GluR
Gli inibitori dei recettori del glutammato sono composti che bloccano l'attività dei recettori del glutammato, i principali recettori dei neurotrasmettitori eccitatori nel cervello. Questi recettori svolgono un ruolo cruciale nella trasmissione sinaptica, nella plasticità, nell'apprendimento e nella memoria. La disregolazione della segnalazione del glutammato è associata a vari disturbi neurologici, come l'epilessia, l'ictus e le malattie neurodegenerative. Gli inibitori dei recettori del glutammato sono essenziali per studiare i meccanismi dell'eccitotossicità e sviluppare strategie neuroprotettive. Presso CymitQuimica, offriamo una gamma di inibitori dei recettori del glutammato per supportare la vostra ricerca sulla funzione sinaptica, la neuroprotezione e i disturbi cognitivi.
Trovati 261 prodotti di "GluR"
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Org-26576
CAS:Org-26576 is a positive allosteric modulator of the AMPA receptor.Formula:C11H12N2O2Purezza:99.67%Colore e forma:SolidPeso molecolare:204.23(R)-ADX-47273
CAS:<p>(R)-ADX-47273 is a potent mGluR5 positive allosteric modulator(EC50 of 168 nM for potentiation ).</p>Formula:C20H17F2N3O2Purezza:99.87%Colore e forma:SolidPeso molecolare:369.36NBQX disodium
CAS:NBQX Disodium (FG9202 disodium) is a highly selective, competitive AMPA receptor antagonist with neuroprotective and anticonvulsant activity.Formula:C12H6N4Na2O6SPurezza:97.32% - 97.6%Colore e forma:SolidPeso molecolare:380.2415Basimglurant
CAS:<p>Basimglurant (CTEP Derivative) is a potent, selective and orally available modulator of mGlu5 negative allosteric(Kd of 1.1 nM).</p>Formula:C18H13ClFN3Purezza:98.35%Colore e forma:SolidPeso molecolare:325.77VU0650786
CAS:VU0650786: selective mGlu3 NAM, CNS-penetrant, IC50 392 nM, shows antidepressant/anxiolytic effects in rodents.Formula:C18H15ClFN5O2Purezza:99.09%Colore e forma:SolidPeso molecolare:387.8γ-DGG acetate(6729-55-1 free base)
CAS:gamma-DGG acetate(6729-55-1 free base) (γ-D-Glutamylglycine) is a competitive blocker of AMPA receptor.Formula:C9H16N2O7Purezza:99.81%Colore e forma:SolidPeso molecolare:264.23Decoglurant
CAS:<p>Decoglurant (RO4995819) is a negative allosteric modulator of mGluR2 and mGluR3 and it also is developed as an antidepressant.</p>Formula:C21H11F6N5Purezza:99.77%Colore e forma:SolidPeso molecolare:447.34KM02894
CAS:KM02894 inhibits glutamate release, potentially reducing cancer-induced bone pain in tumor studies.Formula:C7H9N3OS2Purezza:99.98%Colore e forma:SolidPeso molecolare:215.3LY339434 HCl
LY339434 HCl is a low affinity GluR5 erythrocyte receptor agonist.LY339434 HCl causes rapid neuronal death primarily by affecting N-methyl-D-aspartate (NMDA)Formula:C18H20ClNO4Purezza:97.10% - 97.19%Colore e forma:SoildPeso molecolare:349.81AZD-8529 mesylate
CAS:AZD-8529 mesylate is a highly selective, and orally bioavailable positive allosteric modulator of mGluR2 (EC50: 285 nM).Formula:C25H28F3N5O6SPurezza:99.19%Colore e forma:SolidPeso molecolare:583.58DHPG
CAS:DHPG is a potent Group I mGluR agonist; doesn't affect Group II/III; linked to phospholipase D.Formula:C8H9NO4Purezza:99.55%Colore e forma:SolidPeso molecolare:183.16(R)-3,4-DCPG HCl
<p>(R)-3,4-DCPG HCl is a potent and selective mGlu8a receptor agonist that activates metabotropic glutamate receptors on primary afferent terminals in the neonatal</p>Formula:C10H10ClNO6Purezza:98.80% - 99.89%Colore e forma:SoildPeso molecolare:275.64Piracetam
CAS:Piracetam (UCB-6215), a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), is used in therapy of the extensive cognitive disorders.Formula:C6H10N2O2Purezza:97.16%Colore e forma:Crystals From Isopropanol SolidPeso molecolare:142.16MMPIP hydrochloride
CAS:MMPIP hydrochloride is a selective antagonist of allosteric mGluR7.Formula:C19H16ClN3O3Purezza:99.88%Colore e forma:SolidPeso molecolare:369.8mGluR3 modulator-1
CAS:1-ethyl-3-morpholin-4-yl tetrahydroisoquinoline: mGluR3 modulator, potential for Parkinson's.Formula:C16H21N3OPurezza:98.99%Colore e forma:SolidPeso molecolare:271.36(S)-3,4-DCPG HCl
<p>(S)-3,4-DCPG HCl is a selective mGluR8a agonist, impacting AV12-664 cells with an EC50 of 31 nM.</p>Formula:C10H10ClNO6Purezza:99.53% - 99.9%Colore e forma:SoildPeso molecolare:275.64MGS0028
CAS:MGS0028 is a selective agonist of metabotropic glutamate 2/3 receptor, it could reverse abnormal behaviors in mice induced by isolation rearing.Formula:C8H8FNO5Colore e forma:SolidPeso molecolare:217.15(S)-3,4-DCPG
CAS:(S)-3,4-DCPG ((S)-3,4-Dicarboxyphenylglycine) is a selective agonist of human metabotropic glutamate receptor 8a (mGluR8a).Formula:C10H9NO6Purezza:98%Colore e forma:SolidPeso molecolare:239.18LY2812223
CAS:LY2812223: selective mGlu2 agonist; binds mGlu2/mGlu3 (Ki=144/156 nM).Formula:C10H12N4O4SPurezza:98%Colore e forma:SolidPeso molecolare:284.29VU0483605
CAS:<p>VU0483605 is an effective and selective positive allosteric modulator of mGluR1 with EC50s of 390 and 356 nM for human and rat, respectively.</p>Formula:C20H10Cl3N3O3Purezza:99.61%Colore e forma:SolidPeso molecolare:446.67GYKI-47261 dihydrochloride
CAS:<p>GYKI-47261 dihydrochloride is an AMPA receptor antagonist and CYP2E1 inducer, demonstrating broad-spectrum anticonvulsant and neuroprotective activities.</p>Formula:C18H17Cl3N4Purezza:98.32% - 99.14%Colore e forma:SolidPeso molecolare:395.71MPPG
CAS:MPPG is a selective L-AP4-sensitive receptor antagonist (kD=9.2 μM).Formula:C9H12NO5PColore e forma:SolidPeso molecolare:245.171(S,S)-BMS-984923
CAS:(S,S)-BMS-984923 is a weak mGluR5 modulator with EC50 >1μM; less active than its potent counterpart.Formula:C22H15ClN2O2Colore e forma:SolidPeso molecolare:374.82MGS0274
CAS:MGS0274, a lipophilic prodrug of mGlu2/3 agonist MGS0008, enhances oral bioavailability, potentially aiding schizophrenia research.Formula:C21H32FNO7Colore e forma:SolidPeso molecolare:429.485mGluR5 modulator 1
CAS:mGluR5 modulator 1 is a positive modulator for mGluR5, used in schizophrenia and cognitive research.Formula:C18H19ClFN3O2Colore e forma:SolidPeso molecolare:363.82Pomaglumetad methionil anhydrous
CAS:LY2140023, potential schizophrenia treatment, is an oral prodrug of LY404039, a selective mGlu2/3 agonist.Formula:C12H18N2O7S2Purezza:98%Colore e forma:SolidPeso molecolare:366.41KRP-199 sodium
<p>KRP-199 sodium sodium is highly potent and selective for AMPA-R in vitro and exhibits good neuroprotection in vivo.</p>Formula:C22H12F3N5Na2O7Purezza:97.27%Colore e forma:SoildPeso molecolare:561.33STX-107
CAS:<p>STX-107 is a potent and selective mGluR5 agonist for the study of Fragile X Syndrome.</p>Formula:C18H10FN3SPurezza:99.17%Colore e forma:SolidPeso molecolare:319.36LY3027788 hydrochloride
CAS:LY3027788 HCl, potent oral prodrug of LY3020371, targets mGlu2/3 with antidepressant effects.Formula:C25H32ClF2NO11SColore e forma:SolidPeso molecolare:628.03L-AP3
CAS:L-AP3 blocks mGluR, inhibits D/L-phosphoserine (IC50: 368/2087 μM).Formula:C3H8NO5PColore e forma:White Hygroscopic SolidPeso molecolare:169.073JF-NP-26
Releases pain-blocking raseglurant under 405 nm light. Inhibits Quisqualate. Analgesic in vivo. Quantum yield: 0.18.Colore e forma:SolidLY3027788
CAS:<p>LY3027788, potent oral prodrug of LY3020371, is a strong mGlu2/3 antagonist with notable antidepressant effects.</p>Formula:C25H31F2NO11SColore e forma:SolidPeso molecolare:591.58LY3020371
CAS:LY3020371: potent, selective mGlu 2/3 receptor antagonist with Ki of 5.26 nM (hmGluR2) and 2.50 nM (hmGluR3); key in depression studies.Formula:C15H15F2NO5SColore e forma:SolidPeso molecolare:359.341H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)-
CAS:<p>1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)- is a low activity isomer of S 18986.</p>Formula:C10H12N2O2SPurezza:99.96%Colore e forma:SoildPeso molecolare:224.28(±)-LY367385
CAS:(±)-LY367385 is the racemic form of LY367385, and LY367385 is a highly potent and selective mGluR1a antagonist.Formula:C10H11NO4Colore e forma:SolidPeso molecolare:209.201ML353
ML353 activates TREK-1/2, binds mGlu5 SAM (Ki=18.2 nM), surpasses 5mpep, may address SAM activity/blocking.Formula:C19H15FN2OPurezza:99.98% - 99.98%Colore e forma:SoildPeso molecolare:306.33DD205-291
CAS:DD205-291 is an orally active PROTAC HPK1 degrader with a DC50 of 5.3 nM. It inhibits SLP-76 phosphorylation and induces IL-2 and IFN-γ.Formula:C38H38ClF3N10O3Colore e forma:SolidPeso molecolare:775.22(S)-AMPA HCl
(S)-AMPA HCl (L-AMPA HCl) is a selective AMPA receptor agonist with potential antidepressant activity. It can be used in research on Parkinson's disease.Formula:C7H11ClN2O4Purezza:99.18%Colore e forma:SolidPeso molecolare:222.63VU0422288
CAS:<p>VU0422288 (ML396) is a type III mGlu receptor (mGlus) orthosteric modulator with inhibitory effects on mGluR4.VU0422288 can be used to study Rett syndrome.</p>Formula:C17H11Cl2N3O2Purezza:95.48%Colore e forma:SolidPeso molecolare:360.19NS-102
CAS:<p>NS-102 is a glutamate receptor and NMDA receptor antagonist that inhibits erythrocyanine (GluK2) and inhibits specific binding to the glur6 receptor.</p>Formula:C12H11N3O4Purezza:98.48% - 98.95%Colore e forma:SolidPeso molecolare:261.23LY487379
CAS:LY487379: human mGluR2 PAM, boosts glutamate binding, aids cognitive flexibility, may treat schizophrenia. EC50: 1.7 μM (mGlu2), >10 μM (mGlu3).Formula:C21H19F3N2O4SColore e forma:SolidPeso molecolare:452.45LY341495
CAS:LY341495 is a potent metabotropic glutamate receptor antagonist and can be used to study neurological disorders.Formula:C20H19NO5Purezza:98.53% - 99.37%Colore e forma:SolidPeso molecolare:353.37AMN082
CAS:AMN082 is an mGluR7 agonist with antidepressant effects. Neuroprotective effect of AMN082 on neuronal apoptosis in rats with traumatic brain injury.Formula:C28H30Cl2N2Purezza:97.13% - 98.63%Colore e forma:SolidPeso molecolare:465.46JNJ-46778212
CAS:JNJ-46778212 (VU 0409551) is a selective and potent mGlu5 allosteric modulator (EC50: 260 nM) for the study of neurodissection.Formula:C20H17FN2O3Purezza:99.24%Colore e forma:SolidPeso molecolare:352.36Ro 01-6128
CAS:Positive allosteric modulator of mGlu1 receptorsFormula:C17H17NO3Purezza:98%Colore e forma:SolidPeso molecolare:283.32GYKI 53655 hydrochloride
CAS:GYKI 53655 hydrochloride (LY300168 hydrochloride) is an antagonist of AMPA and is used in the study of neurological disorders.Formula:C19H21ClN4O3Purezza:98.02%Colore e forma:SolidPeso molecolare:388.85VU0364770 hydrochloride
CAS:VU0364770 hydrochloride: potent, selective mGlu4 PAM; EC50=290 nM (rat), 1.1 μM (human).Formula:C12H10Cl2N2OPurezza:98%Colore e forma:SolidPeso molecolare:269.13EGLU
CAS:EGLU, an antidepressant and potent mGluR-2 antagonist, binds with a 66 μM Kd to (lS,3S)-ACPD sites.Formula:C7H13NO4Purezza:99.98%Colore e forma:SolidPeso molecolare:175.18GYKI 52466 dihydrochloride
CAS:GYKI 52466 dihydrochloride is an AMPA/Kainate receptor antagonist with anticonvulsant activity and can be used to study neurological diseases.Formula:C17H17Cl2N3O2Purezza:99.38%Colore e forma:SolidPeso molecolare:366.24γ-DGG
CAS:gamma-DGG is a competitive blocker of AMPA receptor.Formula:C7H12N2O5Purezza:98%Colore e forma:SolidPeso molecolare:204.18CFMTI
CAS:<p>CFMTI: potent mGluR1 allosteric antagonist, 2000x selectivity over mGluR5, IC50: 2.6 nM.</p>Formula:C19H16FN5OPurezza:97.23%Colore e forma:SolidPeso molecolare:349.36E4CPG
CAS:E4CPG is a novel group I/II metabotropic glutamate receptor antagonist, more potent than (RS)-MCPG.Formula:C11H13NO4Purezza:99.96%Colore e forma:SolidPeso molecolare:223.23(S)-ATPO
CAS:<p>(S)-ATPO is Competitive antagonist at GluR1-4 (AMPA-preferring) receptors.</p>Formula:C11H19N2O7PPurezza:98.37% - 99.41%Colore e forma:SolidPeso molecolare:322.25FTIDC
CAS:FTIDC: potent, selective mGluR1 allosteric antagonist, weak on mGluR5. IC50: human 5.8 nM, mouse 3.1 nM. Noncompetitive.Formula:C18H23FN6OPurezza:94.58%Colore e forma:SolidPeso molecolare:358.41(RS)-3-Hydroxyphenylglycine
CAS:(RS)-3-Hydroxyphenylglycine is a PI-linked metabotropic glutamate receptors agonist.Formula:C8H9NO3Purezza:99.29%Colore e forma:SolidPeso molecolare:167.16VU-1545
CAS:VU-1545 is mGlu5 positive allosteric modulator.Formula:C22H15FN4O3Purezza:98.8%Colore e forma:SolidPeso molecolare:402.38DNQX
CAS:<p>DNQX (FG 9041) is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 μM for AMPA and kainate receptors, respectively)</p>Formula:C8H4N4O6Purezza:97.27% - 99.1%Colore e forma:Off-White Powder With A Yellow TingePeso molecolare:252.14VU0361737
CAS:VU0361737 (ML-128) is a mGlu4 PAM; EC50 is 240 nM (human) and 110 nM (rat), weak at mGlu5/8, inactive at mGlu1/2/3/6/7, CNS-penetrant.Formula:C13H11ClN2O2Purezza:99.60% - 99.85%Colore e forma:SolidPeso molecolare:262.69Farampator
CAS:Farampator (CX-691) (CX-691;Org24448) is a positive modulator of AMPA receptor.Formula:C12H13N3O2Purezza:99.84% - >99.99%Colore e forma:SolidPeso molecolare:231.25VU-29
CAS:VU-29 is a positive allosteric mGlu5 receptor modulator with EC50=9 nM and Ki=244 nM for rmGluR5. It is selective for mGluR5 relative to other mGluR subtypes.Formula:C22H16N4O3Purezza:99.63%Colore e forma:SolidPeso molecolare:384.39CX614
CAS:CX614 is a positive allosteric modulator of the AMPA receptor concerning AMPA.Formula:C13H13NO4Purezza:97.37%Colore e forma:SolidPeso molecolare:247.25Chelidamic acid
CAS:Chelidamic acid is a heterocyclic organic acid with a pyran skeleton. Chelidamic acid is inhibitors of glutamate decarboxylase, with a Ki of 33 μM.Formula:C7H5NO5Purezza:98.11%Colore e forma:Pale Yellow PowderPeso molecolare:183.12ADX-47273
CAS:<p>ADX-47273 (BA 94673139) is a positive and selective allosteric modulator for the metabotropic glutamate receptor subtype mGluR5(EC50=170 nM).</p>Formula:C20H17F2N3O2Purezza:97% - 99.18%Colore e forma:SolidPeso molecolare:369.36ADX88178
CAS:ADX88178 is a potent positive allosteric modulator for metabotropic glutamate receptor 4 (mGluR4) with EC50 of 4 nM for human mGluR4.Formula:C12H12N6SPurezza:99.55%Colore e forma:SolidPeso molecolare:272.33AZD-8529
CAS:AZD-8529: selective, oral mGluR2 modulator, EC50 285 nM; inactive on mGluR1,3-8 at 20-25 M.Formula:C24H24F3N5O3Colore e forma:SolidPeso molecolare:487.47XAP044
CAS:XAP044 blocks mGlu7, inhibiting long-term potentiation in mouse brain with a half-maximal effect at 88nm.Formula:C15H9IO4Purezza:97.41%Colore e forma:SolidPeso molecolare:380.13NBQX
CAS:<p>NBQX (FG9202) is a potent, selective and competitive AMPA receptor antagonist. Neuroprotective and anticonvulsant; active in vivo.</p>Formula:C12H8N4O6SPurezza:97.66% - 99.42%Colore e forma:SolidPeso molecolare:336.28JNJ16259685
CAS:JNJ16259685 (TN.T 16259685) is a selective mGluR1 antagonist, and inhibits the synaptic activation of mGluR1 in a concentration-dependent manner with IC50 of 19Formula:C20H23NO3Purezza:98.31%Colore e forma:SolidPeso molecolare:325.4CTEP
CAS:CTEP (RO 4956371) (RO4956371) is a novel, long-acting, orally bioavailable allosteric antagonist of mGlu5 receptor with IC50 of 2.2 nM, shows >1000-foldFormula:C19H13ClF3N3OPurezza:99.17%Colore e forma:SolidPeso molecolare:391.77MPEP
CAS:MPEP is a selective mGlu5 receptor antagonist with IC50 of 36 nM, exhibits no appreciable activity at mGlu1b/2/3/4a/7b/8a/6 receptors.Formula:C14H11NPurezza:99.54%Colore e forma:SolidPeso molecolare:193.24SIB-1757
CAS:<p>SIB-1757 (6-methyl-2-[(E)-phenyldiazenyl]pyridin-3) is a selective antagonist of mGlu5 metabotropic glutamate receptor subtype (hmGlu5, IC50 : 0.4 μM)</p>Formula:C12H11N3OPurezza:97.37%Colore e forma:SolidPeso molecolare:213.24MPEP hydrochloride
CAS:<p>MPEP hydrochloride is an effective and highly specific non-competitive antagonist at the mGlu5 receptor subtype (IC50: 36 nM).</p>Formula:C14H12ClNPurezza:99.87% - >99.99%Colore e forma:SolidPeso molecolare:229.7VU0364770
CAS:VU0364770 (VU 0364770)(EC50=1.1 μM), a positive allosteric modulator(PAM) of mGlu4, shows insignificant activity at 68 other receptors, including other mGluFormula:C12H9ClN2OPurezza:99.65% - >99.99%Colore e forma:SolidPeso molecolare:232.67(S)-3-Hydroxyphenylglycine
CAS:<p>(S)-3-Hydroxyphenylglycine is an agonist of group I metabotropic glutamate receptors (mGluRs).</p>Formula:C8H9NO3Purezza:99.65%Colore e forma:SolidPeso molecolare:167.16TCN238
CAS:<p>TCN238 is an orally bioavailable positive allosteric modulator of the metabotropic glutamate receptor 4 (mGluR4with an EC50 of 1 μM).</p>Formula:C12H11N3Purezza:99.9% - 99.92%Colore e forma:SolidPeso molecolare:197.24MTEP hydrochloride
CAS:<p>MTEP hydrochloride (MTEP) is non-competitive mGlu5 antagonist (IC50 and Ki of 5 nM and 16 nM, respectively)</p>Formula:C11H9ClN2SPurezza:99.58%Colore e forma:SolidPeso molecolare:236.721-BCP
CAS:1-BCP (Piperonylic acid piperidide) is a centrally active drug that modulates AMPA receptor gated currents.Formula:C13H15NO3Purezza:99.60%Colore e forma:SolidPeso molecolare:233.26PHCCC
CAS:<p>PHCCC is a Group I mGluR antagonist and enhances mGluR4 function; also blocks mGluR2/8.</p>Formula:C17H14N2O3Purezza:>99.99%Colore e forma:SolidPeso molecolare:294.3Lu AF21934
CAS:<p>Lu AF21934 is a brain-penetrant and selective mGlu4 receptor positive allosteric modulator (IC50: 500 nM, human).</p>Formula:C14H16Cl2N2O2Purezza:99.79%Colore e forma:SolidPeso molecolare:315.2trans-ACPD
CAS:trans-ACPD ((±)-trans-ACPD) is an equimolecular mixture of (1S, 3R)- and (1R, 3S)-ACPD.Formula:C7H11NO4Purezza:99.53%Colore e forma:SolidPeso molecolare:173.17IDRA-21
CAS:IDRA-21 is a positive AMPA receptor modulator.Formula:C8H9ClN2O2SPurezza:99.73%Colore e forma:SolidPeso molecolare:232.69LY-404187
CAS:LY404187 is a positive allosteric modulator of AMPA receptorsFormula:C19H22N2O2SPurezza:99.34%Colore e forma:SolidPeso molecolare:342.46HBT1
CAS:<p>HBT1 is an AMPA receptor potentiator that induces production of brain-derived neurotrophic factor (BDNF) and exhibits little agonistic effect in primary neurons</p>Formula:C16H17F3N4O2SPurezza:99.52%Colore e forma:SolidPeso molecolare:386.39Ro0711401
CAS:Ro0711401 is an agonist of mGlu1 receptor.Formula:C18H11F3N2O3Purezza:97.57%Colore e forma:SolidPeso molecolare:360.29VU 0357121
CAS:VU0357121, a positive allosteric modulator of mGlu5 (EC50: 33 nM), is inactive or very weakly antagonizing at other mGlu receptor subtypes.Formula:C17H17F2NO2Purezza:99% - >99.99%Colore e forma:SolidPeso molecolare:305.32YM90K
CAS:YM90K (6-(1H-imidazol-1-yl)-7-nitro-2,3(1H,4H)-) hydrochloride is an antagonist of AMPA receptor.Formula:C11H8ClN5O4Purezza:98.23%Colore e forma:SolidPeso molecolare:309.66FITM
CAS:FITM is a potent negative allosteric modulator of mGlu1 receptor(Ki : 2.5 nM).Formula:C18H18FN5OSPurezza:97.25%Colore e forma:SolidPeso molecolare:371.43AMN082 free base
CAS:AMN082 free base is a metabotropic glutamate receptor 7 allosteric agonist.Formula:C28H28N2Purezza:97.75% - 97.79%Colore e forma:SolidPeso molecolare:392.54ML 254
CAS:<p>是一种化学合成中的砌块</p>Formula:C18H15FN2O2Purezza:98.09%Colore e forma:SolidPeso molecolare:310.32MTEP
CAS:MTEP: potent, selective mGluR5 antagonist; IC50=5 nM, Ki=16 nM; may have antidepressant/anxiolytic effects; useful in Parkinson's research.Formula:C11H8N2SColore e forma:SolidPeso molecolare:200.26CX516
CAS:CX516 (Ampalex), an ampakine and nootropic, acts as an AMPA receptor positive allosteric modulator as a therapy for Alzheimer's disease, schizophrenia and MCI.Formula:C14H15N3OPurezza:99.04% - ≥95%Colore e forma:Tan SolidPeso molecolare:241.29CNQX
CAS:CNQX (FG9065) is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.3 and 1.5 μM for AMPA and kainate receptors, respectively)Formula:C9H4N4O4Purezza:99.70%Colore e forma:Pale Yellow SolidPeso molecolare:232.15(RS)-MCPG
CAS:<p>(RS)-MCPG ((±)-MCPG) is a non-selective group I/II metabotropic glutamate receptor antagonist.</p>Formula:C10H11NO4Purezza:99.96%Colore e forma:SolidPeso molecolare:209.2Ro 67-7476
CAS:Ro 67-7476 is a positive allosteric modulator of mGlu1 receptors.Formula:C17H18FNO2SPurezza:99.69%Colore e forma:SolidPeso molecolare:319.393-MATIDA
CAS:<p>3-MATIDA is an effective mGluR-1 antagonist (IC50: 6.3 μM, rat mGluR-1a).</p>Formula:C8H9NO4SPurezza:99.75% - 99.96%Colore e forma:SolidPeso molecolare:215.23VU0155094
CAS:<p>VU0155094 (ML 397) is a positive allosteric modulator with differential activity at the various group III mGluRs.</p>Formula:C24H24N2O4SPurezza:97.21%Colore e forma:SolidPeso molecolare:436.52Caroverine hydrochloride
CAS:Caroverine HCL: Blocks NMDA/AMPA receptors, antioxidant, calcium-blocker, and vasorelaxant, used for tinnitus research.Formula:C22H28ClN3O2Purezza:98.37% - 98.75%Colore e forma:SolidPeso molecolare:401.9VU 0364439
CAS:VU 0364439 is a mGlu4 positive allosteric modulator (C50: 19.8 nM).Formula:C18H13Cl2N3O3SPurezza:97.9%Colore e forma:SolidPeso molecolare:422.29JNJ-42153605
CAS:<p>JNJ-42153605 is a mGlu2 receptor positive allosteric modulator (EC50: 17 nM).</p>Formula:C22H23F3N4Purezza:97.25% - 98.57%Colore e forma:SolidPeso molecolare:400.44VU0155041
CAS:VU0155041 is an effective and positive allosteric modulator/allosteric agonist at mGlu4 receptors (EC50: 798/693 nM, at human/rat).Formula:C14H15Cl2NO3Purezza:99.52% - 99.56%Colore e forma:SolidPeso molecolare:316.18
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