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COX

COX

Gli inibitori della cicloossigenasi (COX) sono composti che bloccano l'attività degli enzimi COX, coinvolti nella produzione di prostaglandine, mediatori chiave dell'infiammazione e del dolore. In neuroscienze, gli inibitori della COX sono studiati per il loro potenziale nel ridurre la neuroinfiammazione, implicata in varie malattie neurodegenerative come l'Alzheimer, il Parkinson e la sclerosi multipla. Inibendo la COX, questi composti possono aiutare a mitigare i processi infiammatori nel cervello e a proteggere dai danni neuronali. Presso CymitQuimica, offriamo una gamma di inibitori della COX per supportare la tua ricerca sulla neuroinfiammazione, la gestione del dolore e le malattie neurodegenerative.

Trovati 561 prodotti di "COX"

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  • COX-2/sEH-IN-1
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    COX-2/sEH-IN-1

    CAS:
    <p>COX-2/sEH-IN-1, oral dual inhibitor: COX-2 (IC50=1.24 μM), sEH (IC50=0.40 μM); boosts anti-inflammatory action, cuts heart risk.</p>
    Formula:C23H18F3N5O3S
    Colore e forma:Solid
    Peso molecolare:501.48

    Ref: TM-T63398

  • K-80001
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    K-80001

    CAS:
    <p>K-80001 is a selective RXRα ligand and a COX-1/2 inhibitor, exhibiting IC50 values of 82.9μM for RXRα, 3.4μM for COX-1, and 1.2μM for COX-2, respectively [1].</p>
    Formula:C20H17FO2
    Colore e forma:Solid
    Peso molecolare:308.35

    Ref: TM-T79181

  • Anti-inflammatory agent 8
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    Anti-inflammatory agent 8

    CAS:
    <p>Anti-inflammatory agent 8 targets COX-2 over COX-1, IC50 of 0.09 nM, orally bioavailable.</p>
    Formula:C18H15N5OS2
    Colore e forma:Solid
    Peso molecolare:381.47

    Ref: TM-T61637

  • Apricoxib
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    Apricoxib

    CAS:
    <p>Apricoxib: oral NSAID with antiangiogenic, antineoplastic properties; inhibits COX-2, may reduce tumor growth and angiogenesis.</p>
    Formula:C19H20N2O3S
    Colore e forma:Solid
    Peso molecolare:356.44

    Ref: TM-T70018

  • Naproxen glucuronide
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    Naproxen glucuronide

    CAS:
    <p>Naproxen glucuronide: NSAID, propionic class, eases pain, fever, inflammation. Nonselective COX blocker.</p>
    Formula:C20H22O9
    Colore e forma:Solid
    Peso molecolare:406.38

    Ref: TM-T69267

  • COX-2-IN-18
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    COX-2-IN-18

    CAS:
    <p>COX-2-IN-18 is a potent COX-2 inhibitor similar to Celecoxib, showing promise in cancer research. IC50=0.775μM.</p>
    Formula:C18H19N3O3S2
    Colore e forma:Solid
    Peso molecolare:389.49

    Ref: TM-T61760

  • PD 127443
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    PD 127443

    CAS:
    <p>PD 127443 is a Leukotriene B4 antagonist, it is also a dual inhibitor of cyclooxygenase and 5-lipoxygenase.</p>
    Formula:C20H28N2O
    Colore e forma:Solid
    Peso molecolare:312.45

    Ref: TM-T28325

  • COX-2-IN-32
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    COX-2-IN-32

    CAS:
    <p>COX-2-IN-32 (Compound 2f) is a dual inhibitor of iNOS and COX-2, known to downregulate NF-κB expression.</p>
    Formula:C25H24O6
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:420.45

    Ref: TM-T79130

  • ASP-6537
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    ASP-6537

    CAS:
    <p>ASP-6537 is a selective and reversible inhibitor of cyclooxygenase-1.</p>
    Formula:C17H17N3O3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:311.34

    Ref: TM-T23758

  • Pifoxime
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    Pifoxime

    CAS:
    <p>Pifoxime: a NSAID with COX-1/2 inhibition, used in anti-inflammatory treatment and neuropsychiatric studies.</p>
    Formula:C15H20N2O3
    Colore e forma:Solid
    Peso molecolare:276.33

    Ref: TM-T69473

  • COX-2/5-LOX-IN-3
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    COX-2/5-LOX-IN-3

    CAS:
    <p>COX-2/5-LOX-IN-3 inhibits COX-2/5-LOX with IC50s: COX-1 45.73μM, COX-2 5.45μM, 5-LOX 4.33μM; promising for inflammation research.</p>
    Formula:C17H16ClN3O2S
    Colore e forma:Solid
    Peso molecolare:361.85

    Ref: TM-T61352

  • COX-2-IN-16
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    COX-2-IN-16

    CAS:
    <p>COX-2-IN-16: potent, selective oral COX-2 blocker, IC50=102 μM, reduces NO, anti-inflammatory.</p>
    Formula:C19H12BrN3O2
    Colore e forma:Solid
    Peso molecolare:394.22

    Ref: TM-T61821

  • ATB-337
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    ATB-337

    CAS:
    <p>S-Diclofenac, an NSAID with H2S-releasing moiety, protects gastric mucosa while inhibiting prostaglandins.</p>
    Formula:C23H15Cl2NO2S3
    Colore e forma:Solid
    Peso molecolare:504.47

    Ref: TM-T21939

  • COX-2-IN-20
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    COX-2-IN-20

    CAS:
    <p>COX-2-IN-20 (Compound 5d) is a selective and orally active inhibitor of COX-2 (IC 50 = 17.9 nM) with anti-inflammatory activity [1].</p>
    Formula:C11H9ClFN3O2
    Colore e forma:Solid
    Peso molecolare:269.66

    Ref: TM-T60464

  • Prostaglandin G/H synthase 1 inhibitor
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    Prostaglandin G/H synthase 1 inhibitor

    CAS:
    <p>Prostaglandin G/H synthase 1 inhibitor (CP 74006) is a selective D5D inhibitor with an IC(50) value of 20 nM.</p>
    Formula:C13H11ClN2O
    Purezza:99.76%
    Colore e forma:Solid
    Peso molecolare:246.69

    Ref: TM-T27066

  • Flosulide
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    Flosulide

    CAS:
    <p>Flosulide is an effective selective COX-2 inhibitor for the treatment of inflammatory diseases.</p>
    Formula:C16H13F2NO4S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:353.34

    Ref: TM-T11296

  • AHR-6293
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    AHR-6293

    CAS:
    <p>AHR-6293 is used to distinguishing the effect of anti-platelet aggregating drug properties and the effect of anti-inflammatory properties.</p>
    Formula:C15H12ClNO3
    Colore e forma:Solid
    Peso molecolare:289.71

    Ref: TM-T23684

  • NCX 466
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    NCX 466

    CAS:
    <p>cyclooxygenase (COX)-inhibiting nitric oxide (NO) donor</p>
    Formula:C20H24N2O9
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:436.41

    Ref: TM-T23062

  • Etoricoxib HCl
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    Etoricoxib HCl

    CAS:
    <p>Etoricoxib HCl is a synthetic NSAID that inhibits COX-2, blocking prostaglandin production.</p>
    Formula:C18H16Cl2N2O2S
    Colore e forma:Solid
    Peso molecolare:395.30

    Ref: TM-T1574L

  • Lobeglitazone Sulfate
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    Lobeglitazone Sulfate

    CAS:
    <p>Lobeglitazone Sulfate (CKD-501) is an anti-inflammatory thiazolidinedione that prevents NLRP3 inflammasome activation and is used in T2DM research.</p>
    Formula:C24H26N4O9S2
    Purezza:98.69%
    Colore e forma:Solid
    Peso molecolare:578.61

    Ref: TM-T27841