Beta amiloide
Gli inibitori del beta-amiloide sono composti che mirano specificamente a inibire la formazione o l'aggregazione dei peptidi beta-amiloidi, coinvolti in modo critico nella patogenesi della malattia di Alzheimer. L'accumulo di placche di beta-amiloide nel cervello è uno dei tratti patologici distintivi della malattia, contribuendo alla disfunzione neuronale e al declino cognitivo. Inibendo l'aggregazione del beta-amiloide, questi inibitori sono studiati come potenziali agenti terapeutici per rallentare o prevenire la progressione della malattia di Alzheimer. Presso CymitQuimica, offriamo una gamma di inibitori del beta-amiloide di alta qualità per supportare la tua ricerca nella neurodegenerazione, nell'aggregazione proteica e nella terapia dell'Alzheimer.
Trovati 218 prodotti di "Beta amiloide"
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RAGE antagonist peptide
CAS:<p>RAGE antagonist blocks S100P/A4, HMGB-1; hinders glioma growth, metastasis; reduces PDAC cell growth, NF-κB activity; counters TDI effects in mice.</p>Formula:C57H101N13O17SPurezza:98%Colore e forma:SolidPeso molecolare:1272.56β-Amyloid (1-11)
CAS:Anionic interaction of Beta-amyloid (1-11) with Factor XII is suspected to cause massive activation of the C4 (complement 4) system in the cerebrospinal fluidFormula:C56H76N16O22Purezza:98%Colore e forma:SolidPeso molecolare:1325.3Crenezumab
CAS:Crenezumab (MABT 5102A) is a fully humanized anti-amyloid-beta antibody that binds to multiple forms of amyloid-beta (Aβ) for the study of Alzheimer's disease.Purezza:97.5% (SDS-PAGE); 95.3% (SEC-HPLC) - 97.5% (SDS-PAGE); 95.3% (SEC-HPLC)Colore e forma:LiquidSabirnetug
CAS:Sabirnetug is a humanized IgG2κ monoclonal antibody that specifically targets the amyloid-β (A4) precursor protein.Colore e forma:LiquidSQ-3
SQ-3, a quinoline analogue, prefers α-syn (Ki=39.3nM) to Aβ (Ki=230nM), and [18F]SQ3 is a lead for α-syn probes. [1]Formula:C21H21FN2OColore e forma:SolidPeso molecolare:336.4Davunetide
CAS:<p>Davunetide: neuroprotective 8-amino acid peptide, improves daily function in schizophrenia, boosts memory in mild cognitive impairment.</p>Formula:C36H60N10O12Purezza:98%Colore e forma:SolidPeso molecolare:824.92BIBD-124
CAS:BIBD-124, with an IC50 value of 9.51 nM, effectively binds to amyloid beta (Aβ) plaques.Formula:C19H24FN3O3Colore e forma:SolidPeso molecolare:361.41β-Amyloid (1-40)
CAS:Amyloid β1-40 is one of the fragments generated after cleavage of the amyloid peptide precursor protein by β and γ secretases.Formula:C194H295N53O58SPurezza:98%Colore e forma:SolidPeso molecolare:4329.82β-Amyloid (1-34)
CAS:This is a fragment of beta-amyloid peptide. It has amino acids 1 through 34.Formula:C170H253N47O52Purezza:98%Colore e forma:SolidPeso molecolare:3787.2γ-Secretase Modulators
CAS:gamma-Secretase Modulators serves as a useful treatment for Alzheimer's disease by inhibiting the production of Amyloid-β.Formula:C26H24F3N3O3Purezza:98%Colore e forma:SolidPeso molecolare:483.48p-HTAA
CAS:<p>Pentamer Hydrogen Thiophene Acetic Acid (p-HTAA) is a compound that specifically targets and labels amyloid-beta (Aβ) deposits in the brains of living mice [1].</p>Formula:C24H16O4S5Colore e forma:SolidPeso molecolare:528.71β-Amyloid (1-20)
CAS:<p>This synthetic peptide consists of amino acids 1 to 20 of beta amyloid protein.</p>Formula:C113H157N31O32Purezza:98%Colore e forma:SolidPeso molecolare:2461.7β-Amyloid (12-20)
CAS:β-Amyloid (12-20) is a peptide fragment of β-Amyloid.Thsis peptide contain the amino acid residues VFF at position (18-20), suggesting that this triad hasFormula:C57H83N15O11Purezza:98%Colore e forma:SolidPeso molecolare:1154.36β-Amyloid (35-42)
CAS:β-Amyloid (35-42) is a peptide derived from the beta-amyloid protein, encompassing amino acids 35 through 42.Formula:C33H60N8O9SPurezza:98%Colore e forma:SolidPeso molecolare:744.94SLAFVDVLN
SLAFVDVLN is a peptide molecule that functions as a BACE-1 inhibitor, exhibiting a Ki value of 94 nM. Additionally, SLAFVDVLN is capable of reducing the production of Aβ42.Formula:C45H72N10O14Colore e forma:SolidPeso molecolare:977.11Trontinemab
CAS:Trontinemab, a bispecific humanized IgG1-κ antibody, targets the amyloid beta A4 precursor protein (APP) and transferrin receptor p90, CD71 (TFRC).Purezza:96.77% - 99%Colore e forma:Liquidβ-Amyloid (1-38), mouse, rat
CAS:β-Amyloid (1-38), derived from mice and rats, is a chemical compound comprising 38 amino acids, specifically residues 1-38 of the Aβ peptide.Colore e forma:Solidβ-Amyloid (1-9)
CAS:This is an N-terminal fragment of beta amyloid.Formula:C42H60N14O17Purezza:98%Colore e forma:SolidPeso molecolare:1033.01Begacestat
CAS:Begacestat (GSI-953) is a potent and selective gamma-secretase inhibitor that inhibits Amyloid-beta, inhibits cleavage of APP,,Alzheimer's disease.Formula:C9H8ClF6NO3S2Colore e forma:SolidPeso molecolare:391.74(Rac)-Z-Phe-Phe-FMK
CAS:(Rac)-Z-Phe-Phe-FMK (Cathepsin L-IN-2) is a cathepsin L inhibitor that inhibits the tendency of β-amyloid to induce apoptotic changes .Formula:C27H27FN2O4Purezza:98.27%Colore e forma:SolidPeso molecolare:462.51
