Colore e forma:SolidPeso molecolare:443.45BTA-EG4 hydrate
CAS:BTA-EG4 hydrate aids in diagnosing and mitigating Alzheimer's, enhancing cognitive abilities.Formula:C22H28N2O4SColore e forma:SolidPeso molecolare:416.53Anti-Amyloid β Antibody (scFv59)
Anti-Amyloid Beta Antibody (scFv59) is a human-derived antibody produced in CHO cells that targets Amyloid-β. For isotype control, please refer to Human IgG1 kappa, Isotype Control.Colore e forma:Odour Liquid(Gln22)-Amyloid β-Protein (1-42)
CAS:(Gln22)-Amyloid β-Protein (1-42), a Dutch mutation (E22Q) variant of β-Amyloid (1-42), demonstrates increased fibrillogenic and pathogenic characteristics [1].Formula:C203H312N56O59SColore e forma:SolidPeso molecolare:4513.05SLAFVDVLN
SLAFVDVLN is a peptide molecule that functions as a BACE-1 inhibitor, exhibiting a Ki value of 94 nM. Additionally, SLAFVDVLN is capable of reducing the production of Aβ42.Formula:C45H72N10O14Colore e forma:SolidPeso molecolare:977.11Amyloid β-Protein (3-42)
CAS:Amyloid β-Protein (3-42), the precursor of Pyr peptide, serves as the foundation of the amyloid template block in Alzheimer's disease when modified toColore e forma:Solid(Met(O2)35)-Amyloid β-Protein (1-42)
(Met(O2)35)-Amyloid β-Protein (1-42) is a peptide [1] .Formula:C203H311N55O62SColore e forma:SolidPeso molecolare:4546.04(Met(O)35)-Amyloid β-Protein (1-42)
<p>(Met(O)35)-Amyloid β-Protein (1-42) represents the oxidized form of Methionine 35 in Aβ42, capable of producing an oligomer size distribution akin to that of</p>Formula:C203H311N55O61SColore e forma:SolidPeso molecolare:4530.04mcK6A1
<p>mcK6A1 serves as an inhibitor of amyloid-β (Aβ) aggregation, selectively binding to the 16KLVFFA21 fragment of Aβ42, leading to the formation of an extended β-sheet structure and preventing the formation of Aβ42 oligomers. This compound is valuable for research into Alzheimer's disease and other amyloid-related disorders.</p>Formula:C71H99N17O16Colore e forma:SolidPeso molecolare:1446.65Biotin-β-Amyloid (1-42), human TFA
Biotin-β-Amyloid (1-42), human TFA, also known as Biotin-Amyloid β-Peptide (1-42) (human) TFA, is a biotin-labeled 42-amino acid peptide implicated in theFormula:C215H326F3N57O64S2Colore e forma:SolidPeso molecolare:4854.36Biotinoyl tripeptide-1
CAS:Biotinoyl tripeptide-1 can produce hair follicles by promoting scalp micro-circulation and reduce follicle atrophy and aging.Formula:C24H38N8O6SPurezza:98%Colore e forma:SolidPeso molecolare:566.67Vanutide cridificar
CAS:Vanutide cridificar (ACC-001) is an aminoterminal Aβ1-7 peptide conjugate, employed in Alzheimer’s disease (AD) research [1].Colore e forma:Liquidβ-Amyloid (1-43)(human) TFA
β-Amyloid (1-43)(human) TFA exhibits greater aggregation tendencies and heightened toxicity compared to its well-established counterpart, Aβ1-42.Formula:C209H319F3N56O64SColore e forma:SolidPeso molecolare:4729.21β-Amyloid (1-38), mouse, rat
CAS:β-Amyloid (1-38), derived from mice and rats, is a chemical compound comprising 38 amino acids, specifically residues 1-38 of the Aβ peptide.Colore e forma:SolidE3 ligase Ligand 41
CAS:E3 Ligase Ligand 41 (Compound SI-13) serves as a ligand for the E3 ubiquitin ligase DCAF16. It is designed to connect with SLF through a linker, enabling the formation of KB03-SLF.Formula:C13H12ClF3N2O4Colore e forma:SolidPeso molecolare:352.69FITC-β-Ala-Amyloid β-Protein (1-42) (ammonium)
FITC-β-Ala-Amyloid β-Protein (1-42) (ammonium) is a FITC-labeled amyloid beta monomer, Alzheimer’s research, drug screening, and biomolecular studies.Formula:C227H330N58O66S2Colore e forma:SolidPeso molecolare:4991.53Acetyl-Tau Peptide (273-284) amide
CAS:Acetyl-Tau Peptide (273-284) amide inhibits Ac-Aβ(25–35)-NH2 aggregation and models Aβ/Tau interaction.Formula:C64H116N18O17Colore e forma:SolidPeso molecolare:1409.72(D-Asp1)-Amyloid β-Protein (1-42)
CAS:(D-Asp1)-Amyloid β-Protein (1-42), a peptide fragment of amyloid β-protein (Aβ), serves as the primary constituent of vascular and parenchymal amyloid depositsFormula:C203H311N55O60SColore e forma:SolidPeso molecolare:4514.04(Glu20)-Amyloid β-Protein (1-42)
CAS:<p>(Glu20)-Amyloid β-Protein (1-42) represents a variant of amyloid β-protein (Aβ) that fibrillizes more slowly.</p>Formula:C199H309N55O62SColore e forma:SolidPeso molecolare:4495.98G923-0271
CAS:<p>G923-0271 is a TDP-43 inhibitor that improves disease phenotypes in TDP-43 nematode models and reduces the overexpression of human TDP-43, ALS FTD.</p>Formula:C28H23FN4OColore e forma:SolidPeso molecolare:450.51Amyloid-Forming peptide GNNQQNY
CAS:Amyloid-Forming peptide GNNQQNY, a biologically active heptapeptide derived from the N-terminal prion-determining domain of yeast Sup35, is instrumental inFormula:C33H48N12O14Colore e forma:SolidPeso molecolare:836.81Dalidnetug
CAS:<p>Dalidnetug is a humanized monoclonal antibody that targets human β-amyloid precursor protein (APP). By specifically binding to APP, Dalidnetug reduces the production of β-amyloid (Aβ), thereby demonstrating activity in clearing β-amyloid. This compound holds potential for research in Alzheimer's disease.</p>Colore e forma:LiquidY040-7904
Y040-7904 is a potential mitochondrial autophagy activator. It enhances mitochondrial autophagy by facilitating the transport of mitochondria to autophagosomes and promoting the fusion of autophagosomes with autolysosomes. Y040-7904 induces mitochondrial autophagy through the SIRT1/FoxO3 pathway and upregulates the levels of Parkin, PINK1, and LC3II/I. Additionally, Y040-7904 reduces Aβ accumulation in both in vitro and in vivo Alzheimer's disease models.Colore e forma:Odour SolidAβ1-14-εK-KKK-MvF5 Th
<p>Aβ1-14-εK-KKK-MvF5 Th (UB311 immunogen I) is a biologically active peptide and one of the Aβ1–14 targeting peptides (B-cell epitope) used in UB-311.</p>Formula:C199H318N56O55Peso molecolare:4372.38081Amyloid β-Protein (1-24)
CAS:Amyloid β-Protein (1-24) is a peptide identified through peptide screening. This tool predominantly employs immunoassays to gather and analyze active peptides. Peptide screening is utilized in studies involving protein interactions, functional analysis, and epitope screening, particularly relevant in the research and development of active molecules.Formula:C130H183N35O40Peso molecolare:2876.05β-Amyloid (35-25)
CAS:β-Amyloid (35-25) is the reverse sequence of β-Amyloid (25-35).Formula:C45H81N13O14SPeso molecolare:1060.27FITC-β-Ala-Amyloid β-Protein (1-42)
CAS:FITC-β-Ala-Amyloid β-Protein (1-42) is a polypeptide identified through peptide screening. This screening method predominantly utilizes immunoassays to gather active polypeptides and is used in studying protein interactions, conducting functional analyses, and screening antigen epitopes, with particular application in the research and development of active molecules.Formula:C227H327N57O66S2Peso molecolare:4971.34251BSBM6
CAS:BSBM6 is an inhibitor of Aβ aggregation and neuronal toxicity that acts by reversing the aggregation and toxicity of amyloid-β peptides.Formula:C23H29N3O5Purezza:98%Colore e forma:SolidPeso molecolare:427.49SCH-900229
CAS:SCH-900229, a potent presenilin 1 selective γ-secretase inhibitor, used to treat Alzheimer’s Disease.Formula:C21H21ClF2O6S2Colore e forma:SolidPeso molecolare:506.972002-H20
CAS:2002-H20 is an Aβ42-induced cytotoxicity inhibitor. It acts by binding the Alzheimer's Aβ peptide and reducing its cytotoxicity.Formula:C20H15N3O3Purezza:98%Colore e forma:SolidPeso molecolare:345.358Biphenyl-3′,3,4,4′-tetrol
CAS:Biphenyl-3′,3,4,4′-tetrol (BPT) is a potent inhibitor of Aβ40 aggregation and can be utilized in research related to neurodegenerative diseases such as Alzheimer's.Formula:C12H10O4Colore e forma:SolidPeso molecolare:218.21JNK3 inhibitor-9
<p>JNK3inhibitor-9 (Compound 24a) is a potent, selective JNK3 inhibitor capable of crossing the blood-brain barrier (BBB), demonstrating an IC50 value of 12 nM. It effectively inhibits GSK3α/β, which is involved in Tau phosphorylation, with IC50 values of 14 nM and 35 nM, respectively. JNK3inhibitor-9 also reduces the phosphorylation of c-Jun and APP and protects neurons from Aβ1-42 toxicity.</p>Formula:C25H27N7O2Colore e forma:SolidPeso molecolare:457.528Glycerophosphorylethanolamine (sodium salt)
CAS:<p>Glycerophosphorylethanolamine, a phosphatidylethanolamine metabolite, elevates in Alzheimer's and promotes Aβ40 aggregation.</p>Formula:C5H13NNaO6PColore e forma:SolidPeso molecolare:237.12LPYFD-NH2
CAS:neuroprotective peptide that binds to amyloid beta (Aβ)Formula:C33H44N6O8Purezza:98%Colore e forma:SolidPeso molecolare:652.74β-Amyloid (22-35)
CAS:β-Amyloid (22-35) is a 14-aa peptide, shows aggregates and induces neurotoxicity in the hippocampal cells.Formula:C59H102N16O21SPurezza:98%Colore e forma:SolidPeso molecolare:1403.62β-Amyloid (22-40)
CAS:This synthetic peptide consists of amino acids 22 to 40 of beta amyloid protein.Formula:C78H135N21O26SPurezza:98%Colore e forma:SolidPeso molecolare:1815.1SEN177
CAS:<p>SEN177 shows the potential in the research of Huntington's disease that is a potent inhibitor of glutaminyl cyclase (QPCT) with an IC 50 of 0.013μM for glutaminyl-peptide cyclotransferase-like (QPCTL). The Ki value of SEN177 for human glutaminyl cyclase (hQC) is 20 nM. SEN177 significantly reduces the early stages of mutant HTT oligomerisation and reduces the percentage of neurons with Q80 aggregates [1].</p>Formula:C18H19FN6Colore e forma:SolidPeso molecolare:338.38TH-237A
CAS:TH-237A is a novel neuroprotective agent exhibiting favorable permeation across the blood-brain barrier.Formula:C18H17F2NO3Purezza:98%Colore e forma:SolidPeso molecolare:333.335AZD4694
CAS:Flutafuranol (AZD4694/NAV4694) binds beta-amyloid, potential PET tracer for Alzheimer's. Non-F18 version supplied.Formula:C14H11FN2O2Colore e forma:SolidPeso molecolare:258.25(Rac)-Z-Phe-Phe-FMK
CAS:(Rac)-Z-Phe-Phe-FMK (Cathepsin L-IN-2) is a cathepsin L inhibitor that inhibits the tendency of β-amyloid to induce apoptotic changes .Formula:C27H27FN2O4Purezza:98.27%Colore e forma:SolidPeso molecolare:462.51Cu(II)GTSM
CAS:Cu(II)GTSM is a cell permeable copper complex inhibits GSK3β activity and suppresses levels of neurotoxic amyloid β-trimers and phosphorylated tau.Formula:C6H10CuN6S2Purezza:99.21%Colore e forma:SolidPeso molecolare:293.86Begacestat
CAS:Begacestat (GSI-953) is a potent and selective gamma-secretase inhibitor that inhibits Amyloid-beta, inhibits cleavage of APP,,Alzheimer's disease.Formula:C9H8ClF6NO3S2Colore e forma:SolidPeso molecolare:391.74PiB
CAS:<p>PiB (Pittsburgh Compound-B) is a standard for analysis of 11C-PiB. 11C-PiB is a β-amyloid PET imaging tracer for Alzheimer's disease diagnosis.</p>Formula:C14H12N2OSPurezza:97.02%Colore e forma:SolidPeso molecolare:256.32EUK-134
CAS:EUK-134, a synthetic SOD/catalase mimetic, exhibits potent antioxidant activities, and inhibits the formation of β-amyloid and related amyloid fibril.Formula:C18H18ClMnN2O4Purezza:98.39%Colore e forma:SolidPeso molecolare:416.74Dihydroergocristine mesylate
CAS:DHEC mesylate is a vasodilator and α-adrenergic antagonist used for vascular dementia and as a geroprotector.Formula:C36H45N5O8SPurezza:98.9% - 99.79%Colore e forma:SolidPeso molecolare:707.84PBD-150
CAS:PBD-150 is an inhibitor of human glutaminyl cyclase (hQC) Y115E-Y117E variant( ki : 490 nM)Formula:C15H20N4O2SPurezza:99.68%Colore e forma:SolidPeso molecolare:320.41ARN2966
CAS:ARN2966 is an inhibitor of amyloid precursor protein (APP)and amyloid-β (Aβ) secretion.Formula:C12H12N2OPurezza:99.52% - 99.86%Colore e forma:SolidPeso molecolare:200.24Cromoglicic acid
CAS:<p>Cromoglicic acid prevents the release of inflammatory chemicals such as histamine from mast cells.</p>Formula:C23H16O11Purezza:99.55% - >99.99%Colore e forma:Colorless Crystals From Ethanol + Ether Physical Description Solid (Ntp 1992)Peso molecolare:468.37Benzenesulfonamide
CAS:Benzenesulfonamide (Benzosulfonamide) ia an inhibitor of carbonic anhydrases.Formula:C6H7NO2SPurezza:99.42% - 99.99%Colore e forma:White Crystalline PowderPeso molecolare:157.19CRANAD 2
CAS:<p>CRANAD-2, a near-infrared probe, detects amyloid-beta in vivo, increasing fluorescence 70x and shifting blue 90 nm upon binding.</p>Formula:C23H25BF2N2O2Purezza:99.44%Colore e forma:Dark Blue To Black PowderPeso molecolare:410.27Anle138b
CAS:Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson's diseaseFormula:C16H11BrN2O2Purezza:98.88% - 99.82%Colore e forma:SolidPeso molecolare:343.17PE859
CAS:<p>PE859 is a potent inhibitor of both tau and Aβ aggregation.</p>Formula:C28H24N4O2Purezza:98.8% - 99.09%Colore e forma:SolidPeso molecolare:448.521,1'-Methylenedi-2-naphthol
CAS:<p>1,1'-Methylenedi-2-naphthol target CYP2C19 - cytochrome P450 family 2 subfamily C member 19 (human).</p>Formula:C21H16O2Purezza:98.91%Colore e forma:Light Pink To Light Brown Crystalline PowderPeso molecolare:300.35MK-0752
CAS:<p>MK-0752, a γ-secretase inhibitor, reduces Aβ40 production(IC50=5 nM).</p>Formula:C21H21ClF2O4SPurezza:98% - 99.55%Colore e forma:SolidPeso molecolare:442.9TAE-1
CAS:<p>TAE-1 is an inhibitor of amyloid-β fibril formation and aggregation. It inhibits cholinesterases AChE and BuChE with IC50 of 0.3 μM and 3.9 μM, respectively.</p>Formula:C39H51I3N6O9Purezza:94.58%Colore e forma:SolidPeso molecolare:1128.57RO4929097
CAS:<p>RO4929097 (RG-4733), a γ secretase inhibitor (IC50: 4 nM), inhibits cellular processing of Aβ40 and Notch (EC50: 14/5 nM).</p>Formula:C22H20F5N3O3Purezza:98.5% - 99.51%Colore e forma:SolidPeso molecolare:469.4Frentizole
CAS:<p>Frentizole, an immunosuppressive agent, is an inhibitor of the Aβ-ABAD interaction</p>Formula:C15H13N3O2SPurezza:99.82%Colore e forma:SolidPeso molecolare:299.35Azeliragon
CAS:Azeliragon (TTP488) is an antagonist at the Receptor for Advanced Glycation End products; is evaluated as a potential treatment for patients with mild-to-Formula:C32H38ClN3O2Purezza:96.7% - 98.33%Colore e forma:SolidPeso molecolare:532.12Semax acetate(80714-61-0 free base)
CAS:Semax acetate is a synthetic peptide analog of adrenocorticotropic hormone (ACTH) that has neuroprotective, analgesic, and anxiolytic properties.Formula:C39H55N9O12SPurezza:99.46%Colore e forma:SolidPeso molecolare:873.98Semagacestat
CAS:Semagacestat (LY450139) (LY450139) is a γ-secretase blocker for Aβ42/Aβ40/Aβ38 (IC50: 10.9/12.1/12.0 nM) and also inhibits Notch signaling (IC50: 14.1 nM).Formula:C19H27N3O4Purezza:97.1% - 99.9%Colore e forma:SolidPeso molecolare:361.44FPS-ZM1
CAS:FPS-ZM1 is a high-affinity RAGE specific inhibitor that blocks Aβ binding to the V domain of RAGE.Formula:C20H22ClNOPurezza:99.32% - 99.52%Colore e forma:SolidPeso molecolare:327.85Miridesap
CAS:<p>Miridesap (GSK2315698) rapidly depletes SAP in blood, cerebrospinal fluid, and amyloid deposits via liver clearance.</p>Formula:C16H24N2O6Purezza:≥95%Colore e forma:SolidPeso molecolare:340.37Aftin-4
CAS:Aftin-4, an amyloid forty-two inducer, activates γ-secretase, promoting the generation of amyloid-β-1-42 (Aβ1-42) from amyloid-β protein precursor.Formula:C20H28N6OPurezza:98.51%Colore e forma:SolidPeso molecolare:368.48Azeliragon HCl
CAS:Azeliragon: potent oral RAGE inhibitor, blocks Alzheimer's-linked amyloid brain entry.Formula:C32H40Cl3N3O2Colore e forma:SolidPeso molecolare:605.04Edonerpic maleate
CAS:Edonerpic maleate (T-817 maleate) is a neurotrophic agent which can inhibit amyloid-β peptides (Aβ).Formula:C20H25NO6SPurezza:98.24%Colore e forma:SolidPeso molecolare:407.48Pyridoxal 5'-phosphate hydrate
CAS:Pyridoxal 5'-phosphate hydrate (PLP)(1:x), the active form of vitamin B6, is a cofactor for many different enzymes involved in transamination reactions,Formula:C8H10NO6PPurezza:97.52%Colore e forma:SolidPeso molecolare:247.14JLK6
CAS:JLK6 was a gamma-secretase inhibitor that does not interfere with Notch signallingFormula:C10H8ClNO3Purezza:96.50%Colore e forma:SolidPeso molecolare:225.63γ-Secretase modulator 13
CAS:γ-Secretase modulator 13 is a γ-secretase modulator (GSMs) that can be used to study Alzheimer's disease and tumors.Formula:C22H23FN6SPurezza:99.79%Colore e forma:SolidPeso molecolare:422.52Solanezumab
CAS:<p>Solanezumab (LY 2062430) is a monoclonal antibody that binds preferentially to soluble amyloid and promotes its clearance from the brain.</p>Purezza:96.3% (SDS-PAGE); 97.5% (SEC-HPLC) - 96.3% (SDS-PAGE); 97.5% (SEC-HPLC)Colore e forma:LiquidPeso molecolare:144.1 (kDa)4-Hydroxyindole
CAS:4-Hydroxyindole: aromatic, antioxidant, used in cancer treatment and preventing neurodegenerative diseases.Formula:C8H7NOPurezza:97.05% - 98.13%Colore e forma:Off-White Cyrstalline SolidPeso molecolare:133.15Remternetug
CAS:<p>Remternetug is a humanized IgG1-kappa monoclonal antibody that targets the N3pGlu peptide of the amyloid beta A4 precursor protein (APP) Aβ42.</p>Purezza:95% - 95%Colore e forma:LiquidDezamizumab
CAS:Dezamizumab is a humanized antibody targeting the serum amyloid P component (SAP) to clear amyloid fibrils via macrophage phagocytosis, for research in systemic amyloid diseases.Purezza:95% - 98.2% (SDS-PAGE); 98.7% (SEC-HPLC)Colore e forma:LiquidBapineuzumab
CAS:Bapineuzumab (AAB-001) is a humanised monoclonal antibody targeting amyloid-beta (Aβ), soluble and oligomeric forms of amyloid β, Alzheimer's disease (AD).Purezza:95%Colore e forma:LiquidHomotaurine-d6
CAS:<p>Homotaurine-d6 is a deuterated compound of Homotaurine. Homotaurine has a CAS number of 3687-18-1. Because of its similarity in structure to the neurotransmitter gamma-aminobutyric acid (GABA), it has GABAergic effects and may be useful as an anticonvulsant. Homotaurine has also been investigated as a potential treatment for Alzheimer's disease. It binds to soluble amyloid beta and inhibits the formation of neurotoxic aggregates that lead to amyloid plaque deposition in the brain. However, clinical trials failed to show improvement compared to placebo.</p>Formula:C3D6H3NO3SColore e forma:SolidPeso molecolare:145.21Nicardipine pyridine metabolite II
CAS:<p>Nicardipine pyridine metabolite II is a biaoctive chemical.</p>Formula:C26H27N3O6Colore e forma:SolidPeso molecolare:477.514-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine
CAS:4-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine is a potent amyloid imaging agent that binds to Amyloid-β (1-40) (KD: 1.7 nM).Formula:C14H11BrN2SPurezza:98%Colore e forma:SolidPeso molecolare:319.22Aftin-5
CAS:Aftin-5 is an inducer of amyloid beta protein 42 (Aβ42). It functions by modifying the ultrastructure of mitochondria, leading to an upregulation of Aβ42 and a downregulation of Aβ38 through a β-secretase and γ-secretase-dependent mechanism. Aftin-5 exhibits mild cytotoxicity in SH-SY5Y, HT22, N2a, and N2a-AβPP695 cells, with IC50 values of 180, 194, 178, and 150 μM, respectively.Formula:C19H26N6OColore e forma:SolidPeso molecolare:354.45Eprodisate
CAS:Eprodisate disrupts protein-glycosaminoglycan binding, halting amyloid fibril formation, potentially delaying AA amyloidosis progression.Formula:C3H8O6S2Colore e forma:SolidPeso molecolare:204.224-(6-Bromo-2-benzothiazolyl)benzenamine
CAS:4-(6-Bromo-2-benzothiazolyl)benzenamine is a β-amyloid PET tracer and can be used in the diagnosis of neurological diseases.Formula:C13H9BrN2SPurezza:98%Colore e forma:SolidPeso molecolare:305.19KMS88009
CAS:KMS88009 is an amyloid-β aggregation inhibitor that acts by ameliorating neurodegenerative disorder.Formula:C19H19NO2Colore e forma:SolidPeso molecolare:293.36JNJ-40418677
CAS:JNJ-40418677 is a γ-secretase modulator that selectively blocks γ-site cleavage of the APP without affecting the processing of Notch.Formula:C26H22F6O2Purezza:98%Colore e forma:SolidPeso molecolare:480.44SEN-1269
CAS:SEN-1269 prevents amyloid-β aggregation, shields neurons, and improves memory by hindering Aβ(1-42)-induced issues.Formula:C18H18N4O2Purezza:98%Colore e forma:SolidPeso molecolare:322.36γ-Secretase modulator 12
CAS:γ-Secretase modulator 12 (Compound 1a) is a selective compound that effectively reduces amyloid-β42 (Aβ42) levels with an IC50 of 0.39 μM.Formula:C25H23N3O2Colore e forma:SolidPeso molecolare:397.47Caprospinol
CAS:Caprospinol inhibits β-Amyloid (Aβ) protein neurotoxicity.Formula:C33H52O4Purezza:98%Colore e forma:SolidPeso molecolare:512.76THK-523
CAS:THK-523 selectively binds to tau in Alzheimer's, potent in vitro/vivo. 18F-THK523 excels in tau imaging.Formula:C17H15FN2OColore e forma:SolidPeso molecolare:282.31BACE1/2-IN-1
CAS:BACE1/2-IN-1 inhibits BACE1/2 with IC50s of 0.01μM/0.0053μM, has better permeability and lower Pgp efflux but reduced metabolic stability.Formula:C21H31N5OSColore e forma:SolidPeso molecolare:401.57AY1511
CAS:AY1511 is a low cytotoxic inhibitor of amyloid β (Aβ) aggregation [1].Formula:C17H14O6Colore e forma:SolidPeso molecolare:314.29AZ4800
CAS:AZD4800 is a gamma secretase modulators.Formula:C24H29N5O3Colore e forma:SolidPeso molecolare:435.52Glutaminyl Cyclase Inhibitor 2
CAS:Glutaminyl Cyclase Inhibitor 2 is a glutaminyl cyclase inhibitor (IC50: 1.23 μM).Formula:C19H20FN3Purezza:98%Colore e forma:SolidPeso molecolare:309.38Antioxidant agent-2
CAS:Antioxidant agent-2 (3c), BBB-permeable, selectively chelates metals; shows neuroprotection, fights liver damage in Alzheimer's research.Formula:C23H26N2O7Colore e forma:SolidPeso molecolare:442.46SV5
CAS:SV5: potent anti-Alzheimer's, protects SHSY-5Y from Aβ1-42 death, stable with optimal pharmacology in plasma, antioxidant, neuroprotective.Formula:C21H30N2O4S2Colore e forma:SolidPeso molecolare:438.6Aβ Fibrillization modulator 1
CAS:Aβ Fibrillization Modulator 1 stabilizes amyloid-beta (Aβ) monomers, preventing their aggregation into fibrils.Formula:C17H12N4O3SSeColore e forma:SolidPeso molecolare:431.33Chrysamine G
CAS:Chrysamine G, Congo red analog, blocks Aβ toxicity, probes Alzheimer's amyloid.Formula:C26H16N4Na2O6Colore e forma:SolidPeso molecolare:526.416K 01-162
CAS:K 01-162 binds and destabilizes AβO (β-amyloid), with an EC50 of 80 nM.Formula:C15H14BrNColore e forma:SolidPeso molecolare:288.18YIAD-0205
CAS:YIAD-0205, an orally administered inhibitor of Aβ(1-42) aggregation, has exhibited in vivo efficacy in a 5XFAD transgenic mouse model that harbors five familialFormula:C26H16Br2ClN3Colore e forma:SolidPeso molecolare:565.69BChE-IN-8
CAS:<p>BChE-IN-8, compound 20, is a potent oral BChE inhibitor effective on eqBChE and hBChE, crosses blood-brain barrier, and may help in Alzheimer's research.</p>Formula:C18H12BrN7O2Colore e forma:SolidPeso molecolare:438.24q-FTAA
CAS:q-FTAA targets Aβ1-42 fibrils (330-630 nM) and ADPBC (300-500 nM), useful in Alzheimer's disease research.Formula:C21H14O6S4Colore e forma:SolidPeso molecolare:490.59Glutaminyl Cyclase Inhibitor 5
Glutaminyl Cyclase Inhibitor 5 is a potent, selective inhibitor of human glutaminyl cyclase (hQC), demonstrating an inhibition concentration half-max (IC 50) ofFormula:C22H30N6OColore e forma:SolidPeso molecolare:394.51OAB-14
CAS:OAB-14, a Bexarotene derivative, enhances β-amyloid clearance and cognitive function in APP/PS1 mice, improving Alzheimer's symptoms.Formula:C32H46N4O2Colore e forma:SolidPeso molecolare:518.73Astrophloxine
CAS:<p>Astrophloxine is a fluorescent imaging probe that targets antiparallel dimers.Astrophloxine can be used to detect aggregated Aβ in brain tissue and</p>Formula:C27H33IN2Purezza:99.89%Colore e forma:SolidPeso molecolare:512.47TC-E 5006
CAS:γ-secretase modulatorFormula:C29H29F4NO2Purezza:98%Colore e forma:SolidPeso molecolare:499.54TML-6
CAS:TML-6, an oral derivative of curcumin, may help in Alzheimer's research by targeting amyloid production and various molecular pathways.Formula:C30H37NO7Purezza:99.71%Colore e forma:SolidPeso molecolare:523.62BuChE-IN-2
CAS:BuChE-IN-2 inhibits BuChE (IC50: 1.28 μM), NO (0.67 μM), Aβ, ROS, chelates Cu2+, penetrates BBB, used in Alzheimer's research.Formula:C28H20F4N6O3Colore e forma:SolidPeso molecolare:564.49RU-505
CAS:RU-505 is an interaction inhibitor of Aβ-fibrinogen that acts by rescuing altered thrombosis and cognitive decline in Alzheimer's disease mice.Formula:C28H32FN5OPurezza:98%Colore e forma:SolidPeso molecolare:473.58ELND006
CAS:ELND006, an oral Alzheimer's drug, has improved bioavailability as a nanosuspension, and food doesn't affect it.Formula:C20H14F5N3O2SColore e forma:SolidPeso molecolare:455.4RS-0466
CAS:RS-0466 is an β-amyloid-induced cytotoxicity inhibitor.Formula:C17H17N5O2Purezza:98%Colore e forma:SolidPeso molecolare:323.35LC kinetic stabilizer-2
CAS:LC Kinetic Stabilizer-2 is a powerful stabilizer for amyloidogenic immunoglobulin light chains (LC), demonstrating significant efficacy with an EC50 of 24 nM.Formula:C28H31N3O3Colore e forma:SolidPeso molecolare:457.56Neuroinflammatory-IN-2
CAS:Neuroinflammatory-IN-2: anti-neuroinflammatory, inhibits MAO-B (IC50: 10.30µM), 96.33% Aβ1-42 aggregation reduction, neuroprotective in PC-12 cells.Formula:C25H27FN2O3Colore e forma:SolidPeso molecolare:422.49MK-3328
CAS:<p>MK-3328, a potential Alzheimer's drug, binds β-Amyloid with strong affinity (IC50:10.5 nM) and may serve as a PET ligand to gauge plaque load.</p>Formula:C14H9FN4OPurezza:99.70% - >99.99%Colore e forma:SolidPeso molecolare:268.25Ezeprogind disulfate
CAS:Ezeprogind disulfate: neurotrophic inducer targeting neurodegeneration causes like Abeta, tau; for neurological disorder research.Formula:C25H48N6O8S2Purezza:99.72%Colore e forma:SolidPeso molecolare:624.81Buntanetap
CAS:Buntanetap ((+)-Phenserine) is an inhibitor of TINAPs used in the study of neurological disorders, endocrine and metabolic disorders, and cardiovascular diseaseFormula:C20H23N3O2Purezza:98.2%Colore e forma:SolidPeso molecolare:337.42Aβ-IN-1
CAS:Aβ-IN-1 is a novel, potent and orally active γ-secretase modulator (GSM).Formula:C35H49NPurezza:99.1%Colore e forma:SoildPeso molecolare:483.77Glutaminyl Cyclase Inhibitor 1
CAS:Glutaminyl Cyclase Inhibitor 1 is a glutaminyl cyclase inhibitor (IC50: 0.5 μM) that can be used to study neurological disorders.Formula:C21H24FN3O2Purezza:99.81%Colore e forma:SolidPeso molecolare:369.43Aleplasinin
CAS:Aleplasinin (PAZ 417) is a selective and orally active inhibitor of Plasminogen activator inhibitor-1(PAI-1) and a key negative regulator of the fibrinolyticFormula:C28H27NO3Purezza:99.21%Colore e forma:SolidPeso molecolare:425.52PPI-1019
CAS:PPI-1019 is an APP (β-amyloid A4) inhibitor for the treatment of neurological disorders and the study of Alzheimer's disease (AD).Formula:C36H54N6O5Purezza:95.16% - 98.16%Colore e forma:SolidPeso molecolare:650.85BI-1408
CAS:BI-1408 is a modulator potent of γ secretase (IC50: 0.04 μM for Aβ42).Formula:C22H23FN6Purezza:99.63%Colore e forma:SolidPeso molecolare:390.46amyloid P-IN-1
CAS:<p>amyloid P-IN-1 can be used in studies about diseases with depletion of serum amyloid P components such as Alzheimer's disease, amyloidosis, osteoarthritis, and</p>Formula:C30H44N2O14Purezza:99.76%Colore e forma:SolidPeso molecolare:656.68MAO-B-IN-9
CAS:<p>MAO-B-IN-9 is a monoamine oxidase B MAO-B inhibitor (IC50: 0.18 μM) that crosses the blood-brain barrier with potency, selectivity and time-dependence.</p>Formula:C18H24N2O2Purezza:99.93%Colore e forma:SolidPeso molecolare:300.4Fenlean
CAS:"Fenlean (FLZ) in phase I trial at Chinese Academy's Institute of Pharmacy for Parkinson's treatment."Formula:C26H27NO6Purezza:98.99%Colore e forma:SolidPeso molecolare:449.5DSS30
CAS:<p>DSS30 is a P25/CDK5 inhibitor that reduces β-amyloid secretion to help prevent Alzheimer's.</p>Formula:C16H14ClNO3S2Purezza:99.19% - 99.4%Colore e forma:SolidPeso molecolare:367.87rTRD01
CAS:rTRD01 is a TDP-43 ligand that selectively binds to the RRM1 and RRM2 domains of TDP-43, exhibiting a dissociation constant (Kd) of 89 µM for TDP-43 102–269.Formula:C18H21FN4O2Colore e forma:SolidPeso molecolare:344.38TRV-1387
CAS:<p>TRV-1387, a benzofurazan derivative, inhibits the aggregation of tau and amyloid-β [1].</p>Formula:C23H25F3N4O2Colore e forma:SolidPeso molecolare:446.47Anti-amyloid agent-1
CAS:Anti-amyloid agent-1 is a potent compound that inhibits amyloid aggregation, offering a promising approach for research into the treatment of amyloidosis [1].Formula:C21H17F3N2O3Colore e forma:SolidPeso molecolare:402.37QM-FN-SO3
CAS:QM-FN-SO3 is a blood-brain barrier (BBB)-penetrable, near-infrared (NIR) probe with aggregation-induced emission (AIE) activity, specifically designed for the detection of Aβ plaques. It exhibits ultra-high signal-to-noise (S/N) ratio, binding affinity, and high-performance NIR emission, making it suitable for in vivo detection of Aβ plaques [1].Formula:C29H25N4NaO3S2Colore e forma:SolidPeso molecolare:564.65RAGE/SERT-IN-1
CAS:<p>RAGE/SERT-IN-1 is a potent, orally active inhibitor of advanced glycation end products (RAGE) and serotonin transporter (SERT), with IC50 values of 8.26 μM and</p>Formula:C38H41ClN4OSColore e forma:SolidPeso molecolare:637.28NNC 26-9100
CAS:Somatostatin sst4 receptor agonistFormula:C22H25BrCl2N6SPurezza:98%Colore e forma:SolidPeso molecolare:556.35PQM130
CAS:PQM130 is a Feruloyl-Donepezil Hybrid compound against the neurotoxicity induced by Aβ1-42 oligomer (AβO) and shows anti-inflammatory activity.Formula:C23H27NO4Purezza:98.73%Colore e forma:SolidPeso molecolare:381.46QR-0217
CAS:<p>QR-0217 is a potent inhibitor of both Aβ1-40 and α-synuclein aggregation, exhibiting an IC50 of 7.5 µM for Aβ1-40.</p>Formula:C19H13NO3Colore e forma:SolidPeso molecolare:303.31Aβ/tau aggregation-IN-3
CAS:Aβ/tau aggregation-IN-3 is a potent inhibitor of amyloid protein aggregation, exhibiting an IC50 value of 0.85 µM in an Aβ-Thioflavin T (Aβ-ThT) functionalFormula:C23H22N4O3Colore e forma:SolidPeso molecolare:402.45ELND007
CAS:<p>ELND007 is a Gamma secretase inhibitor.</p>Formula:C19H14F4N4O2SColore e forma:SolidPeso molecolare:438.4BMS 433796
CAS:<p>BMS 433796 is a γ-secretase inhibitor that demonstrates Aβ-lowering activity within a transgenic mouse model of Alzheimer's disease.</p>Formula:C21H20F2N4O4Purezza:99.17%Colore e forma:SolidPeso molecolare:430.4γ-Secretase-IN-1
CAS:γ-Secretase-IN-1 is a γ-secretase inhibitor that displays partial antiproliferative activity against T-47D cells.Formula:C27H24F2N4O3Purezza:99.56%Colore e forma:SolidPeso molecolare:490.5MDR-1339
CAS:MDR-1339 is a blood-brain-barrier-permeable inhibitor of amyloid-β (Aβ) aggregation.Formula:C20H22O4Purezza:98.57%Colore e forma:SolidPeso molecolare:326.39Aβ aggregation-IN-1
CAS:Aβ aggregation-IN-1 (Compound 1b) is an inhibitor of amyloid-beta precursor protein. It suppresses the aggregation and disaggregation of amyloid-beta fibrils with IC50 values of 3.92 and 7.19 M, respectively. Additionally, Aβ aggregation-IN-1 reduces malondialdehyde formation in neuronal cells, increases intracellular levels of reduced glutathione (GSH), and inhibits caspase 3.Formula:C9H8BF3O2Colore e forma:SolidPeso molecolare:215.965Anti-Aβ agent 1A
Anti-Aβ agent 1A is a potent anti-amyloid-β agent.Formula:C35H49NO4Colore e forma:SolidPeso molecolare:547.77Glutaminyl Cyclase Inhibitor 3
CAS:Designed anti-Alzheimer’s compound; potent Glutaminyl Cyclase inhibitor; IC50 at 4.5 nM; reduces brain Aβ; improves cognition.Formula:C24H32N6O2SPurezza:98%Colore e forma:SolidPeso molecolare:468.61MAO-B-IN-10
MAO-B-IN-10: Potent, selective MAO-B inhibitor; crosses blood-brain barrier; IC50 5.3 μM; reduces Aβ aggregation 58.2%, disaggregates 43.3%.Formula:C23H26N2O4Colore e forma:SolidPeso molecolare:394.46BF-168
CAS:BF-168 is a candidate probe for PET and specifically recognizes both neuritic and diffuse plaques (Ki: 6.4 nM for Aβ1-42).Formula:C18H17FN2O2Colore e forma:SolidPeso molecolare:312.34
![1H-Indole-3-carboxylic acid, 5-[2-hydroxy-3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]propoxy]…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT67751.webp&w=3840&q=75)
