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COX

COX

Gli inibitori della cicloossigenasi (COX) sono composti che bloccano l'attività degli enzimi COX, coinvolti nella produzione di prostaglandine, mediatori chiave dell'infiammazione e del dolore. In neuroscienze, gli inibitori della COX sono studiati per il loro potenziale nel ridurre la neuroinfiammazione, implicata in varie malattie neurodegenerative come l'Alzheimer, il Parkinson e la sclerosi multipla. Inibendo la COX, questi composti possono aiutare a mitigare i processi infiammatori nel cervello e a proteggere dai danni neuronali. Presso CymitQuimica, offriamo una gamma di inibitori della COX per supportare la tua ricerca sulla neuroinfiammazione, la gestione del dolore e le malattie neurodegenerative.

Trovati 561 prodotti di "COX"

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  • CAFESTOL
    Targetmol
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    CAFESTOL

    CAS:
    <p>Cafestol, an ERK inhibitor, suppresses PGE2 and COX-2 by blocking NF-kB in LPS-stimulated RAW264.7 cells.</p>
    Formula:C20H28O3
    Purezza:97.06% - 99.08%
    Colore e forma:Solid
    Peso molecolare:316.43

    Ref: TM-T5727

  • NS-398
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    NS-398

    CAS:
    <p>NS-398 (N-(2-cyclohexyloxy-4-nitrophenyl)methane sulfonamide) is a COX-2 inhibitor wih anti-inflammatory activity.</p>
    Formula:C13H18N2O5S
    Purezza:99% - >99.99%
    Colore e forma:Solid
    Peso molecolare:314.36

    Ref: TM-T3214

  • TFAP
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    TFAP

    CAS:
    <p>TFAP (N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide) is a selective cyclooxygenase-1 (COX-1) inhibitor</p>
    Formula:C13H10F3N3O
    Purezza:99.87%
    Colore e forma:Solid
    Peso molecolare:281.23

    Ref: TM-T4643

  • Revaprazan hydrochloride
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    Revaprazan hydrochloride

    CAS:
    <p>Revaprazan hydrochloride (YH1885) is the hydrochloride salt form of a lipophilic, weak base with potassium-competitive acid blocking (P-CAB) activity.</p>
    Formula:C22H24ClFN4
    Purezza:99.62% - 99.91%
    Colore e forma:Solid
    Peso molecolare:398.9

    Ref: TM-T2405

  • Byakangelicol
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    Byakangelicol

    CAS:
    <p>Byakangelicol may reduce P-gp at BBB and has anti-inflammatory effects by hindering COX-2 and PGE2 in A549 cells.</p>
    Formula:C17H16O6
    Purezza:98.78% - 99.55%
    Colore e forma:Solid
    Peso molecolare:316.31

    Ref: TM-T6S0077

  • Compound Lup-20(29)-en-3-yl acetate
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    Compound Lup-20(29)-en-3-yl acetate

    <p>Lupeol acetate, a derivative of Lupeol, inhibits the progression of rheumatoid arthritis by downregulating TNF-α, IL-1β, MCP-1, COX-2, VEGF and granzyme B.</p>
    Formula:C32H52O2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:468.75

    Ref: TM-TC0036

  • N-tert-butyl-α-Phenylnitrone
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    N-tert-butyl-α-Phenylnitrone

    CAS:
    <p>N-tert-butyl-α-Phenylnitrone ((Z)-N-benzylidene-2-Methylpropan-2-aMine oxide) inhibits COX2 catalytic activity.</p>
    Formula:C11H15NO
    Purezza:99.46% - 99.84%
    Colore e forma:Solid
    Peso molecolare:177.24

    Ref: TM-T23046

  • CAY10404
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    CAY10404

    CAS:
    <p>CAY10404: potent COX-1/2 inhibitor; blocks PKB/Akt, MAPK pathways; triggers NSC-LC apoptosis; analgesic, anti-inflammatory, anti-cancer.</p>
    Formula:C17H12F3NO3S
    Purezza:99.02%
    Colore e forma:Solid
    Peso molecolare:367.34

    Ref: TM-T8656

  • Tinoridine hydrochloride
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    Tinoridine hydrochloride

    CAS:
    <p>Tinoridine HCl is an NSAID that inhibits lipid peroxides and renin release, unlike indomethacin and corticosteroids.</p>
    Formula:C17H21ClN2O2S
    Purezza:97.49%
    Colore e forma:Solid
    Peso molecolare:352.88

    Ref: TM-T4313

  • Isofraxidin
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    Isofraxidin

    CAS:
    <p>Isofraxidin combats leukemia, ALI, and inflammation by modulating ROS, COX-2, PGE2, TNF-α, and p38/ERK1/2 pathways.</p>
    Formula:C11H10O5
    Purezza:99.51% - ≥95%
    Colore e forma:Solid
    Peso molecolare:222.19

    Ref: TM-T5S0045

  • Tolmetin
    Targetmol
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    Tolmetin

    CAS:
    <p>Tolmetin (Tolectin) NSAID; acts as a cyclooxygenase inhibitor; classified as an anti-inflammatory.</p>
    Formula:C15H15NO3
    Purezza:99.74% - >99.99%
    Colore e forma:Off-White Crystalline Power
    Peso molecolare:257.28

    Ref: TM-T2550

  • [10]-Shogaol
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    [10]-Shogaol

    CAS:
    <p>[10]-Shogaol (10-Shogaol) is an extract from ginger displaying antioxidant activity. It also may contain hypolipidemic and insulin-sensitizing effects.</p>
    Formula:C21H32O3
    Purezza:97.64% - 98.65%
    Colore e forma:Solid
    Peso molecolare:332.48

    Ref: TM-T5431

  • α-Spinasterol
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    α-Spinasterol

    CAS:
    <p>α-Spinasterol is a transient receptor potential vanilloid 1 (TRPV1) antagonist, has anti-inflammatory, antidepressant, antioxidant and antinociceptive effects.</p>
    Formula:C29H48O
    Purezza:97.03% - 99.58%
    Colore e forma:Solid
    Peso molecolare:412.69

    Ref: TM-TN1377

  • Mofezolac
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    Mofezolac

    CAS:
    <p>Mofezolac (formerly known as Disopain or N-22) is a highly selective COX-1 (cyclooxygenase-1) inhibitor with COXs selectivity index &gt; 6000</p>
    Formula:C19H17NO5
    Purezza:99.29%
    Colore e forma:Solid
    Peso molecolare:339.34

    Ref: TM-T5460

  • Firocoxib
    Targetmol
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    Firocoxib

    CAS:
    <p>Firocoxib (ML 1785713) is a selective non-steroidal inhibitor of cycooxygenase-2 (COX-2) (IC50 of 0.13 μM), with anti-inflammatory for use in dogs and horses.</p>
    Formula:C17H20O5S
    Purezza:99.84%
    Colore e forma:Solid
    Peso molecolare:336.4

    Ref: TM-T7596

  • Parecoxib
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    Parecoxib

    CAS:
    <p>Parecoxib (SC 69124) is an effective and selective COX-2 inhibitor.</p>
    Formula:C19H18N2O4S
    Purezza:99.71% - 99.78%
    Colore e forma:Solid
    Peso molecolare:370.42

    Ref: TM-T1780

  • Tazofelone
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    Tazofelone

    CAS:
    <p>Tazofelone (LY-213829) is a NSAID used for the treatment of inflammatory bowel disease.</p>
    Formula:C18H27NO2S
    Purezza:99.89%
    Colore e forma:Solid
    Peso molecolare:321.48

    Ref: TM-T22437

  • (E)-Ethyl p-methoxycinnamate
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    (E)-Ethyl p-methoxycinnamate

    CAS:
    <p>1. (E)-Ethyl p-methoxycinnamate (EPMC) is an anticarcinogenic agent. 2. (E)-Ethyl p-methoxycinnamate (EPMC) is a glutathion S tranferase inhibitor.</p>
    Formula:C12H14O3
    Purezza:97.43%
    Colore e forma:Solid
    Peso molecolare:206.24

    Ref: TM-T2S1625

  • RK33
    Targetmol
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    RK33

    CAS:
    <p>"RK33 is a DDX3 inhibitor causing G1 arrest, apoptosis, and radiation sensitization in DDX3-overexpressing cells."</p>
    Formula:C23H20N6O3
    Purezza:99.04% - 99.72%
    Colore e forma:Solid
    Peso molecolare:428.44

    Ref: TM-T6970

  • Cis-5-Dodecenoic Acid
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    Cis-5-Dodecenoic Acid

    CAS:
    <p>Cis-5-Dodecenoic Acid is a monounsaturated fatty acid that has a C12 chain as a backbone and a cis double bond at the C5 position.</p>
    Formula:C12H22O2
    Purezza:98% - 99.37%
    Colore e forma:Solid
    Peso molecolare:198.3

    Ref: TM-T8240

  • Madecassic acid
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    Madecassic acid

    CAS:
    <p>Madecassic acid (L-fucopyranose) is extracted from the whole herb of Centella asiatica.</p>
    Formula:C30H48O6
    Purezza:98.80% - 99.69%
    Colore e forma:Solid
    Peso molecolare:504.7

    Ref: TM-T2758

  • Gnetol
    Targetmol
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    Gnetol

    CAS:
    <p>Gnetol inhibits butyrylcholinesterase (IC50: 1.3 μM), tyrosinase, melanin synthesis in B16 cells, and AA-induced platelet aggregation.</p>
    Formula:C14H12O4
    Purezza:98.55% - ≥95%
    Colore e forma:Solid
    Peso molecolare:244.24

    Ref: TM-T7052

  • Columbin
    Targetmol
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    Columbin

    CAS:
    <p>Columbin: anti-inflammatory, prevents colon cancer, inhibits PLA2 in RBC dose-dependently.</p>
    Formula:C20H22O6
    Purezza:99.34% - 99.74%
    Colore e forma:Solid
    Peso molecolare:358.39

    Ref: TM-T4S0590

  • S-(+)-Marmesin
    Targetmol
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    S-(+)-Marmesin

    CAS:
    <p>S-(+)-Marmesin (marmesin) is a coumarin originally isolated from the mature bark of A. marmelos,exhibiting COX-2/5-LOX dual inhibitory activity.</p>
    Formula:C14H14O4
    Purezza:98.00% - ≥98%
    Colore e forma:Solid
    Peso molecolare:246.26

    Ref: TM-T5759

  • Losartan Carboxaldehyde
    Targetmol
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    Losartan Carboxaldehyde

    CAS:
    <p>Losartan Carboxaldehyde is an endothelial cyclooxygenase (COX)-2 inhibitor.</p>
    Formula:C22H21ClN6O
    Purezza:99.1%
    Colore e forma:Solid
    Peso molecolare:420.89

    Ref: TM-T7838

  • Esculentoside A
    Targetmol
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    Esculentoside A

    CAS:
    <p>Esculentoside A dampens inflammation in ALI, modulates T cells, and could treat autoimmune diseases and BXSB mice by adjusting cytokines and renal cells.</p>
    Formula:C42H66O16
    Purezza:98% - 99.85%
    Colore e forma:Solid
    Peso molecolare:826.96

    Ref: TM-T3877

  • Isoorientin
    Targetmol
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    Isoorientin

    CAS:
    <p>Isoorientin (Homoorientin) has antioxidant activity.</p>
    Formula:C21H20O11
    Purezza:98.84% - 99.93%
    Colore e forma:Solid
    Peso molecolare:448.38

    Ref: TM-T6S0722

  • Psoralidin
    Targetmol
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    Psoralidin

    CAS:
    <p>Psoralidin inhibits Akt phosphorylation and phosphatidylinositol 3-kinase activation and transcriptionally.</p>
    Formula:C20H16O5
    Purezza:98% - 99.61%
    Colore e forma:Solid
    Peso molecolare:336.34

    Ref: TM-T3399

  • 2,5-Di-tert-butylhydroquinone
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    2,5-Di-tert-butylhydroquinone

    CAS:
    <p>2,5-Di-tert-butylhydroquinone (BHQ) is an effective and selective endoplasmic reticulum Ca2+-ATPase inhibitor.</p>
    Formula:C14H22O2
    Purezza:97.11%
    Colore e forma:Pelletslargecrystals
    Peso molecolare:222.32

    Ref: TM-T7540

  • (+)-Catechin Hydrate
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    (+)-Catechin Hydrate

    CAS:
    <p>(+)-Catechin Hydrate is an antioxidant flavonoid of plant origin; a free radical scavenger, preventing free radical-mediated damage in a variety of biological</p>
    Formula:C15H16O7
    Purezza:99.03% - 99.96%
    Colore e forma:Solid
    Peso molecolare:308.28

    Ref: TM-T2778

  • Chlorotrianisene
    Targetmol
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    Chlorotrianisene

    CAS:
    <p>Chlorotrianisene, a synthetic SERM, is orally active, lipophilic, and has estrogenic and antiestrogenic effects.</p>
    Formula:C23H21ClO3
    Purezza:98.88% - 99.03%
    Colore e forma:Crystals From Methanol Physical Description Small White Crystals Or White Powder Softens At 226°F Odorless (Ntp 1992)
    Peso molecolare:380.86

    Ref: TM-T2569

  • Avicularin
    Targetmol
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    Avicularin

    CAS:
    <p>Avicularin reduces inflammation via ERK pathway in RAW 264.7 cells and hinders lipid buildup in adipocytes by limiting glucose uptake and fatty acid synthesis.</p>
    Formula:C20H18O11
    Purezza:97.02% - 99.94%
    Colore e forma:White Powder
    Peso molecolare:434.35

    Ref: TM-T6S0117

  • [8]-Shogaol
    Targetmol
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    [8]-Shogaol

    CAS:
    <p>[8]-Shogaol is a component of ginger and maintains anti-inflammatory activity as a cyclooxygenase-2 inhibitor.</p>
    Formula:C19H28O3
    Purezza:97.01%
    Colore e forma:Solid
    Peso molecolare:304.42

    Ref: TM-T5430

  • Diclofenac Potassium
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    Diclofenac Potassium

    CAS:
    <p>Diclofenac Potassium (CGP-45840B) is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.</p>
    Formula:C14H10Cl2KNO2
    Purezza:99.51%
    Colore e forma:White To Yellowish Crystalline Powder
    Peso molecolare:334.24

    Ref: TM-T6470

  • Lumiracoxib
    Targetmol
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    Lumiracoxib

    CAS:
    <p>Lumiracoxib (Prexige) is a novel, selective COX-2 inhibitor with IC50 and Ki of 0.14 μM and 0.06 μM, exhibits 515-fold selectivity over COX-1. Phase 4.</p>
    Formula:C15H13ClFNO2
    Purezza:96.64% - 99.77%
    Colore e forma:Pale Yellow Solid
    Peso molecolare:293.72

    Ref: TM-T6574

  • (-)-Catechin gallate
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    (-)-Catechin gallate

    CAS:
    <p>(-)-Catechin gallate inhibits 6PGD, IDH, Beta-secretase, and fights chloroquine-sensitive/resistant Plasmodium falciparum.</p>
    Formula:C22H18O10
    Purezza:97.74% - >99.99%
    Colore e forma:Solid
    Peso molecolare:442.37

    Ref: TM-T3682

  • Adelmidrol
    Targetmol
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    Adelmidrol

    CAS:
    <p>Adelmidrol is an anti-inflammatory ethanolamide derivative of azelaic acid.</p>
    Formula:C13H26N2O4
    Purezza:99.35% - 99.73%
    Colore e forma:Solid
    Peso molecolare:274.36

    Ref: TM-T3954

  • 7,3',4'-Tri-O-methylluteolin
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    7,3',4'-Tri-O-methylluteolin

    CAS:
    <p>7,3',4'-Tri-O-methylluteolin is anti-inflammatory, antibacterial, antifungal, and has moderate antitrypanosomal effects (MIC 19.0 ug/ml).</p>
    Formula:C18H16O6
    Purezza:98.66% - 99.79%
    Colore e forma:Solid
    Peso molecolare:328.32

    Ref: TM-TN1291

  • sphondin
    Targetmol
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    sphondin

    CAS:
    <p>Sphondin inhibits IL-1beta, reduces COX-2 and PGE(2) in A549 cells, and has anticonvulsant, anti-inflammatory, anti-proliferative properties.</p>
    Formula:C12H8O4
    Purezza:99.9% - ≥95%
    Colore e forma:Solid
    Peso molecolare:216.19

    Ref: TM-T5758

  • Ginsenoside Rb3
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    Ginsenoside Rb3

    CAS:
    <p>Ginsenoside Rb3 (Gypenoside IV) is a natural triterpenoid saponin, exhibiting inhibition effect on TNFα-induced NF-κB transcriptional activity.</p>
    Formula:C53H90O22
    Purezza:98% - 99.98%
    Colore e forma:Solid
    Peso molecolare:1079.27

    Ref: TM-T3918

  • SC-58125
    Targetmol
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    SC-58125

    CAS:
    <p>SC-58125 is a selective cyclooxygenase 2 (COX-2) inhibitor. SC-58125 exhibits antitumor activity, and also inhibits oedema at sites of inflammation.</p>
    Formula:C17H12F4N2O2S
    Purezza:99.57%
    Colore e forma:Solid
    Peso molecolare:384.35

    Ref: TM-T23333

  • Roburic acid
    Targetmol
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    Roburic acid

    CAS:
    <p>Roburic acid and phenethyl-trans-ferulate inhibit COX-1 and COX-2.</p>
    Formula:C30H48O2
    Purezza:98.765% - 99.88%
    Colore e forma:Solid
    Peso molecolare:440.7

    Ref: TM-T3883

  • Tinoridine
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    Tinoridine

    CAS:
    <p>Tinoridine is a quinoline derivative analog that acts by inhibiting the production of cyclooxygenase-2 (COX-2).</p>
    Formula:C17H20N2O2S
    Purezza:99.08%
    Colore e forma:Solid
    Peso molecolare:316.42

    Ref: TM-T50001

  • FK 3311
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    FK 3311

    CAS:
    <p>FK 3311 (COX-2 Inhibitor V) is a cell permeable and orally available sulfonanilide that acts as a COX-2 inhibitor and non-steroidal anti-inflammatory drug (</p>
    Formula:C15H13F2NO4S
    Purezza:97.98%
    Colore e forma:Solid
    Peso molecolare:341.33

    Ref: TM-T7207

  • Propyphenazone
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    Propyphenazone

    CAS:
    <p>Propyphenazone: an anti-inflammatory, analgesic, antipyretic pyrazolone; prodrug; COX-2 inhibitor.</p>
    Formula:C14H18N2O
    Purezza:99.64%
    Colore e forma:Solid
    Peso molecolare:230.31

    Ref: TM-T5010

  • Teriflunomide impurity 3
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    Teriflunomide impurity 3

    CAS:
    <p>Teriflunomide impurity 3 (4-Amino-N-(4-trifluoromethylphenyl)benzamide) is a selective COX-1 inhibitor(IC50 of 30 μM).</p>
    Formula:C14H11F3N2O
    Purezza:99.62%
    Colore e forma:Solid
    Peso molecolare:280.25

    Ref: TM-T9042

  • Otenaproxesul
    Targetmol
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    Otenaproxesul

    CAS:
    <p>Otenaproxesul (ATB 346) is a novel hydrogen sulphide-releasing derivative of naproxen with markedly reduced toxicity.</p>
    Formula:C21H19NO3S
    Purezza:98.76% - 99.13%
    Colore e forma:Solid
    Peso molecolare:365.45

    Ref: TM-T1867

  • (-)-Epicatechin
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    (-)-Epicatechin

    CAS:
    <p>(-)-Epicatechin (Epicatechin) is an inhibitor of cyclooxygenase-1 (COX-1), inhibiting the IL-1β-induced expression of iNOS by blocking the nuclear localization</p>
    Formula:C15H14O6
    Purezza:98.55% - 98.80%
    Colore e forma:Solid
    Peso molecolare:290.27

    Ref: TM-T2856

  • Fenoprofen Calcium
    Targetmol
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    Fenoprofen Calcium

    CAS:
    <p>Fenoprofen Calcium is a nonsteroidal, anti-inflammatory antiarthritic agent.</p>
    Formula:C30H26CaO6
    Purezza:99.24% - 99.66%
    Colore e forma:Solid
    Peso molecolare:522.6

    Ref: TM-T6497

  • SC-236
    Targetmol
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    SC-236

    CAS:
    <p>SC-236 (Sc 236) is an orally active and selective inhibitor of COX-2 (IC50 of 0.005 μM and 17.8 μM for COX-2 and COX-1, respectively).</p>
    Formula:C16H11ClF3N3O2S
    Purezza:99.74%
    Colore e forma:Solid
    Peso molecolare:401.79

    Ref: TM-T8505