GluR
Gli inibitori dei recettori del glutammato sono composti che bloccano l'attività dei recettori del glutammato, i principali recettori dei neurotrasmettitori eccitatori nel cervello. Questi recettori svolgono un ruolo cruciale nella trasmissione sinaptica, nella plasticità, nell'apprendimento e nella memoria. La disregolazione della segnalazione del glutammato è associata a vari disturbi neurologici, come l'epilessia, l'ictus e le malattie neurodegenerative. Gli inibitori dei recettori del glutammato sono essenziali per studiare i meccanismi dell'eccitotossicità e sviluppare strategie neuroprotettive. Presso CymitQuimica, offriamo una gamma di inibitori dei recettori del glutammato per supportare la vostra ricerca sulla funzione sinaptica, la neuroprotezione e i disturbi cognitivi.
Trovati 263 prodotti per "GluR".
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Basimglurant
CAS:Basimglurant (CTEP Derivative) is a potent, selective and orally available modulator of mGlu5 negative allosteric(Kd of 1.1 nM).Formula:C18H13ClFN3Purezza:98.35%Colore e forma:SolidPeso molecolare:325.77Ref: TM-T12717
1mg71,00€5mg152,00€1mL*10mM (DMSO)167,00€10mg222,00€25mg358,00€50mg532,00€100mg665,00€200mg898,00€LY339434 HCl
LY339434 HCl is a low affinity GluR5 erythrocyte receptor agonist.LY339434 HCl causes rapid neuronal death primarily by affecting N-methyl-D-aspartate (NMDA)Formula:C18H20ClNO4Purezza:97.10% - 97.19%Colore e forma:SoildPeso molecolare:349.81VU0650786
CAS:VU0650786: selective mGlu3 NAM, CNS-penetrant, IC50 392 nM, shows antidepressant/anxiolytic effects in rodents.Formula:C18H15ClFN5O2Purezza:99.09%Colore e forma:SolidPeso molecolare:387.8Ref: TM-T13318
1mg90,00€5mg222,00€1mL*10mM (DMSO)245,00€10mg313,00€25mg530,00€50mg757,00€100mg1.044,00€DHPG
CAS:DHPG is a potent Group I mGluR agonist; doesn't affect Group II/III; linked to phospholipase D.Formula:C8H9NO4Purezza:99.55%Colore e forma:SolidPeso molecolare:183.16Org-26576
CAS:Org-26576 is a positive allosteric modulator of the AMPA receptor.Formula:C11H12N2O2Purezza:99.67%Colore e forma:White SolidPeso molecolare:204.23Piracetam
CAS:Piracetam (UCB-6215), a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), is used in therapy of the extensive cognitive disorders.Formula:C6H10N2O2Purezza:97.16%Colore e forma:SolidPeso molecolare:142.16Decoglurant
CAS:Decoglurant (RO4995819) is a negative allosteric modulator of mGluR2 and mGluR3 and it also is developed as an antidepressant.Formula:C21H11F6N5Purezza:99.77%Colore e forma:SolidPeso molecolare:447.34Ref: TM-T15090
1mg52,00€5mg111,00€1mL*10mM (DMSO)152,00€10mg164,00€25mg294,00€50mg411,00€100mg572,00€200mg772,00€γ-DGG acetate(6729-55-1 free base)
CAS:gamma-DGG acetate(6729-55-1 free base) (γ-D-Glutamylglycine) is a competitive blocker of AMPA receptor.Formula:C9H16N2O7Purezza:99.92%Colore e forma:SolidPeso molecolare:264.23(R)-3,4-DCPG HCl
(R)-3,4-DCPG HCl is a potent and selective mGlu8a receptor agonist that activates metabotropic glutamate receptors on primary afferent terminals in the neonatalFormula:C10H10ClNO6Purezza:99.74% - 99.83%Colore e forma:SolidPeso molecolare:275.64KM02894
CAS:KM02894 inhibits glutamate release, potentially reducing cancer-induced bone pain in tumor studies.Formula:C7H9N3OS2Purezza:99.98%Colore e forma:SolidPeso molecolare:215.3AZD-8529 mesylate
CAS:AZD-8529 mesylate is a highly selective, and orally bioavailable positive allosteric modulator of mGluR2 (EC50: 285 nM).Formula:C25H28F3N5O6SPurezza:99.19%Colore e forma:SolidPeso molecolare:583.58(R)-ADX-47273
CAS:(R)-ADX-47273 is a potent mGluR5 positive allosteric modulator(EC50 of 168 nM for potentiation ).Formula:C20H17F2N3O2Purezza:99.87%Colore e forma:SolidPeso molecolare:369.36Ref: TM-T13441
2mg39,00€5mg62,00€1mL*10mM (DMSO)67,00€10mg88,00€25mg161,00€50mg245,00€100mg370,00€200mg515,00€VU0483605
CAS:VU0483605 is an effective and selective positive allosteric modulator of mGluR1 with EC50s of 390 and 356 nM for human and rat, respectively.Formula:C20H10Cl3N3O3Purezza:99.61%Colore e forma:SolidPeso molecolare:446.67Ref: TM-T21747
2mg39,00€5mg60,00€1mL*10mM (DMSO)73,00€10mg92,00€25mg173,00€50mg269,00€100mg404,00€200mg532,00€ML353
ML353 activates TREK-1/2, binds mGlu5 SAM (Ki=18.2 nM), surpasses 5mpep, may address SAM activity/blocking.Formula:C19H15FN2OPurezza:99.98% - 99.98%Colore e forma:SolidPeso molecolare:306.33Ref: TM-T67917
5mg50,00€1mL*10mM (DMSO)50,00€10mg74,00€25mg114,00€50mg156,00€100mg219,00€200mg298,00€NBQX disodium
CAS:NBQX Disodium (FG9202 disodium) is a highly selective, competitive AMPA receptor antagonist with neuroprotective and anticonvulsant activity.Formula:C12H6N4Na2O6SPurezza:97.32% - 97.6%Colore e forma:Brown SolidPeso molecolare:380.2415GYKI-47261 dihydrochloride
CAS:GYKI-47261 dihydrochloride is an AMPA receptor antagonist and CYP2E1 inducer, demonstrating broad-spectrum anticonvulsant and neuroprotective activities.Formula:C18H17Cl3N4Purezza:98.32% - 99.14%Colore e forma:White SolidPeso molecolare:395.71mGluR5 modulator 1
CAS:mGluR5 modulator 1 is a positive modulator for mGluR5, used in schizophrenia and cognitive research.Formula:C18H19ClFN3O2Colore e forma:SolidPeso molecolare:363.82DL-AP4
CAS:DL-AP4, also known as 2-Amino-4-phosphonobutyric acid, is a competitive glutamate antagonist with defined binding affinity that is widely used to selectively inhibit glutamatergic neurotransmission, making it an essential experimental compound for probing synaptic signaling mechanisms and functional circuitry in central nervous system and visual system research.Formula:C4H10NO5PPurezza:99.98%Colore e forma:White SolidPeso molecolare:183.1(S,S)-BMS-984923
CAS:(S,S)-BMS-984923 is a weak mGluR5 modulator with EC50 >1μM; less active than its potent counterpart.Formula:C22H15ClN2O2Colore e forma:SolidPeso molecolare:374.82LY3027788
CAS:LY3027788, potent oral prodrug of LY3020371, is a strong mGlu2/3 antagonist with notable antidepressant effects.Formula:C25H31F2NO11SColore e forma:SolidPeso molecolare:591.58
