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COX

COX

Gli inibitori della cicloossigenasi (COX) sono composti che bloccano l'attività degli enzimi COX, coinvolti nella produzione di prostaglandine, mediatori chiave dell'infiammazione e del dolore. In neuroscienze, gli inibitori della COX sono studiati per il loro potenziale nel ridurre la neuroinfiammazione, implicata in varie malattie neurodegenerative come l'Alzheimer, il Parkinson e la sclerosi multipla. Inibendo la COX, questi composti possono aiutare a mitigare i processi infiammatori nel cervello e a proteggere dai danni neuronali. Presso CymitQuimica, offriamo una gamma di inibitori della COX per supportare la tua ricerca sulla neuroinfiammazione, la gestione del dolore e le malattie neurodegenerative.

Trovati 561 prodotti di "COX"

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  • Ketorolac-d5
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    Ketorolac-d5

    CAS:
    <p>Ketorolac-d5 is a deuterated compound of ketorolac for isotope tracing. Ketorolac is a non-steroidal anti-inflammatory agent and inhibitor of COX-1 and COX-2.</p>
    Formula:C15H8D5NO3
    Purezza:98.99%
    Colore e forma:Solid
    Peso molecolare:260.3

    Ref: TM-T11754

  • AHR-10037
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    AHR-10037

    CAS:
    <p>AHR-10037, a NSAID, offers pain relief, fever reduction, safety, and low stomach risk, acting as a prodrug for COX inhibitors.</p>
    Formula:C15H13ClN2O2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:288.73

    Ref: TM-T23676

  • Amfenac
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    Amfenac

    CAS:
    <p>Amfenac promotes apoptosis in ARPE-19 cell culture.</p>
    Formula:C15H13NO3
    Colore e forma:Solid
    Peso molecolare:255.27

    Ref: TM-T1720L

  • Pelubiprofen
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    Pelubiprofen

    CAS:
    <p>Pelubiprofen is a non-steroidal anti-inflammatory agent and a COX-2 inhibitor, which effectively reduces PGE(2) production by inhibiting COX activity.</p>
    Formula:C16H18O3
    Purezza:99.69%
    Colore e forma:Solid
    Peso molecolare:258.31

    Ref: TM-T16464

  • Tilmacoxib
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    Tilmacoxib

    CAS:
    <p>Tilmacoxib is a highly selective, time-dependent, and irreversible inhibitor of human COX-2 ( IC50: 85 nM in an enzyme assay).</p>
    Formula:C16H19FN2O3S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:338.4

    Ref: TM-T15630

  • COX-2/5-LOX-IN-3
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    COX-2/5-LOX-IN-3

    CAS:
    <p>COX-2/5-LOX-IN-3 inhibits COX-2/5-LOX with IC50s: COX-1 45.73μM, COX-2 5.45μM, 5-LOX 4.33μM; promising for inflammation research.</p>
    Formula:C17H16ClN3O2S
    Colore e forma:Solid
    Peso molecolare:361.85

    Ref: TM-T61352

  • Pifoxime
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    Pifoxime

    CAS:
    <p>Pifoxime: a NSAID with COX-1/2 inhibition, used in anti-inflammatory treatment and neuropsychiatric studies.</p>
    Formula:C15H20N2O3
    Colore e forma:Solid
    Peso molecolare:276.33

    Ref: TM-T69473

  • COX/5-LOX-IN-1
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    COX/5-LOX-IN-1

    CAS:
    <p>Compound 6b is a potent dual inhibitor of COX/5-LOX with IC50s: 1.07μM (COX-1), 0.55μM (COX-2), 0.28μM (5-LOX) for inflammation research.</p>
    Formula:C18H30O3
    Colore e forma:Solid
    Peso molecolare:294.43

    Ref: TM-T60630

  • Loxoprofenol-SRS tromethamine
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    Loxoprofenol-SRS tromethamine

    CAS:
    <p>Loxoprofenol-SRS tromethamine (HR1405-01), a metabolite of Loxoprofen, is a safe IV NSAID with strong anti-inflammatory and pain relief properties.</p>
    Formula:C19H31NO6
    Colore e forma:Solid
    Peso molecolare:369.45

    Ref: TM-T72146

  • COX-2-IN-26
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    COX-2-IN-26

    CAS:
    <p>COX-2-IN-26: Oral, selective COX-2 inhibitor, low IC50s; anti-inflammatory with GI safety.</p>
    Formula:C23H21N7OS3
    Colore e forma:Solid
    Peso molecolare:507.65

    Ref: TM-T63480

  • COX-2-IN-2
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    COX-2-IN-2

    CAS:
    <p>COX-2-IN-2 selectively inhibits COX2 (IC50: 0.24 μM); COX-2-IN-1 offers anti-inflammatory and pain relief.</p>
    Formula:C17H12FN3O2S
    Purezza:97.62%
    Colore e forma:Solid
    Peso molecolare:341.36

    Ref: TM-T10032

  • K-80001
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    K-80001

    CAS:
    <p>K-80001 is a selective RXRα ligand and a COX-1/2 inhibitor, exhibiting IC50 values of 82.9μM for RXRα, 3.4μM for COX-1, and 1.2μM for COX-2, respectively [1].</p>
    Formula:C20H17FO2
    Colore e forma:Solid
    Peso molecolare:308.35

    Ref: TM-T79181

  • COX-2-IN-17
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    COX-2-IN-17

    CAS:
    <p>COX-2-IN-17 is a potent, blood-brain barrier permeable COX-2 (cyclooxygenase-2) inhibitor (IC50: 0.02 μM) with anti-inflammatory and analgesic activity.</p>
    Formula:C20H23ClN6O2
    Colore e forma:Solid
    Peso molecolare:414.89

    Ref: TM-T62142

  • FR-188582
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    FR-188582

    CAS:
    <p>FR-188582 is a highly selective cyclooxygenase (COX)-2 inhibitor (IC50: 17 nM).</p>
    Formula:C16H13ClN2O2S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:332.8

    Ref: TM-T15345

  • MK-0703
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    MK-0703

    CAS:
    <p>MK-0703 is a selective cyclooxygenase-2 inhibitor.</p>
    Formula:C17H22O5S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:338.42

    Ref: TM-T28052

  • COX-2/5-LOX-IN-1
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    COX-2/5-LOX-IN-1

    CAS:
    <p>COX-2/5-LOX-IN-1, a benzothiophen-2-yl pyrazole, inhibits COX-2 &amp; 5-LOX with IC50: COX-1 (12.13μM), COX-2 (0.4μM), 5-LOX (4.96μM). Better than Celecoxib.</p>
    Formula:C14H10ClN3O4S2
    Colore e forma:Solid
    Peso molecolare:383.83

    Ref: TM-T61674

  • Heterophdoid A
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    Heterophdoid A

    CAS:
    <p>Heterophdoid A is an anti-inflammatory agent that inhibits NO production in BV-2 cells (IC50: 5.93 μM).</p>
    Formula:C26H42O10
    Colore e forma:Solid
    Peso molecolare:514.61

    Ref: TM-T63570

  • Nitroflurbiprofen
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    Nitroflurbiprofen

    CAS:
    <p>Nitroflurbiprofen (Nitroxybutyl flurbiprofen) is a NO-releasing COX inhibitor and modulates the increased intrahepatic vascular tone in portal hypertensive</p>
    Formula:C19H20FNO5
    Purezza:99.88%
    Colore e forma:Solid
    Peso molecolare:361.36

    Ref: TM-T16329

  • Timegadine
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    Timegadine

    CAS:
    <p>Timegadine is a competitive inhibitor of COX and lipo-oxygenase, with IC50s ranging from 5 nM (washed rabbit platelets) to 20 μM (rat brain) for COX and 100 μM</p>
    Formula:C20H23N5S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:365.5

    Ref: TM-T13160

  • COX-2-IN-18
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    COX-2-IN-18

    CAS:
    <p>COX-2-IN-18 is a potent COX-2 inhibitor similar to Celecoxib, showing promise in cancer research. IC50=0.775μM.</p>
    Formula:C18H19N3O3S2
    Colore e forma:Solid
    Peso molecolare:389.49

    Ref: TM-T61760