Beta amiloide
Gli inibitori del beta-amiloide sono composti che mirano specificamente a inibire la formazione o l'aggregazione dei peptidi beta-amiloidi, coinvolti in modo critico nella patogenesi della malattia di Alzheimer. L'accumulo di placche di beta-amiloide nel cervello è uno dei tratti patologici distintivi della malattia, contribuendo alla disfunzione neuronale e al declino cognitivo. Inibendo l'aggregazione del beta-amiloide, questi inibitori sono studiati come potenziali agenti terapeutici per rallentare o prevenire la progressione della malattia di Alzheimer. Presso CymitQuimica, offriamo una gamma di inibitori del beta-amiloide di alta qualità per supportare la tua ricerca nella neurodegenerazione, nell'aggregazione proteica e nella terapia dell'Alzheimer.
Trovati 218 prodotti di "Beta amiloide"
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Glimepiride
CAS:Glimepiride (HOE-490) is a long-acting, third-generation sulfonylurea with hypoglycemic activity.Formula:C24H34N4O5SPurezza:97.84% - 98.87%Colore e forma:White Cyrstalline SolidPeso molecolare:490.62ALZ-801
CAS:ALZ-801, an oral valine-prodrug of tramiprosate, enhances treatment of Alzheimer's by inhibiting β-amyloid aggregation with better PK and tolerance.Formula:C8H18N2O4SPurezza:99.36%Colore e forma:SolidPeso molecolare:238.3Gantenerumab
CAS:Gantenerumab (R-1450) is a humanized antibody targeting amyloid-β (Aβ), used in studies of Alzheimer's disease.Purezza:>95%Colore e forma:LiquidPeso molecolare:146.28Cromolyn sodium
CAS:Cromolyn sodium (FPL-670) is a chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells.Formula:C23H14Na2O11Purezza:99.4% - 99.95%Colore e forma:Colorless Crystals From Ethanol + Ether White Crystalline PowderPeso molecolare:512.33Birtamimab
CAS:<p>Birtamimab (NEOD001) is a monoclonal antibody selectively targeting and depleting amyloid protein, used in research on light chain amyloidosis.</p>Purezza:>95%Colore e forma:LiquidLecanemab
CAS:Lecanemab (BAN-2401) is an IgG1 monoclonal antibody targeting soluble aggregated beta amyloid (Abeta) for the study of cognitive disorders.Purezza:97.3% (SEC-HPLC) - >95.0% (SDS-PAGE); 100% (SEC-HPLC)Colore e forma:LiquidDonanemab
CAS:<p>Donanemab (LY3002813), a humanized IgG1 antibody, targets N-terminal Aβ for potential early Alzheimer's research.</p>Purezza:95%Colore e forma:LiquidLY 2389575 hydrochloride
CAS:LY2389575 hydrochloride is a selective mGlu3 NAM with 190 nM IC50, increases Mrc1, and aids Alzheimer's research.Formula:C15H16BrCl3N4Purezza:99.9%Colore e forma:SolidPeso molecolare:438.58Eprodisate disodium
CAS:Eprodisate disodium (NC-503) is a negatively charged sulfonated inhibitor of fibrillogenesis, that can be used in the treatment of amyloid A (AA) amyloidosis.Formula:C3H6Na2O6S2Purezza:99.88%Colore e forma:White Coarse PowderPeso molecolare:248.19Chlorzoxazone
CAS:Chlorzoxazone (Chlorzoxazon) is a Muscle Relaxant. The physiologic effect of chlorzoxazone is by means of Centrally-mediated Muscle Relaxation.Formula:C7H4ClNO2Purezza:99.49% - 99.6%Colore e forma:SolidPeso molecolare:169.57Aβ-IN-8
Aβ-IN-8, also known as compound 7e, is a potent inhibitor of Aβ aggregation [1].Formula:C22H16F3N3O3SColore e forma:SolidPeso molecolare:459.44BIBD-124
CAS:BIBD-124, with an IC50 value of 9.51 nM, effectively binds to amyloid beta (Aβ) plaques.Formula:C19H24FN3O3Colore e forma:SolidPeso molecolare:361.41β-Amyloid (22-40)
CAS:This synthetic peptide consists of amino acids 22 to 40 of beta amyloid protein.Formula:C78H135N21O26SPurezza:98%Colore e forma:SolidPeso molecolare:1815.1Davunetide
CAS:<p>Davunetide: neuroprotective 8-amino acid peptide, improves daily function in schizophrenia, boosts memory in mild cognitive impairment.</p>Formula:C36H60N10O12Purezza:98%Colore e forma:SolidPeso molecolare:824.92Aβ-IN-7
Aβ-IN-7 (compound 5a) acts as a potent inhibitor of Aβ aggregation, stabilizing Aβ monomers at 50 μM concentration to prevent them from forming larger oligomersFormula:C14H10N2SColore e forma:SolidPeso molecolare:238.31DDC 2′,3′-O-disulfate
DDC 2′,3′-O-disulfate (compound 4) inhibits the fibrillization and oligomerization of Aβ42, showing promise for Alzheimer's disease (AD) research [1].Formula:C17H16O11S2Colore e forma:SolidPeso molecolare:460.43Anti-Amyloid β Antibody (scFv59)
Anti-Amyloid Beta Antibody (scFv59) is a human-derived antibody produced in CHO cells that targets Amyloid-β. For isotype control, please refer to Human IgG1 kappa, Isotype Control.Colore e forma:Odour Liquid2,3-Dehydrosilybin A
CAS:2,3-Dehydrosilybin A is a useful organic compound for research related to life sciences and the catalog number is T125202.Formula:C25H20O10Colore e forma:SolidPeso molecolare:480.43β-Amyloid (10-20)
CAS:Amyloid β-Protein (10-20) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.Amyloid β protein fragment containing the α-Formula:C71H99N17O16Purezza:98%Colore e forma:Lyophilized PowderPeso molecolare:1446.65β-Amyloid (12-28)
CAS:Amyloid β-peptide fragment; minimum section required to bind to brain proteins.Formula:C89H135N25O25Purezza:98%Colore e forma:SolidPeso molecolare:1955.18β-Amyloid (10-35), amide
CAS:β-Amyloid (10-35), amide, is a chemical compound consisting of 26 amino acids, specifically residues 10-35 of the Aβ peptide.Formula:C133H205N35O36SPurezza:98%Colore e forma:SolidPeso molecolare:2902.33CHF-5022
CAS:CHF-5022 is a nonsteroidal anti-inflammatory drug that selectively inhibits the production of beta-amyloid protein (1-42) (ABETA42).Formula:C17H12F4O2Colore e forma:SolidPeso molecolare:324.27β-Amyloid (1-11)
CAS:Anionic interaction of Beta-amyloid (1-11) with Factor XII is suspected to cause massive activation of the C4 (complement 4) system in the cerebrospinal fluidFormula:C56H76N16O22Purezza:98%Colore e forma:SolidPeso molecolare:1325.3β-Amyloid (1-17)
CAS:This synthetic peptide consists of amino acids 1 to 17 of beta amyloid protein. This peptide can be employed in beta amyloid solubility studies.Formula:C90H130N28O29Purezza:98%Colore e forma:SolidPeso molecolare:2068.2Sabirnetug
CAS:<p>Sabirnetug is a humanized IgG2κ monoclonal antibody that specifically targets the amyloid-β (A4) precursor protein.</p>Colore e forma:Liquidβ-Amyloid (22-35)
CAS:β-Amyloid (22-35) is a 14-aa peptide, shows aggregates and induces neurotoxicity in the hippocampal cells.Formula:C59H102N16O21SPurezza:98%Colore e forma:SolidPeso molecolare:1403.625-FAM-β-Amyloid (1-28)
5-FAM-β-Amyloid (1-28) is a fluorescently-labeled peptide corresponding to the first 28 amino acids of the β-Amyloid protein.Formula:C166H219N41O52Colore e forma:SolidPeso molecolare:3620.76Aducanumab
CAS:<p>Aducanumab (BIIB037) is an IgG1 antibody targeting amyloid beta to treat Alzheimer's; it's brain-permeable.</p>Purezza:95% - 97.10%Colore e forma:LiquidPeso molecolare:145.93 kDaSQ-3
SQ-3, a quinoline analogue, prefers α-syn (Ki=39.3nM) to Aβ (Ki=230nM), and [18F]SQ3 is a lead for α-syn probes. [1]Formula:C21H21FN2OColore e forma:SolidPeso molecolare:336.4β-Amyloid (13-27)
CAS:β-Amyloid (13-27) is a peptide consisting of amino acid of 13 to 27 of beta amyloid protein.Formula:C84H126N24O24Purezza:98%Colore e forma:SolidPeso molecolare:1856.05β-Amyloid (1-34)
CAS:This is a fragment of beta-amyloid peptide. It has amino acids 1 through 34.Formula:C170H253N47O52Purezza:98%Colore e forma:SolidPeso molecolare:3787.2β-Amyloid (29-40)
CAS:β-Amyloid (29-40) is a fragment of Amyloid-β peptide.Alzheimer's beta amyloid peptide (29-40/42) C-terminal fragments have physical and chemical propertiesFormula:C49H88N12O13SPurezza:98%Colore e forma:SolidPeso molecolare:1085.36GSK-3β inhibitor 27
GSK-3β inhibitor27 (Compound 1c) is a reversible, competitive inhibitor of GSK-3β with an IC50 value of 2.2 μM. It inhibits tau hyperphosphorylation and reduces Aβ protein aggregation, demonstrating metal chelation and neuroprotective potential. GSK-3β inhibitor27 is promising for research into neurodegenerative diseases, such as Alzheimer's disease.Formula:C16H17ClN4O2Colore e forma:SolidPeso molecolare:332.79β-Amyloid Protein Precursor 770 (135-155)
CAS:<p>Beta-Amyloid Protein Precursor 770 (135-155)Aβ Protein Precursor 770 (135-155)</p>Formula:C116H172N35O31S2Purezza:98%Colore e forma:SolidPeso molecolare:2617.96β-Amyloid (1-9)
CAS:<p>This is an N-terminal fragment of beta amyloid.</p>Formula:C42H60N14O17Purezza:98%Colore e forma:SolidPeso molecolare:1033.01AC 253
CAS:Amylin (AMY3) receptor antagonist; blocks cAMP, Ca2+, PKA, MAPK, Akt, and cFOS activity; prevents Aβ-induced neuronal death. Cyclic AC 253 variant exists.Formula:C122H196N40O39Purezza:98%Colore e forma:SolidPeso molecolare:2847.11β-Amyloid (4-10)
CAS:Antibodies corresponding to beta-amyloid (4-10) are effective in vivo inhibitors of cytotoxicity, amyloid plaque formation and special memory disturbances inFormula:C39H52N12O12Purezza:98%Colore e forma:SolidPeso molecolare:880.9Methoxy-X04
CAS:<p>Methoxy-X04, a derivative of Congo red and Chrysamine-G, is a brain-permeable fluorescent probe for amyloid-β (Aβ).</p>Formula:C23H20O3Purezza:98.96%Colore e forma:SolidPeso molecolare:344.4Chemerin-9 (149-157) TFA
Chemerin-9 (149-157) TFA is a peptide located at positions 149-157 of chemerin-9, acting as a ChemR23/CMKLR1 agonist.Formula:C56H67F3N10O15Purezza:99.77%Colore e forma:SolidPeso molecolare:1177.18RAGE antagonist peptide
CAS:<p>RAGE antagonist blocks S100P/A4, HMGB-1; hinders glioma growth, metastasis; reduces PDAC cell growth, NF-κB activity; counters TDI effects in mice.</p>Formula:C57H101N13O17SPurezza:98%Colore e forma:SolidPeso molecolare:1272.561H-Indole-3-carboxylic acid, 5-[2-hydroxy-3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]propoxy]-2-methyl-1-(4-methylphenyl)-, ethyl ester
CAS:<p>Compound 5936-0108对β-淀粉样蛋白可能具有调节作用。</p>Formula:C26H34N2O7Purezza:99.44%Colore e forma:SoildPeso molecolare:486.56β-Amyloid (1-28)
CAS:β-Amyloid (1-28) is a β-Amyloid protein fragment involved in metal binding.Formula:C145H209N41O46Purezza:98%Colore e forma:SolidPeso molecolare:3262.51β-Amyloid (1-40)
CAS:Amyloid β1-40 is one of the fragments generated after cleavage of the amyloid peptide precursor protein by β and γ secretases.Formula:C194H295N53O58SPurezza:98%Colore e forma:SolidPeso molecolare:4329.82γ-Secretase Modulators
CAS:gamma-Secretase Modulators serves as a useful treatment for Alzheimer's disease by inhibiting the production of Amyloid-β.Formula:C26H24F3N3O3Purezza:98%Colore e forma:SolidPeso molecolare:483.48p-HTAA
CAS:<p>Pentamer Hydrogen Thiophene Acetic Acid (p-HTAA) is a compound that specifically targets and labels amyloid-beta (Aβ) deposits in the brains of living mice [1].</p>Formula:C24H16O4S5Colore e forma:SolidPeso molecolare:528.71Aβ-IN-6
Aβ-IN-6 is an orally active compound exhibiting anti-inflammatory, antioxidant, and anti-oligomeric activities, with significant implications for Alzheimer'sFormula:C28H31N3O4Colore e forma:SolidPeso molecolare:473.567-Deoxy-trans-dihydronarciclasine
CAS:7-Deoxy-trans-dihydronarciclasine is an alkaloid that functions as a tobacco mosaic virus (TMV) inhibitor with an IC50 of 1.80 μM and also serves as an anti-Formula:C14H15NO6Colore e forma:SolidPeso molecolare:293.27β-Amyloid (12-20)
CAS:β-Amyloid (12-20) is a peptide fragment of β-Amyloid.Thsis peptide contain the amino acid residues VFF at position (18-20), suggesting that this triad hasFormula:C57H83N15O11Purezza:98%Colore e forma:SolidPeso molecolare:1154.36LPYFD-NH2
CAS:neuroprotective peptide that binds to amyloid beta (Aβ)Formula:C33H44N6O8Purezza:98%Colore e forma:SolidPeso molecolare:652.74β-Amyloid (1-20)
CAS:<p>This synthetic peptide consists of amino acids 1 to 20 of beta amyloid protein.</p>Formula:C113H157N31O32Purezza:98%Colore e forma:SolidPeso molecolare:2461.7
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